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Warts
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 Dr. R.K. Manchanda, Deputy Director (Homoeopathy)

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 Deptt. of Medicine, Nehru Homoeopathic Medical College and Hospital.
Board of Homepathic System
of Medicine  Dr. Neena Mehan, Assistant Professor, Practice of Medicine, Deptt. of Medicine

Clinical Studies and  Dr. B.R.Sur Homoeopathic Medical College and Hospital.
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 Dr. Ritu Bahl, Homoeopathic Physician
Clinical Studies and
 Dr. Rajni Atey, Homoeopathic Physician
Publications

Introduction
Concept of Miasm

Wart is one of the common dermatological disorders caused by DNA viruses, which grow in the epidermis. The source of infection is
Warts
other infected individuals and the disease is transmitted by direct or close contact. It has very low infectivity; a casual contact with an
infected individual is unlikely to result in the disease. The virus enters into the skin through minor or microscopic injuries. Clinically the
Allergic Dermatitis
lesions are asymptomatic and manifest in different forms, have irregular verrrucous surface and keep on growing slowly. The number
of warts varies from single to several hundred. The individuals with depressed cell-mediated immunity due to treatment with
Patents
immunosuppressive drugs, Hodgkins'disease, malignant lymphomas and lymphocytic leukaemia are more likely to have a large
number of warts.
Mind

The different varieties of warts include the following : Common Warts or Verruca Vulgaris: These are characterized by firm, skin colour
Opportunities For
papules of various sizes with verucous surfaces and can occur on any parts of the body but are most commonly present on the
Homeopathic Graduates
dorsum of the hands and fingers. Plain Warts or Verruca Plana: It presents as skin colored, slightly raised flat -topped papules and
are usually present on dorsum of hand and face. Filiform Warts: These are finger like projections with irregular surface and are usually
Pamphlet On Psoriasis
seen on the neck, face and scalp. Plantar warts: These are found on any part of the sole. The lesions are occasionally painful. The
warts present as skin colored well defined areas in the sole with irregular surface. Genital warts: These warts are usually transmitted
Pamphlet On Vitiligo
through sexual contact. These are present as fungating masses of verucous tissue. They usually present on glans penis, corona,
mucosal surface of prepuce and occasionally on the urinary meatus in males and the vulva and vaginal openings in the females.
Cost Effectiveness And
Efficacy Of Homeopathy In Molluscum Contagiosum: Large virus belonging to the pox group of viruses causes it. It gets implanted on the skin by contact with an
Primary Health Care infected individual.

Auto - inoculation after infection is very common which causes the spread of the disease to the different parts of the body. The
Evidence Based
disease is common in children. When it is present on the genitals of an adult male or female transmission is usually through sexual
Homeopathy in Dermatology
exposure. It manifests in the form of asymptomatic, pearly white or pink papules with well-defined depressed centers known as
umbilication. After trauma or spontaneously after a few months, inflammatory changes result in suppuration and crusting leading to
Homeopathy In Multi Drug
destruction and disappearance of the lesions.
Resistance Pulmonary-
Tuberculosis The course of warts and Molluscum Contagiosum is unpredictable, peculiar and inconsistent therefore it is often difficult to evaluate
the results of any treatment. The various modalities are available for the treatment of warts in various systems of medicine include
PPP in the Provision of electrocoagulation, cryosurgery 1, curetage 2, trichloracetic acid, silver nitrate, poddophyllin urea 3, formalin soaks 4, vitamin A acid
Homoeopathic Services application 5, calcium hydroxide solution soaks 3, bleomycin local injection 6 and hypnosis 3,7. It is known that Homoeopathic drugs
are very effective for the treatment of Warts/Molluscum contagiosa. Many cases and reports are available confirming the efficacy but
Research and Development no report is based on double blind study 8,9,10. In the study undertaken during 1986-88 it was revealed that some of the
homoeopathic medicines were found effective 75-90% in the treatment of different types of warts. Keeping in view the possibility of
Campaign on Homeopathy spontaneous remissions in warts it is desirable that a double blind placebo control trailed is conducted with the drugs found very
For Healthy Mother And  useful in the treatment of warts/molluscum.
Happy Child
Aims & Objectives
Drug Formulary of
Homoeopathy  To evaluate the efficacy of selected homeopathic drugs found useful in the treatment of warts in open clinical trials using
control trials.
Proposed amendment in RR
 To evaluate the efficacy of Calcarea carb in the treatment of Mollusum contagiosum
GDMO(H)

Material & Methods

A problem oriented Performa having provision of recording all the symptoms pertaining to warts and the person as a whole was
designed and used in the trials. The duration, size, number, sensations in the warts in respect of each case was recorded on this
Performa. All the cases were diagnosed and assessed clinically.

Study Designs

Two types of placebo controlled double blind clinical trials were undertaken.

Cross over design : The subjects were given both drug and the placebo. This study was carried out during 1995-96.

Parallel design : One group received the drug and other group received placebo. This trial was carried out during 1996-97.

Both the trials were carried out at Nehru Homoeopathic Medical College & Hospital.

Inclusion Criteria

 Any age group

 Cases of Verruca Vulgaris, Verucca Plana, Verruca filiformis, Verucca plantaris and Verruca genitalis.

 Cases of Molluscum Contagiosum.

Exclusion Criteria

 Cases on immunosuppressive drugs

 Cases having active treatment for other diseases.

Project Report 1:

The study was started in the month May 95 and was concluded on 30th April 96 and 60 cases [35 Males, 25 Females] having different
types of warts were registered. Results of 43 Cases [25 Males, 18 Females] were analyzed and 17 cases were dropped out. All the
cases were given pre-coded (Thuja, Ruta, Calcarea carb, Dulcamara, Nitric acid, Causticum) drugs or pre-coded placebo at random for
a period of 15 days. The pre-coded drugs of 30 potency were given in TDS dose, 200 potency was used in BD doses and 1M potency
was used in OD doses. Prescribing indication used:

Calcerea carbonicum was given to all the cases of Mollusum contagiosum.

Ruta was used for smooth warts on face and palms and plantar warts having soreness.
Nitric acid was used for common warts having cauliflower like appearance, hard, large and bleeding easily.
Dulcamara was given for plain fleshy warts on face and hands.
Causticum was used for small as well big warts over hands and peri ungual region.
Thuja was used in all other cases of warts having different types and locations, irrespective of any constitutional indications.

After decoding the experiment the details of the responses received are as under:

Results after decoding the treatment

Cases Total 100% Active Resp. Placebo Resp. Drug- Resp. Only Resp.
Drug in % Group in % Plac. in % Plac. in %
Group Group

Verruca 21 18 10 55.56 8 44.44 7 38.89 1 5.56

Vulgaris

Verruca 07 04 03 75.00 1 25.00 1 25.00 0 0.00

Vulgaris

Verruca 05 03 02 66.67 1 33.33 0 0.00 1 33.33

Vulgaris

Molluscum 10 08 06 75.00 2 25.00 2 25.00 0 0.00

cont.

Total 43 33 21 63.64 12 36.36 10 30.30 2 6.06

Observations:

1. 63.6% cases improved with active drug and 36.36% cases improved with placebo in our study. The improvement indices of
active drug group are far better than the placebo group which clearly indicates that the homoeopathic drugs definitely
possess power to cure warts and Molluscum contagiosum.
2. In this research study design, each case was initially given a drug code in 30 potency which could be either active drug or
placebo. If the case did not improve with this code, the next code of 200 potency was given which could again be either
active drug or placebo. Therefore it was found after decoding, that some cases who were initially on active drug code in 30
potency received placebo in the next drug code of 200 or 1 M potency or vice a versa.
3. Among 36.36% improved cases under the placebo group, it was found that 30.30% received an active drug in the preceding
drug code and therefore this could be attributed to carry over effects of active drug. Only 6 % improved cases under placebo
group were found to be only on Placebo throughout the trial period. This observation is very significant.
Project 2

The study was started in the month May 96 and was concluded on 30th April 97 and 124 cases [81 Males, 43 Females] having
different types of warts and Molluscum contagiosum were registered. Results of 104 Cases [71 Males, 33 Females] were analyzed
and 20 cases were dropped out.
All the cases were given pre-coded drugs Thuja, Ruta, Calcarea carb and Causticum following double blind placebo controlled study,
parallel design for a period of 15 days. The pre-coded drugs of 30 potency were given in TDS doses, 200 potency was used in BD doses
and 1M potency was used in OD doses.
This study had much larger size than the previous one and care was taken to avoid carry over effects of homoeopathic medicines
adopting different research design. The data pertaining to reporting cases is as follows:

DRUG WISE RESPONSE AFTER DECODING

Drug Total Res % Drug Res ponse % Placebo Res ponse %

ponse

Thuja 42 24 57 27 22 81 15 05 33

Caust. 29 17 58 19 13 68 10 04 40

Ruta 19 09 69 10 07 70 03 02 66

Cal.carb 20 14 70 13 13 100 07 01 14

Type of Warts Response

Type Total Improved 100% Improved with drug % Improved with placebo %

Total cases 104 64 52 81 12 19

V.Vulgaris 39 17 12 70 05 30

V.Plana 20 16 12 75 04 25

V.Plantar 12 10 08 80 02 20

V.Filiform 12 06 06 - - -

V.Genitalis 01 01 01 - - -

Molluscum 20 14 13 93 01 07

Observations

1. The results of active drug group are far better than the placebo group. This again reconfirms the observation made in
previous project report that homoeopathic medicines are quite effective in the treatment of warts and Molluscum
contagiosum.
2. The improvement results of placebo group (19%) in this study under project 2 are significant as compared to those of 33.4%
in the project 1. This clarifies the doubtful observation of carry over effects of homoeopathic treatment and signifies that
probably homoeopathic medicines have no carry over effects in the treatment of warts and Molluscum contagiosum. Hence
the effectively of the indicated medicine can be perceived with in few days of its intake.
3. Among results of individual medicine, Thuja was found most useful drug for warts and Calcarea carbonicum in Molluscum
contagiosum. The sample sizes of active drug group and placebo group in respect of Ruta and Causticum are insufficient to
comment on the efficacy of these medicines in the treatment of warts.
Conclusion

The findings of earlier open studies and common belief that homoeopathy has a curative role in the treatment of warts and
molluscum contagiosum is re-established in these two studies.

References:

1. Limmer Bl, Louis BT. Cryosurgery of plantar wart. J Am Pod Asoc 1979; 69:713
2. Davidson MR. Skin crettage and the treatment of plantar verruca. J Am Pod Assoc 1976; 66: 331-6
3. Clinton WL. Verruca, a Dermatologic problem. JAMA 1950, 44 : 1361-5.
4. McKnight AG. Assessment of treatment of plantar warts. Ulster Med 1968; 40: 40-53.
5. Bersaqures JD. Vitamin A acid in the topical treatment of plantar wart. Dermatologica 1975; 150: 369-71.
6. Hudson AL. Treatment of plantar warts with Bleomycin. Arch Derm 1976; 112: 1179.
7. Moorris Brians AP. Hypnotherapy of warts using The Simonton visualization technique. Am J Clin Hypnosis 1985; 27: 237-
40.
8. Sehgal V.N. Thuja, an antibacterial agent in the management of wart. Indian J Derm and Ven 1967; 33:37-39.
9. Chand DH, Verucca. Br. Hom J 1986; 175: 18-26.
10. Boericke W. Pocket Manual of Homoeopathic Materia Medica with Repertory. Pp. 55-918. New Delhi: B. Jain 1987
11. Gupta Ramji, Bhardwaj O.P. & Manchnda R.K. Homoeopathy in the treatment of warts. Br. Hom. J 1991; 80: 108-11

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