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    Concept Map - Rheumatoid Arthritis

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    Janhavi Hiwase
    The patient is a 40-year-old with a history of rheumatoid arthritis experiencing an acute exacerbation. They present with morning stiffness, tenderness, and joint swelling over the past 6 months. On examination, they have tender and swollen joints, stiffness, fatigue, fever, and appetite loss. Risk factors for their condition include obesity, age, smoking, genetics. They have been prescribed methotrexate, an oral DMARD, and oral prednisone, a corticosteroid, to manage their symptoms and the underlying inflammatory process. Both drugs work to reduce inflammation through different mechanisms of action and pharmacodynamics.

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    Concept Map - Rheumatoid Arthritis

    Uploaded by

    Janhavi Hiwase
    269 views1 page
    The patient is a 40-year-old with a history of rheumatoid arthritis experiencing an acute exacerbation. They present with morning stiffness, tenderness, and joint swelling over the past 6 months. On examination, they have tender and swollen joints, stiffness, fatigue, fever, and appetite loss. Risk factors for their condition include obesity, age, smoking, genetics. They have been prescribed methotrexate, an oral DMARD, and oral prednisone, a corticosteroid, to manage their symptoms and the underlying inflammatory process. Both drugs work to reduce inflammation through different mechanisms of action and pharmacodynamics.

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    Concept map _ Rheumatoid Arthritis

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    The patient is a 40-year-old with a history of rheumatoid arthritis experiencing an acute exacerbation. They present with morning stiffness, tenderness, and joint swelling over the past 6 months. On examination, they have tender and swollen joints, stiffness, fatigue, fever, and appetite loss. Risk factors for their condition include obesity, age, smoking, genetics. They have been prescribed methotrexate, an oral DMARD, and oral prednisone, a corticosteroid, to manage their symptoms and the underlying inflammatory process. Both drugs work to reduce inflammation through different mechanisms of action and pharmacodynamics.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    269 views1 page

    Concept Map - Rheumatoid Arthritis

    Uploaded by

    Janhavi Hiwase
    The patient is a 40-year-old with a history of rheumatoid arthritis experiencing an acute exacerbation. They present with morning stiffness, tenderness, and joint swelling over the past 6 months. On examination, they have tender and swollen joints, stiffness, fatigue, fever, and appetite loss. Risk factors for their condition include obesity, age, smoking, genetics. They have been prescribed methotrexate, an oral DMARD, and oral prednisone, a corticosteroid, to manage their symptoms and the underlying inflammatory process. Both drugs work to reduce inflammation through different mechanisms of action and pharmacodynamics.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 1

    Chief Complaints P.E.

    – Acute exacerbation of Rheumatoid Arthritis


    • Morning stiffness
    • Tenderness Signs & Symptoms Risk Factors Prescribed -
    • Joint swelling (6 months) Tender, swollen joints, Obesity, age,
    stiffness, Fatigue, fever smoking, genetics,
    Age – 40 year and loss of appetite etc. Methotrexate Oral prednisone
    Class - DMARDs Class – corticosteroids
    Past History - Rheumatoid Arthritis Treatment Management
    Exercise
    Medication Indication – Arthritis, Psoriasis Indication – Anti-inflammatory or
    (other regularly.
    Contraindication – pregnancy, allergic,
    immunosuppressive drug for
    Apply heat or
    Self Medicated Drugs DMARDs) ,
    physiothera cold. haptic disease, etc.
    rheumatoid conditions
    Contraindication – hypersensitivity
    py, surgery Relax. Adverse effects – dizziness, Adverse effects – High BP,
    Paracetamol Ibuprofen headache, hair loss, etc. psychological effects, etc

    No Anti- Risk of stomach bleeding, MOA / Pharmacodynamics MOA / Pharmacodynamics


    • inhibit aminoimidazole-4-carboxamide • inhibiting pro-inflammatory signals
    inflammatory ulcers, no effect on joint ribonucleotide (AICAR) transformylase • promoting anti-inflammatory
    effects destruction (ATIC) signals
    • inhibits dihydrofolate reductase
    Discontinued
    Indication of using NSAIDS Pharmacokinetics Pharmacokinetics
    Reduce pain, inflammation, swelling, fever in half life - 2.1-3.5 hours
    half life - 8 to 15 hours
    types of arthritis & musculoskeletal disorders bioavailability of 64-90% eliminated in urine

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