Dr.

Xin Zhao (orcid: 0000-0002-9521-7768)

E-mail: [email protected]; Tel: +852 3400 8083
Address: Department of Biomedical Engineering, The Hong Kong Polytechnic University,
Hung Hom, Hong Kong
Profile: an enthusiastic and highly motivated biomaterial scientist with multi-disciplinary
research experience, skilled laboratory techniques and teaching and editorial experience

Research Interests: biomaterials, tissue engineering, drug delivery, cell micro-environment,

microfluidics

Strengths
 Broad knowledge and specialized techniques in biomaterials, tissue engineering, drug delivery,
cell micro-environment and microfluidics
 Excellent communication and organization skills developed via writing papers and grant proposals,
presenting at international conferences, demonstrating experiments, lecturing and editing scientific
publications
 Fluent English, Cantonese and Mandarin
 International study and work experience in China, UK and USA

Higher Education
2006-2010 PhD in Biomaterials and Tissue Engineering, University College London (UCL,
ranked 22nd in the world by US News 2016), UK
2005-2006 MSc with Distinction in Engineering and Physical Science in Medicine (top 5%, GPA
72.5/100), Imperial College London (ranked 18th in the world by US News 2016),
UK
2001-2005 B. Eng First Class (Hons) in Bioengineering (top 1%, GPA 3.821/5.0), South China
Normal University (SCNU, ranked 57th from 1056 universities in China in 2015), China
Additional MBA (certificate), London Business School (ranked 2nd Business School in the
2007-2008 world by the Financial Times in 2015), UK
Understanding Entrepreneurial Opportunities and New Venture Development

Work Experience
2016 - Assistant professor, Department of Biomedical Engineering, The Hong Kong
Polytechnic University, Hong Kong, China
2015-2016 Associate professor, School of Life Science and Technology, Xi’an Jiaotong
University, China (ranked 17th among 1056 universities in China)
2014-2015 Postdoctoral research fellow, Harvard John A. Paulson School of Engineering and
Applied Sciences (ranked 1st in the world by US News 2016), USA
2012-2014 Postdoctoral research fellow, Harvard-MIT Health Sciences and Technology,
Harvard Medical School (ranked 1st in the world by US News 2016), USA
2011-2012 Research associate, Guangzhou iGenomics Co., Ltd., China

Honors and Awards:

1. Dorothy Hodgkins Postgraduate Award, £ 90,000, EPSRC, UK, 2006
2. Central Research Fund, £ 2,000, University of London, UK, 2009
3. Outstanding Young Scholars, ¥ 1,500,000, Xi’an Jiaotong University, China, 2015

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 4. International Federation of Medical and Biological Engineering (IFMBE) Asia Pacific
Research Networking (APRN) Fellowship, HK representative, 2018
5. General Participant of Max Planck Croucher Symposium 2019 (theme ‘Matter to Life’), (only
two are selected from one university in Hong Kong), Okinawa, 2019
6. Supervised undergraduate student Miss Panyang Tanyaporn to receive the Top 40 projects
FYP+ Funding Scheme 2019;
7. Supervised undergraduate student Miss Panyang Tanyaporn to attract the Proof-of-Concept
Funding from PolyU;
8. Supervised PhD student Mr Zhang Qiang to win the NanoMed 2019 Best Poster Award in the
3rd International Symposium on Translational Nanomedicine
9. Supervised student Miss Panyang Tanyaporn, Mr Lam Chun Hei, Mr Ho Pan Bei and Mr Hung
Chi Hin won the third price of the 2019 Hong Kong University Student Innovation and
Entrepreneurship Competition.
10. Nomination of “Nature Research Awards for Inspiring Science” 2019 (Shortlisted 10
from >150 applications globally).
11. Merit awards (Individual Award, only 3 from 155 faculty members) of Faculty Awards for Outstanding
Performance/Achievement 2018/19.
12. Supervised student Mr Ho Pan Bei attract the Travel Grants for Winter School on Tissue
Engineering and Regenerative Medicine 2020
13. Supervised student Mr Qiang Zhang win the Top Prize of Hong Kong Medical and Healthcare
Device Industries Association Student Research Award (HKMHDIA, HK$2,500, only two in
PolyU) 2019
14. PolyU UG Summer Research Abroad Sponsorship (USRA-2016, HK$36,750), 2020
15. Supervised student Mr Ho Pan Bei won the Best Teaching Assistant Award, 2020
16. Supervised student Mr Ho Pan Bei, Mr Yuhe Yang and Mr Qiang Zhang won PolyU Micro Fund
(HK$ 120,000), 2020

Teaching Experience
2016- Subject 1: Biomaterials Science and Engineering; Subject 2: Bionanotechnology;
Subject 3: Wearable Healthcare and Fitness Devices for Everyone, Subject 4: Skin-
care Technologies, The Hong Kong Polytechnic University, Hong Kong SAR, China
2012-2015 Laboratory demonstration for undergraduate, MSc and PhD students in Biomaterials
and Tissue Engineering, Harvard University, USA
2006-2009 Laboratory demonstration for undergraduate and MSc students in Biomaterials and
Tissue Engineering, UCL, UK

Editorships
2020 Editor of a book by Wiley titled "Biofabrication for Orthopedics”
2020 Editorial board of “Journal of the Mechanical Behavior of Biomedical Materials”
2020 Guest editor of special issue “Biomaterials for Engineering Cellular Environments in Tissue
Engineering” of Frontiers in Bioengineering and Biotechnology

2019 Founding Editor-in-chief of “Engineered Regeneration” by KeAi Communications Co

2019 Associate editor of “Biointerface Research in Applied Chemistry”
2019 Guest editor of “Procedia CIRP of BioManufacturing Conference 2019”
2019 Editorial board of “Advances in Mechanical Engineering”
2018 Guest editor of special issue “Graphene Nanocomposites” of Molecules
2017 Guest editor of special issue “Polymer Scaffolds for Biomedical Applications” of Polymers

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 2017 Editorial board of “Frontiers in Molecular Biosciences, Bioengineering and Biotechnology
and Materials”
2017 Editor of a book by Elsevier titled "Theranostic Bionanomaterials"
2016 Guest editor of special issue “Therapeutic Nanomaterials” of Drug Discovery Today
2015 Guest editor of special issue “Biomaterials for Plastic and Aesthetic Surgery” of Plastic
and Aesthetic Research

Grants
1. Innovation and Technology Fund, (PI, Grant no. ITS/065/19, HK$ 1,369,650), Spatiotemporal
dual delivery of therapeutic gas and biomolecule for prevention of stent thrombosis and restenosis,
01/05/2020- 31/10/2022.
2. General Research Fund, Research Grants Council (PI, Grant no. 15202119, HK$ 495,000),
Dual-targeting, bioresponsive and programmed site-specific drug delivery for pancreatic cancer
treatment, 01/2020-09/2022
3. Health and Medical Research Fund (PI, Grant no. 06173186, HK$ 947,400), Development of
bioresponsive nano-peptide-gel fibrous membranes for an on-demand siRNA delivery for
prevention of tendon adhesions: a preclinical study, 24/09/2019-23/09/2021
4. Early Career Scheme, Research Grants Council, (PI, Grant no. 25208218, HK$ 750,000),
Long-term drug release from electrospun fibrous scaffolds for prevention of hypertrophic scar,
01/01/2019-31/12/2021
5. Germany/Hong Kong Joint Research Scheme (Ref. No. G-PolyU508/18), Research Grants
Council, (PI, HK$ 89,600). Development of soft and elastic hydrogel nanofibrous scaffolds for
rapid vascularized skin regeneration. 01/01/2019-31/12/2020
6. Inter-Departmental Open Project of State Key Laboratory of Ultra-precision Machining
Technology (SKL-UPMT), (PI, Grant no. P0033576, HK$ 380,000), Study of neural stem cellular
behaviors on high throughput precision etching facilitated microcurvatures, 13/10/2020-
12/04/2022.
7. Teaching Development Grant (TDG) 2019-22 (Ref: SS-BME1), (PI, HK$ 199,800), Towards a
new age of course-based undergraduate research training: apprenticeship via e-platform for lab
equipment management and teaching, 01/07/2020- 31/12/2021.
8. Greata Group Co. Ltd., China, (PI, ¥ 1,500,000): Complementary and synergistic signal
molecules loaded electrospun fibers for tendon healing, 01/09/2018-31/08/2021.
9. Youth Projects of National Science Foundation of China (PI, Grant no. 11702233, ¥ 250,000),
Development of soft and elastic hydrogel-based 3D microenvironment for neuronal differentiation
of neural stem cells, 01/01/2018-31/12/2020.
10. Intra-Faculty Interdisciplinary Projects, Research Funding Scheme, (PI, HK $400,000),
Bioresponsive Nanoparticle Drug Delivery Systems for Pancreatic Cancer Treatment, 15/5/2019-
14/5/2020
11. Visiting Scholarship Scheme of the K.C. Wong Education Foundation (PI, HK$ 20,000),
01/01/2020-31/12/2020
12. PolyU, (PI, Grant No. 1-ZE7S, HK$ 500,000), Long-term drug release from electrospun fibrous
scaffolds for prevention of hypertrophic scar, 2017-2020.
13. PolyU, (PI, Grant No. G-YBWS, HK$ 105,000), Treatment of hypertrophic scars using electrospun
fibrous scaffolds with long-term drug release properties, 2017-2019.
14. PolyU, (PI, HK$ 150,000), International Capstone Project of Development of a Novel Hairy
Hydroxyapatite Strengthened Hydrogel Membrane as Artificial Periosteum, 9/2018-3/2019.
15. State Key Laboratory of Molecular Engineering of Polymers (Fudan University), (PI, Grant No.

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 K2019-20, HK$ 35,000), Adhesion microenvironment triggered drug release from electrospun
fibers for tendon adhesion prevention, 1/1/2019-1/11/2020
16. Guangdong provincial key laboratory of functional soft condensed matter, (PI, Grant No.
HK$ 23,000), Construction of microfluidic-3D bioprinter platform based on photocrosslinkable
hydrogel material, 1/10/2018-1/9/2020
17. Central Research Fund (CRF), PI, £ 2,000, University of London, UK, 2009.
18. Innovation and Technology Fund, (Co-I, HK$ 1,577,851), Development of cooling mask,
18/03/2019-17/03/2021
19. General Research Fund, Research Grants Council, (Co-I, HK$ 632,421), A hybrid nanosystem
for photo-treatment of Alzheimer’s disease in a blood-brain barrier on-a-chip, 01/01/2019-
31/12/2021
20. PolyU, (Co-I, Grant No. 1-YW3E, HK$ 754,936), A hybrid two-dimensional nanomaterials based
nanosystem for near-infrared light phototherapy, 2018-2020.
21. Shenzhen Science and Technology Innovation Committee (Co-I, Grant no. 20170248,
¥ 2,000,000), Study on the mechanism of mechanical factors affecting the tumor development
and metastasis of hepatoma stem cells, 01/09/2017-31/08/2020.
22. Science and Technology Department of Sichuan Province, Photothermal nanocrystals for tumor
antigens capturing and tumor immunotherapy (Co-I, Grant no. 20GJHZ0244, ¥ 200,000),
01/01/2020-31/12/2022
Total grant support as PI (~HK$ 6,969,650) and as co-I (~HK$ 5,677,000).

Conference Presentations and Invited Talks

1. 15th International Conference on Plasma Based Ion Implantation & Deposition (session chair),
Shenzhen, Dec 2019
2. 4th CIRP Conference on BioManufacturing, (Organizing Committee), Guangzhou, Dec 2019.
3. 2019 Annual Conference for Society of Chinese Mechanical Engineering Biomanufacturing
Division and the International Symposium on Bio-Manufacturing (ACBD-ISBM2019), (invited talk),
Beijing, 2019
4. Max Planck Croucher Symposium 2019, (only 2 are selected form one institute in Hong Kong)
Okinawa, Nov 2019
5. 3D Bioprinting Submit (keynote speech), Beijing, China, 2019
6. Suzhou Sports Medicine Annual Conference (keynote speech), Suzhou, China, 2019
7. The 5th Youth Forum on Additive Manufacturing (keynote speech), Nanjing, China, 2019
8. Third International Symposium on Translational Nanomedicine (invited talk), Guangzhou, China,
2019
9. The 12th IEEE International Conference on Nano/Molecular Medicine and Engineering (session
chair), Hawaii, USA，2018
10. The 3rd Asian University Symposium on Biomedical Engineering (keynote speech), Seoul, Korea,
2018
11. The 4th Youth Forum on Additive Manufacturing (keynote speech), 2018
12. World Congress on Medial Physics and Biomedical Engineering (invited talk), Prague, Czech
Republic, 2018
13. The 2nd Karolinska Institutet Symposium “Reparative Medicine and Beyond" (invited talk), 2018
14. The 6th International Symposium on Surface and Interface of Biomaterials (keynote speech,
session chair), 2017
15. Biomaterials for regenerative medicine (invited talk by Prof Liming Bian). Chinese University of
Hong Kong, Hong Kong, 2017.
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16. Photocrosslinkable gelatin for tissue engineering, International Soft Matter Symposium & the 6th
“China Soft Matter Day” (invited talk), Shen Zhen, China, 2017
17. The 8th WACBE World Congress on Bioengineering (session chair, organizing committee), HK,
China), HK, China
18. Photocrosslinkable gelatin for tissue engineering, Karolinska Institutet Symposium “Reparative
Medicine and Beyond (invited talk), Hong Kong, China, 2017
19. Biomaterials for regenerative medicine (invited talk by Anderson Shum). University of Hong Kong,
Hong Kong, 2017.
20. Biomaterials for translational medicine. 3D bioprinting and biomaterials (keynote speech), Hong
Kong, China, 2016.
21. Stem cell-laden photo-crosslinkable microspheres for bone regeneration, Tissue Engineering and
Regenerative Medicine International Society- Asia Pacific Meeting (invited talk), Taiwan, China,
2016
22. Stem cell-laden photo-crosslinkable microspheres for bone regeneration, 6th International
Conference on Optofluidics (invited talk), Beijing, China, 2016
23. Stem cell-laden photo-crosslinkable microspheres for bone regeneration, 10th World Biomaterials
Congress (oral presentation), Montreal, Canada, 2016
24. Micro- and nanofabrication of biomaterials and their biomedical applications, the 2nd National
Young Scholar’s Forum on Additive Manufacturing (invited talk), Xi’an, China, 2016
25. Biomaterials for translational medicine (invited talk). City University of Hong Kong, Hong Kong,
2016.
26. Tumor triggered cancer therapy (invited talk). International Young Scholars Forum, Shanghai
Jiaotong University, China, 2015.
27. Biomaterials for translational medicine (invited talk). Xi’an Jiaotong University, China, 2015.
28. Cell behavior on injectable and biodegradable polymers, the 22nd European Biomaterials
Conference, Switzerland, 2009.
29. Injectable degradable reactive calcium phosphate contained composites for bone repair and drug
delivery, the 22nd European Biomaterials Conference, Switzerland, 2009.
30. Injectable degradable polymeric adhesives containing reactive calcium phosphate filler particles,
the Pan European Federation of the International Association for Dental Research, UK, 2008.
31. Injectable biodegradable reactive calcium phosphate loaded composites for combined bone
repair and drug delivery, the 8th World Biomaterials Congress, the Netherlands, 2008.
32. Injectable biodegradable poly (ester-co-ether) methacrylate monomers for bone tissue
engineering and drug delivery applications, the 17th Interdisciplinary Research Conference on
Biomaterials, UK, 2007.

List of Publications
A. Published journal papers
2020
1. Yang YH, Zhang Q, Xu TP, Zhang HY, Zhang M, Lu L, Hao YF#, Fuh JYH#, Zhao X#
Photocrosslinkable nanocomposite ink for printing strong, biodegradable and bioactive bone
graft. Biomaterials (IF 10.317). 2020 (accepted)
2. Chen ZY, Zhang Q, Li HM, Wei Q, Zhao X#, Chen FL#, Elastin-like polypeptide modified silk
fibroin porous scaffold promotes osteochondral repair. Bioactive Materials (IF 9.8). 2020
(accepted)
3. Zhao X#, Zhu DH#. Editorial. Engineered Regeneration. 2020,1,34.
4. Yang ZL#, Zhao X#, Hao R, Tu Q, Tian X, Xiao Y, Xiong K, Wang M, Feng Y, Huang N, Pan G.
Bio-clickable and mussel adhesive peptide mimics for engineering vascular stent surfaces. P
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 Natl Acad Sci USA (IF 9.412). 2020 (accepted). Doi: 10.1073/pnas.200373117
5. Mao M, Bei HP, Lam CH, Chen P, Wang S, Chen Y, He J, Zhao X*, Human-on-leaf-chip: A
biomimetic vascular system integrated with chamber-specific organs, Small (IF 11.459, journal
cover). 2020. Doi: 2020 Apr 24:2000546.
6. Tu QF, Zhao X#, Liu S, Li XY, Zhang Q, Yu H, Xiong KX, Huang N, Yang ZL, Spatiotemporal
dual-delivery of therapeutic gas and growth factor for prevention of vascular stent thrombosis
and restenosis, Appl. Mater. Today (IF 8.352). 2020. Doi: 10.1016/j.apmt.2019.100546
7. Pan BH, Zhang Q, Lam CH, Yuen HY, Kuang S, Zhao X*. Petite miracles: insight into the nano-
management of scarless wound healing. Drug Discov Today (IF 7.321). 2020. Doi:
10.1016/j.drudis.2020.03.013
8. Rao J, Pan Bei H, Yang Y, Liu Y, Lin H, Zhao X*. Nitric oxide producing cardiovascular stent
coatings for prevention of thrombosis and restenosis. Front Bioeng Biotech (IF 3.644), 2020;
8,578.
9. Chen H, Sun T, Yan Y, Ji X, Sun Y, Zhao X, Qi J, Cui WG, Deng, Zhang HY, Cartilage matrix-
inspired biomimetic superlubricated nanospheres for treatment of osteoarthritis, Biomaterials
(IF 10.317), 2020,242,119931.DOI: 10.1016/j.biomaterials.2020.119931
10. He W, Wang Z, Hou C, Huang X, Yi B, Yang Y, Zheng W, Zhao X, Yao X, Mucus-inspired
supramolecular adhesives with oil-regulated molecular configurations and long-lasting
antibacterial properties. ACS Appl Mater Interfaces (IF 8.758),2020,12(14),16877-86.
11. Zhang YC, Hu JL, Xie RQ, Yang YH, Cao J, Tu YH, Zhang Y, Qin T, Zhao X., A programmable,
fast-fixing, osteo-regenerative, biomechanically robust bone screw, Acta Biomaterialia (IF
7.242), 2020,103,293-305.
12. Gao H, Kam C, Chou TY, Wu MY, Zhao X, Chen S. A simple yet effective AIE-based
fluorescent nano-thermometer for temperature mapping in living cells using fluorescence
lifetime imaging microscopy. Nanoscale Horiz (IF 9.927, journal cover), 2020, 5, 488-494.
13. Yang Y, Gao P, Wang J, Tu Q, Bai L, Xiong K, Qiu H, Zhao X, Maitz MF, Wang H, Li X, Zhao
Q, Xiao Y, Huang N, Yang Z, Endothelium-mimicking multifunctional coating modified
cardiovascular stents via a stepwise metal-catechol-(amine) surface engineering strategy,
Research, 2020 ,9203906. Doi:10.34133/2020/9203906
14. Yang T, Du Z, Qiu H, Gao P, Zhao X, Wang H, Tu Q, Xiong K, Huang N, Yang Z, From surface
to bulk modification: Plasma polymerization of amine-bearing coating by synergic strategy of
biomolecule grafting and nitric oxide loading, Bioact Mater (IF 8.724), 2020, 5(1),17-25.

2019
15. Zhu, Z., Liu, J, Liu, C., Wu, X., Li, Q., Chen, S., Zhao X*., Weitz, D. A., Microfluidics-assisted
assembly of injectable photonic hydrogels toward reflective cooling. Small (IF 11.459) 2019,
1903939. Doi:10.1002/smll.201903939
16. Zhang F, Zhang Q, Li XY, Huang N, Zhao X*, Yang ZL. Mussel-inspired dopamine-CuII coatings
for sustained in situ generation of nitric oxide for prevention of stent thrombosis and restenosis.
Biomaterials (IF 10.317), 2019, 194,117-129.
17. Wu, D., Yu, Y., Zhao, C., Shou, X., Piao, Y., Zhao X*., Wang, S. (2019). NK Cell-encapsulated
porous microspheres via microfluidic electrospray for tumor immunotherapy. ACS Appl Mater
Interfaces (IF 8.758), 2019, 37,33716-33724.
18. Yildirimer L, Zhang Q, Kuang S, Cheung CW, Chu, K, He Y, Yang M, Zhao X*, Engineering
three-dimensional microenvironments towards in vitro disease models of the central nervous
system. Biofabrication (IF 8.213), 2019, 11(3),032003.
19. Ji X, Yan Y, Sun T, Zhang Q, Wang Y, Zhang M, Zhang H, Zhao X*, Glucosamine sulphate-

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 loaded distearoyl phosphocholine liposomes for osteoarthritis treatment: combination of
sustained drug release and improved lubrication. Biomater Sci (IF 6.183), 2019,7,2716-2728.
20. Bei HP, Yang YH, Zhang Qiang, Tian Y, Luo XM, Yang M*, Zhao X*, Graphene-based
nanocomposites for neural tissue engineering, Molecules (IF 3.267), 2019, 24(4),658.
21. Zhao X*, Yang M. Graphene Nanocomposites, Molecules (IF 3.267), 2019, 24,2440.
22. Lv, S, Nie, J; Gao, Q; Xie, C; Zhou L; Qiu, J, Fu, J; Zhao X; He, Yong, Micro/nanofabrication
of brittle hydrogels using 3D printed soft ultrafine fiber molds for damage-free demolding.
Biofabrication (IF 8.213), 2019,12(2),025015.
23. Chen ZK, Luo XH, Zhao X, Yang M, Wen CY, Label-free cell sorting strategies via biophysical
and biochemical gradients, J Orthop Translat (IF 3.986), 2019,17,55-63.
24. Zhang YC, Hu JL, Zhao X, Xie Q, Qin T, Ji FL. Mechanically robust shape memory
polyurethane nanocomposites for minimally invasive bone repair. ACS Applied Bio Materials,
2019, 2(3),1056-1065.
25. Wang J, Fan Y, Tan Y, Zhao X, Zhang Y, Cheng C, Yang M. Porphyrinic Metal-Organic
Framework PCN-224 Nanoparticles for Near-Infrared-Induced Attenuation of Aggregation and
Neurotoxicity of Alzheimer’s Amyloid-β Peptide. ACS Appl Mater Interfaces (IF 8.758),
2018,10(43),36615-36621.

2018
26. Yang ZL, Yang Y, Zhang L, Xiong KQ, Li XY, Zhang F, Wang J, Zhao X*, Huang N. Mussel-
inspired catalytic selenocystamine-dopamine coatings for long-term generation of therapeutic
gas on cardiovascular stents. Biomaterials (IF 10.317) ,2018, 178,1-10.
27. Chen H, Cheng R, Zhao X#, Zhang Y, Allison T, Yan Y, Shen HK, Zhang Y, Qi J, Feng Y, Liu
L, Pan G, Cui W, Deng L. An injectable self-healing coordinative hydrogel with antibacterial and
angiogenic properties for diabetic skin wound repair. NPG Asia Mater (IF 8.131, journal cover),
2019, 11(1), 3.
28. Zhang L, Bei PH, Piao Y, Wang YF, Yang M, Zhao X*. Polymer brush-grafted mesoporous
silica nanoparticles for triggered drug delivery, ChemPhysChem (IF 3.144), 2018,19(16),1956-
1964.
29. Zhang Q, Sito L, Mao M, He J, Zhang YS, Zhao X*. Current advances in skin-on-a-chip models
for drug testing. Microphysiol Syst,2018, 2,4.
30. Zhang J, Zhao X, Liang L, Li J, U Demirci U, Wang SQ. A decade of progress in liver
regenerative medicine. Biomaterials (IF 10.317), 2018,157,161-176
31. Yan Y, Sun T, Zhang H, Ji X, Sun Y, Zhao X, Deng L, Qi J, Cui W, Santos HA, Zhang H.
Euryale ferox seed-inspired superlubricated nanoparticles for treatment of osteoarthritis. Adv
Func Mater (IF 16.836), 2018,29(4),1807559.
32. Liu L, Tian XH, Ma Y, Duan YQ, Zhao X, Pan GQ. A versatile mussel-inspired dynamic
biointerface: from specific cell behavior modulation to selective cell isolation. Angewandte
Chemie (IF 12.959) ,2018, 57(26),7878-7882.
33. Wang Y, Cui, WG, Zhao X, Wen SZ, Sun YL, Han JM, Zhang HY. Bone remodeling-inspired
dual delivery electrospun nanofibers for promoting bone regeneration. Nanoscale (IF 6.895)
,2018,11(1),60-71.
34. Lu S, Cuzzucoli F, Jiang J, Liang LG, Wang Y, Kong MQ, Zhao X, Cui W, Li J, Wang S.
Development of a biomimetic liver tumor-on-a-chip model based on decellularized liver matrix
for toxicity testing. Lab on a Chip (IF 6.774), 2018, 18(22),3379-3392.
35. Yang Z, Tu Q, Shen X, Liu Y, Zhang Q, Zhao X, Maitz M, Liu T, Qiu H, Wang J, Huang N, A
facile metal-phenolic-amine strategy for dual-functionalization of blood-contacting devices with

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 antibacterial and anticoagulant properties, Mater Chem Front (IF 6.788), 2019,3(2),265-275.
(Hot article in December 2018)
36. Wang J, Fan Y, Lee HW, Yi C, Cheng C, Zhao X, Yang M. Ultrasmall metal-organic framework
Zn-MOF-74 nanodots: Size-controlled synthesis and application for highly selective colorimetric
sensing of Iron (III) in aqueous solution. ACS Appl Nano Mater, 2018,1(7),3747-3753.
37. Chang J, He JK, Mao M, Zhou WX, Lei Q, Li X, Li DC, Chua CK, Zhao X. Advanced material
strategies for next-generation additive manufacturing. Materials (IF 3.057), 2018,11(1),166.
38. Gao H, Zhao X, Chen S. AIEgen-based fluorescent nanomaterials: Fabrication and biological
applications. Molecules (IF 3.267), 2018,23(2),419.

2017
39. Zhao X, Sun XM, Yildirimer L, Lang Q, Zheng WY, Lin ZY, Zhang YG, Cui WG, Annabi N,
Khademhosseini A. Cell infiltrative hydrogel fibrous scaffolds for accelerated wound healing.
Acta Biomaterialia (IF 7.242), 2017, 49,66-77.
40. Sun XM, Lang Q, Zhang HB, Cheng LY, Zhang Y, Guoqing Pan, Zhao X, Yang HL, Zhang YG,
Santos AH, Cui WG. Electrospun photocrosslinkable hydrogel fibrous scaffolds for rapid in vivo
vascularized skin flap regeneration, Adv Func Mater (IF 16.836), 2017, 27,1604617. (journal
cover)
41. Liu YL, Zhi X, Yang M, Zhang JP, Lin LN, Zhao X, Hou WX, Zhang CL, Zhang Q, Pan F, Alfranca
G, Yang YM, de la Fuente JM, Ni J, Cui DX. Tumor-triggered drug release from calcium
carbonate-encapsulated gold nanostars for near-infrared photodynamic/photothermal
combination antitumor therapy, Theranostics (IF 8.579), 2017, 7,1650-1662.
42. Dong YQ, Jin GR, Ji CC, He RY, Lin M, Zhao X, Li A, Lu TJ, Xu F. Non-invasive tracking of
hydrogel degradation using upconversion nanoparticles, Acta Biomaterialia (IF 7.242), 2017,
55,410-419.
43. Zhao S, Su W, Shah V, Hobson D, Yildirimer L, Yeung KWK, Zhao JZ, Cui W, Zhao X*.
Biomaterials based strategies for rotator cuff repair. Colloid Surface B (IF 4.389),
2017,157,407-416.
44. Zhang Q, Li YQ, Lin ZY, Wong KY, Lin M, Yildirimer L, Zhao X*. Electrospun polymeric
micro/nanofibrous scaffolds for long-term drug release and their biomedical applications, Drug
Discov Today (IF 7.321), 2017, 22,1351-1366. (Top 25% cited of the journal in 2018)
45. Jin GR, Zhao X, Feng X. Therapeutic nanomaterials for cancer therapy and tissue regeneration.
Drug Discov Today (IF 7.321), 2017, 22,1285-1287
46. Huang GY, Li F, Zhao X, Ma YF, Li YH, Jin GR, Genin G, Lu TJ, Xu F. Functional and biomimetic
materials for engineering of the three-dimensional cell microenvironment. Chem Rev (IF 52.758),
2017, 117 (20),12764–12850 (ESI highly cited paper).
47. Zhang, J., Zhao, X., Liang, L., Li, J., Demirci, U., & Wang, S. (2018). A decade of progress in
liver regenerative medicine. Biomaterials (IF 10.317), 2017,157,161-176.
48. Zhao H, Ding RH, Zhao X, Li YW, Qu LL, Pei H, Yildirimer L, Wu ZW, Zhang WX. Graphene-
based nanomaterials for drug and/or gene delivery, bioimaging, and tissue engineering. Drug
Discov Today (IF 7.321), 2017, 22(9),1302-1317.
49. Liu XL, Gao P, Du J, Zhao X, Wong KKY. Long-term anti-inflammatory efficacy in intestinal
anastomosis in mice using silver nanoparticle-coated suture. J Pediatr Surg, 2017, 52(12),2083-
2087.
50. Hu Y, Hong Y, Shi NY, Huang GY, Zhao X*. Construction and regulation of three-dimensional
microenvironment for neural stem cells based on methylacrylate gelatin. China Sciencepaper,
2017,12(24), 2770-2776.

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2016
51. Zhao X, Liu S, Yildirimer L, Zhao H, Ding RH, Wang HN, Cui WG, Weitz D. Injectable stem cell
laden photo-crosslinkable microspheres fabricated using microfluidics for rapid generation of
osteogenic tissue constructs. Adv Func Mater (IF 16.836), 2016, 26, 2809-2819. (journal cover)
52. Zhao X, Lang Q, Yildirimer L, Lin ZY, Cui WG, Annabi N, Ng KW, Dokmeci MR, Ghaemmaghami
AM, Khademhosseini A. Photocrosslinkable gelatin hydrogel for epidermal tissue engineering.
Adv Healthc Mater (IF 7.367), 2016, 5,108-118. (most highly viewed publication of AHM of
2015).
53. Cheng LY, Sun XM, Zhao X#, Wang L, Yu J, Pan GQ, Li B, Yang H, Zhang YG, Cui WG. Surface
biofunctional drug-loaded electrospun fibrous scaffolds for comprehensive repairing
hypertrophic scars. Biomaterials (IF 10.317), 2016, 83, 169–181.
54. Zhao H, Lin ZY, Yildirimer L, Dhinakara A, Zhao X*, Jun Wu. Polymer-based nanoparticles for
protein delivery: design, strategy and applications. J Mater Chem B (IF 5.344), 2016,4, 4060-
4071.
55. Lang Q, Ren YK, Hobson D, Tao Y, Hou LK, Jia YK, Hu QM, Liu JW, Zhao X*, Jiang HY. In-
plane microvortices micromixer-based AC electrothermal for testing drug induced death of tumor
cells, Biomicrofluidics (IF 2.500), 2016, 10, 064102.
56. Lin ZY, Shah V, Dhinakar A, Yildirimer L, Cui WG, Zhao X*. Intradermal fillers for minimally
invasive treatment of facial aging. Plast Aesthet Res, 2016, 3, 72-82.
57. Ng K, Gao B, Yong KW, Li YH, Shi M, Zhao X, Li ZD, Pingguan-Murpy B, Xu F. Paper-based
cell culture platform and its emerging biomedical applications. Mater Today (IF 26.416), 2017,
20(1), 32-44.
58. Gao B, Yang QZ, Zhao X, Jin GR, Ma YF, Xu F. 4D bioprinting for biomedical applications.
Trends Biotechnol (IF 14.343), 2016, 158, 166-174. (journal cover, ESI highly cited paper).
59. Hou WX, Zhao X, Qian XQ, Pan F, Zhang CL, Yang YM, de la Fuente JM, Cui DX.. pH- sensitive
self-assembling nanoparticles for tumor near-infrared fluorescence imaging and chemo–
photodynamic combination therapy. Nanoscale (IF 6.895), 2016, 8, 104-116.
60. Rahim R, Ochoa M, Parupudi T, Zhao X, Dokmeci M, Khademhosseini A, Ziaie B. A low- cost
flexible pH sensor array for wound assessment. Sensors Actuat B-Chem (IF 7.100), 2016, 229,
609–617.
61. Chen H, Guo L, Wicks J, Ling C, Zhao X, Yan YF, Qi J, Cui W, Deng LF. Quickly promoting
angiogenesis by using a DFO-loaded photo-crosslinked gelatin hydrogel for diabetic skin
regeneration. J Mater Chem B (IF 5.344), 2016, 4, 3770-3781.
62. Zhang DD, Lin ZY, Cheng RY, Yu J, Zhao X, Chen XL, Cui WG. Reinforcement of transvaginal
repair using polypropylene mesh functionalized with basic fibroblast growth factor. Colloid
Surface B (IF 4.389), 2016, 142,10-19. (journal cover)
63. Sun XM, Zheng WY, Cheng LY, Zhao X, Jin R, Sun BS, Shi YM, Zhang L, Zhang Y, Zhang YG,
Cui WG. Two-dimensional electrospun nanofibrous membranes for promoting random skin flap
survival. RSC Advances (IF 3.119), 2016, 6, 9360-9369.
64. Lang Q, Ren YK, Wu YS, Guo YB, Zhao X, Tao Y, Liu JW, Zhao H, Lei l, Jiang HY.
Multifunctional resealable perfusion chip for cell culture and tissue engineering. RSC Advances
(IF 3.119), 2016, 27183-27190.
65. Cui WG, Zhao X, Zhang YG. Biomaterials for facial aging. Plast Aesthet Res, 2016, 3, 70-71

2015
66. Zhao X, Cui WG. Disease-triggered hydrogel therapy. Mater Today (IF 26.416), 2015, 18, 56-

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 57.
67. Zhao X, Jiang SC, Chen S, Zhou L, Lin ZY, Pan GQ, He F, Li B, Yang HL, Fan CY, Cui WG.
Optimization of intrinsic and extrinsic tendon healing through controllable water-soluble
mitomycin-C release from electrospun fibers by mediating adhesion-related gene expression.
Biomaterials (IF 10.317), 2015, 61, 61-74.
68. Zhao X, Yuan ZM, Yildirimer L, Zhao JW, Lin ZY, Pan GQ, Cui WG. Tumor-triggered controlled
drug release from electrospun fibers using inorganic caps for inhibiting cancer relapse. Small
(IF 11.459), 2015, 11, 4284-4291. (journal cover)
69. Zhao X, Zhao JW, Lin ZY, Chen XL, Zhu YQ, Cui WG. Self-coated interfacial layer at
organic/inorganic phase for temporally controlling dual-drug delivery from electrospun fibers.
Colloid Surfaces B (IF 4.389), 2015, 130, 1-9.
70. Zhao X, Hu CM, Pan GQ, Cui WG. Pomegranate-structured electrosprayed microspheres for
long-term controlled drug release. Part Part Syst Char (IF 3.099), 2015, 32, 529–535.
71. Zhao S, Zhao X#, Dong SK, Pan GQ, Zhang Y, Zhao JZ, Cui WG. A hierarchical, stretchable and
stiff fibrous biotemplate engineered using stagger-electrospinning for augmentation of rotator
cuff tendon-healing. J Mater Chem B (IF 5.344), 2015, 3, 990-1000. (journal cover)
72. Yuan ZM, Zhao X#, Zhao JW, Pan GQ, Qiu WW, Wang XH, Zheng Q, Cui WG. Synergistic
mediation of tumor signaling pathways in hepatocellular carcinoma therapy via dual- drug-loaded
pH responsive electrospun fibrous scaffolds. J Mater Chem B (IF 5.344), 2015, 3, 3436-3446.
(journal cover)
73. Sun XD, Zhao X*, Li Qing, D’Ortenzio M, Nguyen B, Xu X, Wen Y. Development of a hybrid
gelatin hydrogel platform for tissue engineering and protein delivery applications, J Mater Chem
B (IF 5.344), 2015, 3, 6368-6376.
74. Jiang LQ, Zhao X#, Zhao LL, Ni B, Qian H, Maclean JL, Zhu JB, Zhang Y, Ge L. The quantitative
detection of the uptake and intracellular fate of albumin nanoparticles. RSC Advances (IF
3.119), 2015, 5, 34956-34966.
75. Pan GQ, Liu S, Zhao X, Zhao JW, Fan CY, Cui WG. Full-course inhibition of biodegradation-
induced inflammation in fibrous scaffold by loading enzyme-sensitive prodrug. Biomaterials (IF
10.317), 2015, 53, 202-210.
76. Cheng YJ, Cheng H, Zhao X, He F, Xu XD. Self-assembled micelles of multi-functional
amphiphilic fusion (MFAF) peptide for targeted cancer therapy. Polym Chem (IF 5.342), 2015,
6, 3512-3520.

2014
77. Jiang SC, Zhao X#, Chen S, Pan GQ, Song JL, He N, Li FF, Cui WG, Fan CY. Down-regulating
ERK1/2 and SMAD2/3 phosphorylation by physical barrier of celecoxib-loaded electrospun
fibrous membranes prevents tendon adhesions. Biomaterials (IF 10.317), 2014, 35, 9920-9929.
78. Wu J, Zhao X#, Wu DQ, Chu CC. Development of a biocompatible and biodegradable hybrid
hydrogel platform for sustained release of ionic drugs. J Mater Chem B (IF 5.344), 2014, 2,
6660 – 6668.
79. Yuan ZM, Zhao X#, Wang XH, Qiu WW, Chen XL, Zheng Q, Cui WG. Promotion of initial anti-
tumor effect via polydopamine modified doxorubicin-loaded electrospun fibrous membranes. Int
J Clin Exp Patho (IF 0.252), 2014, 7, 5436 - 5449.
80. Hasan A, Paul A, Vrana NE, Zhao X, Memic A, Hwang Y, Dokmeci M, Khademhosseini A.
Microfluidic techniques for development of 3D vascularized tissue. Biomaterials (IF 10.317),
2014, 35, 7308-7325.
81. Zhao JW, Jiang SC, Zheng WY, Zhao X, Chen XL, Fan CY, Cui WG. Smart electrospun fibrous

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 scaffolds inhibit tumor cells and promote normal cell proliferation. RSC Advances (IF 3.119),
2014, 4, 51696-51702.
82. Chen S, Wang GD, Wu TY, Zhao X, Liu S, Li G, Cui WG, Fan CY. Silver nanoparticles/ibuprofen-
loaded poly(L-lactide) fibrous membrane: anti-infection and anti-adhesion effects. Int J Mol Sci
(IF 4.556), 2014, 15, 14014-14025.
83. Zhu YQ, Edmonds L, Zhao X, Chen XL, Hu CM, Cheng YS, Cui WG. In vitro and in vivo
evaluation of Rapamycin-eluting nanofibers coating on cardia stents. RSC Advances (IF 3.119),
2014,4, 34405-34411.

2011
84. Zhao X, Olsen I, Pratten J, Knowles JC, Young AM. Reactive calcium phosphate-containing
poly(ester-co-ether) methacrylate bone adhesives: setting, degradation and drug release
considerations. J Mater Sci-Mater M (IF 2.489), 2011, 22,1993- 2004.

2010
85. Zhao X, Olsen I, Li HY, Gellynck K, Buxton PG, Knowles JC, Salih V, Young AM. Reactive
calcium phosphate - containing poly (ester-co-ether) methacrylate bone adhesives: chemical,
mechanical and biological considerations. Acta Biomaterialia (IF 7.242), 2010, 6, 845-855.
86. Chrzanowski W, Abou Neel E, Armitage D, Zhao X, Knowles JC, Salih V. In vitro studies on the
influence of surface modification of Ni-Ti alloy on human bone cells. J Biomed Mater Res A (IF
3.525), 2010, 93, 1596 -1608.

2008
87. Abou Neel EA, Zhao X, Ho SM, Knowles JC, Salih V, Young AM. Injectable degradable
polymeric adhesives containing reactive calcium phosphate filler particles. J Dent Res (IF
4.914), 2008, 87, 1.

2004
88. Zhao X, Chen G. In vitro tissue culture and plantlet regeneration of the sensitive plant Mimosa
pudica L. Journal of South China Normal University (Natural Science Edition), 2004,12, 40-42.
# co-first author; * corresponding author.

B. Books
89. Wenguo Cui and Xin Zhao. Theranostic Bionanomaterials. Total: 21 Chapter. Elsevier. 2019.5.
ISBN: 9780128153413. Page Count: 526.

C. Book chapters
90. Yun Piao, Ho Pan Bei, Allison Tam, Yuhe Yang, Qiang Zhang, Mo Yang, Xin Zhao*. Calcium
Phosphate Nanoparticle-Based Systems for Therapeutic Delivery. In Theranostic
Bionanomaterials. Elsevier. Page 147-164. Editor. Wenguo Cui and Xin Zhao.
91. Zhao X, Yildirimer L, Lin ZY, Cui WG. ‘Bionanofibers in drug delivery’ in ‘Nanobiomaterials in
Drug Delivery’. Editor. Grumezescu AM. Elsevier. (2016) 403-446.
92. Yildirimer L, Hobson D, Lin ZY, Cui WG, Zhao X*. ‘Tissue- engineered human skin equivalents
and their applications in wound healing’ in ‘Tissue Engineering for Artificial Organs:
Regenerative Medicine, Smart Diagnostics and Personalized Medicine’. Editor. Hasan A. Wiley-
VCH.
93. Zhao X, Hobson D, Lin ZY, Cui WG. Electrospun biodegradable polyester micro/nano fibers for

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 drug delivery and their clinical applications. Editor. Majeti R. Pan Standford Publishing.
94. Wen HY, Li YY, Zhao X. ‘Redox-sensitive polymeric nanoparticles for intracellular drug delivery’
in ‘Biomedically Inspired Nanomaterials’. Editor. Shi Donglu. World Scientific Publishing. (2014)
21-48.
95. Zhao X, Selimović Š, Camci-Unal G, Dokmeci MR, Yildirimer L, Annabi N, Khademhosseini A.
‘Microfabrication of three-dimensional vascular structures’ in ‘Vascularization: Regenerative
Medicine and Tissue Engineering’. Editor. Brey Eric. CRC Press. (2013) 143-162.

D. Patents
1. Cui WG, Zhu YQ, Yuan TW, Cheng YS, Zhao X, Gao F, Degradable esophagus scaffolds
National utility model patent, China. (granted, 201520876939.4).
2. Ni Q, Wu W, Zhao X, Cui WG, Dai Y, Wan LP. NO releasing blood vessel scaffolds. National
utility model patent, China. (granted, 201610397559.1).
3. Yang ZL, Guo RQ, Huang N, Tu QF, Xiong KQ, Zhao X, A bimolecule thin film and preparation
method with regionally selective controllable immobilization (granted, 201910027335.5)
4. Zhao X, Yang YH, Preparation and application of periosteum mimicking nanocomposite
materials (filed, 201911080184.6)
5. Zhao X, Yang YH, A preparation method of photocrosslinkable nanocomposite and bone tissue
engineering scaffolds (filed, 201911078331.6)

Reviewer Experience:
ACS Nano, PNAS, Biomaterials, Small, Acta Biomater, Adv Healthc Mater, Drug Discov Today, Sci
Rep, ACS Biomater Sci Eng, Colloids Surf. B, Adv Mater Interfaces, Cellulose, Applied Materials
Today, etc.

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