Helminth Introduction 160619043259

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INSTITUTE OF PULIC HEALTH, DHAKA

Department of Laboratory Medicine


BSc in Health Technology (Laboratory)- 1st Year

HELMINTHOLOGY
Lecture No. 01(Introduction)

By

Sk. MIZANUR RAHMAN


Assistant Bacteriologist, MBL, IPH
MS in Biotechnology & Genetic Engineering (UODA)
MS in Microbiology (SU)
MPH in Epidemiology (SUB)
Norman Stoll, President of the
American Society of
Parasitologists
1947 inaugural address
“This wormy world”

Called for a world-wide


effort to control worm
infections
Method of Learning
• Terminology
• Introduction
• Classification
• Characteristics
• Differences between the classes
• Example and Life cycles
HELMINTH/WORM TERMINOLOGY
• Adults: sexually reproductive life cycle stage
• Larvae: developmental or asexually reproductive life
cycle stage
• Eggs: stage protective of zygote &/or embryo
• Cysts: usually a larval stage encapsulated in tissues
of an intermediate host
• Hypobiosis: worms in temporary developmental
arrest
• Monoecious/hermaphroditic: both sexes 1 body
• Dioecious: sexes separate; males & females
• Parthenogenesis: ability to produce offspring
without fertilization of eggs
Helminths, continued

Worm-terms, continued
• Oviparous: production of eggs, discharged from
uterus of female
• Ovoviviparous: production of eggs which hatch
prior to discharge from uterus of female
• Viviparous: production of embryos/L1 larvae, no
rigid encapsulation of embryo
Introduction to helminth
• Helminth means worm. Their motile activity is
accomplished by wriggling movement. The helminth of
medical importance belong to 3 classes: Nematoda,
Trematoda and Cestoda.
• Helminthology is the study of parasitic worms and their
effect on their hosts.
• Geohelminths refer to the helminths which complete
their life cycles not requiring the processes of the
development in intermediate hosts. They have only one
host and a simple life cycle, such as ascarid, hookworm,
pinworm and etc.
• Biohelminths refer to those that have to undergo the
development in intermediate hosts to complete their life
cycle , such as filaria, liver fluke, pork tapeworm and so on.
Taxonomic classification of helminths
Sub Phylum Class Genus – examples
kingdom
Metazoa Nematodes Ascaris (roundworm)
Round worms; appear round in Trichuris (whipworm)
cross section, they have body Ancylostoma (hookworm)
cavities, a straight alimentary Necator (hookworm)
canal and an anus Enterobius (pinworm or
threadworm)
Strongyloides

Platyhelminthes Cestodes Taenia (tapeworm)


Flat worms; dorsoventrally Adult tapeworms are found in the
flattened, no body cavity and, if intestine of their host
present, the alimentary canal is They have a head (scolex) with
blind ending sucking organs, a segmented body
but no alimentary canal
Each body segment is
hermaphrodite

Trematodes Fasciolopsis (liver fluke)


Non-segmented, usually leaf- Schistosoma (not leaf
shaped, with two suckers but no shaped!)
distinct head
They have an alimentary canal and
are usually hermaphrodite and leaf
shaped
Schistosomes are the exception.
They are thread-like, and have
separate sexes
HELMINTHS (WORMS)
Characteristics
 Eukaryotic (N+CW), multicellular animals that usually have
digestive, circulatory, nervous, excretory, and reproductive
systems.
 Worms with bilateral symmetry, head and tail, and tissue
differentiation (endoderm, mesoderm, and ectoderm).
 Parasitic helminths spend most or all of their lives in host
and usually have the following specializations:
– May lack a digestive system. Absorb nutrients from host’s food,
body fluids, or tissues.
– Have a reduced nervous system.
– Means of locomotion is reduced or absent.
– Complex reproductive system. Individuals produce many eggs that
can infect another host.
Helminthes
Cestodes Trematodes Nematodes

Shape Segmented plane Unsegmented plane Cylindrical

Body cavity No No Present

Digestive tube No Ends in cecum Ends in anus

Hermaphroditic - Dioecious-
Taenia Hermaphroditic, except Ascaris
Sex Schistosoma which
(tapeworm) are dioecious (roundworm)

Oral sucker, botridias, Lips, teeth, filariform


hook organ Oral sucker and ventral
and double extremities, and
component sucker
Rostellar hooks dentary plates
Helminths (Worms): Some Important Ones
Most acquired from ingestion of or contact with feces-contaminated soil or
food
• Nematodes (Roundworms):
– Ascaris lumbricoides GI illness; pneumonitis
– Trichuris trichuria chronic GI
• Hookworms:
– Ancylostoma duodenale chronic anemia
– Necator americanus chronic anemia
– Strongyloides stercoralis chronic anemia
• Cestodes (tapeworms):
– Hymenolepis nana GI illness

Worm burdens tend to be low in the United States; little illness occurs
Still major causees of illness in developing countries
Examples of important metazoa – intestinal nematodes
• Trichuris (whipworm)
• Ascaris (roundworm)
– A soil transmitted helminth – Found world-wide in conditions of
– prevalent in warm, humid conditions poor hygiene, transmitted by the
faecal- oral route
– Can cause diarrhoea, rectal prolapse – Adult worms lives in the small
and anaemia in heavily-infected intestine
people – Causes eosinophilia

• Ancylostoma and Necator (hookworms)


– A major cause of anaemia in the
tropics

• Strongyloides
– inhabits the small bowel
– infection more severe in
immunospressed people (e.g.
HIV/AIDS, malnutrition, intercurrent
disease)

• Enterobius (pinworm or threadworm) Heavy intestinal infections may occur


– prevalent in cold and temperate with Ascaris. Adult worms can be
climates but rare in the tropics several cms long.
– found mainly in children
Learning method
Infective name Pathogenesis
stage route Prevention
mode
Life cycle Pathogenic name Pathogenesis
stage localization Treatment
migration Diagnosis
Diagnostic stage-morphology Diagnosis
stage methods
stage outside name Epidemiology
(vector, other host) name Prevention

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