0% found this document useful (0 votes)
26 views3 pages

GROUP 2 - Written Report - Journal Critique Using PICOTS Tool

Download as pdf or txt
Download as pdf or txt
Download as pdf or txt
You are on page 1/ 3

UNIVERSITY OF THE ASSUMPTION

Bachelor of Science in Pharmacy


Health Technology Assessment and Health Policy

GROUP 2:
DUNGCA, JUSTINE MARLWEN
CORALDE, ALEXINE AIRA
MIRANDA, NIKKA MARIEL
NAGUIT, MISSY ANGELINE
VALDEZ, STELLA MARRISE
VISDA, MARIEL

Perceptions of generic medication in the general population,


doctors and pharmacists: a systematic review

Introduction

Generic drugs have been available for many years and are frequently used to treat a wide
range of acute and chronic illnesses. A generic medicine must be bioequivalent to the originator
product in terms of strength, safety, and quality in order to be licensed for use. While generic
medicines may differ from their comparable branded medicines in terms of color, size, form, and
excipient chemicals, they must be able to demonstrate bioequivalence to the originator product in
terms of rate and extent of absorption. Generic formulations provide the same therapeutic efficacy
as branded medications but at a substantially lower cost. As a result, generic medicines have grown
in popularity as a way to relieve strain on drug budgets, and they now account for a growing
proportion of administered drugs.

Although the usage of generic drugs has increased, there is evidence that many doctors and
pharmacists have unfavorable attitudes toward generics and are hesitant about prescribing them.
Several doctors are opposed to brand substitution because they believe generic medications are
inferior to branded medications.

POPULATION
● Condition
To investigate negative perceptions about generic medicines and evaluate the
proportions of lay people, doctors and pharmacists who hold these perceptions.
In summary, the literature review shows that among the: general population,
doctors, and pharmacists have the most negative perception when it comes to generic
medication.

● Risk Factors
Since medical professionals have a significant impact on patients' decisions to take
generic medications, the negative attitudes of physicians and pharmacists are likely to be
the barriers to a wider acceptance of generics. In order to promote the acceptability of
generic prescribing and substitution, more research is required on treatments that can be
used by the public and by medical professionals to minimize negative perceptions regarding
efficacy, safety, and side effects.

● Demographics
The population consists of doctors, pharmacists, and laypeople which are
participants coming from various reviews publications.

INTERVENTION
● Technology Type
- The type of technology used to determine and examine the negative view of the
three population sample includes χ2 tests of contingency tables with a Yates
correction using GraphPad QuickCalcs software and Microsoft Excel 2010 software.

● Methods to collect data


- One author did the initial review of publications through the titles and available
abstracts for all identified citations to select relevant publications. Then the two
authors did a full review of selected articles whilst using an excel to record data such
as the country of origin and sample type (doctors, pharmacists, laypeople), sample
size and proportions of participants that have negative perceptions with generic
medicines.

COMPARATOR
- In the statistical analyses, they compared the negative perceptions of the three sample
groups to the total population or sample size using χ2 tests of contingency tables to come up
with actual numeric values to show the ratio of each population group that presents
negative perceptions toward generic medicines.
- This study also shows the percentages of the population group that have negative
perceptions compared to positive perceptions.

OUTCOMES
- The outcome of the study is that the effectiveness, safety and quality of generic drugs are
issues that concern a significant number of laypeople, doctors and Pharmacists.
- Since medical professionals have significant impact on a patient's decision to take the
generic medication, the negative attitudes of the doctors and pharmacist are likely to
constitute barriers to a wider acceptance of generic drugs
- Systematic search process identified 2737 potentially relevant publications. The initial
review eliminated 2582 of these publications, including duplicates, leaving 155 articles for
full-text review. Of these, 73 articles were put forward for quality assessment. During this
process, 21 studies were eliminated. The publication dates for these studies ranged from
1987 through 2015, and included data from 27 countries. Additional characteristics of the
studies included in the review are presented for the general population, and for doctors and
pharmacists.
- The outcome of this study showed that there are a significant number of people coming
from the three sample sizes that have negative perception towards generic medicines and
that is the focus of the study. The rough range of percentage was around mostly 20% to 35%
which shows that the remaining percentages are showing either neutral or positive
perceptions toward generic medicines.

TIMING
● Duration
- It was released on December 15th, 2015. MEDLINE, EMBASE, PsycINFO, and Scopus are all
part of the systematic search database. This was carried out on September 6, 2015, in order
to retrieve the pertinent peer-reviewed literature.

SETTING
- In the UK, there was strong opposition when plans were proposed to introduce generic
substitution into UK primary care

You might also like