DRUGS OF CHOICE

CONDITION/SCENARIO DRUG OF CHOICE CLASS OF DRUG

AUTONOMIC NERVOUS SYSTEM
ORGANOPHOSPHATE POISONING ATROPINE ANTI MUSCARINIC
NICOTINE POISONING ATROPINE ANTI MUSCARINIC
MUSHROOM POISONING ATROPINE ANTI MUSCARINIC
ATROPINE/BELLODONNA POISONING PHYSOSTIGMINE TERTIARY AMINE - CARBAMATES
DATURA POISONING PHYSOSTIGMINE TERTIARY AMINE - CARBAMATES
DIAGNOSIS OF MYASTHENIA GRAVIS EDROPHONIUM (TENSILON TEST) QUARTERNARY AMINE - CARBAMATES
GENERALISED MYASTHENIA GRAVIS PYRIDOSTIGMINE QUARTERNARY AMINE - CARBAMATES
OCULAR MYASTHENIA GRAVIS PYRIDOSTIGMINE QUARTERNARY AMINE - CARBAMATES
MYASTHENIC CRISIS i.v. IMMUNOGLOBULINS
NARCO ANALYSIS THIOPENTONE BARBITURATE
XEROSTOMIA CEVIMELINE > PILOCARPINE MUSCARINIC AGONIST
MOTION SICKNESS SCOPOLAMINE PATCH ANTI MUSCARINIC
URGE INCONTINENCE DARIFENACINE ANTI MUSCARINIC
STRESS INCONTINENCE DULOXETINE α1 AGONIST
OVERFLOW INCONTINENCE NEOSTIGMINE / BETHANECHOL M3 AGONIST
PARALYTIC ILEUS BETHANECHOL M3 AGONIST
COCAINE POISONING DIAZEPAM BENZODIAZEPINES
COCAINE DEPENDANCE BROMOCRIPTINE DOPAMINE AGONIST
HUNTINGTON'S CHOREA TETRABENAZINE VMAT-2 BLOCKER
TARDIVE DYSKINESIA VALBENAZINE / TETRABENAZINE VMAT-2 BLOCKER
ANAPHYLACTIC SHOCK i.m. EPINEPHRINE CATECHOLAMINES
SEPTIC SHOCK / VASODILATORY SHOCK i.v. NOREPINEPHRINE CATECHOLAMINES
BRITTLE ASTHMA EPINEPHRINE CATECHOLAMINES
CARDIAC ARREST (ACLA GUIDELINES) EPINEPHRINE CATECHOLAMINES
CARDIOGENIC SHOCK NOREPINEPHRINE > DOPAMINE CATECHOLAMINES
CHF WITH OLIGURIA DOPAMINE CATECHOLAMINES
ACUTE CHF DOBUTAMINE CATECHOLAMINES
STRESS ECHO DOBUTAMINE CATECHOLAMINES
NEUROGENIC HYPOTENSION DROXIDOPA CATECHOLAMINES
PRIAPISM PHENYLEPHRINE (Intracavernosal) α1 AGONIST
ACUTE POSTURAL HYPOTENSION MIDODRINE α1 AGONIST

Compiled by
Dr. Bhargav Shreeram G.
 DRUGS OF CHOICE

LONG TERM POSTURAL HYPOTENSION FLUDROCORTISONE CORTICOSTEROIDS

HYPERTENSIVE URGENCY CLONIDINE α2 AGONIST
TICS WITH TOURETTE SYNDROME CLONIDINE α2 AGONIST
PREGNANCY INDUCED HYPERTENSION LABETALOL β BLOCKER
HYPOTENSION WITH SPINAL ANESTHESIA EPHEDRINE INDIRECT SYMPATHOMIMETIC
ADHD METHYLPHENIDATE INDIRECT SYMPATHOMIMETIC
ADHD WITH TOURETTE SYNDROME ATOMOXETINE INDIRECT SYMPATHOMIMETIC
ADHD WITH FAMILY H/O DRUG ABUSE ATOMOXETINE INDIRECT SYMPATHOMIMETIC
NARCOLEPSY MODAFINIL
CLONIDINE WITHDRAWAL HYPERTENSION PHENTOLAMINE NON SELECTIVE α BLOCKER
CHEESE REACTION PHENTOLAMINE NON SELECTIVE α BLOCKER
INTRAOPERATIVE HYPERTENSION IN PHEOCHROMOCYTOMA PHENTOLAMINE NON SELECTIVE α BLOCKER
PREOPERATIVE HYPERTENSION IN PHEOCHROMOCYTOMA PHENOXYBENZAMINE NON SELECTIVE α BLOCKER
BENIGN PROSTATIC HYPERPLASIA ALFUZOSIN α1a BLOCKER
BPH WITH HYPERTENSION DOXAZOSIN α1 BLOCKER
HYPERTENSION WITH DYSLIPIDEMIA DOXAZOSIN α1 BLOCKER
SCORPION BITE PRAZOSIN α1 BLOCKER
HYPERTENSION WITH ANXIETY PROPRANOLOL β BLOCKER
HYPERTENSION WITH HYPERTHYROIDISM PROPRANOLOL β BLOCKER
HYPERTENSION WITH MIGRAINE PROPRANOLOL β BLOCKER
HYPERTENSION WITH H/o MI PROPRANOLOL β BLOCKER
HYPERTENSION WITH CHRONIC CHF PROPRANOLOL β BLOCKER
HYPERTENSION WITH STABLE ANGINA PROPRANOLOL β BLOCKER
PROPHYLAXIS OF MIGRAINE PROPRANOLOL β BLOCKER
STABLE ANGINA PROPRANOLOL β BLOCKER
PROPHYLAXIS OF STABLE ANGINA PROPRANOLOL β BLOCKER
AORTIC DISSECTION PROPRANOLOL β BLOCKER
HYPERTROPHIC OBSTRUCTIVE CARDIOMYOPATHY PROPRANOLOL β BLOCKER
PROPHYLAXIS OF ACUTE VARICEAL BLEED PROPRANOLOL β BLOCKER
ULCERATED INFANTILE HEMANGIOMA PROPRANOLOL β BLOCKER
ESSENTIAL TREMOR PROPRANOLOL β BLOCKER
BETA BLOCKER POISONING GLUCAGON

Compiled by
Dr. Bhargav Shreeram G.
 DRUGS OF CHOICE

OPEN ANGLE GLAUCOMA LATANOPROST PGF2α ANALOGUE

NORMAL TENSION GLAUCOMA LATANOPROST PGF2α ANALOGUE
ACUTE CONGESTIVE GLAUCOMA ACETAZOLAMIDE CARBONIC ANHYDRASE INHIBITOR
CYCLOPLEGIA - ADULTS TROPICAMIDE ANTI MUSCARINIC
CYCLOPLEGIA - CHILDREN ATROPINE ANTI MUSCARINIC
FAMILIAL HYPERKALEMIC PERIODIC PARALYSIS DICHLORPHENAMIDE CARBONIC ANHYDRASE INHIBITOR
INCREASED ICP HEADACHE
ACETAZOLAMIDE CARBONIC ANHYDRASE INHIBITOR
(PSEUDOTUMOR CEREBRI)
MOUNTAIN SICKNESS ACETAZOLAMIDE CARBONIC ANHYDRASE INHIBITOR

AUTOCOIDS
MORNING SICKNESS DOXYLAMINE ANTI HISTAMINIC
HAY FEVER (ALLERGIC RHINITIS) CORTICOSTEROIDS
URTICARIA SECOND GENERATION ANTI HISTAMINICS
ACUTE ATTACK OF MIGRAINE SUMATRIPTAN 5HT 1B/1D AGONIST
CLUSTER HEADACHE SUMATRIPTAN 5HT 1B/1D AGONIST
PROPHYLAXIS OF CLUSTER HEADACHE VERAPAMIL CALCIUM CHANNEL BLOCKER
HEREDITARY ANGIOEDEMA - TREATMENT C1 ESTERASE INHIBITOR
HEREDITARY ANGIOEDEMA - PROPHYLAXIS DANAZOL TESTOSTERONE ANALOGUE
HEREDITARY TREATMENT PROPHYLAXIS - PRIOR TO SURGERY € AMINO CAPROIC ACID ANTI FIBRINOLYTICS
CERVICAL RIPENING DINOPROSTONE PGE2 ANALOGUE
PARACETAMOL POISONING N ACETYLCYSTEINE
NIACIN INDUCED FLUSHING ASPIRIN NON-SELECTIVE COX INHIBITOR
ACUTE GOUT INDOMETHACIN NON-SELECTIVE COX INHIBITOR
BARTTER SYNDROME INDOMETHACIN NON-SELECTIVE COX INHIBITOR
PAROXYSMAL HEMICRANIA INDOMETHACIN NON-SELECTIVE COX INHIBITOR
CLOSURE OF PATENT DUCTUS ARTERIOSUS IBUPROFEN NON-SELECTIVE COX INHIBITOR
FAMILIAL MEDITERRANEAN FEVER COLCHICINE MICROTUBULE INHIBITOR
CHRONIC GOUT ALLOPURINOL XANTHINE OXIDASE INHIBITOR
TUMOR LYSIS SYNDROME PROPHYLAXIS ALLOPURINOL XANTHINE OXIDASE INHIBITOR

CARDIOVASCULAR SYSTEM

Compiled by
Dr. Bhargav Shreeram G.
 DRUGS OF CHOICE

ACUTE ATTACK OF SVT/PSVT ADENOSINE

PROPHYLAXIS OF SVT/PSVT PROPRANOLOL β BLOCKER
WPW SYNDROME WITH ATRIAL FIBRILLATION PROCAINAMIDE CLASS 1A ANTI ARRHYTHMIC
WPW SYNDROME RF ABLATION > FLECAINIDE CLASS 1C ANTI ARRHYTHMIC
DIGOXIN INDUCED VT / V. FIBRILLATION LIDOCAINE CLASS 1B ANTI ARRHYTHMIC
MI INDUCED VT / V. FIBRILLATION LIDOCAINE CLASS 1B ANTI ARRHYTHMIC
IDIOPATHIC VT PROPRANOLOL β BLOCKER
VENTRICULAR PREMATURE BEATS PROPRANOLOL β BLOCKER
RATE CONTROL IN ATRIAL FIBRILLATION - STABLE PT METOPROLOL β BLOCKER
RATE CONTROL IN ATRIAL FIBRILLATION - UNSTABLE PT ESMOLOL β BLOCKER
RHYTHM CONTROL IN ATRIAL FIBILLATION/FLUTTER AMIODARONE CLASS 3 ANTI ARRHYTHMIC
ANTI ARRHYTHMIC OF CHOICE IN ACLS PROTOCOL AMIODARONE CLASS 3 ANTI ARRHYTHMIC
VENTRICULAR TACHYCARDIA AMIODARONE CLASS 3 ANTI ARRHYTHMIC
VENTRICULAR FIBRILLATION AMIODARONE CLASS 3 ANTI ARRHYTHMIC
ACUTE ATTACK OF ATRIAL FIB / ATRIAL FLUTTER DC CARDIOVERSION
PSVT WITH BRONCHIAL ASTHMA VERAPAMIL CLASS 4 ANTI ARRHYTHMIC
PSVT WITH COPD VERAPAMIL CLASS 4 ANTI ARRHYTHMIC
LONG QT SYNDROME - PROPHYLAXIS PROPRANOLOL β BLOCKER
LONG QT SYNDROME - ACUTE ATTACK MAGNESIUM SULPHATE
BRADYARRHYTHMIA d/t IWMI ATROPINE ANTI MUSCARINIC
BRADYARRHYTHMIA d/t SINUS ARREST ATROPINE ANTI MUSCARINIC
ACUTE CHF WITH PULMONARY EDEMA FUROSEMIDE DIURETIC
RIGHT SIDED HEART FAILURE MILRINONE PDE 3 INHIBITOR
RAYNAUD'S DISEASE VERAPAMIL CALCIUM CHANNEL BLOCKER
HYPERTENSIVE EMERGENCY i.v. NICARDIPINE CALCIUM CHANNEL BLOCKER
HYPERTENSIVE EMERGENCY IN PREGNANCY i.v. LABETOLOL β BLOCKER
INSULINOMA DIAZOXIDE POTASSIUM CHANNEL OPENER
ACUTE ATTACK OF ANGINA sl. NITROGLYCERIN VENODILATOR
PROPHYLAXIS OF ANGINA PAIN IN MI sl. NITROGLYCERIN VENODILATOR
CYANIDE POISONING AMYL NITRITE VENODILATOR
MALIGNANT HYPERTENSION SODIUM NITROPRUSSIDE MIXED VASODILATOR
HYPERTENSION WITH DM ACEI / ARB
HYPERTENSION WITH CKD ACEI / ARB

Compiled by
Dr. Bhargav Shreeram G.
 DRUGS OF CHOICE

HYPERTENSION WITH NEPHROTIC SYNDROME ACEI / ARB

HYPERTENSION WITH SCLERODERMA ACEI / ARB
HYPERTENSION WITH BILATERAL RENAL STENOSIS CALCIUM CHANNEL BLOCKER
HYPERTENSION - YOUNG PATIENT ACEI / ARB
HYPERTENSION - OLD PATIENT CALCIUM CHANNEL BLOCKER
HYPERTENSION WITH OSTEOPOROSIS CHLORTHALIDONE THIAZIDES
RESISTANT HYPERTENSION SPIRONOLACTONE ALDOSTERONE ANTAGONIST
RESISTANT EDEMA SPIRONOLACTONE ALDOSTERONE ANTAGONIST
CIRRHOTIC EDEMA SPIRONOLACTONE ALDOSTERONE ANTAGONIST
CEREBRAL EDEMA MANNITOL OSMOTIC DIURETICS
PULMONARY EDEMA FUROSEMIDE LOOP DIURETICS

ENDOCRINE SYSTEM
TYPE II HYPERLIPOPROTEINEMIA STATINS
TYPE II HYPERLIPOPROTEINEMIA IN PREGNANCY / CHILDREN BILE ACID BINDING RESINS
HYPERCHYLOMICRONEMIA
FIBRATES
TYPE I HYPERLIPOPROTEINEMIA
TYPE III HYPERLIPOPROTEINEMIA FIBRATES
HYPERTRIGLYCERIDEMIA /
FIBRATES
TYPE IV HYPERLIPOPROTEINEMIA
DIABETIC KETOACIDOSIS REGULAR INSULIN
TYPE 2 DIABETES MELLITUS METFORMIN BIGUANIDES
ACROMEGALY OCTREOTIDE SOMATOSTATIN ANALOGUE
ACUTE VARICEAL BLEED OCTREOTIDE SOMATOSTATIN ANALOGUE
SECRETORY DIARRHOEA (HIV/TUMOR/CHEMOTHERAPY) OCTREOTIDE SOMATOSTATIN ANALOGUE
GLUCAGONOMA OCTREOTIDE SOMATOSTATIN ANALOGUE
VIPOMA OCTREOTIDE SOMATOSTATIN ANALOGUE
SOMATOSTATINOMA OCTREOTIDE SOMATOSTATIN ANALOGUE
CARCINOID SYNDROME OCTREOTIDE SOMATOSTATIN ANALOGUE
GnRH AGONIST + ANDROGEN RECEPTOR
PROSTATE CANCER Continous Dosage of GOSERELIN + FLUTAMIDE
ANTAGONIST
RIEDELS THYROIDITIS TAMOXIFEN SERM

Compiled by
Dr. Bhargav Shreeram G.
 DRUGS OF CHOICE

ER +VE BREAST CANCER IN PRE MENOPAUSAL WOMEN TAMOXIFEN SERM

ER +VE BREAST CANCER IN POST MENOPAUSAL WOMEN LETROZOLE AROMATASE INHIBITOR
ANDROGENIC ALOPECIA FINASTERIDE 5α REDUCTASE INHIBITOR
HYPERTHYROIDISM METHIMAZOLE THYROID PEROXIDASE INHIBITOR
HYPERTHYROIDISM IN PREGNANCY (2nd & 3rd TRIMESTER) METHIMAZOLE THYROID PEROXIDASE INHIBITOR
HYPERTHYROIDISM IN PREGNANCY (1st TRIMESTER) PROPYL THIOURACIL THYROID PEROXIDASE INHIBITOR
SEVERE THYROTOXICOSIS / THYROID STORM PROPYL THIOURACIL THYROID PEROXIDASE INHIBITOR
HYPOTHYROIDISM LEVOTHYROXINE SODIUM SALT OF T4
SUBACUTE / DEQUERVAIN THYROIDITIS ASPIRIN NON-SELECTIVE COX INHIBITOR
CONGENITAL ADRENAL HYPERPLASIA (CAH) HYDROCORTISONE CORTICOSTEROIDS
ANTENATAL PROPHYLAXIS OF CAH DEXAMETHASONE CORTICOSTEROIDS
PRIMARY ADDISON'S DISEASE HYDROCORTISONE + FLUDROCORTISONE CORTICOSTEROIDS
SECONDARY ADDISON'S DISEASE HYDROCORTISONE CORTICOSTEROIDS
OSTEOPOROSIS ZOLENDRONATE BISPHOSPHONATES
HYPERCALCEMIA OF MALIGNANCY ZOLENDRONATE BISPHOSPHONATES
PAGETS DISEASE ZOLENDRONATE BISPHOSPHONATES
POST PARTUM HEMORRHAGE OXYTOCIN

CENTRAL NERVOUS SYSTEM

GENERALIZED TONIC CLONIC SEIZURES SODIUM VALPROATE CALCIUM CHANNEL BLOCKER
MYOCLONIC SEIZURES SODIUM VALPROATE CALCIUM CHANNEL BLOCKER
ATONIC / AKINETIC SEIZURES SODIUM VALPROATE CALCIUM CHANNEL BLOCKER
ABSENCE SEIZURES SODIUM VALPROATE CALCIUM CHANNEL BLOCKER
LENNOUX GASTAUT SYNDROME SODIUM VALPROATE CALCIUM CHANNEL BLOCKER
DRAVET SYNDROME SODIUM VALPROATE CALCIUM CHANNEL BLOCKER
RAPID CYCLERS IN BIPOLAR DISORDER SODIUM VALPROATE CALCIUM CHANNEL BLOCKER
REFRACTORY INTRACTABLE RHEUMATIC CHOREA SODIUM VALPROATE CALCIUM CHANNEL BLOCKER
ABSENCE SEIZURES IN CHILDREN < 2 YRS ETHOSUXIMIDE CALCIUM CHANNEL BLOCKER
PARTIAL SEIZURE CARBAMAZEPINE SODIUM CHANNEL BLOCKER
ROLANDIC EPILEPSY CARBAMAZEPINE SODIUM CHANNEL BLOCKER
GLOSSOPHARYNGEAL NEURALGIA CARBAMAZEPINE SODIUM CHANNEL BLOCKER
TRIGEMINAL NEURALGIA (TIC DOLOUREX) CARBAMAZEPINE SODIUM CHANNEL BLOCKER

Compiled by
Dr. Bhargav Shreeram G.
 DRUGS OF CHOICE

JME IN PREGNANCY LAMOTRIGENE SODIUM CHANNEL BLOCKER

INFANTILE SPASMS WITH TUBEROUS SCLEROSIS VIGABATRIN GABA TRANSAMINASE BLOCKERS
INFANTILE SPASMS WITHOUT TUBEROUS SCLEROSIS ACTH > STEROIDS
FEBRILE SEIZURES p.r. DIAZEPAM BENZODIAZEPINES
STATUS EPILEPTICUS i.v. LORAZEPAM BENZODIAZEPINES
STATUS EPILEPTICUS IN PREGNANCY THIOPENTONE SODIUM BARBITURATES
ALCOHOL WITHDRAWAL CHLORDIAZEPOXIDE BENZODIAZEPINES
ALCOHOL DEPENDENCE CHLORDIAZEPOXIDE BENZODIAZEPINES
HICCUPS CHLORPROMAZINE PHENOTHIAZINE
CATATONIA LORAZEPAM BENZODIAZEPINES
JET LAG ZOLEPLON Z COMPOUNDS
INSOMNIA (SLEEP INDUCTION) ZOLEPLON Z COMPOUNDS
INSOMNIA (SLEEP MAINTENANCE) ESZOPICLONE Z COMPOUNDS
NEONATAL SEIZURES PHENOBARBITOL BARBITURATES
CRIGLER NAJJAR SYNDROME PHENOBARBITOL BARBITURATES
POST OPERATIVE CHILLS MEPERIDINE / PETHIDINE OPIOD AGONISTS
BENZODIAZEPINE / Z COMPOUND TOXICITY FLUMAZENIL
OPIOD TOXICITY NALOXONE OPIOD ANTAGONIST
OPIOD DEPENDANCE (RELAPSE PREVENTION) NALTREXONE OPIOD ANTAGONIST
MANIA PROPHYLAXIS LITHIUM
BIPOLAR DISEASE PROPHYLAXIS LITHIUM
HYPNIC HEADACHE LITHIUM
LITHIUM INDUCED DIABETES INSIPIDUS AMILORIDE EPITHELIAL SODIUM CHANNEL BLOCKER
CENTRAL DIABETES INSIPIDUS DESMOPRESSIN VASOPRESSIN ANALOGUE
NOCTURNAL ENURESIS DESMOPRESSIN VASOPRESSIN ANALOGUE
SIADH REDUCE FREE WATER INTAKE > TOLVAPTAN SELECTIVE V2 RECEPTOR BLOCKER
NEUROPATHIC PAIN AMITRIPTYLINE TRICYCLIC ANTI DEPRESSANT
POST HERPETIC NEURALGIA AMITRIPTYLINE TRICYCLIC ANTI DEPRESSANT
DEPRESSION FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR
PRE MENSTRUAL SYNDROME FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR
OBSESSIVE COMPULSIVE DISORDER FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR
PHOBIAS FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR
POST TRAUMATIC STRESS DISORDER FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR

Compiled by
Dr. Bhargav Shreeram G.
 DRUGS OF CHOICE

SOCIAL ANXIETY FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR

GENERALIZED ANXIETY DISORDER FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR
BULIMIA NERVOSA FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR
ANOREXIA NERVOSA FLUOXETINE SELECTIVE SEROTONIN REUPTAKE INHIBITOR
DEPRESSION WITH INSOMNIA MIRTAZAPINE NOR ADRENERGIC & SERATONERGIC
ALZHEIMERS DISEASE RIVASTIGMINE/GALANTAMINE CHOLINERGICS
SEVERE ALZHEIMERS DISEASE DONEPEZIL CHOLINERGICS
PARKINSON'S DISEASE LEVODOPA DOPAMINE PRECURSOR
PARKINSON'S - NON SEVERE / NON INTERFERING SELEGILINE MAO-B INHIBITORS
PARKINSON'S - SEVERE / INTERFERING (<65 YRS) PRAMIPEXOLE DOPAMINE AGONIST
PARKINSON'S - SEVERE / INTERFERING (>65 YRS) LEVODOPA DOPAMINE PRECURSOR
PARKINSONS DISEASE - ON PERIOD - PROLONGATION ENTECAPONE COMT INHIBITORS
PARKINSONS DISEASE - OFF PERIOD - RESCUE APOMORPHINE
DRUG INDUCED PARKINSONS DISEASE TRIHEXYPHENIDYL (BENZHEXOL) ANTI MUSCARINIC
HYPERPROLACTINEMIA CABERGOLINE DOPAMINE AGONIST
HYPERPROLACTINEMIA IN PREGNANCY BROMOCRIPTINE DOPAMINE AGONIST
HYPERPROLACTINEMIA IN INFERTILITY / OBESITY BROMOCRIPTINE DOPAMINE AGONIST
RESTLESS LEG SYNDROME ROPINIROLE DOPAMINE AGONIST
ACUTE DYSTONIA BENZTROPINE ANTI MUSCARINIC
AKATHISIA PROPRANOLOL β BLOCKER
NEUROLEPTIC MALIGNANT SYNDROME DANTROLENE
RESISTANT SCHIZOPHRENIA CLOZAPINE ATYPICAL ANTIPSYCHOTICS
SUICIDAL TENDENCY ECT > CLOZAPINE ATYPICAL ANTIPSYCHOTICS
SCHIZOPHRENIA ARIPIPRAZOLE ATYPICAL ANTIPSYCHOTICS
ACUTE ATTACK OF MANIA ARIPIPRAZOLE ATYPICAL ANTIPSYCHOTICS
MANIA IN PREGNANCY ARIPIPRAZOLE ATYPICAL ANTIPSYCHOTICS
LEVODOPA INDUCED PSYCHOSIS QUETIAPINE ATYPICAL ANTIPSYCHOTICS
RELAPSING REMITTING MULTIPLE SCLEROSIS INTERFERON β
PROGRESSIVE RELAPSING MULTIPLE SCLEROSIS MITOXANTRONE
ACUTE ATTACK OF MULTIPLE SCLEROSIS METHYL PREDNISOLONE CORTICOSTEROIDS
BELL'S PALSY PREDNISOLONE CORTICOSTEROIDS

Compiled by
Dr. Bhargav Shreeram G.
 DRUGS OF CHOICE

RESPIRATORY SYSTEM
ACUTE ATTACK OF BRONCHIAL ASTHMA LOW DOSE FLUTICASONE + FORMOTEROL ICS + LABA
COPD TIOTROPIUM/UMECLIDINIUM ANTI MUSCARINIC
PERSISTENT BRONCHIAL ASTHMA FLUTICASONE + FORMOTEROL ICS + LABA
LONGTERM FOR EXERCISE INDUCED ASTHMA FLUTICASONE INHALATIONAL CORTICOSTEROIDS
PULMONARY HYPERTENSION STAGE II/III BOSENTAN ENDOTHELIN ANTAGONIST
PULMONARY HYPERTENSION STAGE IV EPOPROSTERENOL PGI2 ANALOGUE
RECURRENT APNEA OF PREMATURITY CAFFEINE METHYLXANTHINES
ALLERGIC BRONCHOPULMONARY ASPERGILLOSIS (ABPA) PREDNISOLONE CORTICOSTEROIDS
PROLIFERATIVE BRONCHIOLITIS PREDNISOLONE CORTICOSTEROIDS
CRYPTOGENIC ORGANIZING PNEUMONIA /
PREDNISOLONE CORTICOSTEROIDS
BRONCHIOLITIS OBLITERANS ORGANISING PNEUMONIA
EOSINOPHILIC PNEUMONIA PREDNISOLONE CORTICOSTEROIDS
SARCOIDOSIS PREDNISOLONE CORTICOSTEROIDS

HEMATOLOGY
ANEMIA d/t CHEMOTHERAPY ERYTHROPOIETIN ANALOGUE
ANEMIA d/t CHRONIC RENAL FAILURE ERYTHROPOIETIN ANALOGUE
ANEMIA d/t ZIDOVUDINE ERYTHROPOIETIN ANALOGUE
ANEMIA d/t DIALYSIS ERYTHROPOIETIN ANALOGUE
NEUTROPENIA d/t CHEMOTHERAPY FILGRASTIM GRANULOCYTE - CSF
NEUTROPENIA d/t HIV FILGRASTIM GRANULOCYTE - CSF
THROMBOPROPHYLAXIS IN NON VALVULAR ATRIAL
DABIGATRAN + EDOXABAN DIRECT ORAL ANTICOAGULANTS
FIBRILLATION
THROMBOPROPHYLAXIS AFTER ELECTIVE HIP/KNEE
RIVAROXABAN FACTOR Xa INHIBITOR
ARTHROPLASTY
HEPARIN INDUCED THROMBOCYTOPENIA ARGATROBAN DIRECT THROMBIN INHIBITOR
CATHETER INDUCED THROMBOSIS UNFRACTIONATED HEPARIN INDIRECT THROMBIN INHIBITOR
THROMBOSIS IN CARDIOPULMONARY BYPASS UNFRACTIONATED HEPARIN INDIRECT THROMBIN INHIBITOR
CONCURRENT THROMBOLYSIS WITH INCREASED RISK OF
UNFRACTIONATED HEPARIN INDIRECT THROMBIN INHIBITOR
BLEEDING
THROMBOSIS IN MI LMWH / FONDAPARINAUX INDIRECT THROMBIN INHIBITOR

Compiled by
Dr. Bhargav Shreeram G.
 DRUGS OF CHOICE

THROMBOSIS IN UNSTABLE ANGINA LMWH / FONDAPARINAUX INDIRECT THROMBIN INHIBITOR

DEEP VEIN THROMBOSIS LMWH / FONDAPARINAUX INDIRECT THROMBIN INHIBITOR
PULMONARY EMBOLISM LMWH / FONDAPARINAUX INDIRECT THROMBIN INHIBITOR
CANCER INDUCED THROMBOSIS LMWH / FONDAPARINAUX INDIRECT THROMBIN INHIBITOR
PROPHYLAXIS OF THROMBOSIS IN VALVULAR ATRIAL
WARFARIN
FIBRILLATION
PROPHYLAXIS OF DEEP VENOUS THROMBOSIS WARFARIN
PROPHYLAXIS OF PULMONARY EMBOLISM WARFARIN
PROPHYLAXIS OF THROMBOSIS d/t MECHANICAL VALVE
WARFARIN
DURING PREGNANCY
ANTI PHOSPHOLIPID ANTIBODY SYNDROME WARFARIN
ANTI PHOSPHOLIPID ANTIBODY SYNDROME IN PREGNANCY ASPIRIN + (LMWH> UFH)

THROMBOLYSIS INDUCED BLEEDING € AMINO CAPROIC ACID

GASTROINTESTINAL SYSTEM
PEPTIC ULCER DISEASE OMEPRAZOLE PROTON PUMP INHIBITIOR
NSAID INDUCED ULCER OMEPRAZOLE PROTON PUMP INHIBITIOR
STRESS ULCER OMEPRAZOLE PROTON PUMP INHIBITIOR
GERD OMEPRAZOLE PROTON PUMP INHIBITIOR
ZOLLINGER ELLISON SYNDROME OMEPRAZOLE PROTON PUMP INHIBITIOR
H.PYLORI ULCER OMEPRAZOLE PROTON PUMP INHIBITIOR
GERD IN PREGNANCY/ CHILDREN ANTACIDS
PROPHYLAXIS OF ASPIRATION PNEUMONIA IN POST OP PTS RANITIDINE H2 BLOCKERS
CHEMOTHERAPY INDUCED NAUSEA & VOMITING - EARLY
ONDANSETRON 5HT3 RECEPTOR BLOCKERS
ONSET
CHEMOTHERAPY INDUCED NAUSEA & VOMITING - LATE ONSET APREPITANT NK1 RECEPTOR ANTAGONISTS
IBS WITH CONSTIPATION POLYETHYLENE GLYCOL
IBS WITH VISCERAL PAIN TRICYCLIC ANTIDEPRESSANTS
IBS WITH DIARRHOEA LOPERAMIDE OPIOD AGONISTS

Compiled by
Dr. Bhargav Shreeram G.
 DRUGS OF CHOICE

NON SECRETORY DIARRHOEA LOPERAMIDE OPIOD AGONISTS

ULCERATIVE COLITIS - MILD / MODERATE MESALAMINE 5 ASA ANALOGUE
ULCERATIVE COLITIS - SEVERE BUDESONIDE CORTICOSTEROIDS
ULCERATIVE COLITIS - STEROID DEPENDANT AZATHIOPRINE PURINE SYNTHESIS INHIBITORS
ULCERATIVE COLITIS - STEROID RESISTANT CYCLOSPORINE CALCINEURIN INHIBITORS
PROPHYLAXIS OF ULCERATIVE COLITIS MESALAMINE 5 ASA ANALOGUE
CROHN'S DISEASE - MILD / MODERATE PREDNISOLONE CORTICOSTEROIDS
CROHN'S DISEASE - SEVERE (WITH FISTULA) INFLIXIMAB ANTI TNF-α
PROPHYLAXIS OF CROHN'S DISEASE INFLIXIMAB ANTI TNF-α
HEMOCHROMATOSIS DEFEROXAMINE IRON CHELATOR

RENAL SYSTEM
NEPHROTIC SYNDROME GLUCOCORTICOIDS STEROIDS
STEROID DEPENDANT NEPHROTIC SYNDROME CYCLOPHOSPHAMIDE NITROGEN MUSTARDS
STEROID RESISTANT NEPHROTIC SYNDROME CYCLOSPORINE CALCINEURIN INHIBITORS
LUPUS NEPHRITIS CYCLOPHOSPHAMIDE + GLUCORTICOIDS NITROGEN MUSTARDS + STEROIDS
CYSTINURIA TIOPRONIN + POTASSIUM CITRATE CYSTEINE BINDER + URINE ALKALINIZER

ANTIMICROBIALS
MRSA (STAPHYLOCOCCAL ENDOCARDITIS) VANCOMYCIN GLYCOPEPTIDE ANTIBIOTICS
PSEUDOMEMBRANOUS ENTEROCOLITIS VANCOMYCIN GLYCOPEPTIDE ANTIBIOTICS
PNEUMOCOCCAL MENINGITIS VANCOMYCIN GLYCOPEPTIDE ANTIBIOTICS
ENTEROCOCCUS FAECIUM VANCOMYCIN GLYCOPEPTIDE ANTIBIOTICS
ENTEROCOCCUS FAECALIS AMPICILLIN AMINOPENICILLINS
AMPICILLIN RESISTANT ENTEROCOCCUS FAECALIS VANCOMYCIN GLYCOPEPTIDE ANTIBIOTICS
LISTERIA AMPICILLIN AMINOPENICILLINS
HEMOPHILUS INFLUENZAE - PNEUMONIA/OTITIS MEDIA AMPICILLIN AMINOPENICILLINS
STREPTOCOCCAL ENDOCARDITIS AMPICILLIN AMINOPENICILLINS
ENTEROCOCCAL ENDOCARDITIS AMPICILLIN AMINOPENICILLINS
VRSA DAPTOMYCIN LIPOPEPTIDES
EMPERICAL MRSA DAPTOMYCIN LIPOPEPTIDES
SYPHILIS - ALL STAGES BENZATHINE PENICILLIN G NARROW SPECTRUM PENICILLINS

Compiled by
Dr. Bhargav Shreeram G.
 DRUGS OF CHOICE

SYPHILIS - CNS STAGES AQUEOUS PENICILLIN G NARROW SPECTRUM PENICILLINS

STREPTOCOCCUS PENICILLIN G NARROW SPECTRUM PENICILLINS
YAWS PENICILLIN G NARROW SPECTRUM PENICILLINS
ACTINOMYCOSIS PENICILLIN G NARROW SPECTRUM PENICILLINS
LEPTOSPIROSIS PENICILLIN G NARROW SPECTRUM PENICILLINS
GAS GANGRENE PENICILLIN G NARROW SPECTRUM PENICILLINS
RAT BITE FEVER PENICILLIN G NARROW SPECTRUM PENICILLINS
MASTITIS CLOXACILLIN PENICILLINASE RESISTANT PENICILLINS
SURGICAL PROPHYLAXIS CEPHAZOLIN 1st GENERATION CEPHALOSPORINS
GONORRHOEA CEFTRIAXONE + AZITHROMYCIN 3rd GENERATION CEPHALOSPORINS
CEFTRIAXONE RESISTANT GONORRHOEA SPECTINOMYCIN AMINOGLYCOSIDES
E. COLI CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS
KLEBSIELLA CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS
PROVIDENCIA CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS
EMPIRICAL OSTEOMYELITIS CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS
EMPERICAL MENINGITIS CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS
HEMOPHILUS INFLUENZA MENINGITIS CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS
MENINGOCOCCAL MENINGITIS CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS
TYPHOID CEFTRIAXONE 3rd GENERATION CEPHALOSPORINS
TYPHOID (ORAL DOC) CEFIXIME 3rd GENERATION CEPHALOSPORINS
PSEUDOMONAS CEFTAZIDIME 3rd GENERATION CEPHALOSPORINS
MELIOIDOSIS / BURKHOLDERIA CEFTAZIDIME 3rd GENERATION CEPHALOSPORINS
FEBRILE NEUTROPENIA CEFTAZIDIME 3rd GENERATION CEPHALOSPORINS
ESBL PRODUCING ORGANISMS IMIPENEM CARBAPENEMS
SERRATIA IMIPENEM CARBAPENEMS
ENTEROBACTER IMIPENEM CARBAPENEMS
ACINETOBACTER IMIPENEM CARBAPENEMS
VRSA PNEUMONIA LINEZOLID OXAZOLIDINONE
VRE LINEZOLID OXAZOLIDINONE
MYCOPLASMA HOMINIS - STD DOXYCYCLINE TETRACYCLINES
UREAPLASMA - STD DOXYCYCLINE TETRACYCLINES
PROPHYLAXIS OF PLAGUE DOXYCYCLINE TETRACYCLINES
RICKETTSIA DOXYCYCLINE TETRACYCLINES

Compiled by
Dr. Bhargav Shreeram G.
 DRUGS OF CHOICE

BRUCELLA DOXYCYCLINE TETRACYCLINES

BORELLIA DOXYCYCLINE TETRACYCLINES
CHLAMYDIA (LGV) DOXYCYCLINE TETRACYCLINES
CHOLERA DOXYCYCLINE TETRACYCLINES
BARTONELLA DOXYCYCLINE TETRACYCLINES
PLEURODESIS DOXYCYCLINE TETRACYCLINES
PERICARDIODESIS DOXYCYCLINE TETRACYCLINES
PLAGUE GENTAMICIN AMINOGLYCOSIDES
TULAREMIA GENTAMICIN AMINOGLYCOSIDES
GUT STERILIZATION IN HEPATIC ENCEPHALOPATHY RIFAMIXIN
DIPHTHERIA ERYTHROMYCIN MACROLIDES
PERTUSSIS ERYTHROMYCIN MACROLIDES
PROPHYLAXIS OF RHEUMATIC FEVER IN PENICILLIN ALLERGY ERYTHROMYCIN MACROLIDES
ATYPICAL PNEUMONIA
AZITHROMYCIN MACROLIDES
(MYCOPLASMA, CHLAMYDIA, LEGIONELLA)
CAMPYLOBACTER AZITHROMYCIN MACROLIDES
CHANCROID AZITHROMYCIN MACROLIDES
CHLAMYDIA AZITHROMYCIN MACROLIDES
GRANULOMA INGUINALE AZITHROMYCIN MACROLIDES
CHOLERA IN PREGNANCY / CHILDREN AZITHROMYCIN MACROLIDES
TOXIC SHOCK SYNDROME CLINDAMYCIN + VANCOMYCIN
ANAEROBIC INFECTION - SUPRADIAPHRAGMATIC
CLINDAMYCIN LINCOSAMIDE ANTIBIOTICS
(PREVOTELLA)
STAPHYLOCOCCUS NASAL CARRIER Topical MUPIROCIN
SHIGELLA CIPROFLOXACIN FLUOROQUINOLONES
TRAVELLER'S DIARRHOEA CIPROFLOXACIN FLUOROQUINOLONES
PYELONEPHRITIS CIPROFLOXACIN FLUOROQUINOLONES
MENINGOCOCCAL CONTACTS / MASS PROPHYLAXIS CIPROFLOXACIN FLUOROQUINOLONES
ANTHRAX CIPROFLOXACIN FLUOROQUINOLONES
TYPHOID CARRIERS CIPROFLOXACIN FLUOROQUINOLONES
PNEUMOCYSTIS COTRIMOXAZOLE SULFONAMIDES
PROPHYLAXIS OF PNEUMOCYSTIS COTRIMOXAZOLE SULFONAMIDES

Compiled by
Dr. Bhargav Shreeram G.
 DRUGS OF CHOICE

NOCARDIOSIS COTRIMOXAZOLE SULFONAMIDES

ISOSPORIASIS COTRIMOXAZOLE SULFONAMIDES
CYCLOSPORIASIS COTRIMOXAZOLE SULFONAMIDES
SARCOCYSTOSIS COTRIMOXAZOLE SULFONAMIDES
CYSTITIS COTRIMOXAZOLE SULFONAMIDES
PROSTATITIS COTRIMOXAZOLE SULFONAMIDES
TOXOPLASMA SULFADIAZINE + PYRIMETHAMINE SULFONAMIDES
TOXOPLASMA IN PREGNANCY SPIRAMYCIN MACROLIDES
BURNS PATIENT TOPICAL SULFADIAZINE SULFONAMIDES
PROPHYLAXIS OF TB (PT WITH HIV WITH LATENT INFECTION) ISONIAZID
ISONIAZID INDUCED SEIZURES PYRIDOXINE
DERMATITIS HERPETIFORMIS DAPSONE
HERPES SIMPLEX VIRUS VALACYCLOVIR > ACYCLOVIR GUANINE ANALOGUES
VARICELLA ZOSTER VIRUS VALACYCLOVIR > ACYCLOVIR GUANINE ANALOGUES
CYTOMEGALOVIRUS VALAGANCYCLOVIR > GANCYCLOVIR GUANINE ANALOGUES
RECURRENT LARYNGEAL PAPILLOMATOSIS CIDOFOVIR CYTIDINE ANALOGUES
RESISTANT HERPES FOSCARNET
GENITAL WARTS (HPV) - MALE PODOPHYLLIN TOXIN MICROTUBULE INHIBITOR
GENITAL WARTS (HPV) - NON PREGNANT FEMALE IMIQUIMOD TLR-7 AGONIST
GENITAL WARTS (HPV) - PREGNANT FEMALE CRYOTHERAPY WITH LIQUID N2 (-196)
INFLUENZA - A, B OSELTAMIVIR NEURAMINIDASE INHIBITORS
BIRD FLU OSELTAMIVIR NEURAMINIDASE INHIBITORS
OSELTAMIVIR RESISTANT INFLUENZA A / B / BIRD FLU ZANAMIVIR NEURAMINIDASE INHIBITORS
HEPATITIS - B TENOFOVIR DNA POLYMERASE INHIBITORS
HEPATITIS B WITH HEPATITIS D SUPERINFECTION INTERFERON α
RESPIRATORY SYNCITIAL VIRUS INHALATIONAL RIBAVIRIN
PROPHYLAXIS OF RSV s.c. PALIVIZUMAB
HIV - PERINATAL TRANSMISSION NEVIRAPINE
MUCORMYCOSIS AMPHOTERICIN B POLYENES ANTIFUNGALS
SYSTEMIC FUNGAL INFECTIONS AMPHOTERICIN B POLYENES ANTIFUNGALS
KALA AZAR AMPHOTERICIN B POLYENES ANTIFUNGALS
PRIMARY AMOEBIC MENINGOENCEPHALITIS AMPHOTERICIN B POLYENES ANTIFUNGALS

Compiled by
Dr. Bhargav Shreeram G.
 DRUGS OF CHOICE

CRYPTOCOCCAL MENINGITIS i.v. AMPHOTERICIN B + i.v. FLUCYTOSINE POLYENES ANTIFUNGALS

CANDIDA ALBICANS FLUCONAZOLE AZOLES
COCCIDIAL MENINGITIS FLUCONAZOLE AZOLES
ENDEMIC MYCOSIS ITRACONAZOLE AZOLES
SPOROTRICHOSIS ITRACONAZOLE AZOLES
TINEA CRURIS ITRACONAZOLE AZOLES
TINEA CORPORIS ITRACONAZOLE AZOLES
INVASIVE ASPERGILLOSIS VORICONAZOLE AZOLES
SCEDOSPORIUM VORICONAZOLE AZOLES
TRICHOSPORIUM VORICONAZOLE AZOLES
PROPHYLAXIS OF INVASIVE ASPERGILLOSIS POSACONAZOLE AZOLES
PROPHYLAXIS OF FUNGAL INFECTION IN GVHD POSACONAZOLE AZOLES
CANDIDA GLABRATA CASPOFUNGIN ECHINOCANDINS
CANDIDA KRUSEI CASPOFUNGIN ECHINOCANDINS
CANDIDA PARAPSILOSIS CASPOFUNGIN ECHINOCANDINS
TRICHOPHYTON TERBINAFINE
MICROSPORUM GRISEOFULVIN
EPIDERMOPHYTON GRISEOFULVIN
T. CAPITIS (KERION/BOGGY SWELLING) GRISEOFULVIN
FUNGAL CORNEAL ULCER TOPICAL NATAMYCIN
ECHINOCOCCUS GRANULARIS ALBENDAZOLE BENZIMIDAZOLES
ECHINOCOCCUS MULTILOCULARIS ALBENDAZOLE BENZIMIDAZOLES
NEUROCYSTICERCOSIS ALBENDAZOLE BENZIMIDAZOLES
LIVER FLUKE TRICLOBENDAZOLE BENZIMIDAZOLES
HOOK WORM ALBENDAZOLE BENZIMIDAZOLES
ROUND WORM ALBENDAZOLE BENZIMIDAZOLES
WHIP WORM ALBENDAZOLE BENZIMIDAZOLES
TRICHINELLA SPIRALIS ALBENDAZOLE BENZIMIDAZOLES
ENTEROBIUS VERMICURALIS ALBENDAZOLE BENZIMIDAZOLES
THREAD WORM (STRONGYLOIDES) IVERMECTIN
ONCHOCERCA VOLVULUS IVERMECTIN
SCABIES (ORAL) IVERMECTIN
SCABIES Topical PERMETHRIN

Compiled by
Dr. Bhargav Shreeram G.
 DRUGS OF CHOICE

FILARIASIS DIETHYL CARBAMAZINE

LOA LOA DIETHYL CARBAMAZINE
DIPHYLLOBOTHRIUM LATUM PRAZIQUANTEL
HYMENOLEPIS NANA PRAZIQUANTEL
TAENIA SOLIUM (INTESTINAL) PRAZIQUANTEL
TAENIA SAGINATA PRAZIQUANTEL
LUNG FLUKE PRAZIQUANTEL
SCHISTOSOMA PRAZIQUANTEL
INTESTINAL AMOEBIASIS - ASYMPTOMATIC PARAMOMYCIN
INTESTINAL AMOEBIASIS - SYMPTOMATIC METRONIDAZOLE NITROIMIDAZOLE
EXTRAINTESTINAL AMOEBIASIS METRONIDAZOLE NITROIMIDAZOLE
TETANUS METRONIDAZOLE NITROIMIDAZOLE
GIARDIASIS METRONIDAZOLE NITROIMIDAZOLE
GARDNERELLA VAGINALIS METRONIDAZOLE NITROIMIDAZOLE
TRICHOMONIASIS METRONIDAZOLE NITROIMIDAZOLE
ANAEROBIC INFECTION - INFRADIAPHRAGMATIC
METRONIDAZOLE NITROIMIDAZOLE
(BACTEROIDES)
DRACUNCULIASIS METRONIDAZOLE NITROIMIDAZOLE
VISCERAL LEISHMANIASIS i.v. AMPHOTERICIN B POLYENES ANTIFUNGALS
VISCERAL LEISHMANIASIS (ORAL) MILTEFOSINE
CUTANEOUS LEISHMANIASIS SODIUM STIBOGLYCUNATE
TRYPANOSOMA - EARLY EAST AFRICAN SLEEPING SICKNESS SURAMINE
TRYPANOSOMA - LATE EAST AFRICAN SLEEPING SICKNESS MELARSOPROL
TRYPANOSOMA - EARLY WEST AFRICAN SLEEPING SICKNESS PENTAMIDINE
TRYPANOSOMA - LATE WEST AFRICAN SLEEPING SICKNESS EFLORNITHINE
TRYPANOSOMA - AMERICAN (CHAGA'S DISEASE) BENZNIDAZOLE
CRYPTOSPORIDIOSIS NITAZOXANIDE
RESISTANT GIARDIASIS NITAZOXANIDE
PLASMODIUM OVALE CHLOROQUINE + PRIMAQUINE
PLASMODIUM VIVAX CHLOROQUINE + PRIMAQUINE

Compiled by
Dr. Bhargav Shreeram G.
 DRUGS OF CHOICE

RADICAL CURE / TERMINAL PROPHYLAXIS OF RELAPSE OF

TAFENOQUINE > PRIMAQUINE
PLASMODIUM VIVAX/OVALE
ARTESUNATE + SULFADOXINE + PYRIMETHAMINE
PLASMODIUM FALCIPARUM
(+ PRIMAQUINE on Day 2)
ARTESUNATE + SULFADOXINE + PYRIMETHAMINE
CHOROQUINE RESISTANT P. OVALE/VIVAX
(+ PRIMAQUINE on Day 2)
MALARIA IN NORTH EASTERN STATES ARTEMETHER + LUMEFANTRINE
PLASMODIUM VIVAX IN PREGNANCY CHLOROQUINE
PLASMODIUM OVALE IN PREGNANCY CHLOROQUINE
SEVERE FALCIPARUM IN PREGNANCY QUININE
RESISTANT MALARIA IN PREGNANCY QUININE
PLASMODIUM FALCIPARUM IN PREGNANCY
QUININE + CLINDAMYCIN
(1st TRIMESTER)
PLASMODIUM FALCIPARUM IN PREGNANCY
ARTEMETHER + LUMEFANTRINE
(2nd & 3rd TRIMESTER)
MALARIA PROPHYLAXIS (FOR TRAVEL < 6 WKS) DOXYCYCLINE
MALARIA PROPHYLAXIS (FOR TRAVEL >6 WKS/ PREGNANCY) MEFLOQUINE
BABESIOSIS ATOVAQUONE + AZITHROMYCIN

ANTI CANCER DRUGS

WEGNER'S GRANULOMATOSIS CYCLOPHOSPHAMIDE NITROGEN MUSTARDS
CYCLOPHOSPHAMIDE INDUCED HEMORRHAGIC CYSTITIS MESNA
BRAIN TUMORS TEMOZOLOMIDE ALKYLATING AGENTS
HEAD & NECK CANCER CISPLATIN + 5FU PLATINUM COMPOUNDS
ESOPHAGEAL CANCER CISPLATIN + 5FU PLATINUM COMPOUNDS
GASTRIC CANCER CISPLATIN + 5FU PLATINUM COMPOUNDS
UROGENITAL CANCER CISPLATIN PLATINUM COMPOUNDS
ALK +VE NON SMALL CELL CARCINOMA LUNG CRIZONTINIB ALK INHIBITORS
MESOTHELIOMA PEMETREXED ANTI FOLATE DRUGS
PANCREATIC CA GEMCITABINE PYRIMIDINE ANALOGUES
HEPATOCELLULAR CARCINOMA SORAFENIB VEGF RECEPTOR INHIBITORS
GASTROINTESTINAL STROMAL TUMOUR IMATINIB TYROSINE KINASE INHIBITORS

Compiled by
Dr. Bhargav Shreeram G.
 DRUGS OF CHOICE

CHORIOCARCINOMA METHOTREXATE ANTI FOLATE DRUGS

CARCINOMATOUS MENINGITIS METHOTREXATE ANTI FOLATE DRUGS
RHEUMATOID ARTHRITIS METHOTREXATE ANTI FOLATE DRUGS
ERYTHRODERMIC PSORIASIS METHOTREXATE ANTI FOLATE DRUGS
PSORIATIC ARTHRITIS METHOTREXATE ANTI FOLATE DRUGS
CHRONIC PLAQUE PSORIASIS METHOTREXATE ANTI FOLATE DRUGS
MILD PSORIASIS ACITRETIN ORAL RETINOIDS
PSORIASIS IN HIV ACITRETIN ORAL RETINOIDS
PUSTULAR PSORIASIS ACITRETIN ORAL RETINOIDS
PUSTULAR PSORIASIS OF PREGNANCY
CYCLOSPORINE > ORAL STEROIDS CALCINEURIN INHIBITORS
(IMPETIGO HERPETIFORMIS)
TUMOR LYSIS SYNDROME ALLOPURINOL PURINE ANALOGUES
CML IMATINIB TYROSINE KINASE INHIBITORS
MULTI TYROSINE KINASE RESISTANT CML OMACETAXINE
HAIRY CELL LEUKEMIA CLADRIBINE PURINE ANALOGUES
HISTIOCYTOSIS CLADRIBINE PURINE ANALOGUES
MYELODYSPLASIA AZACITIDINE + DECITABINE PYRIMIDINE ANALOGUES
MYELODYSPLASIA WITH 5q DELETION LENALIDOMIDE THALIDOMIDE DERIVATIVE
ESSENTIAL THROMBOCYTHEMIA HYDROXYUREA
SICKLE CELL ANAEMIA HYDROXYUREA
POLYCYTHEMIA VERA ANAGRELIDE > HYDROXYUREA
PROMYELOCYTIC LEUKEMIA (PML) RETINOIC ACID
RETINOIC ACID RESISTANT PML ARSENIC TRIOXIDE
HER 2 POSITIVE BREAST CANCER TRANZTUZUMAB / PERTUZUMAB
HER 2 POSITIVE GASTRIC CANCER TRANZTUZUMAB / PERTUZUMAB
RESISTANT HER 2 POSITIVE BREAST CANCER / GASTRIC CANCER LAPATINIB / NERATINIB
RENAL CELL CANCER BEVACIZUMAB / SUNITINIB

Compiled by
Dr. Bhargav Shreeram G.