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    Pharma Theory Reviewer

    Uploaded by

    Katherine Roque
    1. The document discusses various topics related to drug processing and administration including the routes of administration, factors affecting drug processing, categories of drugs during pregnancy, and treatments for various conditions. 2. Key drugs and their effects are mentioned like rifampicin causing red urine, isoniazid for tuberculosis, and thalidomide being category X and causing birth defects. 3. The stages of drug processing - absorption, distribution, metabolism and excretion - are summarized as well as factors influencing drug effects such as age, weight, sex, and psychological factors.

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    Pharma Theory Reviewer

    Uploaded by

    Katherine Roque
    20 views2 pages
    1. The document discusses various topics related to drug processing and administration including the routes of administration, factors affecting drug processing, categories of drugs during pregnancy, and treatments for various conditions. 2. Key drugs and their effects are mentioned like rifampicin causing red urine, isoniazid for tuberculosis, and thalidomide being category X and causing birth defects. 3. The stages of drug processing - absorption, distribution, metabolism and excretion - are summarized as well as factors influencing drug effects such as age, weight, sex, and psychological factors.

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    Pharma Theory Reviewer

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    1. The document discusses various topics related to drug processing and administration including the routes of administration, factors affecting drug processing, categories of drugs during pregnancy, and treatments for various conditions. 2. Key drugs and their effects are mentioned like rifampicin causing red urine, isoniazid for tuberculosis, and thalidomide being category X and causing birth defects. 3. The stages of drug processing - absorption, distribution, metabolism and excretion - are summarized as well as factors influencing drug effects such as age, weight, sex, and psychological factors.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    20 views2 pages

    Pharma Theory Reviewer

    Uploaded by

    Katherine Roque
    1. The document discusses various topics related to drug processing and administration including the routes of administration, factors affecting drug processing, categories of drugs during pregnancy, and treatments for various conditions. 2. Key drugs and their effects are mentioned like rifampicin causing red urine, isoniazid for tuberculosis, and thalidomide being category X and causing birth defects. 3. The stages of drug processing - absorption, distribution, metabolism and excretion - are summarized as well as factors influencing drug effects such as age, weight, sex, and psychological factors.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 2

    Processing of Drugs Medicine for TB

    1. Absorption a. Rifampicin- color of the urine is reddish


    2. Distribution- target the specific site b. Isoniazid
    3. Metabolism- liver c. Pyrazinamide
    4. Excretion- kidney d. Ethambutol- eye blindness
    e. Streptomycin- ototoxic

    Dosage
    1. Minimum- therapeutic Thalidomide- example of category X
    2. Maximum
    3. Toxic- sobra - For hyperemesis gravidarum
    4. Lethal- nakakamatay - Side effect: Amelia and phocomelia in
    5. Loading- ex: 300mg muna other words no limbs
    6. Maintenance- yung natirang 200mg
    Vit B12 (Cobalamin)- deficient for vegetarian
    7. Therapeutic
    Vitamin C or Ascorbic acid or Sodium ascorbate
    Vit. B9 (folic acid)- for mothers
    Category of drugs
    Penicillin- discovered by Alexander Flemming
    A- Proven safe both for mother and baby
    B- Tested for animals but not human
    C- Benefits outweighs the risk
    D- Benefits outweighs the risk Factors that affect the processing of drugs
    1. Age
    X- not safe, teratogenic 2. Weight
    3. Sex
    4. Psychological factor
    Route
    1. GI- Oral, Rectal, NGT
    K+ wasting- example: Furosemide (Lasix)
    2. Parenteral- Injection route
    - IV, ID (10-15), IM (90), SQ(45) K+ sparing- example: Spironolactone (Aldactone)
    - ID example: PPD (Purified Protein
    Derivative)
    - For TB patient Angiotensin Receptor Blocker (ARB): losartan
    - Skin test result after 48-72h
    - Delayed hypersensitivity reaction Odynophagia- pain when swallowing
    3. Inhalational
    4. Topical
    5. Drops *Note: Asthmatic patient is not allowed to take beta
    blockers

    Idiosyncratic- Unusual effect of drug


    Night blindness (Nyctalopia)
    Paradoxical- Opposite effect of drug
    - vit. A deficiency
    Hypersensitivity symptoms: -
    Erythema, Pruritus, dyspnea Vaginal Candidiasis
    Anaphylaxis- severe allergy - Caused by Candida albicans
    - Secretion is cottage cheese like
    - If not severe use Ketoconazole
    - If severe Amphotericin B
    Paracetamol – Generic name Mid-stream- urinalysis
    Biogesic- Brand name Hyperemesis Gravidarum – excessive bleeding
    - Drug indication is anti-antidiuretic *Note: Ice chips or cracker
    - analgesic - pain (every 6 hrs.)
    - Anti pyretic – fever (every 4hrs.) Viability – chance of survival – 24 weeks
    * Note: give the medication round the clock for 24
    37-41 weeks – normal birth
    hours even w/o S/S
    Omeprazole- drug classification is proton pumps LAM (Lactation amenorrhea method) – for family
    inhibitor (PPI) planning

    Syphilis- penicillin/penicillin G Menopause- complete cessation for 1 year

    Oral Thrush- nystatin Estrogen – bone density

    3 ways to check patency of NGT (Nasogastric Tube) Progesterone – hormone of pregnancy


    a. X-ray
    2hrs no Per Oral – after suka dahil sa inom- Deficiency of
    b. Stethoscope w/borborygmic sound
    Vit B1
    c. Check for the pH
    Dehydration – AIVE IV (Dextrose)
    7.35-7.45- Normal blood PH
    Vit B1 – B complex for sobrang lasing
    SL- sublingual (under the tongue)
    Hepatotoxic
    Nc- nasal cannula
    Ac (ante cibum)- before meal Lack of B9 and B12 – anemia
    Pc (post cibum)- after meal
    Prn- as needed Organogenesis (1st term)
    Stat- immediately NTD’s (Neural Tube Defects)
    NGT- nasogastric tube
    Anencephaly- usually sa mga umiinom na mother
    Largest muscle- Gluteus maximus - Spinabifida
    - Avoid sciatic nerve – near the anus/ nagkakaron
    ng paralysis kung eto ang natamaan Otic- for ears

    FAT SOLUBLE VITAMIN

    A. Vit A- pampalinaw ng mata


    *Note: Di binibigay sa buntis at planong
    magbuntis- it can harm the baby’s
    - O – origin
    development
    - I – insertion
    B. Vit D- bones
    - N – nerve (Inferior gluteal nerve)
    C. Vit E- Skin
    - A – action
    D. Vit K- for blood clotting
    ANTI HYPERTENSIVE MEDICATION
    A. Ace Inhibitor/ends in pril
    WATER SOLUBLE VITAMIN
    B. Beta Blockers (olol)
    C. Calcium Channel Blockers A. Vit C
    D. Diuretic- K+ (pump the heart) (3.5-4.5mE/) B. Vit B
    a. K+ wasting
    CNIV- SO
    b. K+ sparing
    *NOTE: K+ (pump the heart)
    Kcl (lethal injection)

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