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    Cover Letter For Journal

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    Navneet Chaudhary
    This letter summarizes a research manuscript submitted to the Journal of Material Advances. The manuscript describes an electrochemical immunosensor using a nanostructured lanthanum oxide and reduced graphene oxide composite interface for low detection of ciprofloxacin antibiotic in milk samples. The composite was characterized using various spectroscopic and microscopic techniques. It showed effective and selective determination of ciprofloxacin in a broad linear range with low detection limits. The immunosensor also demonstrated good selectivity and was applied to real milk samples. The composite material has potential for detection of other antibiotic compounds. The author requests peer review and publication of the original research in the journal.

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    Cover Letter For Journal

    Uploaded by

    Navneet Chaudhary
    12 views2 pages
    This letter summarizes a research manuscript submitted to the Journal of Material Advances. The manuscript describes an electrochemical immunosensor using a nanostructured lanthanum oxide and reduced graphene oxide composite interface for low detection of ciprofloxacin antibiotic in milk samples. The composite was characterized using various spectroscopic and microscopic techniques. It showed effective and selective determination of ciprofloxacin in a broad linear range with low detection limits. The immunosensor also demonstrated good selectivity and was applied to real milk samples. The composite material has potential for detection of other antibiotic compounds. The author requests peer review and publication of the original research in the journal.

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    cover latter for journal

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    Cover Letter for Journal

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    This letter summarizes a research manuscript submitted to the Journal of Material Advances. The manuscript describes an electrochemical immunosensor using a nanostructured lanthanum oxide and reduced graphene oxide composite interface for low detection of ciprofloxacin antibiotic in milk samples. The composite was characterized using various spectroscopic and microscopic techniques. It showed effective and selective determination of ciprofloxacin in a broad linear range with low detection limits. The immunosensor also demonstrated good selectivity and was applied to real milk samples. The composite material has potential for detection of other antibiotic compounds. The author requests peer review and publication of the original research in the journal.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    12 views2 pages

    Cover Letter For Journal

    Uploaded by

    Navneet Chaudhary
    This letter summarizes a research manuscript submitted to the Journal of Material Advances. The manuscript describes an electrochemical immunosensor using a nanostructured lanthanum oxide and reduced graphene oxide composite interface for low detection of ciprofloxacin antibiotic in milk samples. The composite was characterized using various spectroscopic and microscopic techniques. It showed effective and selective determination of ciprofloxacin in a broad linear range with low detection limits. The immunosensor also demonstrated good selectivity and was applied to real milk samples. The composite material has potential for detection of other antibiotic compounds. The author requests peer review and publication of the original research in the journal.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 2

    Jawaharlal Nehru University

    Special Centre for Nanoscience


    New Delhi -110067, India

    Dr. Pratima R. Solanki Dated: 16th August 2023


    Assistant Professor

    To
    The Editor,
    Journal of Material Advances

    Dear Editor
    Please find an attached soft copy of an original research manuscript titled " Electrochemical
    Immunosensor based on Nanostructured Lanthanum oxide substituted reduced graphene oxide
    Interface for Ultralow Ciprofloxacin Detection in Milk Samples " by Navneet Chaudhary, Amit K.
    Yadav, Damini Verma, Jai Gopal Sharma, Pratima R. Solanki to your esteemed journal “ Journal of
    Material Advances" for subsequent publication.
    This is a transfer manuscript from the Journal of Material Chemistry B. Editor Professor Håkan
    Engqvist has suggested us transfer our manuscript to Materials Advances, for which he is also an
    editor. He also said that if we transfer this manuscript, the manuscript will be sent for peer review
    and will be eligible for a full APC waiver.
    Here, we aim to fabricate an electrochemical immunosensor based on nanostructured lanthanum
    oxide nanoparticles decorated with reduced graphene oxide nanocomposite (nLa2O3 NPs@rGO) for
    sensitive and selective determination of trace amounts of ciprofloxacin (CPX) antibiotic in milk
    samples. These, nLa2O3@rGO composites were functionalized by APTES and were deposited
    electrophoretically on the surface of the ITO glass substrate followed by immobilizing anti-CPX
    antibodies covalently via EDC-NHS chemistry. The morphological, structural, and electrochemical
    characterization of nLa2O3 NPs@rGO and other developed immunoelectrodes were done through
    spectroscopic (contact angle, FT-IR, Raman, XRD); microscopic (SEM, TEM) and electrochemical
    (CV, DPV, and EIS) tools. Here, rGO's large surface area assists in enhancing the nLa 2O3 NPs
    dispersibility that provides synergistic effects to the nLa2O3 NPs@rGO nanocomposite which leads
    to electron transfer process acceleration. Hence, the developed immunoelectrode
    (BSA/anti-CPX/APTES/nLa2O3 NPs@rGO/ITO) effectively determines CPX having a broad linear
    detection range from 10-6 to 600 µg mL-1 with a lower detection limit of 0.055 µg mL -1 and good
    durability of 25 days. Furthermore, the immunosensor showed good selectivity towards CPX and
    was used in real samples of processed milk. Thus, nLa2O3 NPs@rGO composite could rise as
    emerging as a potential material for other antibiotics determination also.

    I certify that this manuscript, or any part of it, has not been published and will not be submitted
    elsewhere for publication while being considered by the “Journal of Material Advances”. We are
    looking forward to receiving the referee's reports in the near future.

    With Best Regards

    Yours Sincerely

    Pratima R. Solanki
    E-mail: [email protected]; [email protected], Tel:+9111-26704740

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