Httpsbasem - Co.ukwp Contentuploads202104Physical Activity A Guide For Health Practitioners V10 PDF
Httpsbasem - Co.ukwp Contentuploads202104Physical Activity A Guide For Health Practitioners V10 PDF
Httpsbasem - Co.ukwp Contentuploads202104Physical Activity A Guide For Health Practitioners V10 PDF
movement
for movement
F
or the past six years, the physical activity educational programme Motivate2Move
has collaborated with the Movement for Movement undergraduate programme with
the common goal of training all student health professionals in the health and societal
benefits of physical activity and exercise.
The Motivate2Move team are again delighted to produce this 2020 edition of the student
guidebook for Movement for Movement. Updated extensively to include more medical
conditions, illustrative diagrams and practical advice, the guidebook has been described as
‘essential reading’ for all health care students.
As this guidebook has been developed throughout 2020, the world has been dealing with
the fallout from the Coronavirus infectious disease (COVID-19) pandemic that has affected
millions of people world-wide. COVID-19 has had far-reaching effects on our physical and
mental health, as well as devastating social and economic consequences. What has also
become clear, is that the most vulnerable in our society – older adults, the chronically ill
and the socially deprived - have suffered the most. Furthermore what has also been
highlighted is the importance of physical activity for both the prevention of chronic disease
linked with COVID-19 severity (i.e. obesity, diabetes) and the safeguarding of our mental
health and wellbeing.
In the light of this, Motivate2Move has produced a new section on the role of physical
activity and exercise in supporting the body’s immune system and how being more
physically active might potentially minimise the severity of symptoms of COVID-19 if
infected. With evidence now emerging that people have been less active during the
pandemic, educating health professional students about the benefits of physical
activity for health and wellbeing is more important than ever.
Dr Brian Johnson
November, 2020
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 2 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CONTENTS
Introduction ...............................................................................................................................7
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 3 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CONTENTS
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 4 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CONTENTS
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 5 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CONTENTS
Acknowledgements .............................................................................................................................61
References
movement
for movement
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 6 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
Introduction
The purpose of this guidebook is to give students of all health care professions, the background information
to educate and motivate patients about the health benefits of physical activity.
Regular physical activity provides a range of physical and mental health benefits. These include reducing the
risk of disease, managing existing conditions, and developing and maintaining physical and mental function.1
More details on the conditions that benefit form physical activity follow in other parts of this resource.
It also contributes to a range of wider social benefits for individuals and communities, which include: improved
learning and attainment, managing stress and wellbeing, improved sleep, the development of social skills, and
better social interaction.1
Designed as brief information ‘bites’, the guide covers all aspects of physical activity and health from general
information to practical disease specific recommendations. It comprises four main sections:
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 7 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 1:
Figure 1:
Benefits of exercise on
Increased cardiac output, the immune system
blood flow and stress
hormones
Exercise-induced
mobilisation of
Improvements in Immune
immune cells Immune Function
Cell Mobilisation • ↑ innate & adaptive immunity
Numbers • ↑ response to viral & bacterial
in Blood infections
• ↑ surveillance of cancer cells
Migration
• ↑ antibody production
• ↑ response to vaccination
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 8 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 1:
4. Environmental factors
From the studies conducted, exercise volume (intensity x • Air travel – exposure to hypoxia, radiation, pollution,
duration) of individual and consecutive sessions appears to be sleep disruption and dehydration
the key factor driving alterations in markers of immune function. • Extremes of temperature, humidity and altitude
It is believed that these alterations relate to the depletion of • Breathing cold, dry or polluted air
muscle glycogen and/ or depletion of energy reserves within • Allergies
immune cells, although these claims require further research to
be substantiated 3,32. The points of contention on this topic are
multiple, but primarily relate to disagreements over study design, Section 3: Staying active during the COVID-19 pandemic
validity of the biomarkers examined, appropriate diagnosis of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection and the immunological techniques used 3. It is important is the strain of coronavirus known to cause COVID-19, an infection
to emphasise that the data indicating that high volumes of training of the lower respiratory tract that has caused widespread
can causatively supress immunity need to be considered in the infection, morbidity and mortality worldwide. The government
context of a range of other factors that can adversely affect lockdown on March 23rd 2020 resulted in a new way of life for
immunity (see box 2) 33. The body cannot distinguish between the British population. Isolation has confined individuals and
these different types of stress, and many of these variables families to their homes for prolonged periods, with restricted
intertwine with exercise volume when ‘suppressing’ measures of time outdoors. Emerging data from across the world are already
immunity (e.g. stress induces cortisol release, which can suppress indicating that lockdown resulted in reduced physical activity 35
immune function). It is clear that heavy sessions of exercise, and increased sedentary time 35,36. Even as lockdown restrictions
particularly if repeated over consecutive days, can dramatically ease, it is possible that these habits are maintained, which in
alter markers of immune function 18–27; however, the evidence does conjunction with the stress of the situation could be detrimental
not support a direct relationship between exercise load and an to immune function and the risk of further developing chronic
increased risk of infection. Indeed, a recent consensus statement health conditions 37. Further, the likelihood of subsequent waves of
from the International Olympic Committee suggests that elite infection may result in reinstatement of lockdown, so these forced
athletes who effectively manage their behavioural (i.e. minimise lifestyle and habit changes may be ongoing.
pathogen exposure) and lifestyle habits (i.e. stress, sleep and Given that we are still in the infancy of what could be long-term
nutrition) are not more likely to have a higher risk of infection, changes to our way of life, there is time to alter daily activity and
despite their very high training volumes 34. exercise habits to minimise the severity of symptoms of COVID-19,
if infected. There are no empirical data to indicate that being more
A key take home message for the general population is that there physically active or engaging in regular moderate-to-vigorous
is no evidence to indicate that engaging in vigorous intensity intensity exercise can directly reduce susceptibility to COVID-19
exercise within or even slightly over the recommended guidelines and/ or the severity of its symptoms.
of 150 minutes per week is detrimental to immune function. On the However, by building on the literature described in section 1, we
contrary, regular engagement in moderate to vigorous physical can intuitively suggest potential benefits of regular moderate-to-
activity and structured exercise is critical to stimulating the vigorous exercise that can enhance immune function and could
immune system to perform its job effectively. reduce the severity of COVID-19 symptoms and shorten recovery
times (see box 3 on next page).
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 9 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 1:
Section 4: Practical considerations for lockdown and beyond • Myokines: cytokines and other small proteins released from
Being more physically active and/or engaging in regular amounts skeletal muscle in response to contraction
of moderate-to-vigorous intensity exercise improves multiple
aspects of immune function, which lowers one’s risks for infection • Antibodies: proteins produced by B-cells in order to kill a
and chronic diseases. Some specific considerations about daily previously encountered infection (found in blood, saliva, tears
activity and exercise are highlighted below: and the mucosal surfaces of certain tissues, e.g. gut
and respiratory tract)
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 10 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 2:
Physical inactivity has been identified as a leading risk factor for global mortality and a contributor to
the global rise in overweight and obesity. Yet, much of the world is becoming less active. As countries
develop economically, levels of inactivity increase. In some countries, these levels can be as high as 70%,
due to changing transport patterns, increased use of technology, cultural values and urbanization.
GAPPA also identified as a priority the updating of the WHO 2010 guidelines on physical activity in youths,
adults and older adults.
As a result, WHO has now developed guidelines for children and adolescents, adults, older adults and for
the first time make specific recommendations on physical activity in sub-populations such as pregnant
women and those living with chronic conditions or disability2. These guidelines will therefore replace the 2010
recommendations on physical activity for health. The separate WHO guidelines on physical activity, sedentary
behaviour and sleep for children under 5 years of age complement this update.
Many countries have developed their own guidelines, but the WHO guidelines present advice on these topics
if national guidance is not available, are available here.
For those people using this guidebook we present the 2019 UK Physical Activity Guidelines below.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 11 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 2:
This summary of the new guidelines is drawn from the 2019 UK Infants (less than 1 year):
Chief Medical Officers physical activity guidelines documents.1 • Infants should be physically active several times every day, in
a variety of ways, including interactive floor-based activity
Physical activity guidelines for Under-5s e.g. crawling.
The evidence-base on physical activity in the Under-5s has
expanded substantially since the development of the previous • For infants not yet mobile, this includes at least 30 minutes of
set of guidelines2 There is now a large body of evidence that the tummy time spread throughout the day while awake (and other
amount of physical activity in the Under-5 period influences a wide movements such as reaching and grasping, pushing and pulling
range of both short-term and long-term health and developmental themselves independently, or rolling over); more is better.
outcomes.3,4 For example, low levels of physical activity have been
recognised as a contributor to increasing rates of child obesity NB: Tummy time may be unfamiliar to babies at first, but can
in this age group.5, 6 It has become very clear that higher levels be increased gradually, starting from a minute or two at a time as
of physical activity are better for health, and lower levels worse, the baby becomes used to it. Babies should not sleep on
and that there are benefits to increasing levels of physical activity their tummies
across the distribution of starting physical activity level.3, 4
Toddlers (1-2 years):
Despite concern over levels of physical activity in the Under-5s, in • Toddlers should spend at least 180 minutes (3 hours) per day in
both boys and girls, the average level of physical activity reaches a variety of physical activities at any intensity, including active
a lifetime peak around the age of school-entry (5 years old) and and outdoor play, spread throughout the day; more is better.
declines thereafter (17-19 years old). Maximising the higher levels of
physical activity in the early years should therefore help maintain Pre-schoolers (3-4 years):
higher levels later in childhood and adolescence.3,4,7,8 • Pre-schoolers should spend at least 180 minutes (3 hours) in a
variety of physical activities spread throughout the day, including
active and outdoor play. More is better; the 180 minutes should
include at least 60 minutes of moderate-vigorous intensity
physical activity (MVPA).
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 12 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 2:
Children and young people (5-18 years of age): Adults (aged 19-65):
• Should engage in moderate-to-vigorous intensity physical • For good physical and mental health, adults should aim to be
activity for an average of 60 minutes per day across the week. physically active every day. Any activity is better than none, and
(This activity can include all forms of activity such as physical more is better still.
education, active travel, after-school activities, play and sports).
• Adults should do activities to develop or maintain strength in
• Should engage in a variety of types and intensities of physical the major muscle groups. These activities could include heavy
activity across the week to develop movement skills, muscular gardening, carrying heavy shopping, or resistance exercise.
fitness, and bone strength. Muscle strengthening activities should be done twice a week, but
any strengthening activity is better than none.
• Should aim to minimise the amount of time spent being
sedentary and when physically possible should break up long • Each week, adults should accumulate at least 150 minutes
periods of not moving with at least light physical activity (2 1/2 hours) of moderate intensity activity (such as brisk walking
or cycling); or 75 minutes of vigorous intensity activity (such
Download Children and young people infographic here: as running); or even shorter durations of very vigorous intensity
activity (such as sprinting or stair climbing); or a combination of
moderate, vigorous and very vigorous intensity activity.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 13 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 2:
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 14 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 2:
Le
ab
isu
aim for
nd
at least
re
ta
150
Ou
minutes
of moderate intensity activity
every week
Build
Start back up
pelvic floor to muscle
exercises as strengthening
soon as you can activities twice
and continue daily
Home a week
Physical activity can be safely be recommended to women benefits for disabled adults of engaging in physical activity were
after pregnancy and have no negative impact on breast comparable with those for the rest of the adult population.
feeding postpartum. It concluded that any myths about physical activity being
After the six to eight week postnatal check and depending on inherently harmful for disabled people should be dispelled.
how the woman feels, more intense activities can gradually
resume, i.e. building up intensity from moderate to vigorous Download the physical activity for disabled adults here:
over a period of at least 3 months.
Download the Physical activity for women after child birth Key principles of physical activity
infographic here:
Physical activity for good health and wellbeing
Regular physical activity provides a range of physical and
Physical activity for disabled adults mental health benefits. These include reducing the risk of
Disability refers to people who have long-term physical (e.g. disease, managing existing conditions, and developing and
spinal cord injury), sensory (e.g. visual impairment), cognitive (e.g. maintaining physical and mental function. More details on the
learning difficulties), and/or mental impairments (e.g. depression) conditions that benefit form physical activity follow in other
which in interaction with various barriers may hinder their full parts of these resources.
and effective participation in society on an equal basis with
others. Rather than focusing on just one impairment the UK CMO Some is good, more is better
guidelines considered a range of impairments. Our understanding of the relationship between physical activity
and health has grown. In general, the more time spent being
See United Nations Convention on the Rights of Persons physically active, the greater the health benefits. However, we
with Disabilities. now know that even relatively small increases in physical activity
can contribute to improved health and quality of life. The gains
UK CMO’s have reviewed the evidence base on physical activity are especially significant for those currently engaging in the
and the general benefits for disabled adults16. It found that with lowest levels of activity (fewer than 30 minutes per week), as
respect to safety, no evidence exists that suggests appropriate the improvement in health for each additional minute of physical
physical activity is a risk for disabled adults and that the health activity will be proportionately be greater (Fig 1 on next page).
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 15 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 2:
+
Health benefits
Strengthening activities are important throughout life for Wider benefits of being active
different reasons: to develop strength and build healthy bones Physical activity not only promotes good health and functioning
during childhood and young adulthood; to maintain strength and helps prevent and manage disease. It also contributes to a
in adulthood; and to delay the natural decline in muscle mass range of wider social benefits for individuals and communities.
and bone density which occurs from around 50 years of age,
maintaining function in later life. The relevance and importance of the wider benefits of physical
activity for individuals vary according to life stage and various
other factors but include: improved learning and attainment,
managing stress and improved wellbeing, improved sleep, the
development of social skills, and better social interaction.
Balance training involves a combination of movements that • The UK General Practice Physical Activity Questionnaire
challenge balance and reduce the likelihood of falling 21. (GPPAQ)22 can be used to categorize patients into
Different activities have differential effects on muscle recommended levels of activity.
and bone strength and balance.
Download the GPPAQ questionnaire and read codes here:
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 16 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 2:
• ‘The Scot-PASQ’.23 A brief assessment using just three questions. Take home messages:
Used as a motivational screening tool to help raise the issue of • Physical activity is an important part of the lifestyle for any
physical activity and deliver advice patient because of the overwhelming evidence of the health
benefits at all ages.
o In the past week, on how many days have you been physically
active for a total of 30 minutes or more? • Being active every day provides a foundation for a healthier and
happier life.
o If four days or less, have you been physically active for at
least two and a half hours (150 minutes) over the course of • Even relatively small increases in physical activity can contribute
the past week? to improved health and quality of life.
o Are you interested in being more physically active? • Regular strength and balance activities are important throughout
life: being strong makes all movement easier and increases our
Read the brief guidance on how to use the Scot-PASQ tool by ability to perform normal daily tasks.
downloading it here:
• Any activity is better than none.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 17 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 3:
Cancer
Although Cancer develops at a cellular level it is known to be Physical activity has been shown to improve quality of life during
influenced amongst others, by genetic, environmental and lifestyle the rehabilitation phase and should therefore be encouraged.13 - 17
factors via a number of interacting biological mechanisms.
Physical activity and palliative care: Despite a small evidence
Inactivity or largely sedentary behaviour is now widely base, intervention studies are promising and support the use of
recognised as a key component in the risk factors of physical activity in those in the advanced stages of cancer.18-21
several cancers. Benefits demonstrated include:
• Slowed decline in quality of life
There is clear data for the positive effects of physical activity • Preserved functional outcomes (e.g. walking ability,
both on the prevention of some cancers and on clinical muscular strength)
outcomes after diagnosis. • Less severe symptoms (dyspnoea, appetite loss)
Physical activity and primary prevention Physical activity and survival rates: An increasing number of
The leading authority on the links between physical activity as an studies have studied the relationship between physical activity
independent risk factor for the primary prevention of cancer is the and cancer survival. There have been reviews and studies across
World Research Fund’s Continuous Update Project.1 The evidence breast, colorectal, prostate, ovarian, lung and glioma brain cancer.
here is for physical activity as the only independent risk factor, 22-29
Although, this is still emerging evidence, these studies have
some cancers also have weight as a risk factor. shown an inverse relationship between physical activity and
mortality in people undertaking post diagnosis physical activity.
Strong convincing evidence Limited – no conclusion
Colon Bladder Rectal Risk reduction rates varies on these studies, from 15-67% for cancer
Strong probable evidence Kidney Skin specific mortality and 18 -67% for all-cause mortality.25 However,
the dose of physical activity to reduce cancer mortality varied
Breast (post-menopausal) Mouth/throat Stomach
between studies from 9 MET-hr (metabolic equivalent time) to 27
Breast (pre-menopausal) for vigorous exercise Ovary MET-hr, equivalent to approximately 180 to 500 minutes per week
Endometrial Pancreas respectfully, of moderate intensity physical activity. It is suggested
Limited - suggestive Prostrate that the association between physical activity and cancer-specific
mortality is not uniform and may vary according to the volume of
Liver Oesophagus Unlikely effect on risk
physical activity and between different cancer types.25
Lung Breast (pre-menopausal) None identified to date
NICE guidelines CG101 (2018)30 and CG81 (2017) 31 back up the
Physical activity pre-treatment: Pre-surgical exercise, through advice to those with early and advanced breast cancer, that
aerobic, resistance or pelvic floor training, may benefit cancer we should provide the information and access to an exercise
sufferers through effects on function and cardiovascular and programme to help with cancer related fatigue, lymphoedema
pulmonary fitness with emerging evidence of improvements and quality of life.
shown in:2- 5
• Rates of incontinence in prostate cancer Safety considerations during and after treatment 32
• Functional walking capacity
• Cardiorespiratory fitness
• Reduced hospital stays To avoid symptom exacerbation To prevent falls
Modify exercise Practice balance exercises
Physical activity during treatment: Although feeling unwell before Start moderately and progress slowly Practice strength exercises
or during treatment for cancer, physical activity helps maintain
During immunosuppression For people with lymphoedema
functional abilities and wellbeing and:6 - 9
• Significantly improves fitness and muscle strength Avoid high load/intensity Progress slowly
• Shows small improvements in anxiety levels and self esteem Monitor bloods for neutropenia Wear compression garments
• Shows evidence of an improvement of fatigue levels, greatest
in those with worst fatigue
• Increases lean muscle mass
Contraindications 33
• Improves arm function with no worsening of lymphoedema
In disease or treatment avoid activities that:
in breast cancer 10, 11 • Require high intensity in people with low Hb < 8.0g/dl
• Entail an increased risk for bacterial infection in people with
Physical activity after treatment: There is often a loss of physical a low wbc < 0.5 x 109/l
function as a result of their cancer treatments, but evidence
shows that physical activity after treatment can improve several
aspects: 6-9,12
• Increase in cardiovascular fitness and muscular strength
• Reduced fatigue, greatest in those with worse fatigue
• Improvements in quality of life, anxiety and depression
• Some reductions in body fat and increase in muscle mass
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 18 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 4:
Cardiovascular Health
Ischaemic heart disease cardiac rehabilitation services for varied reasons.9 These should be
explored with the individual by primary and secondary care to see
Primary prevention: There is a clear inverse relationship between if any barriers to the individual can be overcome.
physical activity and cardiovascular disease (CVD) which is dose
responsive, with the largest benefits occurring when moving from NICE guideline CG172 on Myocardial infarction: cardiac
no activity to low levels of activity. Additional benefits do occur rehabilitation and prevention of cardiovascular disease10
with higher levels of activity.1 The reduction in cardiovascular recommend:
mortality is of the order of 20-35%, depending on the level of
physical fitness.2 • Offer cardiac rehabilitation programmes designed to motivate
people to attend and complete the programme. Explain the
Mechanisms which contribute to this effect from exercise benefits of attending
interventions are multiple: 3 - 4
• Direct cardiovascular effects on the heart • People should be advised to undertake regular physical activity
o Lower heart rate at rest and during exercise sufficient to increase exercise capacity
o Lower blood pressure at rest and during exercise
o Lower relative oxygen demand • They should be advised to be physically active for 20-30 min a
o Increased plasma volume day to the point of breathlessness
o Increased stroke volume
o Increased myocardial oxygen supply • People not achieving this should be advised to increase their
o Increased myocardial contraction electrical stability activity in a gradual step-by-step way, aiming to increase their
o Improved vascular endothelial function exercise capacity
o Decreased blood coagulability
o Increased coronary blood flow, coronary collateral vessels • They should start at a level that is comfortable, and increase the
and myocardial capillary density duration and intensity as they gain fitness
• Metabolic effects • The benefit of exercise may be enhanced by tailored advice from
o Increased high density lipids a suitable qualified professional
o Decreasing harmful low density cholesterol
o Improved insulin sensitivity
Contraindications to referral for exercise 11
• Unstable angina,
NICE guideline CG 1815 on Cardiovascular disease: risk assessment • Systolic blood pressure 180 and/or diastolic 100 mmHg,
and reduction, including lipid modification recommend: Lifestyle • BP drop > 20 mmHg demonstrated during ETT,
modifications for the primary and secondary prevention of CVD. • Resting tachycardia > 100 bpm,
• Advise people at high risk of or with CVD to do the • Uncontrolled atrial or ventricular arrythmias
following every week: • Unstable or acute heart failure
o At least 150 minutes of moderate intensity aerobic activity or
o 75 minutes of vigorous intensity aerobic activity or a mixture
of moderate and vigorous aerobic activity in line with national Erectile dysfunction
guidance for the general population Erectile dysfunction (ED) is the persistent inability to obtain or
o Advise people to do muscle-strengthening activities on 2 or maintain an erection satisfactory for sexual activity. Provided
more days a week that work all major muscle groups (legs, alternative hormonal, neurological and psychological causes are
hips, back, abdomen, chest, shoulders and arms) in line with excluded, then ED is thought to have a vasculogenic aetiology and
national guidance for the general population shares common risk factors with cardiovascular disease (CVD):
age, hypercholesterolaemia, hypertension, metabolic syndrome,
• Encourage people who are unable to perform moderate-intensity insulin resistance and diabetes, smoking, obesity, sedentary
physical activity because of comorbidity, medical conditions or behaviour and depression.1
personal circumstances to exercise at their maximum safe capacity
Many studies has established that ED is associated with
• Advice about physical activity should take into account the asymptomatic coronary artery disease (CAD) and that the ED
person’s needs, preferences and circumstances. Agree goals and precedes the CAD, stroke and peripheral arterial disease by a
provide the person with written information about the benefits of period of 2-5 years (average age 3 years). 2, 3 A meta-analysis also
activity and local opportunities to be active concluded that men with ED compared with subjects without have
a 44% higher risk for total cardiovascular events.2
Secondary prevention: in established heart disease, regular
adapted exercise is required to reduce mortality, and habitual This has important clinical implications for men presenting with
physical activity has been shown to reduce all-cause mortality ED. Careful history taking, including CVD symptoms, CVD risk
by 25-30%.6 The evidence of cardiac rehabilitation if it is used, is factors and presence of co-morbidities, is essential. Lifestyle
associated with a reduction in morbidity, cardiac mortality (26%), changes are then effective in improving sexual function in men;
hospital readmissions (18%) and improved health-related quality these include physical exercise, improved nutrition, reduced
of life.7, 8 The uptake of cardiac rehabilitation in England is 50%. alcohol intake, weight control and smoking cessation. 2, 3
This reflects that half of eligible people are still not taking up
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 19 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 4:
Cardiovascular Health
Heart failure The European Heart Rhythm Association ( EHRA) and European
Trials support the evidence of the beneficial effect of physical Association of Cardiovascular Prevention and Rehabilitation
activity training in people with stable heart failure in NYHA class I, (EACPR), endorse the current evidence, which would suggest
II and III. 1-3 that moderate physical activity is associated with improved
cardiovascular health, decreased mortality and a decreased
Although there is no evidence of increased or decreased all-cause risk of AF.1
mortality in the short term (up to 12 months), the benefits of
exercise have been shown by meta-analysis to: 2,4,5 Obstructive sleep apnoea syndrome (OSAS)
• Physiologically increase VO2 max
• Functionally increase walking speed and tolerance
• Significantly reduce hospital admissi ons
• Improve quality of life.
Contraindications
Heart failure which is acute, unstable 7 or severe NHHA class 1V1
Figure 1. Partial and complete airway obstruction resulting in hypopnea and apnea,
respectively. Reprinted from Hahn PY, Somers VK. Sleep apnea and hypertension.
In: Lip GYH, Hall JE, eds. Comprehensive Hypertension. St. Louis, Mo: Mosby;
2007:201–207. Copyright Elsevier 2007. Used with permission
Atrial fibrillation (AF)
Atrial fibrillation (AF) is the most common cardiac arrhythmia, Repetitive bursts of sympathetic activity, surges of BP and
associated with significantly increased morbidity and mortality of oxidative stress, brought on by pain and episodic hypoxaemia
stroke, dementia, heart failure and myocardial infarction. 1 associated with increased levels of mediators of inflammation, are
thought to promote endothelial dysfunction and atherosclerosis.
Physical activity is known to lower cardiovascular morbidity 6
For these reasons, increased physical activity is recommended
and mortality and physical inactivity is a major risk factor of as part of the behaviour treatments for OSAS, that also include
cardiovascular disease.2 Habitual moderate physical activity avoiding alcohol, caffeine or other stimulants of wakefulness
may have several benefits that can reduce the incidence of AF: before sleep, discontinuation of sedating medications and obesity
lowering heart rate and blood pressure, improved glucose and control. 1 Continuous positive airway pressure remains the gold-
lipid control, weight loss, improved endothelial function, and lower standard therapy and reduces CV mortality and events. 7
systemic inflammation are just some of the benefits. 3 Conversely,
vigorous activity can cause acute catecholamine fluxes, autonomic There is strong evidence that habitual moderate-to-vigorous
tone changes, and atrial stretch, all which may contribute to an physical activity reduces the risk of excessive weight gain, an
increased AF risk. 1, 5 important risk factor for obstructive sleep apnoea, indicates that
physical activity could have a favourable impact on the incidence,
Whether physical activity increases or decreases the risk of AF has as well as the treatment of, obstructive sleep apnoea. 5
been unclear/controversial, with the reported relationship between
physical activity and AF varying between studies. 4 Hypertension
The evidence supports an inverse relationship between physical
A large meta-analysis of 22 studies (656,750 individuals) has activity and the incidence of hypertension, with inactive individuals
reported that moderate physical activity does protect against AF who are less active and fit having a 30-50% greater risk of
in both men and women. 6 However, vigorous exercise appears high blood pressure. 1,2 However, the optimum prescription for
to increase the risk of AF in men, but whilst remaining protective the prevention of hypertension remains elusive. 3 Apart from
against AF in women. prevention, it is also effective in treatment with clinically relevant
reductions in blood pressure.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 20 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 4:
Cardiovascular Health
• The acute effect of physical activity causes a decrease in blood In addition, a recent meta-analysis of randomised trials found, that
pressure lasting 4-10 hours, but may last up to 22 hours; thus, structured exercise achieved a modest but consistent reduction
daily activity may achieve clinically significant improvement 4 in high systolic blood pressure (>140/90) that was similar to those
seen with commonly used hypertensives. On average it was found
• For a long-term effect, regular maintenance physical that exercise reduced systolic blood pressure by a mean of 8.96
activity is required mmHg in hypertensive patients compared to matched controls. 13
(See Table 1)
• The effect seems to be greatest in those with
established hypertension Lipids
Isolated hypercholesterolaemia and mixed dyslipidaemia with high
• Review data support the observation that physical activity LDL cholesterol, high triglycerides and low HDL cholesterol are
training, with all forms of exercise, in hypertensive people can associated with an elevated risk of atherosclerosis.
show a reduction of 3-10 mmHg in systolic and 2-6 mmHg in
diastolic blood pressure respectively 5 Aerobic fitness training has been shown to be beneficial in
The BASES Expert Statement on Exercise
• The main recommendation is for aerobic fitness training but
reducing triglycerides 1,2 and elevating the protective HDL
cholesterol,3 with some effect in also lowering LDL cholesterol.1
Training for People with Intermittent
dynamic resistance and isometric resistance at moderate
intensity training is also beneficial 5,6 Best results are achieved with regular daily moderate intensity
Claudication due to Peripheral Arterial Disease aerobic exercise or vigorous exercise at slightly higher volumes of
• Reductions of this magnitude have important clinical implications the present UK guidelines, expending 1200-2000 kcal per week
o They are of a similar magnitude
Produced on to conventional
behalf of the medication
British Associationwhich of Sportequates to 360 minutes
and Exercise Sciencesmoderate
by Dr Garry activity
Tew,per week. This
o A 10mmHg reduction in systolic or 5mmHg in diastolic blood workload
Dr Amy Harwood, Prof Lee Ingle, Prof Ian Chetter andisProf
associated
Patrick with a 5-8% increase in HDL cholesterol
Doherty.
pressure would be associated with about a 40% lower risk of and a decrease in triglycerides of approximately 10%. 4 It should
stroke death and about 30% lower risk of death from IHD or
Introduction still supplement other interventions.
other vascular causesLower-limb
7
peripheral arterial disease is a type of cardiovascular distance at follow-up of 82 m (95% CI 72-92 m; follow-up ranging
o Even a 2mmHg reductiondiseasein insystolic
which theblood
bloodpressure is
vessels (arteries) Peripheral Arterial
that carry blood 6 weeks toDisease
2 years). The corresponding difference for maximum
associated with reductions of 10%
to the legs andare
and feet 7%hardened
in the risks of
and narrowed Peripheral
or blocked by arterial
walkingdisease (PAD)
distance was 120 maffects
(95% CIaround
51-190 m;13% of adults
10 trials, over
n=500).
the build-up
stroke and ishaemic heart disease of fatty plaques (called
respectively 7 atheroma). It affects50around Improvements
years old and is commonly of this magnitude
caused are by likely to help with independence.
atherosclerosis. Major
13% of adults over 50 years old, and major risk factors for its The same review also reported that there was moderate-quality1
risk factors include smoking, diabetes mellitus and dyslipidaemia.
development include smoking, diabetes mellitus and dyslipidaemia evidence for improvements in physical and mental aspects of
NICE guideline CG136 on 8
the clinical management of The
(Morley et al., 2018). The presence of peripheral arterial disease presence of PAD itself
quality of life, is also a
as assessed riskthe
using factor
SF-36 for cardiovascular
(Lane et al., 2017). A
primary hypertension in adults recommends
itself is also that
a risk factor for appropriate
other disease,
cardiovascular problems, such with meta-analysis
about 65% of ofdata
people with PAD
at 6 months also having
of follow-up showedclinically
the physical
guidance and written or audio-visual
as angina, heartmaterials to promote
attack and stroke. relevant cerebral
This is because the underlying or coronary
component summaryartery be 2 points(See
score todisease. 2
higherFigure 1)
in exercise
lifestyle changes are offered.
disease process, atherosclerosis, is a systemic
process, meaning that blood vessels elsewhere in the
body may also be affected.
Contraindications The most common symptom of peripheral arterial
Blood pressures of a systolicdisease>180 or diastolic
is intermittent >100 or
claudication higher
(IC), which is
should receive medication before
muscle pain orregular physical
discomfort activity
in the legs and/or9 buttocks
brought on by walking and relieved within minutes
on rest (see Figure 1). IC occurs due to an inability to
Pharmacology v physical sufficiently
activity increase blood flow (and oxygen delivery)
There is plenty of strong randomizedmetabolic
to match the demands
controlled trialofdata
the lower-limb
muscles during exercise and can cause marked
showing reductions in stroke risk in those taking antihypertensive
reductions in functional capacity and quality of life
medications.10 There is less evidence
(Morley et al., that
2018).they significantly
The walking distancereduce
or speed Figure1. 1.
Figure Intermittentclaudication
Intermittent claudication (IC)
(IC)due
duetotoperipheral
peripheral arterial disease.
arterial disease
the risk of all-cause mortality andsymptoms
at which myocardial occurinfarction, with the
depends on multiple Reproduced from Peripheral artery disease (Morley et al., 2018) with permission from BMJ Publishing Group Ltd.
factors Reproduced fromartery
Peripheral artery diseaseat(Morley et al., 2018)
Note: Iliac or femoral disease can cause symptoms multiple distal muscle sites.with permission
exception of thiazide diureticsincludingandtheangiotensin-converting
severity and site of the arterial enzyme
disease, from BMJ Publishing Group Ltd. https://doi.org/10.1136/bmj.j5842
inhibitors. 11 However, there walking pace, terrain,
is strong incline and
prospective footwear.
cohort evidence Note: Iliac or femoral artery disease can cause symptoms at multiple distal
that regular physical activity Treatments
can reduce for IC,
theaimed
risksat of
relieving symptoms and reducing muscle sites
all-cause versus control (95% CI 1-3; 5 trials, n=429). The corresponding
the risk of further12cardiovascular disease, include lifestyle changes difference for the mental component summary score was 4 points
mortality and cardiovascular mortality.
(e.g. stopping smoking, exercising more), vasoactive drugs (e.g. (95% CI 3-5; 4 trials, n=343). Again, such differences have the
naftidrofuryl oxalate) and revascularisation (i.e. angioplasty or potential to be clinically meaningful.
Intervention bypass surgery). In 2012, the United All-causeKingdom’s National Institute
mortality Cardio-vascular mortality Myocardial infarction
of Health and Care Excellence (NICE) published a clinical guideline Modes of exercise
ACE-I * 10%
on the management of peripheral arterial disease, which stated that 19% In most studies, exercise programmes NR have involved treadmill or
Thiazide a supervised exercise programme *9% NR
should be offered as a first-line track walking of sufficient intensity22% to bring on claudication pain.
therapy for IC (NICE, 2012). This statement provides an overview There is a strong evidence base for this type of training and clinical
β-blocker * 6% (NS) NR 8% (NS)
of the evidence on exercise training and recommendations for guidelines around the world cite it as the preferred modality
Ca2+ channel blockers people * -6% (NS)
delivering exercise programmes to this population. NR (e.g. NICE, 2012). Alternate exercise 29%modalities
(NS) have not been
Regular physical activity (self-reported) # 29% 30% extensively studied. However, a randomised NR trial of 104 participants
Evidence on exercise training provided evidence that both cycling and arm-cranking are viable
Regular physical activity Core(fitness
outcome tests) #
measures 41% 57% alternatives for improving walkingNR distances (Zwierska et al., 2005).
Walking ability and its impact on quality of life
NS: Not significant; NR: Not reported. *: Randomised control trials. #: Prospective are the most These modalities
cohort may be useful for patients who are unwilling or
studies
important outcome measures of intervention to clinicians and unable to walk because of the pain encountered. Resistance training
patients.
Table 1: Mortality and morbidity Measureswith
risk reductions of walking
long-termability include pain-freemedication
anti-hypertensive and maximum may have
and physical a complementary
activity 11 role (e.g. for improving muscular
walking distances (or times) obtained during standardised treadmill strength); however, it should not be used as a substitute for aerobic
testing, and the distance covered in the 6-minute corridor walk exercise because its impact on walking distances appears modest
PHYSICAL ACTIVITY: A GUIDEtest. FOR The ‘Gardner’
HEALTH treadmill test is(V10)
PRACTITIONERS commonly used, which 21 THE BENEFITS (e.g. OF
McDermott
PHYSICAL al., 2009). ON OUR HEALTH AND WELLBEING
et ACTIVITY
involves a constant speed of 3.2 km/h and an increase in gradient
of 2% every 2 minutes. Several generic and condition-specific Supervision
questionnaires have been used to assess quality of life, including the The systematic review of Gommans et al. (2014) reports the
CHAPTER 4:
Cardiovascular Health
The primary treatment option, before resorting to surgery is Treatment: there is a huge variation in the degree of disability after
exercise training as generally the disease responds poorly to a stroke. Once stabilised, an individualised aerobic fitness training
pharmacotherapy. 2 Meta-analysis reviews conclude there is high programme can increase the endurance for day to day activities,
quality evidence for supervised exercise programmes. These can mediated by improved mobility and balance and improves walking
enable walking an increased distance to the onset of pain by 89 function. 3, 6 This can improve self-confidence of people to take part
m and the maximum walking distance by 120 m. 3 Exercise should in physical activity themselves. 7 Similarly, muscle strengthening
continue lifelong, with an expected improvement in walking of the lower limbs has been shown to increase function thereby
distance and reduced pain. Additional benefits may include a improving quality of life. 4
higher quality of life and improved cardiovascular health. 4
NICE guideline CG 162 on stroke rehabilitation recommend: 8
Although Vasoactive drugs, such as Naftidrofuryl oxalate,
can improve walking distance,1 NICE only recommend it Strength training:
when a supervised exercise programme does fails to achieve • Consider strength training for people with muscle weakness
any satisfactory improvement AND the person declines no after stroke
surgical options.5
• Include progressive strength building through increasing
NICE guideline CG 147 on lower limb peripheral artery disease repetitions of body weight activities (for example, sit-to-stand
recommend: 5 repetitions), weights (for example, progressive resistance exercise),
• Offering a supervised exercise programme to all people with or resistance exercise on machines such as stationary cycles
intermittent claudication.
• Consider providing a supervised exercise programme Fitness training:
which involves: • Encourage people to participate in physical activity after stroke
o 2 hours of supervised exercise a week for a
three-month period • Cardiorespiratory and resistance training for people with stroke
o Encouraging people to exercise to the point of maximal pain should be started by a physiotherapist
• Offer all people with peripheral arterial disease, information, • Aim that the person continues the programme independently
advice, support and treatment regarding the secondary based on the physiotherapist’s instructions
prevention of cardiovascular disease in line with NICE guidance
• Physiotherapists should supply any necessary information about
interventions and adaptations so that where the person is using
Stroke an exercise provider, the provider can ensure their programme is
safe and tailored to their needs and goals
Primary prevention: the benefits of physical activity on the
prevention of stroke are well documented. 1-4 Risk factors for Walking therapies:
stroke include hypertension, type 2 diabetes and hyperlipidaemia • Offer walking training to people after stroke who are able to
all of which are beneficially affected by physical activity. It is not walk, with or without assistance, to help them build endurance
surprising then that there is a clear inverse relationship between and move more quickly
activity and risk of stroke. It is also clearly dose dependent and
depending on the amount of activity, the effect is a 20 - 35% • Consider treadmill training as one option of walking training for
lowering of risk. 1,3 people after stroke including those who require body support.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 22 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 5:
CKD - This term describes a group of progressive and irreversible Whilst studies are increasing, the evidence base in transplant
kidney disorders which are estimated to affect around 8% of the recipients remains small.
population in the UK. 1
Overall, both aerobic and resistance exercise are recommended
A progressive decline of renal function is associated with 2: due to their separate beneficial effects on cardiovascular health
• Increasing morbidity and mortality and skeletal muscle in these people, 23-26 who typically lead
• Muscle wasting and reduced physical function sedentary lifestyles27.
• Hypertension
• Anaemia The use of exercise in the treatment and rehabilitation of such
• Systemic inflammation people is relatively understudied, but there is now sufficient
• Metabolic co-morbidities, including type II diabetes and obesity evidence of the benefits for exercise to be mentioned in the
current NICE guidelines for the management of CKD:
A minority of people will eventually progress to end stage renal
failure (ESRF) requiring dialysis or transplantation, but by far the NICE guidelines CG182 28 on CKD in adults recommend:
most common cause of death is cardiovascular disease (CVD).2 • Encourage people with CKD to take exercise, achieve a healthy
weight and stop smoking. (2008)
People with CKD 3, 4 display poor physical fitness and reduced
exercise capacity, which is directly associated with all-cause The newly updated clinical practice guidelines29 from the UK Renal
mortality 5, 6. Physical activity levels vary amongst CKD Association for haemodialysis (2019) now recommend intradialytic
populations, with ~40% of non-ESRF individuals being physically exercise, i.e., exercising during haemodialysis treatment:
active, however levels decrease with disease progression and
are lowest amongst those receiving dialysis 7. However, higher • Intradialytic exercise should be available in all units, as a
levels of leisure time physical activity and walking are associated treatment for enhancing physical functioning, in patients without
with slower decline in kidney function, reduced risk of renal contraindication.
replacement therapy and mortality 8, 9.
• Intradialytic exercise may be considered as a method for
Benefits of exercise in CKD: enhancing quality of life.
Data coming from a number of systematic reviews and/or meta-
analyses10 - 15 and randomised controlled trials and experimental The American National Kidney Foundation guidelines include
studies16 - 24 into the effects of exercise across the spectrum of CKD a similar statement encouraging exercise, weight loss and
report the following benefits: smoking cessation in CKD; however, these current guidelines lack
specific advice for exercise and physical activity prescription.
• Significant positive effects on exercise capacity following all Greater information is provided in the 2012 American Kidney
types of exercise including, aerobic and resistance exercise Disease Improving Global Outcomes (KDIGO)30 guideline for
performed individually or in combination the management of blood pressure, who advocate performing
exercise “compatible with cardiovascular health and tolerance,
• Increased walking capacity aiming for at least 30 minutes 5 times per week”. Whilst current
clinical guidelines for exercise in the management of CKD people
• Significant positive effects of cardio-protective benefits and in the UK are lacking, more in-depth guidelines are included
reduction of cardiovascular risk factors including improved blood in the Swedish handbook ‘Physical activity in the Prevention
pressure control and reductions in arterial stiffness in non-ESRF and Treatment of Disease’ (FYSS in Swedish). 31 The UK Renal
CKD following aerobic exercise Association has commissioned the first UK exercise and lifestyle
guidelines for CKD (due in 2020).
• Reversal of CKD related muscle wasting with improvements in
muscle size and strength with progressive resistance exercise Precautions:
The usual absolute contraindications to exercise apply in CKD.
• Improved health related quality of life (e.g. depression, pain) See ‘Starting to exercise’.
following aerobic and resistance exercise performed individually
or in common The following can be considered CKD specific precautions and
contraindications 7, 11, 26, 32, 33:
• Reductions in systemic inflammation and circulating markers
of oxidative stress (malondialdehyde and 4-hydroxyalkenals) • With the high prevalence of CVD the people should have no
following aerobic exercise or stable angina, well controlled blood pressure and minimal
fluid retention.
• Improved allograft function (improved transplant function) in
people receiving a transplant • People with CKD are prone to fragility fractures and tendinoses
injuries with spontaneous tendon ruptures being reported in
The evidence base surrounding the benefits of exercise and CKD. Moreover, musculoskeletal and joint issues are likely to be a
physical activity in ESRF (in those requiring haemodialysis and common consequence of the initiation of exercise training due to
peritoneal dialysis therapy) is limited and many studies are at high the high prevalence of co-morbidities in most CKD sufferers.
risk of bias.23,24
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 23 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 5:
Therefore flexibility and stretching exercises along with a long People should be advised to incorporate increased physical
warm up and cool down period should be incorporated into a activity into their lifestyle wherever possible, gradually increasing
graded exposure to exercise. the intensity and duration. 35 To gain greater improvements in
aerobic capacity and muscle size and strength, people should
• People with polycystic disease kidneys and those with a kidney be encouraged to progress to moderate intensity, but the
transplant should avoid high impact exercises due to the risk of primary aim is to establish a sustained habit of regular physical
mechanical injury to their kidneys. activity. Incorporating forms of strength building exercises are
important for muscle function. Setting unrealistic targets is
• People with a fistula can exercise their fistula arm, but should not counterproductive as the person is unlikely to engage with a
apply weight to that area programme if they lack confidence and belief in their ability to
succeed, and failure is extremely demotivating. Therefore, to
effectively initiate and maintain exercise behaviour it is important
CKD specific contraindications
to work with the person and help them to:
1. Electrolyte abnormalities – especially hypo/hyperkalaemia
2. Recent ECG changes – especially symptomatic
tachyarrhythmias or brady-arrhythmias • understand the potential benefits of exercise in the context of
3. Excess inter-dialytic weight gain >4kg since last dialysis session their own health and lifestyle
4. Unstable dialysis treatment and titrating medication
5. Pulmonary congestions • assess and acknowledge perceived (e.g., time, motivation) and
objectives (e.g., co-morbidities) barriers to exercise
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 24 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 6:
Mental Health
• unhealthy diets • Consist typically of three sessions per week of moderate duration
• obesity (45 minutes to 1 hour) over 10 to 14 weeks (average 12 weeks)
• smoking
• diabetes
• hypertension Anxiety
• hyperlipidaemia
Anxiety is a noticeable, psychophysiological emotional state,
In most of these conditions lifestyle factors of physical activity characterized by feelings of apprehension, fear or expectations
plays an important role. of fear, worry, nervousness and physical sensations arising from
activation of the autonomic nervous system.1 It demonstrates
Prevention of depression with physical activity: Studies examining itself in a number of forms such as phobias, panic disorders and
whether physical activity might be protective against the risk of generalized anxiety disorder. It also appears as a symptom in many
depression later in life have shown promising positive effects. 4 different physical and mental illnesses. The normal human emotion
Evidence appears effective from childhood (9-15yrs) and lasting becomes pathological when it results in marked changes in
up to twenty years later. 5 It has also suggested the majority of thoughts and actions, occurring in the absence of an eliciting event
this protective effect was at low levels of activity and observed and when the response is disproportionate and unmanageable. 2
regardless of intensity. A large meta-analysis of all existing data
(49 independent studies of over quarter of a million people) Many studies have evaluated the effect of physical activity on
comparing onset of depression in non-active vs. active individuals anxiety reduction looking at both single bouts of exercise (state
also found that 1 hour of exercise could prevent incident cases of anxiety: how anxious an individual feels at the moment) and as a
depression by up to 17%. 6 result of regular training (trait anxiety: how anxious an individual
feels most of the time). Studies indicate that an acute or single
Treatment of depression with physical activity: There is some bout of exercise can yield a small but significant reduction in state
good evidence that regular moderate intensity physical activity is anxiety. 3, 4
effective in the acute treatment of mild to moderate depression
and in reducing depression in adult non-clinical populations. 7-9 For individuals with chronic anxiety disorders, regular physical
activity has a significant effect on the reduction of trait anxiety
Studies suggest that activity may alleviate depressive symptoms symptoms.1 It is also important to note that reviews comparing the
in the general population and also that depressive symptoms may effect of exercise to other treatments, 5, 6 consistently reported
be a barrier to activity, i.e. the relationship is bidirectional. 10 As for that exercise interventions work as least as effectively as standard
the most effective form of activity, moderate intensity exercise care treatment for anxiety and sometimes better. 6
is effective but low intensity exercise appears to have no effect.11
Recent meta-analysis of the adult population, suggested that This has important clinical relevance with the wider benefits of
moderate intensity physical activity interventions, aerobic activity, exercise on wellbeing and cardiovascular health. These studies
and if supervised by exercise professionals, can have a greater reinforce exercise as an important treatment option in people with
effect on major depressive disorders. 12, 13 In children and young anxiety/stress disorders either in conjunction, or as part of non-
adults (up to age 20) scientific evidence has been conflicting pharmacological alternative treatments. 1
regarding the protective effects of physical activity on depression.
However, meta-analysis has suggested a small significant positive
effect for physical activity on depression. 14 Post-traumatic stress disorder (PTSD)
Physical activity matched to an individual’s preferred intensity Post-traumatic stress disorder (PTSD) is a significant and
has also been shown to improve mental health outcomes and recognised form of anxiety based mental disorder, that is also
exercise adherence rates. 15 When preferred intensity exercise was associated with high rates of obesity and cardiometabolic
combined with motivational support it improved the reduction of diseases, partly thought to be due to reduced physical activity
depressive symptoms, quality of life and exercise adherence rates.16 levels. 1 - 4
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 25 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 6:
Mental Health
There are several reasons why PTSD may have an association with Most of these conditions are potentially open to modification by
reduced physical activity levels. Individuals with PTSD may limit physical activity.
their physical activity owing to a heightened concern for safety,
fear of bodily arousal symptoms, comorbid depression, substance A number of studies of people with schizophrenia have so far
use and insomnia. Reduced motivation, a lack of self-efficacy and shown a positive effect of physical activity on physical health,
social support will also contribute. 4,5 cardiometabolic factors, weight, quality of life, positive and
negative symptoms. 1,3,4 There is also some evidence that physical
To examine this association, physical activity levels trends, from activity can improve cognitive functioning among people with
20 years of data in the Nurse’s Health Study , were analysed. schizophrenia, particularly with increased exercise intervention. 4,5
Within this group, women who had suffered with a PTSD event, Increasing physical activity should therefore be advocated to all
were observed to have reduced physical activity levels following people with psychosis or schizophrenia. 6
the onset. 5 It was also noted that the more symptoms of PTSD
recorded, then the lower the level of subsequent physical activity. 5 NICE guideline CG 178 on Psychosis and Schizophrenia in adults:
treatment and management recommend: 7
• Before starting antipsychotic medication: an assessment of
nutritional status, diet and level of physical activity
• People with psychosis or schizophrenia, especially those taking
antipsychotics, should be offered a combined healthy eating and
physical activity programme by their mental healthcare provider
Sleep
Although research is very limited, the present evidence also Sleep consists of four formally recognised stages and has several
indicates that physical activity interventions are effective in features that comprise the totality of sleep. These stages and
reducing PTSD symptoms. 6, 7 However, at present, current features are used by everyone to recognise the quality and value
management of PTSD rarely incorporates physical activity as part of sleep 1, 4 (see table 1 on next page).
of its management.5
This has important clinical implications, the presence of PTSD Common sleep disorders include Insomnia and obstructive
symptoms should raise clinician concerns about the potential sleep apnoea
development of physical health problems and prompt close
attention to health behaviour. Physical activity can then be used as Insomnia
an adjunct, to normal accepted treatment as a means to improve Meta-analysis of sleep studies consistently show, small-to-
both the PTSD symptoms and the physical health of the individuals. moderate size benefits of both regular physical activity and acute
physical activity across multiple sleep outcomes; including total
sleep time, sleep efficiency, sleep onset latency, sleep quality and
Schizophrenia rapid eye movement sleep.5
Acute bouts of moderate to vigorous physical activity also
Poor physical health is often associated with severe mental illness reduce the time spent awake after falling asleep and shorten the
such as schizophrenia, depression and bipolar disorder. There time in stage 1 sleep.5 The relationship between physical activity
is a high risk of premature death and a shorter life expectancy and sleep appears consistent amongst the young, middle aged
of at least 10 years. 1 This excess cardiovascular mortality in men and older aged men and women.4
schizophrenia and bipolar disorder is attributed in part to the
increased modifiable coronary risk factors of: 1,2 Obstructive sleep apnoea
Moderate evidence exists associating physical activity with
• unhealthy diets significant improvements in apnoea hypopnoea index, reduced
• obesity daytime sleepiness and improved sleep efficiency of those with
• smoking obstructive sleep apnoea.4
• diabetes With its strong association with hypertension, heart failure,
• hypertension myocardial infarction, stroke, obesity and type 2 diabetes,
• hyperlipidaemia obstructive sleep apnoea is also dealt with in more detail in the
cardiovascular health section of this resource.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 26 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 6:
Mental Health
Sleep stages Sleep normally progresses through Wellbeing and quality of life
a series of four stages in repeated
cycles of about 90 minutes Many studies have shown improved wellbeing with physical
activity training. 1 Improved psychological wellbeing is also
Non-Rapid Eye Movement Stage N1 and N2, the two earliest the most common comment made on self-reported feedback
(NREM) - light sleep stages of sleep (except in infants), questionnaires. 1 Common wellbeing feelings, felt by people after
characterized by progressive physical activity are displayed in figure 1.
deepening sleep
Relaxed Satisfied Clear Minded
NREM slow wave sleep - Stage N3, deep sleep is characterised
deep sleep by slow brain activity and is associated Positive Calm Fitter
with memory consolidation. Maximal
in children and declines with age Worthwhile Alive Invigorated
Rapid Eye Movement Rapid Eye Movement sleep (REM) Good Healthy
sleep (REM) REM sleep is characterised by
episodes of rapid eye movement, Figure 1 - The Wellbeing feelings of Exercise
brain wave activation, lack of tone
in skeletal muscle and dreaming However, wellbeing concentrates largely on cognitive and
psychological feelings of our mental health and many studies on
Sleep outcomes and Definitions physical activity interventions, now research on the wider concept
behaviours of quality of life.
Sleep (onset) latency Length of time between going to Quality of life (QoL) “is a reflection of the way that individuals
bed and falling asleep perceive and react to their health status and to other, nonmedical
aspects of their lives”. 2 QoL is sometimes referred to as
Total sleep time (TST) Total time of actual sleep from the satisfaction with life. 3 QoL has a hierarchical structure with
sum of all stages domain-specific components under the umbrella of overall
QoL (Fig 2). One domain typically represents health related
Wake-time after Amount of time spent awake QoL (HRQoL) 4 this domain is often split further into further
sleep-onset (WASO) after sleep onset and before final sub-domains of physical health-related QoL and mental health-
awakening, usually in the morning related QoL. The other domain is non-health related QoL and not
discussed further in this resource.
Sleep efficiency The percentage of time of actual
sleep out of all the time sleeping The USA Physical activity guidelines examined the relationship
and trying to sleep between physical activity and QoL and concluded there was
strong evidence demonstrated for both adults and older adults
Table 1 – Components of sleep and Stages of sleep 4 that physical activity improves health-related quality of life when
compared with minimal or no-treatment controls. 5
This improved health-related quality of life from regular physical
activity can be expected to reduce health care costs from reduced
clinician appointments, medications and improved outcomes in
health. Even in the absence of disease, regular physical activity
should therefore be encouraged to all individuals to encourage
healthy ageing. 6
Occupational
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 27 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 6:
Mental Health
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 28 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 6:
Mental Health
In conclusion, it is presently thought that physical activity is At present, the recommendation stands that the elderly with
beneficial for brain function and may delay a decline in cognitive dementia engage in physical activity for their cardiovascular
function. “In spite of this link there is not yet sufficient scientific and cerebrovascular health, for the reduction in the incidence of
evidence that physical activity can reduce the risk of brain disease diabetes and obesity and for protection against frailty.
that causes dementia (e.g. Alzheimer’s disease)”. 24
Exercise as a fall prevention measure amongst the healthy elderly
If, however, physical activity at recommended levels is combined is well established, but recent meta-analyses also suggest that
with a number of other interventions, then there is the potential physical activity has a positive effect on the prevention of falls in
to delay or prevent a third of dementia cases. The interventions those with cognitive impairment 31, 32 and Parkinson’s disease.32
include: the active treatment of hypertension in the middle aged
(45-65 years); increased childhood education; the maintenance of NICE guideline NG9733 on Dementia focuses the guidance
social engagement; a reduction in smoking and the management on managing the risk of falling for people with dementia (in
of hearing loss, depression, diabetes and obesity. (see figure 2) community and inpatient settings) by using NICE guidance on falls
in older people (see next chapter of this guidebook).
Treatment of established dementia with physical activity: When using this guidance:
The results from random controlled exercise interventions to
improve cognitive and functional outcomes for this population • Take account of the additional support people living with
are also mixed, but there is evidence that exercise has no adverse dementia may need to participate effectively
effects and can lead to: 25-30
• Enhanced mobility • Be aware that multiple factorial falls interventions may not be
• An improved ability to perform daily functional activities suitable for a person living with severe dementia
• A reduction of the burden on family members
• A possible improvement in some elements of cognitive functioning
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 29 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 7:
Metabolic Health
Metabolic Syndrome However, a combination of the two has been seen to promote a
maximal benefit in people with obesity 3, 9, 10.
Metabolic syndrome is a cluster of factors including abdominal
obesity, insulin resistance, low HDL cholesterol levels, high plasma Physical activity and exercise recommendations for people
triglycerides and hypertension, which increase the risk of type with NAFLD
2 diabetes, cardiovascular disease, dementia and some forms Patients should aim to achieve at least 150 minutes each week of
of cancer. moderate exercise of ANY type and two strength training sessions
on non-consecutive days, for a minimum of 4 months to produce a
Regular physical activity has a beneficial effect on all these factors benefit in NAFLD, both with and without weight loss. Maintaining
and so may reduce the risk of these serious medical problems. a physical activity programme for 4 months is seen to significantly
improve metabolic parameters, more so than if exercise is halted
To prevent and treat, it is recommended to reduce sedentary time before the 4-month period 8.
and use moderate intensity exercise daily for a minimum of 30 but
preferably 60 minutes. 1
Polycystic Ovary Syndrome (PCOS)
Physical activity is proven to reduce the associated health
risks of metabolic syndrome even if individuals who exercise Polycystic ovary syndrome (PCOS) is a multifactorial condition
remain obese. 2, 3 This is a key point as both patients and health characterised by anovulation, hyperandrogenism and insulin
professionals are often over focused on weight and quickly resistance. Treatment thus needs to target both reproductive and
become demoralized if weight loss is not achieved. If physical metabolic outcomes.
activity is combined with sustained calorie restricted diet, then this
can support weight loss, nevertheless the primary objective is for Benefits of regular physical activity and exercise for women
physical activity to act on the pathophysiological factors leading with PCOS
to metabolic syndrome. Upon diagnosis, promotion of positive lifestyle behaviour patterns
is regarded as a first-line therapy. Regular physical activity
improves markers of cardiorespiratory fitness, body composition
Non-Alcoholic Fatty Liver Disease (NAFLD) and insulin resistance in people with PCOS 1. The benefits of
lifestyle intervention in those who are also overweight and obese is
Non-Alcoholic Fatty Liver Disease (NAFLD) is associated with often independent of significant weight loss 2.
an increased risk of insulin resistance, metabolic syndrome
and cardiovascular disease. The development of NAFLD and The effects of increased physical activity can be assessed in
progression to non-alcoholic steatohepatitis (NASH) is partly due relation to metabolic and cardiorespiratory function. Insulin
to a high level of sedentary behaviour 1. resistance, a hallmark of PCOS, is present in 60–80% and
increases to 95% in those who are obese 3-5. Insulin resistance
Benefits of regular physical activity and exercise for people is often independent of body weight, although is exacerbated
with NAFLD by the presence of concomitant obesity 6. Recent meta-analyses
There is a common consensus that an increase in physical activity conclude that vigorous physical activity can directly improve
of any type will improve outcomes in people with NAFLD. However, insulin resistance and cardiorespiratory fitness in women
exercise-based NAFLD studies are limited with small sample sizes with PCOS.
and large variations 2, 3. A recent analysis by the National Health and
Nutrition Examination Survey (NHANES) database concluded that The evidence for the beneficial impact of physical activity on
for every 10 minutes of physical activity, the overall mortality risk reproductive and cutaneous outcomes i.e. hirsutism, is more
was reduced by 7% in individuals with NAFLD 3, 4. limited. Nevertheless, increased physical activity is reported to
have a beneficial effect on reproductive hormones 7, ovulation 8
A meta-analysis of 20 randomised controlled trials, involving and menstrual regularity 9,10. Importantly, increased exercise and
more than 1000 individuals, showed that exercise alone can dietary modification have both been reported to improve free
promote beneficial effects in those with NAFLD, even in the androgen index (FAI) and hirsutism (measured via Ferriman-
absence of weight loss 5. Independent of dietary intervention, an Gallway score) 11. However, the data on any direct effects of
8-week web-based intervention reported no reduction in weight physical activity on hirsutism are limited, with studies to date
but significantly improved liver enzymes, including ALT and reporting either little to no effect 12,13 , or modest improvements
the surrogate fibrogenesis marker pro-collagen-3 (PRO-C3)6. only 14. It is known that insulin levels can modulate hirsutism
Secondary complications, including hepatic inflammation and in PCOS 15, therefore improvements in insulin resistance may
fibrosis, also showed marked improvements that were maintained ultimately yield benefit.
after exercise had been discontinued 2, 6.
Regular exercise alone may also improve mental health, physical,
The leading cause of death in people with NAFLD is associated general and social functioning by 10% 16.
with cardiometabolic function rather than liver related
complications 7. Marginal differences exist when comparing the
beneficial impact of aerobic and resistance exercise on liver
enzymes, metabolic parameters and hepatic steatosis 8.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 30 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 7:
Metabolic Health
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 31 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 7:
Metabolic Health
Sessions should target a range of muscle groups (8-10 different A reduction in basal and/or prandial insulin dose may be
exercises) and completion of 1-3 sets of 10-15 repetitions to near required around exercise to prevent (possible) hypoglycaemia
fatigue is appropriate 14,21-22. 14
. Irrespective, it is important to guide patients to recognise the
symptoms of hypoglycaemia and how to self-monitor.
The beneficial effects of each acute exercise session on glycaemic
control are short lived (24-48 hours) and thus frequency of NICE guidelines PH38 26 Type 2 diabetes - prevention in people
exercise is of key importance. Daily exercise is considered optimal at high risk recommend:
for maintaining good glycaemic control, but if this is not possible, • Give information about increasing physical activity and
then aiming for no more than two consecutive days without reducing the amount of time spent being sedentary
exercise is sufficient 14. • Consider referring those who want structured or supervised
exercise to an exercise referral scheme or supervised exercise
Prolonged periods of inactivity are known to be detrimental sessions, as part of an intensive lifestyle-change programme
to glycaemic control and metabolic health 14,21. In addition to • At least once a year, review the lifestyle changes made by
performing regular structured exercise, it is also recommended those at high risk
that people with prediabetes and type 2 diabetes decrease time • Raise awareness of importance of physical activity
spent in sedentary activities 14, 21,22. Any periods of prolonged sitting • Help individuals to find other ways to identify and overcome
(e.g. desk working) should be broken every 30 mins with short any barriers to physical activity
periods (3-5 mins) of light-moderate physical activity such as
walking or stretching 14, 21. Contraindications
• Uncontrolled blood glucose of >14 mmol or <6 mmol/l, which
should be corrected first 27
Adverse cardiovascular event: There is a small potential health risk • Vigorous exercise is contraindicated in those with
of physical activity (e.g. adverse cardiac events) for people with proliferative retinopathy 27
prediabetes or type 2 diabetes, but the risk is low and maintaining
an inactive/sedentary lifestyle is associated with greater risk over
the long term 14, 21.
Type 1 diabetes
For the vast majority of people with prediabetes or type 2
diabetes, who have no symptoms of underlying cardiovascular Introduction
disease or coronary ischemia, the risk of participating in low- Regular physical activity confers many health benefits in people
to moderate-intensity physical activity (i.e. not exceeding the with type 1 diabetes 1,2, with improvements noted in blood
demands of brisk walking) is low and medical clearance is not glucose, insulin sensitivity, lipid profiles, mental wellbeing, body
necessary 14, 21. composition and physical fitness 1,3,4. Accordingly, organisations
endorse exercise as a key component of the treatment plan of
For middle aged or older individuals with prediabetes or type 2 type 1 diabetes 5–8. However, many individuals with type 1 diabetes
diabetes, who wish to take part in more strenuous or prolonged struggle to achieve the recommended physical activity levels 4,
exercise (e.g. competitive racing, HIIT etc.), then assessment for with fears around hypoglycaemia and loss of glycaemic control
underlying conditions that may increase the risk of an adverse reported as major barriers to frequent exercise participation 9, 10 .
event is recommended 14, 21. This should include consideration of Educational support centred around nutritional and insulin therapy
signs and symptoms of myocardial ischemia, including chest-pain, strategies that seek to manage these concerns help foster safe
severe shortness of breath upon exertion and/or syncope, and a exercise performance and garner the physical and mental benefits
potential referral for a resting/ exercise ECG in any individual who of being regularly active 1.
is symptomatic 14, 21.
Current recommendations for physical activity and exercise
Foot care and exercise: Peripheral neuropathy is a feature of Adults with type 1 diabetes should be encouraged to engage in at
type 2 diabetes. People with severe peripheral neuropathy should least 150 minutes of moderate-to-vigorous intensity
thoroughly check their feet on a daily basis, especially (~40-59% VO2max) aerobic exercise (e.g. jogging, cycling, walking,
if they are planning to exercise, and appropriate footwear should swimming etc) per week 7, 11. Ideally, exercise should be spread
be worn 14, 21. Moderate intensity weight bearing activity can be over 3 days per week with activity breaks of no more than 2
participated in safely, provided there are no active ulcerations 14, 21. consecutive days. Shorter durations (minimum 75 minutes per
week) of vigorous-intensity exercise or interval training may
Interactions with medications: Hypoglycaemia rarely occurs be suitable for younger and/or more physically fit individuals.
with type 2 diabetes controlled with dietary adjustment or Additionally, muscle strengthening activities can be performed 2-3
with common diabetes medications, including metformin, times per week on non-consecutive days with additional flexibility
thiazolindinediones, glucagon-like peptides and SGLT inhibitors. sessions to support joint range of movement.
In general, the American Diabetes Association do not recommend
adjustment of the dose of medication when taking up exercise 14.
If treated with insulin alone, or in combination with medications
such as sulfonylureas, then hypoglycaemia may be more likely and
blood glucose should be monitored carefully 14.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 32 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 7:
Metabolic Health
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 33 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 7:
Metabolic Health
• Insulin therapy adjustments to manage blood glucose Manging hyperglycaemia: Very intense activities (sprinting,
Managing hypoglycaemia: In general, aerobic exercise lowers resistance exercise) may result in a small rise in blood glucose
blood glucose levels and hypoglycaemia is likely if the activity concentrations 32. For these activities, a reduction in bolus insulin
is performed in the postprandial phase with no adjustment to prior to exercise may not be needed 7, though careful glucose
pre-exercise bolus insulin dose 27. For mild to moderate intensity monitoring during exercise is still required. If exercise-induced
aerobic activities lasting 30-60 minutes when circulating insulin hyperglycaemia occurs, a small bolus insulin dose immediately after
concentrations are low (i.e. fasted or basal concentrations), exercise can help reduce blood glucose to euglycaemic levels 33.
consuming 10-15g of carbohydrates without a bolus insulin
dose reduction before exercise may be sufficient to avoid Alternatively, performing aerobic exercise after resistance/
hypoglycaemia 28. For both, multiple daily injections (MDI) and strengthening exercise may help lower glucose levels 34,35.
continuous subcutaneous insulin infusion (CSII) users, bolus A summary of the recommended bolus insulin dose alterations
insulin should be reduced by 25-50% for activities lasting 30-45 around exercise for people with type 1 diabetes can be found in
minutes, with larger dose reductions of 50-75% advised when Table 2.
exercise exceeds 45 minutes 5.
• Carbohydrate ingestion
Mixed activities (interval training and team/individual sports) Carbohydrate intake will vary depending on the exercise
typically result in more stable glucose levels than those characteristics (modality, timing, intensity) and on-board insulin
associated with aerobic exercise 22, 29. For these activities, the levels. Current recommendations suggest ingesting an upper
pre-exercise bolus insulin dose should be reduced by ~25% when limit of 0.5-1.0 g of carbohydrate per kg body mass per planned
exercise lasts for 30-45 minutes and by ~50% when exercise hour of exercise 5. Consuming a small carbohydrate-based snack
surpasses 45 minutes 5 . (0.4 grams of carbohydrates per kg body mass) before bed may
also help lower the risk of glycaemic declines after exercise 18,19,27.
For individuals on MDI, a 20% dose reduction in basal insulin
on the day of exercise may help avoid hypoglycaemia 19. For • Blood glucose monitoring
individuals on CSII a reduction 30 or suspension 31, in basal insulin Increased frequency of self-monitoring of blood glucose can
delivery 30-60 minutes before exercise can reduce the risk of lower the risk of hypoglycaemia 36. Use of continuous glucose
hypoglycaemia. monitoring devices provides another option to obtain glucose
readings through implantable interstitial glucose sensors 37, 38
Due to increases in tissue sensitivity to insulin, the risk of However, whilst these devices are convenient to monitor glucose
hypoglycaemia remains high for many hours after exercise. around exercise, they often fail to accurately report readings
Frequent blood glucose monitoring is key in detecting and when glucose is changing rapidly or when levels deviate from
preventing later onset hypoglycaemia. A low glycaemic index, the euglycaemic range 39. As such, caution should be taken
carbohydrate-rich meal alongside a 50% dose reduction in bolus when using them during exercise and clinical decision making
insulin can minimise glycaemic fluctuations as well as protect should always be based on blood glucose levels.
against post exercise and/or nocturnal hypoglycaemia 18, 27.
Conclusion
For CSII users, reducing basal insulin delivery rates for up to Regular physical activity and exercise is considered a cornerstone
12 hours post-exercise may be necessary to avoid later onset for the clinical management of type 1 diabetes. Each person’s
hypoglycaemia. response to exercise may be different, but prudent adjustments in
exogenous insulin dosing and carbohydrate intake around exercise
can help develop an individualised glucose management strategy
that assists them in achieving their exercising goals.
Table 2: Suggested initial pre-exercise meal bolus insulin dose reduction for activities started within 90 minutes of insulin administration
Taken from Physical Activity/Exercise and Diabetes: A Position Statement of the American Diabetes Association 7. NA,
not assessed as exercise intensity is too high to sustain for 60 minutes.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 34 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 8:
Musculoskeletal Health
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 35 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 8:
Musculoskeletal Health
• A combination of exercise types, for example balance, flexibility, Historically, a major barrier to physical activity in RA was advice by
stretching, endurance and progressive strengthening exercises. clinicians to rest rather than exercise. However, a myriad of studies
support the incorporation of exercise training programs to help
Contraindications improve aerobic fitness, muscle strength and overall cardiovascular
Acute illness with pain and general deteriation health without aggravating disease activity or joint integrity6–8.
Avoid high impact activities or those with a high risk of falling29 Thus, RA patients should be encouraged to take part in regular
physical activity including aerobic training (to improve aerobic fitness
and reduce cardiovascular disease risk), resistance exercise (to
Rheumatoid Arthritis improve muscle strength) and flexibility (to improve range of motion).
4) Some people may present with swollen and tender joints in the
hands and wrist. It is advisable to use support bandages/braces.
If pain is severe, consider advising the person to perform
exercises utilising unaffected joints 10.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 36 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 8:
Musculoskeletal Health
Prevention of falls and fracture 1) Exercise programmes should aim to provide a high
challenge to balance
Older people, with or without co-morbidities, often experience 7) Strength training may be included in addition to balance training
diminishing muscle function and/or coexisting pain which limits
their daily activity and increase the risk of a fall and fracture. Yet 8) Exercise providers should make referrals for other risk factors
untargeted physical activity, such as walking and cycling, is not to be addressed
shown to have any effect on the risk of falls.1
9) Exercise as a single intervention may prevent falls in people with
However, the available evidence is that group and home based Parkinson’s disease or cognitive impairment. There is currently
programmes with muscle strengthening and balance reduce no evidence that exercise as a single intervention prevents falls
both the rate of falls and the risk of falling. 4,5 Different forms of in stroke survivors or people recently discharged from hospital.
exercise have different results. Exercise interventions of all types v Exercise should be delivered to those groups by providers with
controls reduce the rate of falls by 23%,6 whilst targeted exercise particular expertise.
programmes with multiple types of exercise (balance, functional
exercise plus resistance exercise) probably reduce falls by 34%.6
Tai Chi may also reduce the risk of falling by 19%6 and exercise NICE guideline CG161 on Falls in older people: assessing risk
interventions may reduce the risk of a falls related fracture.4,6 and prevention recommends:9
Although most evidence on fall prevention has been with cognitively • Multifactorial interventions with an exercise component are
healthy elderly people, recent evidence supports the evidence that recommended for older people in extended care settings who
physical activity also has a positive effect in the prevention of falls in are at risk of falling
the elderly with cognitive impairment and Parkinson’s disease 5,7
Strength and balance training may need to precede walking • A muscle-strengthening and balance programme should
exercise to make the physical activity possible. In older people two be offered
decades’ worth of strength and muscle mass loss can be regained
by just two months of strength training.8 • This should be individually prescribed and monitored by
an appropriately trained professional
The optimum characteristics of an exercise intervention for falls
prevention are as follows:5 • There is no evidence that brisk walking alone reduces the risk
of falling; however, there may be other health benefits of brisk
walking by older people#
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 37 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 9:
Obesity
Overweight and obesity are defined as ‘abnormal or excessive There is little evidence that resistance training alone produces
fat accumulation that may impair health’.1 Using Body Mass Index any significant weight loss.11 However, resistance strength training
(weight (kg) / height2 (m)) (BMI) overweight is classified as a BMI has also been shown to maintain overall health, muscle strength
of 25-30 and obesity as >30. (preventing loss of skeletal muscle mass), preserve bone strength
14
and reduce mortality in men.9,15
Obesity is a major risk factor for many non-communicable
diseases (NCD) such as:1 The real health message of physical activity in obesity: It is very
important to stress that aerobic physical activity offers substantial
• Cardiovascular disease (mainly heart disease and stroke) health benefits even if weight loss is not achieved,10 as people
• Diabetes often have unrealistic weight loss expectations.16 However, weight
• Musculoskeletal disease (mainly osteoarthritis) loss is still recommended in obese people to reduce the risk of
• Some cancers (mainly colon and breast)2 non-communicable diseases and premature death.5, 6
Childhood obesity is associated with a higher chance of obesity, Many trials of exercise therapy have reported little or no weight
premature death 2 and disability in adulthood.1,2 However, in addition loss (<5kgs) but still have reported many health benefits
to future risks,3 childhood obesity is associated with considerable including:10
emotional and behavioural problems including in boys, conduct
problems, hyperactivity and inattention problems, peer relationship • Improved vascular endothelial function17
problems, prosocial behaviours and total social difficulties.4 • Lipoprotein particle size18
• Reduction in low density lipoprotein18
Mild weight loss in obesity, has been associated with • Reduction in triglycerides10
improvements in most cardiometabolic factors,5 whilst significant • Improved cardiovascular fitness19
weight loss (>5% of baseline weight) has been shown to be more • Lower diastolic blood pressure10
effective in reducing cardiac and diabetic risk factors, and even • Improved glucose control
death rates.6,7 • Quality of life20,21
Physical activity and increased intensity: Significant weight loss • Increased aerobic capacity (6-3 ml/kg/min, p<0.01)
can occur with aerobic exercise without calorific restriction, but it • Decreased systolic blood pressure (-6 mm Hg, p<0.05)
requires a high exercise volume of >225 minutes a week. For the • Decreased diastolic blood pressure (-3.9 mm Hg, p<0.01)
majority, these levels may not be practical or achievable.12 • Decreased waist circumference (-3.7 cm, p<0.01)
• Decreased resting pulse (-4.8 bpm, p<0.001)
Physical activity and prevention of weight gain: To prevent
the shift from normal weight to overweight and obesity, it is In addition, these individuals experienced an increase in positive
recommended that levels of 150-250 min/week of moderate to mood with acute exercise.
vigorous physical activity are required.12
Advice to obese individuals must be realistic as they are often
Physical activity and weight maintenance: After successful weight unfit and have coexisting co-morbidities present. You need to be
loss, physical activity levels of 200-300 min/week should be aware of the effort required to lose weight, what is a reasonable
maintained to avoid regaining weight.12 NICE guidelines suggest expectation of weight loss and of the stigma people feel being
even higher levels of 300-450 min/week.13 labelled overweight or obese.23
Aerobic exercise or resistance training and weight loss: Aerobic Small steps in gained activity through everyday changes should be
exercise is most beneficial by virtue of energy expenditure and encouraged and maintained even if more formal physical activity
health benefits of important risk factors.11 remains difficult. See Sedentary behaviour later in this booklet.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 38 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 9:
Obesity
Guidance on managing the overweight and obese has been • Encourage children to do at least 60 minutes of moderate or
summarized in NICE guidelines and the areas relative to physical greater intensity physical activity each day. Tips include:
activity are listed below.
• Can be split into several sessions
NICE clinical guideline CG 189 on managing overweight and
obesity in adults recommends: 13 • Awareness that children already obese may need to do
more than 60 min/day
• Encourage adults to increase their level of physical activity even
if they do not lose weight as a result, because of the other health • The activity can be in 1 session or several sessions
benefits it can bring (for example, reduced incidence of type 2 lasting 10 minutes or more
diabetes and cardiovascular disease).
• Encourage children to reduce inactive behaviours, such as
• Encourage adults to do at least 30 minutes of moderate or sitting and watching television or playing video games
greater intensity physical activity on 5 or more days a week. The
activity can be in 1 session or several lasting 10 minutes or more. • Give children the opportunity and support to do more
exercise in their daily lives
• Advise that to prevent obesity most people have to do 45-60
minutes/day of moderate-intensity exercise particularly if they do not • Give children the opportunity and support to do more
reduce their energy intake. Advise people who have been obese and regular, structured physical activity
lost weight that they may need to do 60-90 minutes/day of moderate-
intensity physical activity to avoid regaining weight once lost. • Make the choice of activity with the child, and ensure it
is appropriate to the child’s ability and confidence
• Encourage adults to build up to the recommended activity levels
for weight maintenance, using a managed approach with agreed
goals. Recommend types of physical activity, including: Summary
• No strong evidence that physical activity of 150 minutes a
• Activities that can be incorporated into everyday life, such as week, on its own achieves any significant weight loss
brisk walking, gardening or cycling • High levels of physical activity are required to lose weight
alone without dietary changes
• Supervised exercise programmes • 45-60 minutes/day of moderate-intensity physical activity are
required to prevent weight gain
• Other activities, such as swimming, aiming to walk a certain • 60-90 minutes/day of moderate-intensity physical activity are
number of steps each day, or stair climbing needed to avoid regaining weight once lost
• Weight loss with physical activity is best when combined with
• Take into account the person’s current physical fitness and ability dietary & behavioral interventions
for all activities. Encourage people to also reduce the amount
of time they spend inactive, such as watching television, using a Adults, who find it difficult to maintain their weight, should be
computer or playing video games. encouraged to:
• Reduce energy intake
• Minimise sedentary behavior
NICE clinical guideline CG 189 on managing overweight and
• Work on progressively increasing their physical activity,
obesity in children recommend: 13
initially up to and then past 30 minutes and up to 60 minutes
a day or more.
• Encourage children and young people to increase their level of • Aerobic physical activity offers substantial health benefits
physical activity, even if they do not lose weight because of the even if weight loss is not achieved
reduced risk of type 2 diabetes and cardiovascular disease.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 39 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 10:
Pregnant women may be concerned that physical activity is not safe, Pre-Activity Evaluation
however, there is no evidence suggesting adverse maternal or infant
outcomes for healthy women resulting from moderate intensity Most pregnant women can safely partake in physical activity.
physical activity. Instead, pregnancy offers an ideal opportunity to There are very few absolute contraindications to moderate-
adopt a healthy lifestyle, with the increased motivation to self-care vigorous physical activity (MVPA) during pregnancy and these
coupled with frequent access to maternity services. are mostly related to the pregnancy itself e.g. intrauterine growth
restriction or presence of pre-eclampsia. However, there are a
Physical activity can be safely recommended during and after number of medical conditions where women need to be cautious
pregnancy. UK Chief Medical Officers recommend that pregnant and discussed with her obstetric healthcare professional8 (box 1).
woman aim for at least 150 minutes of moderate physical activity Here individualized exercise programmes may be needed.
every week and strength conditioning exercises twice a week. It is
important to highlight to woman that ‘every activity counts’ and
that they should always ‘listen to your body and adapt’ what they Box 1: Absolute Contraindications to Moderate-Vigorous
do accordingly. Physical Activity (MVPA) in Pregnancy8, however, activities of
daily living should still be continued.
Risk Management
There are clear benefits for both mother and baby. Outside the conditions listed, there is no evidence that there is an
increased risk of complications for the mother or the baby if the
Key Benefits of Physical Activity During Pregnancy 1-5 woman is physically active during her pregnancy; however, there
are a few activities not recommended (box 2).2, 5
• Reduction in hypertensive disorders
• Improved cardiorespiratory fitness
• Lower gestational weight gain Hyperthermia
• Reduction in risk of developing gestational diabetes (>39.2°C): During the first trimester in particular, hyperthermia
can increase the risk of developmental problems (e.g. spina
Further low – moderate quality evidence exists for the woman bifida). There is no evidence that becoming slightly warm during
with reduced: 4-7 physical activity can cause this, however, the woman should be
• Pelvic and low back pain advised to not become uncomfortably hot. Keeping hydrated
• Pre-natal depression will help.2, 5
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 40 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 10:
• Contact sports e.g. rugby, soccer, boxing, basketball and As with any physical activity advice, consider the woman’s activity
martial arts history and preferences. During the first trimester morning
• Sports where there is a risk of falling e.g. riding, skiing, sickness and fatigue may limit activity ability, but most women will
off road cycling, gymnastics and horse riding naturally reduce the intensity as it becomes more challenging.
• Scuba diving
• Sky diving FREQUENCY – most days of the week for aerobic work and twice
• Exercising at high altitude (>6000 feet) weekly women should perform 8 -12 repetitions of strengthening
• Exercising in hot temperatures (including ‘hot yoga’ activities of all major muscle groups.
or ‘hot Pilates’ )
INTENSITY – moderate; which is an activity that makes you to feel
After first trimester: warmer and breath faster but still be able to hold a conversation.
• Sports where there is a risk of being hit in the abdomen by Those women who are training more seriously may be used to
equipment e.g. tennis, squash monitoring their heart rate in which case they should be advised
• Avoid exercising lying flat on your back after 16/40 due to to work at 50% - 70% of their heart rate max. However, there is
venous compression and hypotension no indication for someone to start monitoring their heart rate just
because they are pregnant.
Modifications and Considerations: 2 TIME – aim to accumulate at least 150 minutes of moderate intensity
physical activity every week. Recent evidence has shown that there
Due to the production of relaxin, ligaments around the spine, hips is no minimum amount of physical activity required to achieve some
and pelvis will soften in preparation for delivery which may slightly health benefits, with some activity being better than none.
increase the risk of injury. Stability exercises (e.g. Pilates – as long
as it is modified for pregnancy by an experienced instructor) will TYPE – examples of activities and exercise that have been found
help to manage this. Also, this softening will effectively increase a to be safe and beneficial in pregnancy2:
woman’s flexibility so to protect their joints they should not stretch
beyond their normal range. • Walking
• Stationary cycling
Avoid exercising lying flat on back or standing still for long • Dancing
periods after 16/40 weeks due to venous compression and • Aerobic exercises (inform the instructor)
hypotension2. • Resistance exercises (e.g. Using weights, elastic bands)
• Stretching - Yoga / Pilates – beware not lying flat on the
The combination of increasing lumbar lordosis and weight puts back after 16/40
more strain on the joints, especially in the back and pelvis. In • Swimming / hydrotherapy water aerobics (water temp
addition, as the pregnancy progresses, stress incontinence will not >32deg)
become more likely (prevalence 32-64% 9). Stability and pelvic
floor exercises will help to protect against this; pelvic girdle pain
is not an inevitability during pregnancy (prevalence 50-70% 10), Advice to a pregnant woman who is new to physical activity:
but can be managed with prompt identification, assessment and
treatment by a physiotherapist 10, 11. As the woman progresses Women who have been sedentary are advised to start a gradual
through the second and third trimesters they should reduce the progression of physical activity – ‘not active – start gradually’
amount of any weights they are lifting. and build up to 30 minutes on most days at a moderate intensity.
Vigorous activity is not recommended for previous inactive
When to stop exercising:2 women. Strengthening exercises twice a week are
also recommended.
Advise to stop if there is:
Walking is a good way to start. Once they are used to doing some
• Vaginal bleeding walking on a regular basis they can add in other types of activity.
• Abdominal pain Women should also be advised to avoid prolonged periods of
• Regular painful contractions sitting and breaking up sedentary time with at least light physical
• Amniotic fluid leakage activity. It is also important to highlight that every activity counts
• Dyspnoea before exertion and women should ‘listen to their body and adapt’ what they
• Persistent excessive shortness of breath that does do accordingly.
not resolve with rest
• Dizziness
• Headache
• Chest pain
• Muscle weakness affecting balance
• Calf pain or swelling
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 41 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 10:
t
1. No evidence of harm
ou
Pregnant women may be concerned that physical activity is not
Le
ab
safe, however, there is no evidence suggesting adverse maternal
isu
aim for
nd
or infant outcomes for healthy women resulting from moderate at least
re
ta
150
intensity physical activity, indeed there are clear benefits.
Ou
2. Listen to your body and adapt
Some activities may feel different due to physiological changes
and may require adaptation as pregnancy progresses. A general minutes
rule is if it feels comfortable keep going, if it is uncomfortable of moderate intensity activity
stop and seek advice. every week
Build
3. Don’t bump the bump Start back up
pelvic floor to muscle
Certain activities may represent an increased risk of injury through exercises as strengthening
physical contact. Therefore, avoid contact sports and activities soon as you can activities twice
Exercise in pregnancy
• Pregnant women should be informed that beginning or
continuing a moderate course of exercise during pregnancy is The benefits of physical activity after pregnancy
not associated with adverse outcomes. It helps recovery and improves physical and mental health.
Evidence is demonstrating that physical activity:14
• Pregnant women should be informed of the potential dangers of • Reduces depression
certain activities during pregnancy, for example, contact sports, • Improves emotional wellbeing
highimpact sports and vigorous racquet sports that may involve • Improved physical conditioning
the risk of abdominal trauma, falls or excessive joint stress, and • Reduces postpartum weight gain and a faster return
scuba diving, which may result in fetal birth defects and fetal to pre-pregnancy weight.
decompression disease.
The evidence is also strong for pelvic floor muscle training in
the treatment of urinary incontinence in the general postpartum
Physical activity after pregnancy population.15
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 42 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 10:
3. If a woman was active before, encourage a gradual reintroduction If a woman experiences any of the signs and symptoms of pelvic floor
of physical activities. However, emphasise that they may need and/or abdominal wall dysfunction, more intense physical activity
to change or adapt the type of activity undertaken initially. For should not be resumed, and referral to a specialist pelvic health
example, returning to contact sports gradually and slowly building physiotherapist is required.19
up muscle tone and aerobic fitness. Pelvic floor exercises should be
discussed, encouraged and should be continued daily. • Urinary and/or faecal incontinence
• Urinary and/or faecal urgency that is difficult to defer
4. Women can also be reassured that moderate physical activity has • Heaviness/pressure/bulge/dragging in the pelvic area
no negative impact on breast feeding postpartum.13, 14 • Pain with intercourse
• Obstructive defecation
• Pendular abdomen, separated abdominal muscles and/or decreased
What about vigorous intensity activity? abdominal strength and function
• Profound physical and physiological changes accompany • Musculoskeletal lumbopelvic pain
pregnancy 16 and subsequently tissue healing following child birth
is understood to take 4-6 months17.For instance, running can cause
sudden rises in intra-abdominal pressures18 increasing the risk of Take home messages:
pelvic floor dysfunction, such as urinary incontinence, pelvic organ
prolapse, abdominal weaknesses and lumbopelvic pain. Guidelines Physical activity is an important part of any management for a woman
on returning to running safely postnatally, relate to all vigorous who is pregnant, leading to:
activity and recommend building up pelvic floor and abdominal • Reduction in hypertensive disorders
strength, alongside moderate intensity physical activities in the • Improved cardiorespiratory fitness
first three months.19 • Lower gestational weight gain
• Reduction in risk of developing gestational diabetes
• After having built up moderate intense physical activities over a • There is no evidence of harm when healthy pregnant or postnatal
minimum period of three months and in the absence of any signs women participate in moderate intensity physical activity
or symptoms pf pelvic floor or abdominal wall dysfunction, more • Keeping active in pregnancy could improve health outcomes for
intense activities, such as running , can gradually resume. both mother and baby
• Pregnancy offers an ideal opportunity to adopt a healthy lifestyle,
with the increased motivation to self-care coupled with frequent
access to maternity services
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 43 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 11:
Respiratory Disease
Asthma is a common condition that affects people of all ages. Chronic obstructive pulmonary disease (COPD) results in
Respiratory symptoms, such as intermittent recurrent dyspnoea irreversible damage to lung tissue and long-term inflammation
and wheeze and variable expiratory airflow limitation are a of the airways, resulting in fixed airflow limitation. As COPD
result of increased airways hyper-responsiveness and progresses, symptoms such as breathlessness and muscle fatigue
airway inflammation. make exercise an unpleasant experience, which, together with a
sedentary lifestyle , leads to muscle deconditioning associated
Regular exercise is recommended as supplementary therapy with reduced physical activity. This subsequently contributes
to medication in people with stable asthma1. The key benefits to further decline in exercise capacity and perception of
of exercise training in people with asthma are improved cardio- breathlessness. Thus, people with COPD get trapped in a vicious
respiratory fitness and increased exercise capacity1-3. cycle of declining physical activity and increasing symptoms of
breathlessness during exercise 1.
In some individuals, regular exercise may also improve resting
lung function1, 3, asthma control and quality of life 1. While growing You feel
breathless
evidence suggests that obesity increases the risk of asthma4,5,
the benefits of weight loss for asthma control remain uncertain6.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 44 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 11:
Respiratory Disease
Further, the British Thoracic Society guidelines on pulmonary • Advise people of the benefits of pulmonary rehabilitation and the
rehabilitation include COPD sufferers with a MRC dyspnoea grade commitment needed to gain these.
of 2 who are functionally limited by breathlessness 6. However,
physical activity should be considered an integral part of the
Contraindications
clinical management of all people with COPD, irrespective of Pulmonary rehabilitation is not suitable for people who are
their MRC score. 1, 7. unable to walk, who have unstable angina or who have had a
recent myocardial infarction 5
Grade Degree of breathlessness related to activities
Cystic Fibrosis
1 Not troubled by breathlessness except on strenuous exercise
General
Exercise The progressive respiratory dysfunction associated with cystic
Advice fibrosis (CF) leads to fixed airways obstruction, abnormal
2 Short of breath when hurrying or walking up a slight hill
ventilatory responses and subsequent breathlessness during
Consider exercise, which limits exercise capacity and the ability to perform
3 Walks slower than contemporaries on level ground referral to
activities of daily living. Low levels of physical activity contribute to
Pulmonary
because of breathlessness, or has to stop for breath when Rehab disease progression in CF 1. Further, lower levels of aerobic fitness
walking at own pace are associated with a reduced life expectancy 2.
4 Stops for breath after walking about 100 metres or after a few
Exercise is an important adjunct to treatment for people with CF,
minutes on level ground
irrespective of age and disease severity 3. While evidence for the
5 Too breathless to leave the house, or breathless when dressing efficacy of exercise training in CF is relatively limited 4, regular
or undressing exercise and physical activity may provide a wide range
of benefits, including:
• Increased exercise capacity
NICE guidelines CG101 recommend:5 • Improved strength and endurance of the muscles
of ventilation
• Make pulmonary rehabilitation available to all appropriate • Reduced breathlessness
people with COPD, including people who have had a recent • Preserved pulmonary function
hospitalisation for an acute exacerbation; • Enhanced mucus clearance
• Offer pulmonary rehabilitation to all people who view NICE guidelines NG78 make the following recommendations 5:
themselves as functionally disabled by COPD • Advise people with CF and their family members or carers
(usually MRC grade 3 and above); (as appropriate) that regular exercise improves both lung
function and overall fitness;
• For pulmonary rehabilitation to be effective, and to improve • Offer people with CF an individualised exercise programme,
adherence, they should be held at times that suit people, in taking into account their capability and preferences;
buildings that are easy to get to and that have good access for • Regularly review exercise programmes to monitor the
people with disabilities; person’s progress and ensure that the programme continues
to be appropriate for their needs;
• Pulmonary rehabilitation programmes should include • Provide people with CF who are having inpatient care with:
multicomponent, multidisciplinary interventions that are tailored - an assessment of their exercise capacity;
to the individual person’s needs. The rehabilitation process should - the facilities and support to continue their exercise
incorporate a programme of physical training, disease education, programme (as appropriate), taking into account the
and nutritional, psychological and behavioural intervention; need to prevent cross-infection and local infection
control guidelines.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 45 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 12:
Perioperative Surgery
The perioperative period includes the time before, during and that may predispose them to post-operative complications after
after surgery. The evidence for physical activity and health is well surgery, delayed discharge and surgical survival rates.2,3
established across many areas which may prevent or affect surgery:1
It has been shown that poor preoperative physical performance
• All-cause mortality – 30% risk reduction comparing most increases the risk of complications after major non cardiac surgery
active with least active 4,5
and prolongs recovery after abdominal surgery. 6 There is also
strong evidence that if cardiorespiratory fitness (CRF) is measured
• Risk reduction of hip fracture is up to 68% at the highest level preoperatively, it is predictive of complications in the postoperative
of activity period in several settings.7-13
• Lower risk of falls and fractures in elderly patients who regularly The assessment of CRF preoperatively has been shown to offer
participate in physical activity significant advantage when compared to age alone in predicting
mortality after major surgery.14 This same study also showed firstly:
• Colon cancer – 30% lower risk in those who are active CRF to be a significant independent predictor of length of stay
in hospital with patients older than 75 and secondly, a low CRF
• Breast cancer – 20% lower risk in those who are active associated with a median of 11 days longer in hospital and 2 days
longer in critical care.14
• Cardiovascular disease – 20-35% lower risk of cardiovascular
disease, coronary heart disease and stroke Another study of pre-operative fitness and outcomes after major
abdominal surgery also showed that physical fitness was an
With the physiological stress of any major operation, patients independent predictor of postoperative recovery in addition to
experience a drop in their functional status. In most cases, they will conventional predictors of age and co-morbidities.15 Prediction
recover back to baseline. (See figure 1) models for mortality, discharge destination and length of hospital
stay were once again all significantly improved by the physical
Surgery activity and fitness factors.
Activity
Status Patient
With the increasing evidence of the benefits of better preoperative
approaching
surgery… ry CRF, it follows that a reasonable intervention for improving surgical
ve
eco outcomes is to introduce exercise training preoperatively.
Independent R
ine (See figure 3)
out
R
Line of
dependency Surgery
Activity
Dependent Status tion
abili
Preh y
er
ov
Independent Rec
Figure 1:
ine
ut
Ro
Line of
Patients who experience complications tend to have a slower and dependency
possibly less complete recovery and some may fail to recover ry
cove
their preoperative status. In these cases, this may lead to a loss of Dependent
ated Re
plic
independence and a much reduced quality of life long term. Com
(See figure 2)
Figure 3:
Surgery
Activity Patients undertaking preoperative exercise may experience a
Status reduced risk of complications, a shorter stay in hospital and a more
er
y rapid recovery, through enhanced physical fitness. Importantly,
ov if complications occur, prehabilitated patients may still recover
Independent Rec
ine sufficiently to retain their independent functional status
ut
Ro
Line of
dependency In the area of cancer surgery, aerobic exercise programs
ry undertaken prior to surgery have mainly shown improved function
cove
Dependent
ated Re and physical capacity.16 However, patients often now require
plic
Com neo-adjuvant chemo and radiotherapy before major rectal cancer
surgery, which can reduce physical fitness, potentially increasing
Figure 2:
their complications. In a recent and important intervention study
it has been shown that structured exercise intervention post
However, there is emerging evidence that exercise perioperatively chemo and radiotherapy is both feasible and can restore fitness to
improves surgical outcomes and reduces in patient times in hospital. baseline levels again.17
Surgical patients increasingly have complex medical co-morbidities
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 46 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 12:
Perioperative Surgery
Key points
• Poor cardiorespiratory fitness (CRF) increases the risk of
complications of major surgery
• Conversely, improving CRF preoperatively has been
associated with reduced complications
• CRF assessment offers a better prognosis than age alone in
major surgery
• CRF is an independent predictor of mortality and length of
stay in hospital
Conclusions
Surgeons, anaesthetists, nurses and those giving advice in primary
care should consider pre surgical exercise interventions as a useful
adjunct to therapy.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 47 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 13:
Sedentary Behaviour
Figure 1: Risk of all-cause
Part 1: Sedentary Behaviour Daily Sitting Time mortality decreases
as one moves from red to green
Source: Adapted from data
In the 2019 UK Chief Medical Officers (CMO) guidelines on physical from Ekelund et al 2016 (19)
activity,1 adults are advised to aim to minimise the amount of time
spent being sedentary, and when physically possible should break
up long periods of inactivity with at least light physical activity.
It has been thought that this sedentary time is likely to be in This study also found that, in comparison with other risk factors for
addition to the risks associated with insufficient MVPA. An health, the increased mortality risk (58%) in those who sit for more
Australian study estimated the extent to which TV viewing time than 8 hours/day and are also the least active, is similar to that of
reduced life expectancy. The research compared people who smoking20 and obesity.21
watched no TV with those who spend a lifetime average of 6 hrs
viewing a day and found the latter group were predicted to live 4.8 One would expect similar results when comparing physical
years less. The authors concluded that ‘TV viewing time may be activity and daily sitting times and TV-viewing times with all-cause
associated with a loss of life that is comparable to other major risk mortality. However, studies have suggested a greater effect of TV-
factors such as physical inactivity and obesity’.15 viewing on all-cause mortality,19, 22 and although high level activity
reduces considerably the risks associated from TV-viewing, it fails
With the strong evidence of the link between sedentary time to entirely remove this increased risk. 19
and poor cardiometabolic health, this may be a more important
indicator of poor health than MVPA levels.16 Thus it may be more What can we do practically in the workplace and at home to
effective in the prevention of type 2 diabetes to target reducing change this behaviour?
sedentary time rather than solely focusing on promoting MVPA. One simple way is to introduce the concept of NEAT (Non Exercise
Activity Thermogenesis), a term that refers to daily physical
Until recently, it has also been unclear whether sufficient levels activities that are not perceived as exercise or training.
of activity can modify by weakening or removing the damaging (see box 1 on next page). By promoting more standing, less sitting
effect of prolonged sitting as described above. 17, 18 A large meta- and more moving we now know that these activities, however
analysis of data from more than 1 million individuals,19 has explored small, are better than sitting; these small activities accumulate and
the associations of sedentary behaviour and physical activity with count towards our daily energy expenditure as well as reduce the
all-cause mortality. (see figure 1). Results suggest that across sitting sedentary risk factors.
time categories, all-cause mortality was considerably reduced with
higher levels of physical activity and eliminated in those who were Summary
the most active (60-75 min or more per day of moderate activity).19 As Health and Social Care Professionals, we may be able to do
little to alter the social changes that have occurred over the past
This level of activity is beyond the basic level of the Chief Medical few decades. However, by understanding the health problems
Officers (CMO) physical guidelines of 30 minutes a day (for which have developed from this, we can do more by advising and
five days a week) or 150 minutes a week of moderate intensity. guiding patients to think about their lifestyle and to address their
For these individuals, there were smaller increases in mortality health risks. Changing patterns of behaviour is not easy, but if small
risk associated with sitting time seen compared with the least changes are made and this is spread over large populations, then
active group (about 5 mins/day), even though the risks were not the effect will be significant. Increasing any physical activity is
completely eliminated.19 essential to mitigate the associated risks for inactivity.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 48 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 13:
Sedentary Behaviour
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 49 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 13:
Sedentary Behaviour
Part 2: Sedentary Behaviour and Musculoskeletal Disorders Back pain
Introduction Low back pain is one of the biggest causes of absence from the
Sedentary behaviour refers to any waking activity characterized by an workplace,7 accounts for a high demand on healthcare provision,
energy expenditure 1.5 metabolic equivalents and a sitting or reclining is multifactorial, and common aetiologies of which are; sedentary
posture. In general, this means that any time a person is sitting or lying behaviour, being overweight and obese, and harmful lifestyle
down, they are engaging in sedentary behaviour. Common sedentary choices e.g. smoking, poor diet, poor social interaction8.
behaviours include TV viewing, video game playing, computer screen Current thinking is moving away from rest and toward active
time, seated employment, driving and reading.1 recovery and rehabilitation alongside encouraging lifestyle
improvements. Physical inactivity is associated with in a clear
Lack of physical activity is a common factor in many dose-dependent manner9 with:
chronic conditions2 and inactivity has been directly linked to • narrower intervertebral discs
musculoskeletal changes.3 Physical inactivity is highlighted as a • higher fat content of lumbar muscle and fascial tissues
threat to musculoskeletal health across the lifespan.4 • high intensity low back pain and disability
Musculoskeletal disorders (MSDs) related to sedentary lifestyles A systemic review assessed how behavioural interventions
and minimal physical activity are: compare to no intervention and guideline-based active
• non-specific low back pain treatment 10 Interventions regarding behavioural approaches to
• sciatica/lumbar radicular pain help people better manage persistent low back were seen to
• osteoporosis yield good improvements in pain, disability and quality of life.
• osteoarthritis Another systemic review and meta-analysis11 of multidisciplinary
• neck pain with and without radiculopathy biopsychosocial rehabilitation (MBR) of patients with chronic low
• patellofemoral joint pain back pain consolidate this holistic approach finding MBR to be
• hip pain more effective than usual care (moderate quality evidence) and
physical treatments (low quality evidence) in decreasing pain and
It has been suggested that the mechanism through which the disability in people with chronic low back pain.
sedentary behaviour negatively affects joint health is largely
related to deconditioning.5 Further studies have shown the Lower back pain with lumbar radicular pain/sciatica is common7
greater risk of sarcopenia associated with longer sitting time.6 and through systematic review and meta-analysis, the risk of
The following section gives examples of the impact of sedentary occurrence has shown to be reduced with physical activity12
behaviour on some aspects of musculoskeletal health: increased with long smoking history, a high serum C-reactive
Deconditioning
Muscle fatigability
Muscle strength
Maximum cardiac output (Q) a-v 02
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 50 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 13:
Sedentary Behaviour
protein level,13 and being overweight and/or obese with a dose There is good evidence for the benefits of graded loading to
dependent relationship.14 Reviewing this alongside the Chief pathological tendons which can be applied to other tendinous
Medical Officers recommendation of 150 minutes per week of muscle attachment, such as patellar tendinopathy.22 Coupled with
moderate intensity exercise,15 sedentary lifestyle behaviour can this, obesity as a risk factor, has been identified for several types of
be suggested as a causative factor for non-specific low back pain. tendinopathy including: rotator cuff, elbow extensor compartment
A systematic review16 highlights the benefits of exercise therapy (tennis elbow), patellar, quadriceps, Achilles and the plantar fascia.23
for non-specific low back pain with regards to function and pain.
This highlights the need for patient specific exercise to encourage
participation and a move toward a more active lifestyle. Knee
In conclusion, sedentary lifestyles are a major factor in non- Musculoskeletal shoulder pathology includes: frozen shoulder,
specific low back pain and back pain with accompanying radicular rotator cuff pathology, and glenohumeral and acromioclavicular
pain and can be treated in many ways with exercise and a holistic joint osteoarthritis. Pain is frequently caused through falls and
multidisciplinary approach being particularly effective. degenerative changes in both the rotator cuff and glenohumeral
joint, particularly in elderly patients. Whereas exercise has been seen
Contraindications to be a highly effective treatment method for these conditions,27-29
Any suspected or known recent fracture, tumour or infection identification of factors associated with sedentary lifestyles have
of the back.18 been made in regards to increased risk of shoulder pathology.30
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 51 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 14:
This Chapter provides insight to how we can support people They do not always emerge in a linear sequence, but the logic
to strengthen their motivation and capability to become more is this: step one is to engage with the patient and establish an
physically active. agreed focus for the conversation; then the central task is evoking
the patient’s own motivation to change, followed by planning if
the person is ready for this. These processes are highlighted in the
Enhancing Motivation to Change example below, alongside other key skills.
Health promotion forms part of many primary care consultations, While conducting a full motivational interview may require more
be it advice about exercise, weight loss, smoking or alcohol. These time than is available through standard consultations, adopting
consultations are often fraught with difficulty, as many patients are the guiding style even in brief interactions can have similar
resistant to being told what to do or ‘what is good for them’. beneficial results.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 52 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 14:
This example is based on a fictitious consultation between a HCP: You don’t want to be pushed into this (HCP doesn’t try to
51 year old male and his healthcare professional (HCP). He is win the argument or be clever – just uses a listening statement)
overweight, with borderline raised BP, who gets short of breath
when walking secondary to his poor cardiovascular fitness and Pt: Exactly, but it might be worth thinking about. Thanks for not
sedentary job. He travels to work on the bus and works on the lecturing me HCP (laughs)
third floor of an office.
HCP: HCP summarises how patient feels and keeps the door open
HCP: OK, so that’s your tablets sorted out, and now I wanted to for another time.
ask you whether it’s ok with you to spend just a couple of minutes
talking about something completely different….. Would that be
OK? (Asking permission will help a lot) Six weeks later the patient returns for another check on his
borderline blood pressure.
Patient: Yeah OK, what’s that then?
HCP: Well thanks for coming back again. I saw you six weeks
HCP: It’s about physical activity. Would you mind if we chatted ago, didn’t I?
about that if I promise not to nag at you about it?
Pt: Yes, you asked me to come back to check the blood pressure.
Pt: Yeah OK, as long as you keep to that promise (laughs). (The
focus is clear. Engagement is not strong, yet.) HCP: (HCP checks BP) Well it’s still on the high side, so we could
now ask the question what will help you to get it down and
HCP: So rather than me talk about it, could you? Could you tell avoid this becoming a cause for concern in the future?
me how you feel about getting more exercise?
Pt: Well I know I don’t want any of those tablets for blood
Pt: Hate the thought to be honest with you. pressure if possible Doc.
HCP: You’re not persuaded about this one (That’s a reflective HCP: Sure, that’s fine for now. Can I raise the subject of exercise
listening statement, not a question) again, if I promise not to lecture you?
Pt: Well I do know that it would help my health (change talk), but Pt: You told me that last time, but fair game, you didn’t lecture
the effort is really too much. me, so yes fine (laughs)
HCP: You get quite a lot done each day, and adding exercise HCP: I promise again!
doesn’t seem like it could fit (another reflective listening statement)
Pt: I believe you again, but what now?
Pt: Yeah you guessed right, I don’t just sit around all day and the
thought of going to the gym just doesn’t fit for me. HCP: My question would be this: are there some simple small
steps you can take to introduce a little more exercise into
HCP: Going to the gym isn’t for you, you are busy enough and yet your daily life?
you know it would be good for your health to get more exercise,
have I got you? (A summary that also includes the change talk) Pt: I’m glad you are not on about the gym.
Pt: Yeah you’ve got me for sure. (Engagement is now much better, HCP: Sure, that’s too drastic for you (reflective listening)
as a result of listening and then summarising).
Pt: I don’t do drastic, my life’s busy enough.
HCP: Can I ask you how do you see the benefits of just a slow and
steady increase in exercise? (A question that allows the HCP to HCP: Small things might be possible (reflective listening again –
start evoking change talk) a guess about what might work)
Pt: Me? Well if it was slow, and I didn’t have to go crazy like at a Pt: Yes, maybe but I’m not sure what you mean by small things?
gym, it might help me (change talk).
HCP: Presents a range of options, not a single idea, with the aim
HCP: It would help you to feel healthier (a listening statement again, to of encouraging the patient to select thus: So that’s a number
reflect the change talk and it’s also a guess about why it might help) of possibilities. You will be the best judge of what might work
for you. (Reinforcing autonomy is a critical aspect of skilful
Pt: Sort of, but at least I could fit it in, and I might succeed, and I consulting about behaviour change).
could feel good about that. (More change talk)
Pt: Well of all those things you mention, there’s only two that
HCP: Because you don’t want to take on some big task like the make sense to me: walking up the stairs rather than the lift and
gym. What suits you more is something smaller to start with. getting off the bus 2 stops before work and walking the last part
(Reflecting again, trying to understand how he really feels) (patient emits change talk).
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 53 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 14:
HCP: You want to experiment and see what works for you The following case study is an example of how motivational
(more reflection). interviewing and the inclusion of self-regulatory techniques
may help someone to initiate changes to become more
Pt: Yeah I am happy to try those two things (change talk). physically active:
HCP: (Summarises all the change talk that has emerged). So you
don’t want tablets, and you think you might be able to walk up Sarah
the stairs at work, and get off the bus two stops early, and walk In recent years, 50 year old Sarah has experienced more and
into work. more bouts of prolonged unhappiness. She has not been
diagnosed with clinical depression and her primary healthcare
Pt: Knowing me, I’ll give it a go. It might help me to feel better professional (HCP) has recommended she becomes physically
about myself (change talk). active. She has done little or no purposeful exercise since
her teenage years when she used to hate sport and physical
HCP: And would you mind coming to see me for a brief catch-up education at school, finding it threatening and embarrassing.
in six weeks? Sarah is on the borderline between overweight and obese with
a BMI of 29 and has been recently been diagnosed with mild
Pt: Sure......Etc etc hypertension. She has a family history of type 2 diabetes.
During this discussion, Sarah shares her belief that being more
active could be important for her and might help her feel more
Watch this dialogue on You Tube describing the behavioural positive about herself and life in general, but that she has not
change dialogue tried to become more active previously as she is not confident
that she would be able to do enough to make a difference.
Sarah would value the benefits of being more active if it helped
Increasing Capability to change her to lose some weight and get her blood pressure down.
Sarah has friends who go to exercise classes, but feels she is
Changing behaviour can be thought of as having an initial not confident to join a group at the moment, but she would like
motivational phase in which people develop their own reasons to think she could join a group of women with similar kinds of
for and intention to change, and a subsequent volitional phase, in issues at some point.
which a person’s motivation is put into action. The motivational
phase can be very well supported by motivational interviewing, Sarah does not feel very sporty or athletic and finds it difficult
but other evidence-based behaviour change techniques, primarily to see ways in which she can be more active. Sarah’s primary
relating to self-regulation, are useful in providing to support HCP asks Sarah if she does much walking at the moment, and
the volitional phase of behaviour change. They help to support if increasing her walking could be a way to get more exercise
someone’s capability to take the first steps towards change, and to that Sarah feels is possible for her. Sarah appears surprised and
sustain these over time 8,9 encouraged that walking could be enough. Sarah also suggests
she is interested in going to the gym, but is not confident of
• Self-monitoring - knowing one’s starting point, and getting walking in for the first time. Having endorsed the importance
feedback on the outcome of attempts to change and progress of physical activity for health, and helped Sarah to identify
over time, some of other benefits that she may value, Sarah’s primary
• Goal setting – more specific goals (e.g., a time and place when HCP suggests that she may benefit from talking more about
one will exercise) and goals related to actions rather than the options with an exercise professional at the local exercise
outcomes (e.g., exercising twice a week rather than losing a referral service, and Sarah agrees to go along.
certain amount of weight) are shown to be more effective,
• Social support – having practical (e.g., having an exercise
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 54 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 14:
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 55 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 15:
Assessment of levels of activity: Muscle strength and endurance through balance training activities,
It is important to record the patient’s physical activity level to both are also essential to maintain mobility and prevention of falls,
establish a baseline for tracking progress and for understanding which increases in importance as we grow older. Flexibility is too
their existing risk. There are various tools for quantifying a patient’s often overlooked, but is also important as it reduces the possibility
level of physical activity, one of the simplest and most effective of injury, stiffness and an inability to perform simple tasks like
being the Scot-PASQ bending to tie shoe laces or hair washing.
• ‘The Scot-PASQ’. 1 A brief assessment using just 3 questions. There are some simple basic principles that can be used in
Used as a motivational screening tool to help raise the issue of ‘prescribing exercise’, which when grasped by patients, will
physical activity and deliver advice promote more enjoyment and increase motivation, helping them to
o In the past week, on how many days have you been get over some of their beliefs/fears of pain or difficulty.
physically active for a total of 30 minutes or more?
Warm up and Cool down
o If four days or less, have you been physically active for at It is desirable that individuals include a warm up and cool down as
least two and a half hours (150 minutes) over the course part of their activity. This may be the same activity performed at a
of the past week? lower intensity. For example, walking at a slow pace for your warm
up and cool down, with a moderate intensity walk for 30 minutes
o Are you interested in being more physically active? as the main activity.
Read the brief guidance on how to use the tool by Apply the FITT principle
downloading it here:
http://www.healthscotland.com/documents/6255.aspx • Frequency How many times a week for an activity?
Many of the health benefits of physical activity come from The most important aspect to establish first is frequency, as
improved cardiovascular fitness using aerobic exercise. without a daily routine pattern it will not become a lifestyle change.
However, muscle, bone strength and resistance exercises are Motivation, or the desire to change, is what gets you started, but
often overlooked but play a critical role in ensuring we build our habit is what keeps you going.
strength for good muscular and skeletal health, and in maintaining
physical function. When undertaking muscle strengthening Those who have been inactive for a long time may need to start at
activities, it is important to work all the major muscle groups. a low Intensity. If walking, they will need to increase gradually over
Bone strengthening involves moderate and high impact activities time to a moderate intensity.
to stimulate bone growth and repair.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 56 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 15:
Moderate exercise when walking is when someone is breathing a How many steps is enough?
little faster and feeling a little warmer than normal but still able to Differing advice is often given over how many steps is good for
hold a conversation, taking a few extra breaths between sentences. our health, with 10,000 steps a day as the commonest quoted. 5-7
If they are gasping between words, then they are engaging in high Yet, adult physical activity guidelines advise at least 30 minutes
intensity activity. This is important to recognise in recommending of moderate intensity activity per day and this translates to only
activity. For example, walking up an incline may be mild to 3000 - 4000 steps, 8, 9
moderate exercise for a teenager, but would be vigorous exercise
to someone who is inactive, vulnerable or elderly. If walking, aim to To fit with public health guidelines these should be: 10, 11
increase the number of minutes of the walk first, before increasing
the intensity (by walking faster or uphill). • Of moderate intensity (i.e. over 100 steps/minute) 8
Time, or how long to exercise, should be established excluding any • Accumulated in at least 10 minute bouts
warm up or cool down. Guidelines previously advised that bouts
of physical activity of 10 min or more accumulated throughout the • Taken over and above some minimal level of physical
day are as effective as longer sessions. However, we now know activity (i.e., number of daily steps) below which individuals
that even smaller increases in physical activity can contribute may be classified as sedentary
to improved health and quality of life and people should be
encouraged to move more as often as they can. An accelerometer or pedometer will however, also register the
low intensity steps taken with everyday movements. These are
There are many activities available that can be started and it part of the daily step count but it is unlikely they will contribute
is important to find a Type of exercise that the individual finds as much to the overall health benefits. It is therefore suggested
enjoyable convenient, affordable and achievable. Walking, cycling that, total steps of less than 5000 steps/day, may reflect a level
and swimming are three of the commonest and available to of sedentary activity which is associated with a higher prevalence
virtually everyone, but there are many more. Dancing, yoga, Pilates of obesity. 10, 12 However, adding 3000-4000/day moderate
and Tai Chi are also very popular and all of these may help to intensity steps to this, then equates with a hierarchy level of
prevent falls and promote core strength. 7500-9999 steps/day (somewhat active) which may be more
useful for monitoring or motivation purposes.10
Definitions of moderate and vigorous intensity
Moderate intensity physical activity causes adults to feel warmer,
breathe harder and the heart beats faster with the example of
gh
Physically
nd
maintain a conversation
E
ily
Da
Physically
Some people find it helpful to monitor their progress and use this
w
Inactive
Lo
• Pedometers – cheap and easy to use, but not always reliable 4 In summary, every step may be counted with even small
increases in physical activity contributing to improved health and
• Smart phones and ‘Fitbits’ – now commonly available and quality of life
with monitoring apps
Getting Started
• Accelerometers – more reliable and can be linked to a Increasing physical activity for many is difficult and
computer program for monitoring encouragement and ideas are needed to help integrate activity
into daily life.
• Walk4life – the walking web based site which is free to join; There are many ways of increasing activity and walking is one
it uses ordinance survey maps and routes and has a ‘track of the easiest ways. If 30 minutes all at once seems too much,
your progress’ page to monitor your own fitness then try short bouts in the day, such as 5-10 minutes and try to
build that up over time. We now know that even relatively small
increases in physical activity can contribute to improved health
and quality of life.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 57 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 15:
For example: • Swimming – traditional fun for the family and water aerobics
• Leave the car at home for short trips to shops or friends for some. Try to swim a little longer each time and try not to
take too many rests
• Walk to school with the children when you can
• Sport – There are a huge variety of local sports
• Park the car when used, at the far side of a car park opportunities available all of which can confer physical and
mental health benefits for people of all ages and abilities.
• If commuting, get off the train or bus one or two stops For information on local clubs and opportunities see
early to fit in a walk to work http://www.sports-clubs.net/
• Avoid lifts and escalators –use the stairs • Walking football is becoming popular, a new activity for
older people or those who cannot run any more
• Use a standing desk to work from
• Martial arts are popular and improve strength and flexibility
• Get up from a desk to walk across the office to speak to a as well as cardiac fitness
colleague rather than phone or email
• Yoga and Pilates – excellent activities for flexibility,
• Promote and support standing meetings (Standing burns 15 core strength and posture to relieve and prevent many
calories an hour compared to 5 an hour sitting) back problems.
• Brushing the yard or raking up leaves • Structural issues including cost, organisation of local
services, transport and provision of childcare
• Washing and polishing the car by hand
• Environmental issues such as lighting, safety,
• DIY – carpentry, sanding, painting, building etc state of paths, cycleways etc
There are many other activities but most important is finding a • Social factors including family support and social
form of exercise that the individual finds enjoyable, social and interactions
achievable.
These factors will vary from individual to individual and the best
• Walking – walk with a friend or join a walking group. way to identify both specific issues and potential facilitators
http://www.walk4life.info has information on local walks and is through motivational interviewing, goal setting, progress
walking groups for many areas. There are also health walks, monitoring and planning for relapse.
which are short led walks in most local areas
• Cycling – many cycle paths have or are being developed Brief Interventions
across the UK and it is a fun activity for all the family.
http://www.sustrans.org.uk/ncn/map/national-cycle-network There is good evidence of the value and effectiveness of brief
interventions by health professionals in supporting a range of
• Cycle or walk around your local park – getting outside behaviour changes including improving physical activity levels.
and being in green space can help you feel better, there are (NICE, 2014) 13. Even a ‘very brief intervention’ (30 secs to 2
also lots of things to see as well, like wildlife, other people minutes) can prove beneficial if the patient is directed for further
and flowers advice or assistance, which might be anything from information
on local services and opportunities to formal referrals.
• Dance – increasingly popular, enjoyable and social for people
of all ages, genders and abilities
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 58 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 15:
As patients present with more complex problems, with one Apart from the absolute contraindications above, there are also
or more co-morbidities, doctors or nurses may prefer to refer a series of relative precautions or contraindications within certain
to Local Exercise Schemes or physiotherapists depending on medical conditions. These largely occur when a few conditions
the conditions and level of risk, for more detailed advice on become unstable and then exercise may become contraindicated
specific exercise plans. However, there is still plenty of simple for a period of time. Conditions which are well controlled will allow
encouragement regarding walking, gardening and housework, the vast majority to remain active.
which can be done in parallel, as any activity provides a valid
health benefit. Whilst pregnancy is a natural process, there are some
complications of pregnancy where women will be advised against
A small number of patients require rehabilitation through exercise and healthcare students should be aware of these.
specialised physiotherapists or high level 4 gym instructors, or In reality, it is nearly always safe to encourage and motivate people
through pulmonary or cardiac rehabilitation units. Assessments to increase their activity through a brief intervention. However,
of these patients may need to be made by Cardiac, Respiratory when referring to an exercise referral scheme, the health care
or, if available, Sport and Exercise Medicine (SEM) consultants. practitioner should ensure the person is stable with none of the
contraindications below.16
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 59 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
CHAPTER 15:
Osteoporosis Contraindications 22
• Avoid high impact activities or those with a Disclaimer
high risk of falling
Health professionals are not trained in giving exercise programmes
Asthma Contraindications 21 and this resource is not intended to encourage anyone to go
• Unstable asthma or actively wheezing. beyond their own experience. However, guiding someone to walk,
• In case of acute exacerbation or infection, a swim, cycle or dance is within everyone’s understanding.
break in exercise training is recommended
COPD Contraindications 23
• Pulmonary rehabilitation is not suitable for
people who are unable to walk, who have
unstable angina or who have had a recent
myocardial infarction.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 60 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
Acknowledgements
We are grateful to all of the people who have contributed to
this 2020 edition of this guidebook.
Editorial team:
Mr Andrew Tullo, Elizabeth Johnson and Malcolm Ward.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 61 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
Introduction 13. Nieman DC. Exercise, infection, and immunity. Int. J. Sports
1 The UK Chief Medical Officers physical activity guidelines Med. 1994; 15 Suppl 3, S131-41
report. (cited 2020 Sept 1)
https://www.gov.uk/government/publications/physical- 14. Nieman DC. Infectious episodes in runners before and after
activity-guidelines-uk-chief-medical-officers-report the Los Angeles Marathon. J. Sports Med. Phys. Fitness 1990;
30, 316–28
2. 2018 Physical Activity Guidelines Advisory Committee. 2018.
Physical Activity Guidelines Advisory Committee Scientific 15. Fahlma MM. Mucosal IgA and URTI in American college
Report. Washington, DC: U.S. Department of Health and football players: a year longitudinal study. Med. Sci. Sports
Human Services; 2018. Exerc. 2005; 37, 374–80
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 62 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
29. Suzuki K. Endurance exercise causes interaction among 45. Coates G. Hindlimb and lung lymph flows during prolonged
stress hormones, cytokines, neutrophil dynamics, and muscle exercise. J. Appl. Physiol. 1993; 75, 633–8
damage. J. Appl. Physiol. 1999; 87, 1360–7
46. Havas E. Albumin clearance from human skeletal muscle during
30. Nieman DC. Quercetin’s influence on exercise-induced changes prolonged steady-state running. Exp. Physiol. 2000; 85, 863–8
in plasma cytokines and muscle and leukocyte cytokine
mRNA. J. Appl. Physiol. 2007; 103, 1728–35 47. Won, GCL. Hallmarks of improved immunological responses
in the vaccination of more physically active elderly females.
31. Suzuki K. Effects of exhaustive endurance exercise and its one- Exerc. Immunol. Rev. 2019; 25, 20–33.
week daily repetition on neutrophil count and functional status
in untrained men. Int. J. Sports Med. 1996; 17, 205–12 48. Simpson R.J. Exercise and the Regulation of Immune
Functions. Prog. Mol. Biol. Transl. Sci. 2015; 135, 355–80
32. Nieman DC. The compelling link between physical activity and
the body’s defense system. J. Sport Heal. Sci. 2019; 8, 201–217
Chapter 2: Physical Activity Guidelines
33. Walsh NP. Recommendations to maintain immune health in 1. The WHO Global Action Plan on Physical Activity 2018-30
athletes. Eur. J. Sport Sci. 2018; 18, 820–831 (cited 2020 Nov17) Available from https://apps.who.int/iris/
bitstream/handle/10665/272722/9789241514187-eng.pdf?ua=1
34. Schwellnus M. How much is too much ? ( Part 2 ) International
Olympic Committee consensus statement on load in sport and 2. WHO guidelines on physical activity and sedentary behaviour
risk of illness. Br. J. Sports Med. 2016; 50, 1043–1052 (cited 2020 Nov 26) Available from:
https://www.who.int/publications/i/item/9789240015128
35. Tison G. Worldwide Effect of COVID-19 on Physical Activity:
A Descriptive Study. Ann. Intern. Med. 2020; M20-2665 Chapter 2: The 2019 UK Physical Activity Guidelines
1. The UK Chief Medical Officers physical activity guidelines
36. Deschasaux-Tanguy M. Diet and physical activity during the report. (cited 2019 Sept 9)
COVID-19 lockdown period (March-May 2020): results from https://www.gov.uk/government/publications/physical-
the French NutriNet-Sante cohort study. medRxiv 2020.06.04; activity-guidelines-uk-chief-medical-officers-report
20121855
2. Department of Health, Physical Activity, Health Improvement
37. Kipps C. Enforced inactivity in the elderly and diabetes risk: and Protection. Start Active, Stay Active: A report on physical
initial estimates of the burden of an unintended consequence activity from the four home countries’ Chief Medical Officers.
of COVID-19 lockdown. medRxiv 2020.06.06; 20124065 doi:10. London: Department of Health; 2011
1101/2020.06.06.20124065.
3. Carson V, et al. Systematic review of the relationships between
38. Dietz W. Obesity and its Implications for COVID-19 Mortality. physical activity and health indicators in the early years (0-4
Obesity (Silver Spring). 2020; 28, 1005 years). BMC Public Health. 2017;17
39. Sattar N. Obesity a Risk Factor for Severe COVID-19 Infection: 4. WHO. Guidelines on physical activity, sedentary behaviour and
Multiple Potential Mechanisms. Circulation (2020) doi:10.1161/ sleep for children under 5 years of age. Geneva: World Health
CIRCULATIONAHA.120.047659. Organisation; 2019
40. Duggal NA. Can physical activity ameliorate 5. WHO. Commission on Ending Childhood Obesity (ECHO).
immunosenescence and thereby reduce age-related multi- Geneva: World Health Organisation; 2016.
morbidity? Nat. Rev. Immunol. 2019; 19, 563–572
6. WHO. Report of the Commission on Ending Childhood
41. Martin SA. Exercise and respiratory tract viral infections. Obesity. Implementation Plan: Executive Summary. Geneva:
Exerc. Sport Sci. Rev. 2009; 37, 157–64 World Health Organisation; 2017 (WHO/NMH/PND/ECHO/17.1).
42. Wallace DL. Prolonged exposure of naïve CD8+ T cells to 7. Hallal PC, et al. Global physical activity levels: surveillance
interleukin-7 or interleukin-15 stimulates proliferation without progress, pitfalls, and prospects. Lancet. 2012;380(9838):247-57.
differentiation or loss of telomere length. Immunology 2006;
119, 243–53 8. Aubert S, et al. Global Matrix 3.0 Physical Activity Report Card
Grades for Children and Youth: Results and Analysis From 49
43. Haugen F. IL-7 is expressed and secreted by human skeletal Countries. J Phys Act Health. 2018;15(S2):S251-S73.
muscle cells. Am. J. Physiol. Cell Physiol. 2010; 298, C807-16
9. Poitras VJ, et al. Systematic review of the relationships between
44. Green DJ. Vascular Adaptation to Exercise in Humans: objectively measured physical activity and health indicators
Role of Hemodynamic Stimuli. Physiol. Rev. 2017; 97, 495–528 in school-aged children and youth. Appl Physiol Nutr Me.
2016;41(6):S197-S239.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 63 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
10. Carson V, et al. Systematic review of sedentary behaviour and 22. Physical Activity Policy and Health Improvement Directorate.
health indicators in school-aged children and youth: an update. (2009) The general practice physical activity questionnaire
Appl Physiol Nutr Me. 2016;41(6):S240-S65. (GPPAQ); a screening tool to assess adult physical activity
levels within primary care. (cited 2020 Aug 30) Available at:
11. Chaput JP, et al. Systematic review of the relationships http://webarchive.nationalarchives.gov.uk/20130107105354/
between sleep duration and health indicators in school-aged http://www.dh.gov.uk/prod_consum_dh/groups/dh_
children and youth. Appl Physiol Nutr Me. 2016;41(6):S266-S82. digitalassets/@dh/@en/@ps/documents/digitalasset/
dh_112134.pdf
12. Cooper AR, et al. Objectively measured physical activity
and sedentary time in youth: the International children’s 23. The Scot-PASQ. (Cited 2020 Aug 30)
accelerometry database (ICAD). Int J Behav Nutr Phys Act. http://www.healthscotland.com/uploads/documents/20388-
2015;12:113. Epub 2015/09/18. ScreeningTools.pdf
21. Royal National Osteoporosis Society. Strong, Steady and 9. Buffart LM, Sweegers MG, May AM, et al. Targeting exercise
Straight: an expert consensus statement on physical activity interventions to patients with cancer in need; an individual
and exercise for osteoporosis. Royal National Osteoporosis patient data meta-analysis. Journal of National Cancer Institute.
Society, Bath. Dec 2018 2018;110(11):1190-1200
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 64 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
10. Chan DN, Lui LY, So WK. Effectiveness of exercise programmes 23. Je Y, Jeon JY, Giovannucci EL, Meyerhardt JA. Association
on shoulder mobility and lymphoedema after axillary lymph between physical activity and mortality in colorectal cancer:
node dissection for breast cancer: systematic review. Journal a meta-analysis of prospective cohort studies. International
of Advanced Nursing. 2010 Sep 1;66(9):1902-14. Journal of Cancer. 2013 Oct 15;133(8):1905-13.
11. McNeely ML, Campbell K, Ospina M, et al. Exercise interventions 24. Schmid D, Leitzmann MF. Association between physical
for upper-limb dysfunction due to breast cancer treatment. activity and mortality among breast cancer and colorectal
Cochrane Database of Systematic Reviews 2010, Issue 6. Art. cancer survivors: a systematic review and meta-analysis.
No.: CD005211. DOI: 10.1002/14651858.CD005211.pub2. Annals of Oncology. 2014 Jul 1;25(7):1293-311.
12. Fong DY, Ho JW, Hui BP, et al. Physical activity for cancer 25. Betof AS, Dewhirst MW, Jones LW. Effects and potential
survivors: meta-analysis of randomised controlled trials. mechanisms of exercise training on cancer progression: a
BMJ. 2012 Jan 31;344:e70. translational perspective. Brain, Behaviour, and Immunity. 2013
Mar 15;30:S75-87.
13. World Cancer Research Fund, American Institute for Cancer
Research . Colorectal Cancer: Food, nutrition, physical activity, 26. Richman EL, Kenfield SA, Stampfer MJ, et al. Physical activity
and the prevention of colorectal cancer. 2017. (cited 2019 Oct after diagnosis and risk of prostate cancer progression: data
15) Available from: from the cancer of the prostate strategic urologic research
http://www.wcrf.org/int/research-we-fund/continuous- endeavour. Cancer Research. 2011 Jun 1;71(11):3889-95.
update-project-findings-reports/colorectal-cancer
27. Kenfield SA, Stampfer MJ, Giovannucci E, Chan JM. Physical
14. Doyle C, Kushi LH, Byers T, et al. Nutrition and physical activity activity and survival after prostate cancer diagnosis in the
during and after cancer treatment: an American Cancer health professionals follow-up study. Journal of Clinical
Society guide for informed choices. CA: A Cancer Journal for Oncology. 2011 Jan 4;29(6):726-32.
Clinicians. 2006 Nov 1;56(6):323-53.
28. Jones LW, Hornsby WE, Goetzinger A, et al. Prognostic
15. Thorsen L, Skovlund E, Strømme SB, et al. Effectiveness of significance of functional capacity and exercise behaviour
physical activity on cardiorespiratory fitness and health-related in patients with metastatic non-small cell lung cancer.
quality of life in young and middle-aged cancer patients shortly Lung Cancer. 2012 May 31;76(2):248-52.
after chemotherapy. Journal of Clinical Oncology. 2005 Apr
1;23(10):2378-88. 29. Ruden E, Reardon DA, Coan AD, et al. Exercise behaviour,
functional capacity, and survival in adults with malignant
16. Thune I, Smeland S. Can physical activity prevent cancer? recurrent glioma. Journal of Clinical Oncology. 2011 Jun
Tidsskr Nor Laegeforen. 2000 Nov 10;120(27):3296-301 20;29(21):2918-23.
(article in Norwegian)
30. National Institute for Health and Care Excellence, London.2018
17. Courneya KS, Mackey JR, Bell GJ, et al. Randomized controlled Early and locally advanced breast cancer. NICE guideline 101
trial of exercise training in postmenopausal breast cancer (cited 2020 Aug 15). Available from:
survivors: cardiopulmonary and quality of life outcomes. https://www.nice.org.uk/guidance/ng101
Journal of Clinical Oncology. 2003 May 1;21(9):1660-8.
31. National Institute for Health and Care Excellence. London. 2017.
18. Oldervoll LM, Loge JH, Lydersen S, et al. Physical exercise Advanced breast cancer: diagnosis and treatment.
for cancer patients with advanced disease: a randomized NICE Clinical guideline 81 (cited 2020 Aug 15). Available from:
controlled trial. The Oncologist. 2011 Nov 1;16(11):1649-57. https://www.nice.org.uk/guidance/cg81
19. Albrecht TA, Taylor AG. Physical activity in patients with 32. Macmillan Cancer Support. Physical activity evidence review.
advanced-stage cancer: a systematic review of the literature. (cited 2020 Aug 15) Available from:
Clinical Journal of Oncology Nursing. 2012 Jun 1;16(3):293. https://www.macmillan.org.uk/_images/the-importance-
physical-activity-for-people-living-with-and-beyond-cancer_
20. Heywood R, McCarthy AL, Skinner TL. Safety and feasibility tcm9-290123.pdf
of exercise interventions in patients with advanced cancer: a
systematic review. Supportive Care in Cancer. 2017 Jul 25:1-20. 33. Thune I. Cancer Ch 19. Swedish National Institute of Public
Health. Physical Activity in the prevention and treatment of
21. Dittus KL, Gramling RE, Ades PA. Exercise interventions disease. 2010. (cited 2020 Aug 15). Available from:
for individuals with advanced cancer: a systematic review. http://www.fyss.se/wp-content/uploads/2018/01/19.-Cancer.
Preventive Medicine. 2017 Nov; 104:124-132 pdf
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 65 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
8. Anderson L, Oldridge N, Thompson DR, et al. Exercise-based 4. Lewinter C, Doherty P, Gale CP, et al. Exercise-based cardiac
cardiac rehabilitation for coronary heart disease: Cochrane rehabilitation in patients with heart failure: a meta-analysis of
systematic review and meta-analysis. Journal of the American randomised controlled trials between 1999 and 2013. European
College of Cardiology. 2016 Jan 12;67(1):1-2. Journal of Preventive Cardiology. 2015 Dec;22(12):1504-12.
9. National Audit of Cardiac Rehabilitation (NACR). The 2019 5. Heart Failure Society of America. Executive summary: HFSA
Annual Report. (cited 2020 Aug 14) Available from: 2010 comprehensive heart failure practice guideline. Journal of
https://www.bhf.org.uk/informationsupport/publications/ Cardiac Failure. 2010 Jun 30;16(6):475-539.
statistics/national-audit-of-cardiac-rehabilitation-quality-and-
outcomes-report-2019 6. National Institute for Health and Care Excellence. London.
Chronic heart failure in adults: diagnosis and management.
10. National Institute for Health and Care Excellence. London. 2013. 2018. NICE guideline 106 (cited 2020 Aug 14). Available from:
Myocardial infarction: cardiac rehabilitation and prevention of https://www.nice.org.uk/guidance/ng106
further cardiovascular disease. NICE clinical guideline 172
(cited 2020 Aug 14). Available from: 7. BACR 2006 Phase IV Exercise Instructor Training Manual and
https://www.nice.org.uk/guidance/cg172 ACSM (2009) Guidelines for Exercise Testing and Prescription.
(cited 2020 Aug 14) Available from:
11. BACR 2006 Phase IV Exercise Instructor Training Manual and http://www.bacpr.com/resources/BACPR_Protocol.pdf
ACSM (2009) Guidelines for Exercise Testing and Prescription.
(cited 2020 Aug 14) Available from:
http://www.bacpr.com/resources/BACPR_Protocol.pdf
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 66 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
Atrial fibrillation (AF) 7. Somers VK, White DP, Amin R, et al. Sleep apnea and
1. Gorenek B, Pelliccia A, Benjamin EJ et al. European Heart cardiovascular disease. Circulation 2008;(10)118:1080–1111.
Rhythm Association (EHRA)/European Association of
Cardiovascular Prevention and Rehabilitation (EACPR) position Hypertension
paper on how to prevent atrial fibrillation endorsed by the 1. Whelton SP, Chin A, Xin X, He J. Effect of aerobic exercise on
Heart Rhythm Society (HRS) and Asia Pacific Heart Rhythm blood pressure: A meta-analysis of randomized controlled
Society (APHRS). European Journal of Preventive Cardiology. trials. Annals of Internal Medicine. 2002; 136 (7): 493-503
2017;24(1):4-40
2. Liu X, Zhang D, Liu Y, et al. Dose-response association between
2. Woodcock J, Franco OH, Orsini N, Roberts I. Non-vigorous physical activity and incident hypertension: a systematic review
physical activity and all-cause mortality: systematic review and meta-analysis of cohort studies. Hypertension (Dallas).
and meta-analysis of cohort studies. International Journal of 2017;69(5):813-20.
Epidemiology. 2010 Jul 14;40(1):121-38 3. Diaz KM, Shimbo D. Physical activity and the prevention of
3. Menezes AR, Lavie CJ, DiNicolantonio JJ, et al. Atrial fibrillation hypertension. Current hypertension reports.
in the 21st century: a current understanding of risk factors and 2013 Dec 1;15(6):659-68.
primary prevention strategies. Mayo Clin Proc 2013;88:394–409
4. Pescatello LS, Franklin BA, Fagard R, et al. Exercise and
4. Kwok CS, Anderson SG, Myint PK, et al. Physical activity and hypertension. Medicine and Science in Sports and Exercise.
incidence of atrial fibrillation: a systematic review and meta- 2004 Mar 1;36(3):533-53.
analysis. Int J Cardiol. 2014;177:467–76.
5. Cornelissen VA, Smart NA. Exercise training for blood pressure:
5. Parry-Williams G, Sharma S. The effects of endurance exercise a systematic review and meta-analysis. Journal of the American
on the heart: panacea or poison? Nat Rev Cardiol. 2020 Heart Association. 2013 Feb 22;2(1):e004473.
https://doi.org/10.1038/s41569-020-0354-3
6. American College of Sports Medicine. Physical activity,
6. Mohanty S, Mohanty P, Tamaki M et al. Differential association physical fitness, and hypertension. Medicine Science in Sports
of exercise intensity with risk of atrial fibrillation in men and Exercise. 1993;25:i-x.
and women: evidence from a meta-analysis. J. Cardiovasc.
Electrophysiol. 2016;27(9):1021-9 7. Prospective Studies Collaboration. Age-specific relevance of
usual blood pressure to vascular mortality: a meta-analysis of
Obstructive sleep apnoea syndrome (OSAS) individual data for one million adults in 61 prospective studies.
1. Piepoli MF, Hoes AW, Agewall S, et al. 2016 European The Lancet. 2002 Dec 14;360(9349):1903-13.
Guidelines on cardiovascular disease prevention in clinical
practice: The Sixth Joint Task Force of the European Society 8. National Institute for Health and Care Excellence. London.
of Cardiology and Other Societies on Cardiovascular Disease Hypertension in adults: diagnosis and management. 2019
Prevention in Clinical Practice (constituted by representatives NICE guideline 136. (cited 2020 Aug 14) Available at:
of 10 societies and by invited experts) Developed with https://www.nice.org.uk/guidance/ng136
the special contribution of the European Association for
Cardiovascular Prevention & Rehabilitation (EACPR). 9. BACR 2006 Phase IV Exercise Instructor Training Manual and
Eur Heart J. 2016 Aug 1;37(29):2315-81. ACSM (2009) Guidelines for Exercise Testing and Prescription.
(cited 2020 Aug 14) Available from:
2. Greenberg DL. Obstructive sleep apnea. In Kryger MH, Roth T, http://www.bacpr.com/resources/BACPR_Protocol.pdf
Dement WC. Principles and practice of sleep medicine, 5th ed.
St. Louis: Elsevier Saunders; 2017 10. Musini VM, Tejani AM, Bassett K, Wright JM. Pharmacotherapy
for hypertension in the elderly. Cochrane Database of
3. Kato M, Adachi T, Koshino Y, et al. Obstructive sleep apnea and Systematic Reviews 2009, Issue 4. Art. No.: CD000028. DOI:
cardiovascular disease. Circ J. 2009;73(8):1363-1370 10.1002/14651858.CD000028.pub2.
4. Redline S, Yenokyan G, Gottlieb DJ, et al. Obstructive sleep 11. Brooks JH, Ferro A. The physician’s role in prescribing
apnea hypopnea and incident stroke: the Sleep Heart Health physical activity for the prevention and treatment of essential
Study. Am J Respir Crit Care Med. 2010;182(2):269-277. hypertension. JRSM Cardiovascular Disease. 2012 Jul;1(4):1-9.
5. United States Office of Disease Prevention and Health 12. Nocon M, Hiemann T, Müller-Riemenschneider F, et
Promotion. Second Edition of Physical Activity Guidelines for al Association of physical activity with all-cause and
Americans. 2018. (cited 2020 Aug 30) Available from: cardiovascular mortality: a systematic review and meta-
https://health.gov/paguidelines/second-edition/ analysis. European Journal of Cardiovascular Prevention and
Rehabilitation. 2008 Jun;15(3):239-46.
6. Gonzaga C, Bertolami A, Bertolami M, Amodeo C, Calhoun
D. Obstructive sleep apnea, hypertension and cardiovascular
diseases. J Hum Hypertens 2015;29: 705–712.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 67 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
13. Naci H, Salcher-Konrad M, Dias S, et al. How does exercise 3. United States Office of Disease Prevention and Health
treatment compare with antihypertensive medications? Promotion. Second Edition of Physical Activity Guidelines for
A network meta-analysis of 391 randomised controlled trials Americans. 2018. (cited 2020 Aug 30) Available from:
assessing exercise and medication effects on systolic blood https://health.gov/paguidelines/second-edition/
pressure. British Journal of Sports Medicine 2019;53:859-869.
4. Grimby G, Willén C, Engardt M, Summerhagen KS. Ch 47.
Lipids Stroke. Swedish National Institute of Public Health. Physical
1. Durstine JL, Grandjean PW, Davis PG, et al. Blood lipid and Activity in the prevention and treatment of disease. 2010.
lipoprotein adaptations to exercise. Sports Medicine. (cited 2020 Aug 20) Available from:
2001 Dec 1;31(15):1033-62. http://www.fyss.se/wp-content/uploads/2018/01/47.-Stroke.pdf
2. Shaw KA, Gennat HC, O’Rourke P, Del Mar C. Exercise for 5. Naci H, Ioannidis JP. Comparative effectiveness of
overweight or obesity. Cochrane Database of Systematic exercise and drug interventions on mortality outcomes:
Reviews 2006, Issue 4. Art. No.: CD003817. DOI: metaepidemiological study. BMJ. 2013 Oct 1;347:f5577.
10.1002/14651858.CD003817.pub3.
3. Kodama S, Tanaka S, Saito K, et al. Effect of aerobic exercise 6. Saunders DH, Sanderson M, Hayes S,et al. Physical fitness
training on serum levels of high-density lipoprotein cholesterol: training for stroke patients. Cochrane Database of Systematic
a meta-analysis. Archives of Internal Medicine. 2007 May Reviews. 2016 Mar24:3:CD003316. Doi: 10.1002/14651858.
28;167(10):999-1008. CD003316pub6
4. Björck L, Thelle DS. Ch 33. Lipids. Swedish National Institute of 7. Potempa K, Lopez M, Braun LT, et al. Physiological outcomes
Public Health. Physical Activity in the prevention and treatment of aerobic exercise training in hemiparetic stroke patients.
of disease. 2010. (cited 2020 Aug 20). Available at Stroke. 1995 Jan 1;26(1):101-5.
http://www.fyss.se/wp-content/uploads/2018/01/33.-Lipids.pdf
8. National Institute for Health and Care Excellence. London.
Peripheral Arterial Disease Stroke rehabilitation in adults: 2013 NICE clinical guideline 162.
1. Morley RL, Sharma A, Horsch AD and Hinchcliffe R. Peripheral (cited 2020 Aug 20) Available from:
artery disease. BMJ 2018;360:j5842 https://www.nice.org.uk/guidance/cg162
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 68 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
7. Zelle DM, Klaassen G, van Adrichem E, et al. Physical inactivity: 20. Watson EL, Greening NJ, Viana JL, et al. Progressive resistance
A risk factor and target for intervention in renal care. Nature exercise training in CKD: a feasibility study. American Journal of
Reviews Nephrology. 2017 Mar 1;13(3):152-68. Kidney Diseases. 2015 Aug 31;66(2):249-57.
8. Robinson-Cohen C, Littman AJ, Duncan GE, et al. Physical 21. Greenwood SA, Koufaki P, Mercer TH, et al. Effect of
activity and change in estimated GFR among persons with exercise training on estimated GFR, vascular health, and
CKD. Journal of the American Society of Nephrology. 2014 cardiorespiratory fitness in patients with CKD: a pilot
Feb;25(2):399-406. randomized controlled trial. American Journal of Kidney
Diseases. 2015 Mar 31;65(3):425-34.
9. Chen IR, Wang SM, Liang CC, et al. Association of walking with
survival and RRT among patients with CKD stages 3–5. Clinical 22. Takahash A, Hu SL, Bostom A. Physical Activity in Kidney
Journal of the American Society of Nephrology. Transplant Recipients: A Review. American Journal of Kidney
2014 Jul;9(7):1183-9. Diseases. 2018 S0272-6386(18)30069-6
10. Heiwe S, Jacobson SH. Exercise training for adults with chronic 23. Thangarasa T, Imtiaz R, Hiremath S, Zimmerman D. Physical
kidney disease. Cochrane Database of Systematic Reviews Activity in Patients Treated With Peritoneal Dialysis: A
2011, Issue 10. Art. No.: CD003236. DOI: 10.1002/14651858. Systematic Review and Meta-analysis. Canadian Journal of
CD003236.pub2. Kidney Health and Disease 2018 5; 2054358118779821.
11. Howden EJ, Fassett RG, Isbel NM, Coombes JS. Exercise 24. Young HM, March DS, Graham-Brown MP, et al. Effects of
training in chronic kidney disease patients. Sports Medicine. intradialytic cycling exercise on exercise capacity, quality of
2012 Jun 1;42(6):473-88. life, physical function and cardiovascular measures in adult
haemodialysis patients: a systematic review and meta-analysis.
12. Heiwe S, Jacobson SH. Exercise training in adults with CKD: Nephrology Dialysis Transplantation. 2018 Mar 28.
a systematic review and meta-analysis. American Journal of
Kidney Diseases. 2014 Sep 30;64(3):383-93. 25. Gould DW, Graham-Brown MP, Watson EL, et al. Physiological
benefits of exercise in pre-dialysis chronic kidney disease.
13. Cheema BS, Chan D, Fahey P, Atlantis E. Effect of progressive Nephrology. 2014 Sep 1;19(9):519-27.
resistance training on measures of skeletal muscle hypertrophy,
muscular strength and health-related quality of life in patients 26. Smart NA, Williams AD, Levinger I, et al. Exercise & Sports
with chronic kidney disease: a systematic review and meta- Science Australia (ESSA) position statement on exercise and
analysis. Sports Medicine. 2014 Aug 1;44(8):1125-38. chronic kidney disease. Journal of Science and Medicine in
Sport. 2013 Sep 30;16(5):406-11.
14. Barcellos FC, Santos IS, Umpierre D, et al.. Effects of exercise
in the whole spectrum of chronic kidney disease: a systematic 27. Beddhu S, Baird BC, Zitterkoph J, et al. Physical activity and
review. Clinical Kidney Journal. 2015 Oct 20;8(6):753-65. mortality in chronic kidney disease (NHANES III). Clinical
Journal of the American Society of Nephrology. 2009
15. Pei G, Tang Y, Tan L, et al. Aerobic exercise in adults with Dec 1;4(12):1901-6.
chronic kidney disease (CKD): a meta-analysis. International
Journal of Urology and Nephrology, 2019 Jul 22:1-9. 28. National Institute for Health and Care Excellence. London.
Chronic kidney disease in adults: assessment and
16. Kosmadakis GC, John SG, Clapp EL, et al. Benefits of management. 2014 NICE clinical guideline 182. (cited 2020 Aug
regular walking exercise in advanced pre-dialysis chronic 30) Available from: https://www.nice.org.uk/guidance/cg182
kidney disease. Nephrology Dialysis Transplantation. 2011 Jul
27;27(3):997-1004. 29. Renal Association. (2019). Clinical Practice Guideline –
Haemodialysis. (Cited 2020 Aug 30) Available at:
17. Viana JL, Kosmadakis GC, Watson EL, et al. Evidence for https://bmcnephrol.biomedcentral.com/articles/10.1186/
anti-inflammatory effects of exercise in CKD. Journal of the s12882-019-1527-3
American Society of Nephrology. 2014 Sep 1;25(9):2121-30.
30. KIDGO 2012 Clinical Practice Guideline for the Evaluation and
18. Headley SA, Germain MJ, Milch CM, et al. Immediate blood Management of Chronic Kidney Disease. International Society
pressure-lowering effects of aerobic exercise among patients of Nephrology. 2013;3(1):1-163
with chronic kidney disease. Nephrology. 2008 Oct 1;13(7):601-6.
31. Heiwe S. Ch 32. Kidney disease (chronic) and kidney transplant.
19 Mustata S, Groeneveld S, Davidson W, et al. Effects of exercise Swedish National Institute of Public Health. (2010) Physical
training on physical impairment, arterial stiffness and health- Activity in the prevention and treatment of disease. Cited 2020
related quality of life in patients with chronic kidney disease: Aug 30). Available at:
a pilot study. International Urology and Nephrology. 2011 Dec http://www.fyss.se/wp-content/uploads/2018/01/32.-Kidney-
1;43(4):1133-41. disease-chronic-and-kidney.pdf
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 69 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
32. Johansen KL. Exercise and chronic kidney disease. Sports 10. Pereira SM, Geoffroy MC, Power C. Depressive symptoms and
Medicine. 2005 Jun 1;35(6):485-99. physical activity during 3 decades in adult life: bidirectional
associations in a prospective cohort study. JAMA Psychiatry.
33. Greenwood SA, Naish P, Clark R, et al. Intra-dialytic exercise 2014 Dec 1;71(12):1373-80.
training: a pragmatic approach. Journal of Renal Care. 2014
Sep 1;40(3):219-26. 11. Dunn AL, Trivedi MH, Kampert JB, et al. Exercise treatment for
depression: efficacy and dose response. American Journal of
34. Smith AC, Burton JO. Exercise in kidney disease and diabetes: Preventive Medicine. 2005 Jan 31;28(1):1-8.
time for action. Journal of Renal Care. 2012 Feb 1;38(s1):52-8.
12. Stanton R, Reaburn P. Exercise and the treatment of
35. Smith AC, Burton JO. What I tell my patients about exercise. depression: a review of the exercise program variables. Journal
British Journal of Renal Medicine. 2014;19(1):15-8. of Science and Medicine in Sport. 2014 Mar 31;17(2):177-82.
2. Correll CU, Solmi M, Veronese N, et al. Prevalence, incidence 15. Callaghan P, Norman P. A Prospective Evaluation Of The
and mortality from cardiovascular disease in patients with Theory Of Planned Behaviour And Transtheoretical Model Of
pooled and specific severe mental illness: a large-scale meta- Change On Exercise In Young People. Psychology and Health.
analysis of 3,211,768 patients and 113,383,368 controls. World 2004 Jun 1;19:29-30.
Psychiatry. 2017 Jun 1;16(2):163-80.
16. Callaghan P, Khalil E, Morres I, Carter T. Pragmatic randomised
3. Compton MT, Daumit GL, Druss BG. Cigarette smoking and controlled trial of preferred intensity exercise in women living
overweight/obesity among individuals with serious mental with depression. BMC Public Health. 2011 Jun 12;11(1):465.
illnesses: a preventive perspective. Harvard Review of
Psychiatry. 2006 Jan 1;14(4):212-22. 17. National Institute for Health and Care Excellence. London
Depression in adults: recognition and management.
4. Mammen G, Faulkner G. Physical activity and the prevention NICE clinical guideline 90. 2016. (cited 2020 Jun 11)
of depression: a systematic review of prospective studies. Available from: https://www.nice.org.uk/guidance/cg90
American Journal of Preventive Medicine. 2013 Nov
30;45(5):649-57. Anxiety
1. United States Office of Disease Prevention and Health
5. McKercher C, Sanderson K, Schmidt MD, et al. Physical activity Promotion. Second Edition of Physical Activity Guidelines for
patterns and risk of depression in young adulthood: a 20-year Americans. 2018. (cited 2020 Jun 30) Available from:
cohort study since childhood. Social Psychiatry and Psychiatric https://health.gov/paguidelines/second-edition/
Epidemiology. 2014 Nov 1;49(11):1823-34.
2. American Psychiatric Association. Diagnostic and statistical
6. Schurch FB, Vancampfort D, Firth J, et al. Physical activity and manual of mental disorders (4th ed., text rev.). Arlington, VA:
Incident Depression: A meta-analysis of prospective cohort American Psychiatric Publishing; 2000.
studies. American Journal of Psychiatry. 2018 Jul 1;175(7):631-648
3. Ensari I, Greenlee TA, Motl RW, Petruzzello SJ. Meta-analysis
7. Cooney GM, Dwan K, Greig CA, et al. Exercise for depression. of acute exercise effects on state anxiety: an update of
Cochrane Database of Systematic Reviews. 2013, Issue 9. Art. randomized controlled trials over the past 25 years. Depress
No.: CD004366. DOI: 10.1002/14651858.CD004366.pub6. Anxiety. 2015;32(8):624-634. doi:10.1002/da.22370.
8. Rebar AL, Stanton R, Geard D, et al. A meta-meta-analysis of 4. Rebar AL, Stanton R, Geard D, et al. A meta-meta-analysis of
the effect of physical activity on depression and anxiety in the effect of physical activity on depression and anxiety in
non-clinical adult populations. Health Psychology Review. 2015 non-clinical adult populations. Health Psychology Review. 2015
Aug 7;9(3):366-78. Aug 7;9(3):366-78.
9. Schuch FB, Deslandes AC, Stubbs B, et al. Neurobiological 5. Stubbs B, Vancampfort D, Rosenbaum S, et al. An examination
effects of exercise on major depressive disorder: a systematic of the anxiolytic effects of exercise for people with anxiety
review. Neuroscience and Biobehavioral Reviews. 2016 Feb and stress-related disorders: a meta-analysis. Psychiatry Res.
29;61:1-11. 2017;49:102-108. doi:10.1016/j.psychres.2016.12.020.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 70 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
6. Wegner M, Helmich I, Machado S, et al. Effects of exercise on 5. Firth J, Stubbs B, Rosenbaum S, et al. Aerobic exercise
anxiety and depression disorders: review of meta-analyses and improves cognitive functioning in people with schizophrenia:
neurobiological mechanisms. CNS Neurol Disord Drug Targets. a systematic review and meta-analysis. Schizophrenia Bulletin.
2014;13(6):1002-1014. 2016 Aug 12;43(3):546-56.
Post-traumatic stress disorder (PTSD) 6. Vancampfort D, Stubbs B, Ward PB, et al. Why moving more
1. Sumner JA, Kubzansky LD, Elkind MS, et al. Trauma Exposure should be promoted for severe mental illness. The Lancet
and Posttraumatic Stress Disorder Symptoms Predict Onset of Psychiatry. 2015 Apr 1;2(4):295.
Cardiovascular Events in Women. Circulation. 2015; 132(4):251–259
7. National Institute for Health and Care Excellence. London.
2. Kubzansky LD, Bordelois P, Jun HJ, et al. The weight of Psychosis and schizophrenia in adults: prevention and
traumatic stress: a prospective study of posttraumatic stress management. 2014 NICE clinical guideline 178. (cited 2020 Aug
disorder symptoms and weight status in women. JAMA 11) Available from: https://www.nice.org.uk/guidance/cg178
Psychiatry. 2014; 71(1):44–51.
Sleep
3. Rosenbaum S, Stubbs B, Ward PB, et al. The prevalence and 1. Carsakadon MA, Dement WC. Monitoring and staging human
risk of metabolic syndrome and its components among people sleep. In Kryger MH, Roth T, Dement WC. Principles and practice
with posttraumatic stress disorder: a systematic review and of sleep medicine, 5th ed St. Louis: Elsevier Saunders; 2017.
meta-analysis. Metabolism. 2015; 64(8):926–933.
2. Office of Disease Prevention and Health Promotion. Sleep
4. Hall KS, Hoerster KD, Yancy WS Jr. Post-traumatic stress health. Washington, DC: Office of Disease Prevention and
disorder, physical activity, and eating behaviors. Epidemiol Rev. Health Promotion; 2017.
2015; 37(1):103–115. https://www.healthypeople.gov/2020/topics-objectives/topic/
sleep-health
5. Winning A, Gilsanz P, Koernen KC, et al. Post-traumatic stress
disorder and 20-Yr physical activity trends amongst women. 3. Mukherjee S, Patel SR, Kales SN, et al. An official American
Am J Prev Med. 2017 June; 52(6): 753-760 Thoracic Society statement: the importance of healthy sleep.
Recommendations and future priorities. Am J Respir Crit Care
6. Rosenbaum S, Vancampfort D, Steel Z, et al. Physical activity Med. 2015;191(12):1450-1458.
in the treatment of Post-traumatic stress disorder: a systematic
review and meta-analysis. Psychiatry Res. 2015;230(2):130-136. 4. United States Office of Disease Prevention and Health
Promotion. Second Edition of Physical Activity Guidelines for
7. United States Office of Disease Prevention and Health Americans. 2018. (cited 2020 May 30) Available from:
Promotion. Second Edition of Physical Activity Guidelines for https://health.gov/paguidelines/second-edition/
Americans. 2018. (cited 2020 Jun 30) Available from:
https://health.gov/paguidelines/second-edition/ 5. Kredlow MA, Capozzoli MC, Hearon BA, et al. The effects of
physical activity on sleep: a meta-analytic review. J Behav Med.
Schizophrenia 2015;38(3):427-449.
1. De Hert M, Dekker JM, Wood D, et al.. Cardio vascular disease
and diabetes in people with severe mental illness position Wellbeing and quality of life
statement from the European Psychiatric Association (EPA), 1. Warburton DE, Katzmarzyk PT, Rhodes RE, Shephard RJ.
supported by the European Association for the Study of Evidence-informed physical activity guidelines for Canadian
Diabetes (EASD) and the European Society of Cardiology adults. Applied Physiology, Nutrition and Metabolism. 2007
(ESC). European Psychiatry. 2009 Sep 30;24(6):412-24. Nov 14;32(S2E):S16-68.
2. Compton MT, Daumit GL, Druss BG. Cigarette smoking and 2. Gill TM, Feinstein AR. A critical appraisal of the quality of
overweight/obesity among individuals with serious mental quality-of-life measurements. JAMA. 1994;272(8):619-626.
illnesses: a preventive perspective. Harvard Review of
Psychiatry. 2006 Jan 1;14(4):212-22. 3. Diener E. Subjective wellbeing. Psychol Bull.
1984;95(3):542–575.
3. Vera-Gardia E, Mayoral-Cleries F, Vacampfort D et al. A
systematic review of the benefits of physical therapy within a 4. Ware JE Jr, Sherbourne CD. The MOS 36-item short-form
multidisciplinary care approach for people with schizophrenia; health survey (SF-36). Conceptual framework and item
an update. Psychiatry Res. 2015;229(30:828-839 selection. Med Care. 1992;30(6):473–483.
4. Firth J, Cotter J, Elliott R, et al. A systematic review and meta- 5. United States Office of Disease Prevention and Health
analysis of exercise interventions in schizophrenia patients. Promotion. Second Edition of Physical Activity Guidelines for
Psychological Medicine. 2015 May;45(7):1343-61. Americans. 2018. (cited 2020 May 30) Available from:
https://health.gov/paguidelines/second-edition/
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 71 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
6. Cho J, Martin P, Poon LW. Successful aging and subjective 12. Saxena S, Van Ommeren M, Tang KC, Armstrong TP. Mental
wellbeing among oldest-old adults. health benefits of physical activity. Journal of Mental Health.
Gerontologist. 2015;55(1):132–143. 2005 Jan 1;14(5):445-51.
Dementia 13. Weuve J, Kang JH, Manson JE, Breteler MM, Ware JH,
1. Alzheimers society report on dementia in the UK. (cited 2020 Grodstein F. Physical activity, including walking, and cognitive
Aug 16) Available from: function in older women. JAMA. 2004 Sep 22;292(12):1454-61.
https://www.alzheimers.org.uk/about-us/policy-and-
influencing/dementia-uk-report 14. National Institute for Health and Care Excellence. London.
Mental wellbeing and independence in older people: Public
2. Prince M, Wimo A, Guerchet M, et al. World Alzheimer health guideline 16. 2016 (cited 2020 Aug 16) Available from:
report 2015 – the global impact of dementia: an analysis of https://pathways.nice.org.uk/pathways/mental-wellbeing-
prevalence, incidence, cost and trends. London: Alzheimer’s and-independence-in-older-people
Disease International, 2015
15. Northey JM, Cherbuin N, Pampa Kl, et al. Exercise
3. Aarsland D, Sardahaee FS, Anderssen S, Ballard C and the interventions for cognitive function in adults over 50:
Alzheimer’s Society Systematic Review group. Is physical a systematic review with meta-analysis. British Journal
activity a potential preventive factor for vascular dementia? of Sports Medicine. Published Online First 24 April 2017
A systematic review. Aging and Mental Health. 2010 May doi:10.1136/bjsports-2016-096587.
1;14(4):386-95.
16. Young J, Angevaren M, Rusted J, Tabet N. Aerobic exercise
4. Livingston G, Somerlad A, Orgeta, et al. Dementia prevention, to improve cognitive function in older people without known
intervention, and care. The Lancet Commissions. cognitive impairment. The Cochrane Library. 2015 Apr 22.
Published online July 20, 2017 (cited 2020 Aug 16)
http://dx.doi.org/10.1016/S0140-6736(17)31363-6 17. Sabia S, Dugravot A, Dartigues JF, et al. Physical activity,
cognitive decline, and risk of dementia: 28 year follow-up of
5. O’Donovan G, Blazevich AJ, Boreham C, et al. The ABC of Whitehall II cohort study. BMJ. 2017 Jun 22;357:j2709
Physical Activity for Health: a consensus statement from the
British Association of Sport and Exercise Sciences. Journal of 18. Sink KM, Espeland MA, Castro CM, et al. Effect of a 24-month
Sports Sciences. 2010 Apr 1;28(6):573-91. physical activity intervention vs health education on cognitive
outcomes in sedentary older adults: the LIFE randomized
6. Helbastad JL, Taraldsen K, Saltvedt I. Ch 23 Dementia. Swedish trial. JAMA. 2015 Aug 25;314(8):781-90.
National Institute of Public Health. Physical Activity in the
prevention and treatment of disease. 2010. (cited 2020 Aug 16) 19. Snowden M, Steinman L, Mochan K, et al. Effect of exercise
Available from: on cognitive performance in community-dwelling older
http://www.fyss.se/wp-content/uploads/2018/01/23.- adults: review of intervention trials and recommendations for
Dementia.pdf public health practice and research. Journal of the American
Geriatrics Society. 2011 Apr 1;59(4):704-16.
7. Blondell SJ, Hammersley-Mather R, Veerman JL. Does physical
activity prevent cognitive decline and dementia?: A systematic 20. Andrieu S, Guyonnet S, Coley N, et al. Effect of long-term
review and meta-analysis of longitudinal studies. BMC Public omega 3 polyunsaturated fatty acid supplementation with
Health. 2014 May 27;14(1):510. or without multidomain intervention on cognitive function
in elderly adults with memory complaints (MAPT): a
8. Baumgart M, Snyder HM, Carrillo MC, et al. Summary of the randomised, placebo-controlled trial. The Lancet Neurology.
evidence on modifiable risk factors for cognitive decline 2017 May31;16(5):377-89.
and dementia: a population-based perspective. Alzheimer’s
Dementia. 2015 Jun 30;11(6):718-26. 21. Leckie RL, Oberlin LE, Voss MW, et al. DNF mediates
improvements in executive function following a 1-year
9. Norton S, Matthews FE, Barnes DE, et al. Potential for primary exercise intervention. Frontiers in Human Neuroscience.
prevention of Alzheimer’s disease: an analysis of population- 2014;8.
based data. The Lancet Neurology. 2014 Aug 31;13(8):788-94.
22. Brown BM, Peiffer JJ, Martins RN. Multiple effects of physical
10. Ahlskog JE, Geda YE, Graff-Radford NR, Petersen RC. Physical activity on molecular and cognitive signs of brain aging:
exercise as a preventive or disease-modifying treatment of can exercise slow neurodegeneration and delay Alzheimer’s
dementia and brain aging. In Mayo Clinic Proceedings 2011 Sep disease? Molecular Psychiatry. 2013 Aug 1;18(8):864.
30 (Vol. 86, No. 9, pp. 876-884). Elsevier.
23. Jensen CS, Hasselbalch SG, Waldemar G, Simonsen
11. Sofi F, Valecchi D, Bacci D, et al. Physical activity and risk of AH. Biochemical markers of physical exercise on mild
cognitive decline: a meta-analysis of prospective studies. cognitive impairment and dementia: systematic review and
Journal of Internal Medicine. 2011 Jan 1;269(1):107-17. perspectives. Frontiers in Neurology. 2015;6.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 72 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
24. GCBH. The brain–body connection: GCBH recommendations 3. Hu G, et al. Physical activity, body mass index, and risk
on physical activity and brain health. Washington, DC: Global of type 2 diabetes in patients with normal or impaired
Council on Brain Health, 2016. glucose regulation. Archives of Internal Medicine. 2004 Apr
26;164(8):892-6.
25. Groot C, Hooghiemstra AM, Raijmakers PG, et al. The effect
of physical activity on cognitive function in patients with Non-alcoholic fatty liver disease (NAFL)
dementia: a meta-analysis of randomized control trials. Ageing 1. Croci I, et al. Non-alcoholic fatty liver disease: prevalence
Research Reviews. 2016 Jan 31;25:13-23. and all-cause mortality according to sedentary behaviour
and cardiorespiratory fitness. The HUNT Study. Progress in
26. Brett L, Traynor V, Stapley P. Effects of physical exercise on cardiovascular diseases, 2019. 62(2): p. 127-134.
health and wellbeing of individuals living with a dementia in
nursing homes: A systematic review. Journal of the American 2. Michel M and JM Schattenberg. Effectiveness of lifestyle
Medical Directors Association. 2016 Feb 1;17(2):104-16. interventions in NAFLD (nonalcoholic fatty liver disease)–how
are clinical trials affected? 2020, Taylor & Francis.
27. Forbes D, Thiessen EJ, Blake CM, et al. Exercise programs
for people with dementia. Cochrane Database of Systematic 3. Thorp A and JG Stine. Exercise as Medicine: The Impact of
Reviews 2015, Issue 4. Art. No.: CD006489. Exercise Training on Nonalcoholic Fatty Liver Disease. Current
Hepatology Reports, 2020: p. 1-10.
28. Farina N, Rusted J, Tabet N. The effect of exercise interventions
on cognitive outcome in Alzheimer’s disease: a systematic 4. Kim D, et al. Physical activity, measured objectively, is associated
review. International Psychogeriatrics. 2014 Jan;26(1):9-18. with lower mortality in patients with nonalcoholic fatty liver
disease. Clinical Gastroenterology and Hepatology, 2020.
29. Öhman H, Savikko N, Strandberg TE, et al. Effects of exercise
on cognition: the Finnish Alzheimer disease exercise trial: a 5. Katsagoni CN, et al. Effects of lifestyle interventions on
randomized, controlled trial. Journal of the American Geriatrics clinical characteristics of patients with non-alcoholic fatty
Society. 2016 Apr 1;64(4):731-8. liver disease: A meta-analysis. Metabolism, 2017. 68: p. 119-132.
30. Pitkälä KH, Pöysti MM, Laakkonen ML, et al. Effects of 6. Huber Y, et al. Improvement of non-nvasive markers of NAFLD
the Finnish Alzheimer disease exercise trial (FINALEX): a from an individualised, web-based exercise program. Alimentary
randomized controlled trial. JAMA Internal Medicine. 2013 May pharmacology & therapeutics, 2019. 50(8): p. 930-939.
27;173(10):894-901.
7. Maurice J and P Manousou. Non-alcoholic fatty liver disease.
31. Chan WC, Yeung JW, Wong CS ,et al. Efficacy of physical Clinical Medicine, 2018. 18(3): p. 245.
exercise in preventing falls in older adults with cognitive
impairment: a systematic review and meta-analysis. Journal 8. Wang S-t, et al., Physical activity intervention for non-diabetic
of the American Medical Directors Association. 2015 Feb patients with non-alcoholic fatty liver disease: a meta-analysis
1;16(2):149-54. of randomized controlled trials. BMC gastroenterology, 2020.
20(1): p. 1-12.
32. Sherrington C, Michaleff ZA, Fairhall N, et al. Exercise to
prevent falls in older adults: an updated systematic review and 9. Villareal DT, et al., Aerobic or resistance exercise, or both, in
meta-analysis. British Journal of Sports Medicine. 2016 Oct 4 dieting obese older adults. New England Journal of Medicine,
2017. 376(20): p. 1943-1955.
33. National Institute for Health and Care Excellence London.
Dementia: assessment, management and support for people 10. Villareal DT, et al., Concurrent aerobic plus resistance exercise
living with dementia and their carer. 2018. NICE guideline 97 versus aerobic exercise alone to improve health outcomes
(cited 2020 Aug 16) in paediatric obesity: a systematic review and meta-analysis.
Available from: https://www.nice.org.uk/guidance/ng97 British Journal of Sports Medicine, 2018. 52(3): p. 161-166.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 73 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
4. DeUgarte CM, et al. Prevalence of insulin resistance in the 17. Morgan CL, et al. Evaluation of adverse outcome in young
polycystic ovary syndrome using the homeostasis model women with polycystic ovary syndrome versus matched,
assessment. Fertility and sterility, 2005. 83(5): p. 1454-1460. reference controls: a retrospective, observational study. The
Journal of Clinical Endocrinology & Metabolism, 2012. 97(9): p.
5. Teede HJ, et al. Recommendations from the international 3251-3260
evidence-based guideline for the assessment and
management of polycystic ovary syndrome. Human Pre-Diabetes and type 2 diabetes
reproduction, 2018. 33(9): p. 1602-1618. 1. Jadhav RA, et al. Effect of Physical Activity Intervention in
Prediabetes: A Systematic Review With Meta-analysis. J. Phys.
6. Dunaif A, et al. Profound peripheral insulin resistance, Act. Health 2017; 14, 745–755
independent of obesity, in polycystic ovary syndrome.
Diabetes, 1989. 38(9): p. 1165-1174. 2. Smith AD, et al. Physical activity and incident type 2 diabetes
mellitus: a systematic review and dose–response meta-analysis
7. Almenning I, et al. Effects of high intensity interval training and of prospective cohort studies. Diabetologia 2016; 59, 2527–2545
strength training on metabolic, cardiovascular and hormonal
outcomes in women with polycystic ovary syndrome: a pilot 3. Tuomilehto J, et al. Prevention of type 2 diabetes mellitus by
study. PLoS One, 2015. 10(9): p. e0138793. changes in lifestyle among subjects with impaired glucose
tolerance. N. Engl. J. Med. 2001; 344, 1343–1350
8. Palomba S, et al. Structured exercise training programme
versus hypocaloric hyperproteic diet in obese polycystic ovary 4. Pan XR, et al. Effects of diet and exercise in preventing NIDDM
syndrome patients with anovulatory infertility: a 24-week pilot in people with impaired glucose tolerance. The Da Qing IGT
study. Human reproduction, 2008. 23(3): p. 642-650. and Diabetes Study. Diabetes Care 1997; 20, 537–44
9. Thomson RL, et al. The effect of a hypocaloric diet with 5. Ramachandran A, et al. The Indian Diabetes Prevention
and without exercise training on body composition, Programme shows that lifestyle modification and metformin
cardiometabolic risk profile, and reproductive function in prevent type 2 diabetes in Asian Indian subjects with impaired
overweight and obese women with polycystic ovary syndrome. glucose tolerance (IDPP-1). Diabetologia 2006; 49, 289–297
The Journal of Clinical Endocrinology & Metabolism, 2008.
93(9): p. 3373-3380. 6. Knowler WC, et al. Reduction in the incidence of type 2
diabetes with lifestyle intervention or metformin. N Engl J Med
10. Vigorito C, et al. Beneficial effects of a three-month structured 2002; 346, 393–403
exercise training program on cardiopulmonary functional
capacity in young women with polycystic ovary syndrome. 7. Lindström J, et al. Sustained reduction in the incidence of type
The Journal of Clinical Endocrinology & Metabolism, 2007. 2 diabetes by lifestyle intervention: follow-up of the Finnish
92(4): p. 1379-1384. Diabetes Prevention Study. Lancet Lond. Engl. 2006; 368,
1673–1679
11. Lim SS, et al. Lifestyle changes in women with polycystic ovary
syndrome. Cochrane Database of Systematic Reviews, 2019(3). 8. Diabetes Prevention Program Research Group et al. 10-year
follow-up of diabetes incidence and weight loss in the Diabetes
12. Bruner B, et al. Effects of exercise and nutritional counseling in Prevention Program Outcomes Study. Lancet Lond. Engl.
women with polycystic ovary syndrome. Applied physiology, 2009; 374, 1677–1686
nutrition, and metabolism, 2006. 31(4): p. 384-391.
9. Li G, et al. The long-term effect of lifestyle interventions to
13. Stener-Victorin E, et al. Low-frequency electroacupuncture prevent diabetes in the China Da Qing Diabetes Prevention
and physical exercise decrease high muscle sympathetic Study: a 20-year follow-up study. The Lancet. 2008; 371,
nerve activity in polycystic ovary syndrome. American Journal 1783–1789
of Physiology-Regulatory, Integrative and Comparative
Physiology, 2009. 10. Jenum AK, et al. Effects of dietary and physical activity
interventions on the risk of type 2 diabetes in South Asians:
14. Hoeger KM, et al. A randomized, 48-week, placebo-controlled meta-analysis of individual participant data from randomised
trial of intensive lifestyle modification and/or metformin controlled trials. Diabetologia 2019 62, 1337–1348
therapy in overweight women with polycystic ovary syndrome:
a pilot study. Fertility and sterility, 2004. 82(2): p. 421-429. 11. Haw JS, et al. Long-term Sustainability of Diabetes Prevention
Approaches: A Systematic Review and Meta-analysis of
15. Landay M, et al. Degree of hyperinsulinemia, independent of Randomized Clinical Trials. JAMA Intern. Med. 2017 177,
androgen levels, is an important determinant of the severity of 1808–1817
hirsutism in PCOS. Fertility and sterility, 2009. 92(2): p. 643-647.
12. Galaviz KI, et al. Global Diabetes Prevention Interventions:
16. Kite C, et al. Exercise, or exercise and diet for the management A Systematic Review and Network Meta-analysis of the Real-
of polycystic ovary syndrome: a systematic review and meta- World Impact on Incidence, Weight, and Glucose. Diabetes
analysis. Systematic reviews, 2019. 8(1): p. 1-28. Care 2018; 41, 1526–1534
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 74 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
13. Hamman RF, et al. Effect of weight loss with lifestyle Type 1 Diabetes
intervention on risk of diabetes. Diabetes Care 2006; 29, 1. Chimen M, et al. What are the health benefits of physical
2102–2107 activity in type 1 diabetes mellitus? A literature review.
Diabetologia. 2012;55(3):542-551.
14. Colberg SR, et al. Physical Activity/Exercise and Diabetes:
A Position Statement of the American Diabetes Association. 2. Codella R, et al. Why should people with type 1 diabetes
Diabetes Care 2016; 39, 2065–2079 exercise regularly? Acta Diabetol. 2017;54(7):615-630.
15. Pan B, et al. Exercise training modalities in patients with type 3. Quirk H, et al. Physical activity interventions in children and
2 diabetes mellitus: a systematic review and network meta- young people with Type 1 diabetes mellitus: A systematic
analysis. Int. J. Behav. Nutr. Phys. Act. 2018; 15, 72 review with meta-analysis. Diabet Med. 2014;31(10):1163-1173.
16. Chudyk A & Petrella RJ. Effects of Exercise on Cardiovascular 4. Bohn B, et al. Impact of Physical Activity on Glycemic Control
Risk Factors in Type 2 Diabetes: A meta-analysis. Diabetes Care and Prevalence of Cardiovascular Risk Factors in Adults
2011; 34, 1228–1237 With Type 1 Diabetes: A Cross-sectional Multicenter Study of
18,028 Patients. Diabetes Care. 2015;38(8):1536-1543.
17. Snowling NJ & Hopkins WG. Effects of Different Modes of
Exercise Training on Glucose Control and Risk Factors for 5. Riddell MC, et al. Exercise management in type 1 diabetes:
Complications in Type 2 Diabetic Patients: A meta-analysis. a consensus statement. Lancet Diabetes Endocrinol.
Diabetes Care 2006; 29, 2518–2527 2017;8587(17):1-14.
18. Qiu S, et al. Exercise training and endothelial function in 6. Moser O, et al. Type 1 Diabetes and Physical Exercise: Moving
patients with type 2 diabetes: a meta-analysis. Cardiovasc. (forward) as an Adjuvant Therapy. Curr Pharm Des. 2020;26.
Diabetol. 2018; 17, 64
7. Colberg SR, et al. Physical Activity/Exercise and Diabetes:
19. Montero D, et al. Effects of exercise training on arterial function A Position Statement of the American Diabetes Association.
in type 2 diabetes mellitus: a systematic review and meta- Diabetes Care. 2016;39(11):2065-2079.
analysis. Sports Med. Auckl. NZ 2013; 43, 1191–1199
8. Adolfsson P, et al. ISPAD Clinical Practice Consensus
20. Munan M, et al. Acute and Chronic Effects of Exercise on Guidelines 2018: Exercise in children and adolescents with
Continuous Glucose Monitoring Outcomes in Type 2 Diabetes: diabetes. Published online 2018. doi:10.1111/pedi.12755
A Meta-Analysis. Front. Endocrinol. 2020; 11,
9. Brazeau A-S, et al. Barriers to physical activity
21. Sigal RJ, et al. Physical Activity and Diabetes. Can. J. Diabetes among patients with type 1 diabetes. Diabetes Care.
2018; 42, S54–S63 2008;31(11):2108-2109.
22. Hordern MD, et al. Exercise prescription for patients with type 2 10. Plotnikoff RC, et al. Factors associated with physical activity
diabetes and pre-diabetes: A position statement from Exercise in Canadian adults with diabetes. Med Sci Sports Exerc.
and Sport Science Australia. J. Sci. Med. Sport 2012; 15, 25–31 2006;38(8):1526-1534.
23. Gordon BA. Resistance training improves metabolic health in 11. Cisternas NS. ACSM Guidelines for Exercise Testing and
type 2 diabetes: A systematic review. Diabetes Res. Clin. Pract. Prescription. Tenth Edit. (Deborah R, Jonathan KE, Liguori G,
2009; 83, 157–175 Magal M, eds.). Wolters Kluwer Health; 2018.
24. Yang Z, et al. Resistance Exercise Versus Aerobic Exercise 12. Riddell MC, Burr J. Evidence-based risk assessment and
for Type 2 Diabetes: A Systematic Review and Meta-Analysis. recommendations for physical activity clearance: Diabetes
Sports Med. 2014; 44, 487–499 mellitus and related comorbidities. Appl Physiol Nutr Metab.
2011;36(SUPPL.1):154-189.
25. Sigal RJ, et al. Effects of aerobic training, resistance training, or
both on glycemic control in type 2 diabetes: a randomized trial. 13. Wadén J, et al. Leisure-time physical activity and
Ann. Intern. Med. 2007; 147, 357–369 development and progression of diabetic nephropathy
in type 1 diabetes: the FinnDiane Study. Diabetologia.
26. National Institute for Health and Care Excellence. London. 2015;58(5):929-936.
Type2 diabetes: prevention in people at high risk: NICE Public
Health guideline 38. 2017. (cited 2020 Aug 26). Available from: 14. Galassetti P, et al. Effect of differing antecedent
https://www.nice.org.uk/Guidance/PH38 hypoglycemia on counterregulatory responses to
exercise in type 1 diabetes. Am J Physiol Metab.
27 Riddell MC, Gallen IW, Smart CE, et al. Exercise management 2006;290(6):E1109-E1117.
in type 1 diabetes: a consensus statement. Lancet Diabetes
Endocrinol. 2017 May;5(5):377-390
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 75 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
15. Graveling AJ, Frier BM. Risks of marathon running and hypo- 28. Riddell MC, Milliken J. Preventing exercise-induced
glycaemia in Type 1 diabetes. Diabet Med. 2010;27(5):585-588. hypoglycemia in type 1 diabetes using real-time continuous
glucose monitoring and a new carbohydrate intake algorithm:
16. McCarthy O, et al. Glycemic responses to strenuous An observational field study. Diabetes Technol Ther.
training in male professional cyclists with type 1 diabetes: a 2011;13(8):819-825.
prospective observational study. BMJ Open Diabetes Res Care.
2020;8(1):e001245. 29. Moser O, et al. Effects of High-Intensity Interval Exercise
versus Moderate Continuous Exercise on Glucose
17. Scott S, et al. Carbohydrate Intake in the Context of Exercise in Homeostasis and Hormone Response in Patients with Type 1
People with Type 1 Diabetes. Nutrients. 2019;11(12):3017. Diabetes Mellitus Using Novel Ultra-Long-Acting Insulin.
PLoS One. 2015;10(8):e0136489.
18. Campbell MD, et al. A Low–Glycemic Index Meal and Bedtime
Snack Prevents Postprandial Hyperglycemia and Associated 30. Franc S, et al. Insulin-based strategies to prevent
Rises in Inflammatory Markers, Providing Protection From hypoglycaemia during and after exercise in adult patients
Early but Not Late Nocturnal Hypoglycemia Following Evening with type 1 diabetes on pump therapy: the DIABRASPORT
Exercise in Type 1 Diabetes. Diabetes Care. 2014;37(7):1845-1853. randomized study. Diabetes, Obes Metab. 2015;17(12):1150-1157.
19. Campbell MD, et al. Insulin therapy and dietary adjustments to 31. Tsalikian E, et al. Prevention of hypoglycemia during exercise
normalize glycemia and prevent nocturnal hypoglycemia after in children with type 1 diabetes by suspending basal insulin.
evening exercise in type 1 diabetes: A randomized controlled Diabetes Care. 2006;29(10):2200-2204.
trial. BMJ Open Diabetes Res Care. 2015;3(1):1-10.
32. Yardley JE. The Acute Effects of Aerobic and Resistance
20. West DJ, et al. A combined insulin reduction and carbohydrate Exercise on Blood Glucose Levels in Type 1 Diabetes.
feeding strategy 30 min before running best preserves blood Published online 2011. Accessed January 8, 2018.
glucose concentration after exercise through improved https://ruor.uottawa.ca/bitstream/10393/20031/5/Yardley_
fuel oxidation in type 1 diabetes mellitus. J Sports Sci. Jane_Elizabeth_2011_thesis.pdf
2011;29(3):279-289.
33. Turner D, et al. Algorithm that delivers an individualized rapid-
21. Gomez AM, et al. Effects of Performing Morning Versus acting insulin dose after morning resistance exercise counters
Afternoon Exercise on Glycemic Control and Hypoglycemia post-exercise hyperglycaemia in people with Type 1 diabetes.
Frequency in Type 1 Diabetes Patients on Sensor-Augmented Diabet Med. 2016;33(4):506-510.
Insulin Pump Therapy. J Diabetes Sci Technol. 2015;9(3):619-624.
34. Yardley JE, et al. Performing resistance exercise before versus
22. Bally L, et al. Metabolic and hormonal response to intermittent after aerobic exercise influences growth hormone secretion in
high-intensity and continuous moderate intensity exercise in type 1 diabetes. Appl Physiol Nutr Metab. 2014;39(2):262-265.
individuals with type 1 diabetes: a randomised crossover study.
Diabetologia. 2016;59(4):776-784. 35. Yardley JE, et al. Effects of Performing Resistance Exercise
Before Versus After Aerobic Exercise on Glycemia in Type 1
23. Tsalikian E, et al.Impact of Exercise on Overnight Glycemic Diabetes. Diabetes Care. 2012;35(4):669-675.
Control in Children with Type 1 Diabetes Mellitus. J Pediatr.
2005;147(4):528-534. 36. Bolinder J, et al. Novel glucose-sensing technology and
hypoglycaemia in type 1 diabetes: a multicentre, non-masked,
24. West DJ, et al. Isomaltulose improves postexercise glycemia randomised controlled trial. Lancet. 2016;388(10057):2254-2263.
by reducing CHO oxidation in T1DM. Med Sci Sports Exerc.
2011;43(2):204-210. 37. Adolfsson P, et al. Continuous glucose monitoring system
during physical exercise in adolescents with type 1 diabetes.
25. Riddell MC, et al. Individual glucose responses to prolonged Acta Paediatr. 2011;100(12):1603-1609.
moderate intensity aerobic exercise in adolescents with type
1 diabetes: The higher they start, the harder they fall. Pediatr 38. Bally L, et al. Accuracy of continuous glucose monitoring
Diabetes. 2018;20(1):pedi.12799. during differing exercise conditions. Diabetes Res Clin Pract.
2016;112:1-5.
26. Moser O, et al. Pre-exercise blood glucose levels determine the
amount of orally administered carbohydrates during physical 39. Moser O, et al. Performance of the Freestyle Libre flash
exercise in individuals with type 1 diabetes—a randomized glucose monitoring (flash GM) system in individuals with type
cross-over trial. Nutrients. 2019;11(6). 1 diabetes: A secondary outcome analysis of a randomized
crossover trial. Diabetes, Obes Metab. 2019;21(11):2505-2512.
27. McCarthy O, et al. Extent and prevalence of post-exercise and
nocturnal hypoglycemia following peri-exercise bolus insulin
adjustments in individuals with type 1 diabetes. Nutr Metab
Cardiovasc Dis. Published online August 6, 2020. doi:10.1016/j.
numecd.2020.07.043
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 76 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
Chapter 8 Physical Activity and Musculoskeletal health – 13. Fransen M, McConnell S, Hernandez-Molina G, Reichenbach
Fibromyalgia, Osteoarthritis and Osteoporosis S. Exercise for osteoarthritis of the hip. Cochrane Database
of Systematic Reviews 2014, Issue 4. Art. No.: CD007912.
1. Pedersen BK, Saltin B. Evidence for prescribing exercise as DOI: 10.1002/14651858.CD007912.pub2.
therapy in chronic disease. Scandinavian Journal of Medicine
and Science in Sports. 2006 Feb 1;16(S1):3-63. 14. Pendleton A, Arden N, Dougados M, et al. EULAR
recommendations for the management of knee
2. Bennett RM, Clark SR, Goldberg L, et al. Aerobic fitness in osteoarthritis: report of a task force of the Standing
patients with fibrositis. A controlled study of respiratory gas Committee for International Clinical Studies Including
exchange and 133xenon clearance from exercising muscle. Therapeutic Trials (ESCISIT). Annals of the Rheumatic
Arthritis and Rheumatology. 1989 Apr 1;32(4):454-60. Diseases. 2000 Dec 1;59(12):936-44.
3. Clark SR, Burckhardt CS, Campbell S, et al. Fitness characteristics 15. Juhl C, Christensen R, Roos EM, Zhang W, Lund H. Impact
and perceived exertion in women with fibromyalgia. Journal of of Exercise Type and Dose on Pain and Disability in Knee
Musculoskeletal Pain. 1993 Jan 1;1(3-4):191-7. Osteoarthritis: A Systematic Review and Meta-Regression
Analysis of Randomized Controlled Trials. Arthritis and
4. Clark SR. Prescribing exercise for fibromyalgia patients. Rheumatology. 2014 Mar 1;66(3):622-36.
Arthritis and Rheumatology. 1994 Dec 1;7(4):221-5.
16. Zhang W, Nuki G, Moskowitz RW, et al. OARSI
5. Rossy LA, Buckelew SP, Dorr N, et al. A meta-analysis of recommendations for the management of hip and knee
fibromyalgia treatment interventions. Annals of Behavioural osteoarthritis: part III: Changes in evidence following
Medicine. 1999 Jun 1;21(2):180-91. systematic cumulative update of research published through
January 2009. Osteoarthritis and Cartilage. 2010
6. Häuser W, Klose P, Langhorst J, et al.. Efficacy of different Apr 30;18(4):476-99.
types of aerobic exercise in fibromyalgia syndrome: a
systematic review and meta-analysis of randomised controlled 17. Nüesch E, Dieppe P, Reichenbach S, et al.. All cause and
trials. Arthritis Research and Therapy. 2010 May 10;12(3):R79. disease specific mortality in patients with knee or hip
osteoarthritis: population based cohort study.
7. Busch AJ, Barber KA, Overend TJ, et al.. Exercise for BMJ. 2011 Mar 8;342
fibromyalgia. Cochrane Database of Systematic Reviews 2013,
Issue 12. Art. No.: CD010884. DOI: 10.1002/14651858. 18. Badley E. Inactivity, disability, and death are all inter
CD010884. liked. If you must watch a lot of television, move between
commercial breaks. Editorial 2014. BMJ.348.
8. Department of Health. Start Active, Stay Active. A report on
physical activity for health from the four home countries’ Chief 19. National Institute for Health and Care Excellence. London.
Medical Officers. 2011. (cited 2020 Aug 15) Available from: Osteoarthritis: Care and management: Clinical guideline 177.
http://www.dh.gov.uk/en/Publicationsandstatistics/ 2014. (cited 2020 Aug 15). Available at:
Publications/PublicationsPolicyAndGuidance/DH_128209 https://www.nice.org.uk/guidance/cg177
9. Roos E. Ch 37. Swedish National Institute of Public Health. 20. Vainionpää A, Korpelainen R, Leppäluoto J, Jämsä T.
Physical Activity in the prevention and treatment of disease. Effects of high-impact exercise on bone mineral density:
2010. (cited 2020 Aug 15) a randomized controlled trial in premenopausal women.
Available from: http://www.fyss.se/wp-content/ Osteoporosis International. 2005 Feb 1;16(2):191-7.
uploads/2018/01/37.-Osteoarthritis.pdf
21. Heinonen A, Kannus P, Sievänen H, et al.. Good Maintenance
10. Bennell KL, Dobson F, Hinman RS. Exercise in osteoarthritis: of High-Impact Activity-Induced Bone Gain by Voluntary,
moving from prescription to adherence. Best Practice and Unsupervised Exercises: An 8-Month Follow-up of a
Research Clinical Rheumatology. 2014 Feb 28;28(1):93-117. Randomized Controlled Trial. Journal of Bone and Mineral
Research. 1999 Jan 1;14(1):125-8.
11. Devos-Comby L, Cronan T, Roesch SC. Do exercise and self-
management interventions benefit patients with osteoarthritis 22. Heinonen A, Kannus P, Sievänen H, et al. Randomised
of the knee? A meta-analytic review. The Journal of controlled trial of effect of high-impact exercise on selected
Rheumatology. 2006 Apr 1;33(4):744-56. risk factors for osteoporotic fractures. The Lancet. 1996 Nov
16;348(9038):1343-7.
12. Fransen M, McConnell S, Harmer AR, et al. Exercise
for osteoarthritis of the knee. Cochrane Database of 23. Engelke K, Kemmler W, Lauber D, et al.. Exercise maintains
Systematic Reviews 2015, Issue 1. Art. No.: CD004376. DOI: bone density at spine and hip EFOPS: a 3-year longitudinal
10.1002/14651858.CD004376.pub3. study in early postmenopausal women. Osteoporosis
International. 2006 Jan 1;17(1):133-42.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 77 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
24. Farahmand BY, Persson PG, Michaëlsson K, et al.. Physical 6. Stavropoulos-Kalinoglou A, Metsios GS, Veldhuijzen van
activity and hip fracture: a population-based case-control Zanten JJ, et al. Individualised aerobic and resistance
study. International Journal of Epidemiology. 2000 Apr exercise training improves cardiorespiratory fitness and
1;29(2):308-14. reduces cardiovascular risk in patients with rheumatoid
arthritis. Ann Rheum Dis. 2013;72(11):1819-1825. doi:10.1136/
25. Howe TE, Shea B, Dawson LJ, et al. Exercise for preventing and annrheumdis-2012-202075
treating osteoporosis in postmenopausal women. Cochrane
Database of Systematic Reviews 2011, Issue 7. Art. No.: 7. Neuberger GB, Aaronson LS, Gajewski B, et al. Predictors
CD000333. DOI: 10.1002/14651858.CD000333.pub2. of exercise and effects of exercise on symptoms, function,
aerobic fitness, and disease outcomes of rheumatoid arthritis.
26. Warburton DE, Katzmarzyk PT, Rhodes RE, Shephard RJ. Arthritis Care Res. 2007;57(6):943-952. doi:10.1002/art.22903
Evidence-informed physical activity guidelines for Canadian
adults. Applied Physiology, Nutrition, and Metabolism. 2007 8. de Jong Z, Munneke M, Zwinderman A, et al. Is a Long-
Nov 14;32(S2E):S16-68 Term High-Intensity Exercise Program Effective and Safe in
Patients With Rheumatoid Arthritis?: Results of a Randomized
27. Gillespie LD, Robertson MC, Gillespie WJ, et al.. Interventions Controlled Trial. Arthritis Rheum. 2003;48(9):2415-2424.
for preventing falls in older people living in the community.
Cochrane Database of Systematic Reviews 2012, Issue 9. Art. 9. Public Health England. Muscle and bone strengthening and
No.: CD007146. DOI: 10.1002/14651858.CD007146.pub3. balance activities for general health benefit in adults and older
adults: Summary of a rapid review for the UK Chief Medical
28. National Institute for Health and Clare Excellence. London. Officers update of physical activity guidelines. London; 2018
Osteoporosis- prevention of fragility fractures: Clinical
knowledge summaries. March 2016 (cited 2020 Aug 15) 10. Pedersen BK, Saltin B. Exercise as medicine - Evidence for
Available from: https://cks.nice.org.uk/osteoporosis- prescribing exercise as therapy in 26 different chronic diseases.
prevention-of-fragility-fractures#!scenario:1 Scand J Med Sci Sport. 2015;25:1-72. doi:10.1111/sms.12581
29. Ribom EL, Piehlm-Aulin K. Ch 38. Osteoporosis. Swedish 11. ACSM’s Guidelines for Exercise Testing and Prescription.
National Institute of Public Health. Physical Activity in the 10th ed. Wolters Kluwer
prevention and treatment of disease. 2010. (cited 2020
Aug 15). Available from: http://www.fyss.se/wp-content/ 12. National Institute for Health and Care Excellence. London.
uploads/2018/01/38.-Osteoporosis.pdf Rheumatoid arthritis in adults: management: NICE Guideline
100. 2018. (cited 2020 Aug 15) Available from:
https://www.nice.org.uk/guidance/ng100
Chapter 8 Physical Activity and Musculoskeletal Health -
Rheumatoid Arthritis
1. Hakkinen A, Hannonen P, HakkinenK. Muscle strength in Chapter 8 Physical Activity and Musculoskeletal Health –
healthy people and in patients suffering from recent-onset Prevention of falls and fracture
inflammatory arthritis. Br J Rheumatol. 1995;34(4):355-360.
doi:10.1093/rheumatology/34.4.355 1. Howe TE, Rochester L, Neil F, et al. Exercise for improving
balance in older people. Cochrane Database of Systematic
2. Sokka T, Häkkinen A. Poor physical fitness and performance as Reviews 2011, Issue 11. Art. No.: CD004963. DOI:
predictors of mortality in normal populations and patients with 10.1002/14651858.CD004963.pub3.
rheumatic and other diseases. Clin Exp Rheumatol.
2008;26(5 SUPPL. 51). 2. Skelton DA, Mavroedi, A. How do muscle and bone
strengthening and balance activities (MBSBA) vary across
3. Summers GD, Deighton CM, Rennie MJ, Booth AH. the life course, and are there particular ages where MBSBA
Rheumatoid cachexia: A clinical perspective. Rheumatology. are most important? Journal of Frailty, Sarcopenia and Falls.
2008;47(8):1124-1131. doi:10.1093/rheumatology/ken146 2018;3(2):7484
4. Avina-Zubieta JA, Choi HK, Sadatsafavi M, et al. Risk of 3. Public Health England. Muscle and bone strengthening and
cardiovascular mortality in patients with rheumatoid arthritis: balance activities for general health benefit in adults and older
a meta-analysis of observational studies. Arthritis Rheum. adults: Summary of a rapid review for the UK Chief Medical
2008;59(12):1690-1697. Officers update of physical activity guidelines. London; 2018
5. Metsios GS, Stavropoulos-Kalinoglou A, Panoulas VF, et al. 4. Gillespie LD, Robertson MC, Gillespie WJ, et al. Interventions
Association of physical inactivity with increased cardiovascular for preventing falls in older people living in the community.
risk in patients with rheumatoid arthritis. Eur J Cardiovasc Prev Cochrane Database of Systematic Reviews 2012, Issue 9. Art.
Rehabil. 2009;16(2):188-194. No.: CD007146. DOI: 10.1002/14651858.CD007146.pub3.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 78 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
5. Sherrington C, Michaleff ZA, Fairhall N, et al. Exercise to prevent 9. Department of Health. Start Active, Stay Active. A report on
falls in older adults: an updated systematic review and meta- physical activity for health from the four home countries’ Chief
analysis. British Journal of Sports Medicine. 2017: 51: 1750-1758 Medical Officers. 2011. (cited 2020 Aug 16) Available from:
http://www.dh.gov.uk/en/Publicationsandstatistics/
6. Sherrington C, Fairhall NJ, Wallbank GK, et al. Exercise for Publications/PublicationsPolicyAndGuidance/DH_128209
preventing falls in older people living in the community.
Cochrane Database of Systematic Reviews 2019, Issue 1. Art. 10. Shaw KA, Gennat HC, O’Rourke P, Del Mar C. Exercise
No.; CD012424. DOI: 10.1002/14651858.CD012424.pub2. for overweight or obesity. Cochrane Database of
Systematic Reviews 2006, Issue 4. Art. No: CD003817. DOI:
7. Chan WC, Yeung JW, Wong CS, et al. Efficacy of physical 10.1002/14651858.CD003817.pub3.
exercise in preventing falls in older adults with cognitive
impairment: a systematic review and meta-analysis. Journal 11. Swift DL, Johannsen NM, Lavie CJ, et al. The role of exercise
of the American Medical Directors Association. 2015 Feb and physical activity in weight loss and maintenance. Progress
1;16(2):149-54. in Cardiovascular Diseases. 2014 Feb 28;56(4):441-7.
8. Hunter GR, Wetzstein CJ, Fields DA, et al. Resistance training 12. Donnelly JE, Blair SN, Jakicic JM, et al. American College of
increases total energy expenditure and free-living physical Sports Medicine Position Stand. Appropriate physical activity
activity in older adults. Journal of Applied Physiology. 2000 intervention strategies for weight loss and prevention of
Sep 1;89(3):977-84. weight gain for adults. Medicine and Science in Sports and
Exercise.2009. 41(2): 459-71
9. National Institute for Health and Care Excellence. London.
Falls in older people: Assessing risk and prevention: Clinical 13. National Institute for Health and Care Excellence. London.
guideline 161. 2013. (cited 2020 Aug 15) Available from: Obesity: identification, assessment and management. 2014.
http://www.nice.org.uk/guidance/cg161 Clinical Guideline 189. (cited 2020 Aug 16) Available from:
https://www.nice.org.uk/guidance/cg189
Chapter 9: Physical Activity and Obesity 14. Winett RA, Carpinelli RN. Potential health-related benefits of
1. World Health Organization. Obesity and overweight. Fact resistance training. Preventive Medicine. 2001 Nov 1;33(5):503-13.
sheet 311. 2015. (cited 2020 Aug 16) Available from:
http://www.who.int/mediacentre/factsheets/fs311/en/ 15. Ruiz JR, Sui X, Lobelo F, et al. Association between muscular
strength and mortality in men: prospective cohort study. BMJ.
2. Campbell PT. Obesity: a certain and avoidable cause of cancer. 2008 Jan 1;337:a439.
The Lancet. 2014 Sep 5;384(9945):727-8.
16. Foster GD, Wadden TA, Vogt RA, Brewer G. What is a
3. Reilly JJ, Kelly J. Long-term impact of overweight and obesity reasonable weight loss? Patients’ expectations and evaluations
in childhood and adolescence on morbidity and premature of obesity treatment outcomes. Journal of Consulting and
mortality in adulthood: systematic review. International Journal Clinical Psychology. 1997 Feb;65(1):79-85
of Obesity. 2011 Jul 1;35(7):891.
17. Swift DL, Earnest CP, Blair SN, Church TS. The effect of
4. Griffiths LJ, Dezateux C, Hill A. Is obesity associated with different doses of aerobic exercise training on endothelial
emotional and behavioural problems in children? Findings from function in postmenopausal women with elevated blood
the Millennium Cohort Study. Pediatric Obesity. 2011 Jun;6(2- pressure: results from the DREW study. British Journal of
2):e423-32 Sports Medicine. 2012 Aug;46(10):753-8
5. Klein S, Burke LE, Bray GA, et al. Clinical implications of obesity 18. Kraus WE, Houmard JA, Duscha BD, et al. Effects of the
with specific focus on cardiovascular disease. Circulation. 2004 amount and intensity of exercise on plasma lipoproteins. New
Nov 2;110(18):2952-67. England Journal of Medicine. 2002 Nov 7;347(19):1483-92.
6. Wing RR, Lang W, Wadden TA, et al. Look AHEAD Research 19. Johannsen NM, Swift DL, Lavie CJ, et al. Categorical Analysis
Group. Benefits of modest weight loss in improving of the Impact of Aerobic and Resistance Exercise Training,
cardiovascular risk factors in overweight and obese individuals Alone and in Combination, on Cardiorespiratory Fitness Levels
with type 2 diabetes. Diabetes care. 2011 Jul 1;34(7):1481-6. in Patients With Type 2 Diabetes. Diabetes Care. 2013 Oct
1;36(10):3305-12.
7. Kritchevsky SB, Beavers KM, Miller ME, et al. Intentional weight
loss and all-cause mortality: a meta-analysis of randomized 20. Myers VH, McVay MA, Brashear MM, et al. Exercise training and
clinical trials. PLoS One. 2015 Mar 20;10(3):e0121993. quality of life in individuals with type 2 diabetes. Diabetes Care.
2013 Jul 1;36(7):1884-90.
8. Thomas DM, Bouchard C, Church T, et al. Why do individuals
not lose more weight from an exercise intervention at a defined 21. Martin CK, Church TS, Thompson AM, et al. Exercise dose and
dose? An energy balance analysis. Obesity Reviews. 2012 Oct quality of life: a randomized controlled trial. Archives of Internal
1;13(10):835-47. Medicine. 2009 Feb 9;169(3):269-78.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 79 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
22. King NA, Hopkins M, Caudwell P, et al. Beneficial effects of 10. Wu WH, Meijer OG, Uegaki K, et al. Pregnancy-related pelvic
exercise: shifting the focus from body weight to other markers girdle pain (PPP), I: Terminology, clinical presentation, and
of health. British Journal of Sports Medicine. 2009 Nov prevalence. European Spine Journal. 2004 Nov 1;13(7):575-89.
1;43(12):924-7.
11. Pelvic, Obstetric and Gynaecological Physiotherapy.
23. National Institute for Health and Care Excellence. London. Pregnancy-related Pelvic Girdle Pain: Guidance for Health
Public Health guidance 53. Managing overweight and obesity Professionals. 2015; POGPH. (cited 2020 Nov 18) View
in adults – lifestyle weight management services. 2014. document https://pogp.csp.org.uk/system/files/publication_
(cited 2020 Aug 16) Available from: files/POGP-PGP%28Pros%29.pdf
https://www.nice.org.uk/guidance/ph53
12. National Institute for Health and Care Excellence. Antenatal
care for uncomplicated pregnancies. 2019 Clinical guideline
Chapter 10: Physical Activity and Pregnancy CG62. (cited 2020 Nov 18) Available from:
1. UK Chief Medical Officers’ Physical Activity Guidelines. Physical https://www.nice.org.uk/Guidance/CG62
activity for pregnant women. 2019. (cited 2020 Nov 19) View
document information URL: https://assets.publishing.service. 13. UK Chief Medical Officers’ Physical Activity Guidelines. Physical
gov.uk/government/uploads/system/uploads/attachment_ activity for women after childbirth (birth to 12 months). 2019.
data/file/829894/5-physical-activity-for-pregnant-women.pdf (cited 2020 Nov 19) View website URL:
https://assets.publishing.service.gov.uk/government/uploads/
2. Birsner ML, Gyamfi-Bannerman C. Physical Activity and system/uploads/attachment_data/file/841936/Postpartum_
Exercise During Pregnancy and the Postpartum Period ACOG infographic.pdf
Committee Opinion Summary, Number 804. Obstet Gynecol.
2020 Apr 1;135(4):E178-88. 14. Department of Health and Social Care. Physical activity
guidelines: UK Chief Medical Officers’ report. 2019; London:
3. Rogozińska E, Marlin N, Jackson L, Bogaerts A. Effects of Crown copyright. (cited 2020 Nov 19) View website URL:
antenatal diet and physical activity on maternal and fetal https://www.gov.uk/government/publications/physical-
outcomes: individual patient data meta-analysis and health activity-guidelines-uk-chief-medical-officers-report
economic evaluation. Health Technology Assessment.
2017;21(41):1-94. 15. Bø K, Artal R, Barakat R, et al. (2017). Exercise and pregnancy in
recreational and elite athletes: 2016/17 evidence summary from
4. United States Office of Disease Prevention and Health the IOC expert group meeting, Lausanne. Part 3 – exercise in
Promotion. Second Edition of Physical Activity Guidelines for the postpartum period. Br J Sports Med, 51, 1516-1525
Americans. 2018. (cited 2020 Jun 30) Available from
https://health.gov/paguidelines/second-edition/ 16. Erdener U, Budgett R. Exercise and pregnancy: focus on
advice for the competitive and elite athlete. Br J Sports Med
5. Mottola MF, Davenport MH, Ruchat SM et al. 2019 Canadian 2016;50:567
guideline for physical activity throughout pregnancy.
Br J Sport Med . 2018;52:1339-1346 17. Staer-Jenson J, Siafarikas F, Hilde G, et al. Postpartum
recovery of levator hiatus and bladder neck mobility in relation
6. Daley AJ, Foster L, Long G, et al. The effectiveness of exercise to pregnancy. Obstet Gynecol 2015;125:531-9
for the prevention and treatment of antenatal depression:
systematic review with meta-analysis. BJOG: An International 18. Mihevc Edwards K. Considerations for the for the postpartum
Journal of Obstetrics and Gynaecology. 2015 Jan 1;122(1):57-62. runner. Strength and Conditioning Journal. 2020;42::45-52
7. Bø K, Artal R, Barakat R. et al. (2016). Exercise and pregnancy 19. Donnelly GM, Rankin A, Mills H, et al. Infographic. Guidance
in recreational and elite athletes: 2016 evidence summary from for medical, health and fitness professionals to support
the IOC expert group meeting, Lausanne. Part 2 - the effect women in returning to running postnatally. Br J Sports Med.
of exercise on the fetus, labour and birth. Br J Sports Med, 2020;54:1114-1115
50, 1297-1305.
8. Meah VL, Davies GA, Davenport MH. Why can’t I exercise Chapter 11: Physical Activity and Respiratory Disease
during pregnancy? Time to revisit medical ‘absolute’ and Asthma
‘relative’ contraindications: systematic review of evidence of 1. Eichenberger PA, Diener R, Kofmehl , Spengler CM. Effects
harm and a call to action. Br J Sports Med 2020;54:1395-1404 of exercise training on airway hyperactivity in asthma: a
systematic review and meta-analysis. Sports Med 2013. 43;
9. Hunskaar S, Burgio K, Clark A, et al. Epidemiology of urinary (11): 1157-70
(UI) and faecal (FI) incontinence and pelvic organ prolapse
(POP). Incontinence. 2005;1:255-312. 2. Carson KV, Chandratilleke MG, et al. Physical training for
asthma. Cochrane Database Systematic Reviews. 2013 (9):
CD009607
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 80 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
3. Beggs S, Foong YC, Le HC, et al.. Swimming training for 4. Waschki B, Kirsten AM, Holz O, et al. Disease Progression
asthma in children and adolescents aged 18 years and under. and Changes in Physical Activity in Patients with Chronic
Cochrane Database Syst Rev. 2013(4):CD009607 Obstructive Pulmonary Disease. Am J Respir Crit Care Med.
2015;192(3):295-306
4. Azizpour Y, Delpisheh A, Montazeri Z, et al. Effect of childhood
BMI on asthma: a systematic review and meta-analysis of case- 5. National Institute for Health and Care Excellence. Chronic
control studies. BMC Pediatr. 2018;18(1):143 obstructive pulmonary disease in over 16s: diagnosis and
management. NICE guideline NG115. 2019 (cited 2020 Aug 24)
5. Beuther DA, Sutherland ER. Overweight, obesity, and incident https://www.nice.org.uk/guidance/NG115
asthma: a meta-analysis of prospective epidemiologic studies.
Am J Respir Crit Care Med. 2007;175(7):661-6 6. Bolton CE, Bevan-Smith EF, Blakey JD, et al. British Thoracic
Society guideline on pulmonary rehabilitation in adults. Thorax.
6. Adeniyi FB, Young T. Weight loss interventions for chronic 2013;68 Suppl 2:ii1-30.
asthma. Cochrane Database Syst Rev. 2012(7):CD009339.
7. Spruit MA, Singh SJ, Garvey C, et al. An official American
7. Cordova-Rivera L, Gibson PG, Gardiner PA, McDonald VM. Thoracic Society/European Respiratory Society statement:
A Systematic Review of Associations of Physical Activity key concepts and advances in pulmonary rehabilitation. Am J
and Sedentary Time with Asthma Outcomes. J Allergy Clin Respir Crit Care Med. 2013;188(8):e13-64.
Immunol Pract. 2018
Cystic Fibrosis
8. Weiler JM, Brannan JD, Randolph CC,et al.. Exercise-induced 1. Schneiderman JE, Wilkes DL, Atenafu EG, et al. Longitudinal
bronchoconstriction update-2016. J Allergy Clin Immunol. relationship between physical activity and lung health in
2016;138(5):1292-5.e36. patients with cystic fibrosis. Eur Respir J. 2014;43(3):817-23
9. Bonini M, Di Mambro C, Calderon MA, et al. Beta2- agonists 2. Nixon PA, Orenstein DM, Kelsey SF, Doershuk CF. The
for exercise-induced asthma. Cochrane Database Syst Rev. prognostic value of exercise testing in patients with cystic
2013(10):CD003564 fibrosis. N Engl J Med. 1992;327(25):1785-8
10. Stickland MK, Rowe BH, Spooner CH, et al. Effect of warm-up 3. Castellani LN, Peppler WT, Miotto PM. Exercise Protects
exercise on exercise-induced bronchoconstriction. Med Sci Against Olanzapine-Induced Hyperglycemia in Male C57BL/6J
Sports Exerc. 2012;44(3):383-91 Mice. Sci Rep. 2018;8(1):772
11. Parsons JP, Hallstrand TS, Mastronarde JG, et al. An official 4. Radtke T, Nevitt SJ, Hebestreit H, Kriemler S. Physical exercise
American Thoracic Society clinical practice guideline: exercise- training for cystic fibrosis. Cochrane Database Syst Rev.
induced bronchoconstriction. Am J Respir Crit Care Med. 2017;11:CD002768
2013;187(9):1016-27
5. NICE guideline NG115. 2019. Cystic fibrosis: diagnosis and
12. Royal College of Physicians. National Review of Asthma management. NICE guideline [NG78]
Deaths, Why Asthma still kills? (cited 2020 Aug 30) https://www.nice.org.uk/guidance/ng78
https://www.rcplondon.ac.uk/projects/outputs/why-asthma-
still-kills 6. Pedersen BK, Saltin B. Exercise as medicine - evidence for
prescribing exercise as therapy in 26 different chronic diseases.
13. Pedersen BK, Saltin B. Exercise as medicine - evidence for Scand J Med Sci Sports. 2015;25 Suppl 3:1-72
prescribing exercise as therapy in 26 different chronic diseases.
Scand J Med Sci Sports. 2015;25 Suppl 3:1-72
Chapter 12: Physical Activity and Perioperative Surgery
Chronic Obstructive Pulmonary Disease 1. The UK Chief Medical Officers physical activity guidelines
1. GOLD. Global strategy for the diagnosis, management, and report 2019. (cited 2020 Aug 30) Available from:
prevention of chronic obstructive pulmonary disease: 2019 https://www.gov.uk/government/publications/physical-
report (cited 2020 Aug 30) activity-guidelines-uk-chief-medical-officers-report
https://goldcopd.org/wp-content/uploads/2018/11/GOLD-
2019-v1.6-FINAL-08Nov2018-wms.pdf 2. Pearse RM, Harrison DA, James P, et al. Identification and
characterisation of the high-risk surgical population in the
2. Watz H, Pitta F, Rochester CL, et al. An official European United Kingdom. Critical Care. 2006 Jun 2;10(3):R81.
Respiratory Society statement on physical activity in COPD.
Eur Respir J. 2014;44(6):1521-37. 3. Khuri SF, Henderson WG, DePalma RG, et al. Determinants of
long-term survival after major surgery and the adverse effect
3. McCarthy B, Casey D, Devane D, Pulmonary rehabilitation for of postoperative complications. Annals of Surgery. 2005
chronic obstructive pulmonary disease. Cochrane Database Sep;242(3):326-341
Syst Rev. 2015(2):CD003793.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 81 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
4. Girish M, Trayner E, Dammann O, et al. Symptom-limited stair 16. Singh F, Newton RU, Galvão DA, Spry N, Baker MK.
climbing as a predictor of postoperative cardiopulmonary A systematic review of pre-surgical exercise intervention
complications after high-risk surgery. Chest. 2001 Oct studies with cancer patients. Surgical Oncology. 2013 Jun
31;120(4):1147-51. 30;22(2):92-104.
5. Reilly DF, McNeely MJ, Doerner D, et al.. Self-reported exercise 17. West MA, Loughney L, Lythgoe D, et al. Effect of
tolerance and the risk of serious perioperative complications. prehabilitation on objectively measured physical fitness
Archives of Internal Medicine. 1999 Oct 11;159(18):2185-92. after neoadjuvant treatment in preoperative rectal cancer
patients: a blinded interventional pilot study. British Journal of
6. Lawrence VA, Hazuda HP, Cornell JE, et al. Functional Anaesthesia. 2014 Oct 1;114(2):244-51.
independence after major abdominal surgery in the elderly.
Journal of the American College of Surgeons. 2004 Nov 18. Schmid D, Leitzmann MF. Association between physical
30;199(5):762-72. activity and mortality among breast cancer and colorectal
cancer survivors: a systematic review and meta-analysis.
7. Older R, Smith R, Courtney B, Hone R. Preoperative Annals of Oncology. 2014 Mar 18;25(7):1293-311.
evaluation of cardiac failure and ischemia in elderly patients
by cardiopulmonary exercise testing. Chest. 1993 Sep 19. National Institute for Health and Care Excellence. London.
30;104(3):701-4. Lower limb peripheral arterial disease: diagnosis and
management: NICE clinical guideline 147. 2012.
8. Carlisle J, Swart M. Mid-term survival after abdominal aortic (cited 2020 Aug 30) Available from:
aneurysm surgery predicted by cardiopulmonary exercise https://www.nice.org.uk/guidance/cg147
testing. British Journal of Surgery. 2007 Aug 1;94(8):966-9.
20. Royal College of Anaesthetics. Patient leaflet . Fitter,
9. Datta D, Lahiri B. Preoperative evaluation of patients Better, Sooner. https://www.rcoa.ac.uk/sites/default/files/
undergoing lung resection surgery. Chest. 2003 Jun documents/2020-05/FitterBetterSooner2018web.pdf
30;123(6):2096-103.
10. Hennis PJ, Meale PM, Grocott MP. Cardiopulmonary exercise Chapter 13: Sedentary Behaviour
testing for the evaluation of perioperative risk in non- Part 1
cardiopulmonary surgery. Postgraduate Medical Journal. 2011 1. The UK Chief Medical Officers physical activity guidelines
Aug 1;87(1030):550-7. report 2019. (cited 2020 Aug 30) Available from:
https://www.gov.uk/government/publications/physical-
11. Snowden CP, Prentis JM, Anderson HL, et al. Submaximal activity-guidelines-uk-chief-medical-officers-report
cardiopulmonary exercise testing predicts complications and
hospital length of stay in patients undergoing major elective 2. Jakes RW, Day NE, Khaw KT, Luben R. Television viewing and
surgery. Annals of Surgery. 2010 Mar 1;251(3):535-41. low participation in vigorous recreation are independently
associated with obesity and markers of cardiovascular disease
12. Wilson RJ, Davies S, Yates D, Redman J, Stone M. Impaired risk: EPIC-Norfolk population-based study. European Journal
functional capacity is associated with all-cause mortality after of Clinical Nutrition. 2003 Sep 1;57(9):1089-1096.
major elective intra-abdominal surgery. British Journal of
Anaesthesia. 2010 Jun 23;105(3):297-303. 3. Hu FB, Leitzmann MF, Stampfer MJ, et al. Physical activity
and television watching in relation to risk for type 2 diabetes
13. West MA, Lythgoe D, Barben CP, et al. Cardiopulmonary mellitus in men. Archives of Internal Medicine. 2001 Jun
exercise variables are associated with postoperative 25;161(12):1542-8.
morbidity after major colonic surgery: a prospective blinded
observational study. British Journal of Anaesthesia. 2013 Dec 4. Bertrais S, Beyeme-Ondoua JP, Czernichow S, et al. Sedentary
8;112(4):665-71. behaviors, physical activity, and metabolic syndrome in
middle-aged French subjects. Obesity. 2005 May
14. Snowden CP, Prentis J, Jacques B, et al. Cardiorespiratory 1;13(5):936-44.
fitness predicts mortality and hospital length of stay after
major elective surgery in older people. Annals of Surgery. 5. Dunstan DW, Salmon J, Owen N, et al. Physical activity and
2013 Jun 1;257(6):999-1004. television viewing in relation to risk of undiagnosed abnormal
glucose metabolism in adults. Diabetes Care. 2004 Nov
15. Dronkers JJ, Chorus AM, Meeteren NL, Hopman-Rock M. 1;27(11):2603-9.
The association of pre-operative physical fitness and physical
activity with outcome after scheduled major abdominal 6. Katzmarzyk PT, Church TS, Craig CL, Bouchard C. Sitting time
surgery. Anaesthesia. 2013 Jan 1;68(1):67-73. and mortality from all causes, cardiovascular disease, and
cancer. Medicine & Science in Sports & Exercise. 2009 May
1;41(5):998-1005.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 82 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
7. Edwardson CL, Gorely T, Davies MJ, et al. Association of 19. Ekelund U, Steene-Johannessen J, Brown WJ, et al. Lancet
sedentary behaviour with metabolic syndrome: a meta- Sedentary Behaviour Working Group. Does physical activity
analysis. PloS ONE. 2012 Apr 13;7(4):e34916. attenuate, or even eliminate, the detrimental association of
sitting time with mortality? A harmonised meta-analysis of
8. Wen CP, Wai JP, Tsai MK, et al. Minimum amount of data from more than 1 million men and women. The Lancet.
physical activity for reduced mortality and extended life 2016 Sep 30;388(10051):1302-10.
expectancy: a prospective cohort study. The Lancet. 2011 Oct
7;378(9798):1244-53. 20. Schumacher M, Rücker G, Schwarzer G. Meta-analysis and the
Surgeon General’s report on smoking and health. New England
9. Lee IM, Shiroma EJ, Lobelo F, et al. Lancet Physical Activity Journal of Medicine. 2014 Jan 9;370(2):186-8.
Series Working Group. Effect of physical inactivity on major
non-communicable diseases worldwide: an analysis of 21. Prospective Studies Collaboration. Body-mass index and
burden of disease and life expectancy. The Lancet. 2012 Jul cause-specific mortality in 900 000 adults: collaborative
27;380(9838):219-29. analyses of 57 prospective studies. The Lancet. 2009 Apr
3;373(9669):1083-96.
10. Pearson N, Biddle SJ. Sedentary behavior and dietary intake in
children, adolescents, and adults: a systematic review. American 22. Kim Y, Wilkens LR, Park SY, et al. Association between various
Journal of Preventive Medicine. 2011 Aug 31;41(2):178-88. sedentary behaviours and all-cause, cardiovascular disease and
cancer mortality: the Multiethnic Cohort Study. International
11. Melkevik O, Torsheim T, Iannotti RJ, Wold B. Is spending time Journal of Epidemiology. 2013 Aug 1;42(4):1040-56.
in screen-based sedentary behaviors associated with less
physical activity: a cross national investigation. International Part 2
Journal of Behavioral Nutrition and Physical Activity. 2010 May 1. Barnes J, Behrens TK, Benden ME, et al. Letter to the Editor:
21;7(1):46. Standardized use of the terms” sedentary” and” sedentary
behaviours”. Applied Physiology Nutrition and Metabolism.
12. Foti KE, Eaton DK, Lowry R, McKnight-Ely LR. Sufficient sleep, 2012 Jun 1;37(3):540-2.
physical activity, and sedentary behaviors. American Journal of
Preventive Medicine. 2011 Dec 31;41(6):596-602. 2. Booth FW, Roberts CK, Laye MJ. Lack of exercise is a major
cause of chronic diseases. Comprehensive Physiology. 2012
13. Benatti FB, Ried-Larsen M. The effects of breaking up Apr 1;2:1143-1211.
prolonged sitting time: a review of experimental studies.
Medicine & Science in Sports & Exercise. 2015 Oct 3. Bloomfield SA. Changes in musculoskeletal structure and
1;47(10):2053-61. function with prolonged bed rest. Medicine and Science in
Sports and Exercise. 1997 Feb;29(2):197-206.
14. Harris JL, Bargh JA, Brownell KD. Priming effects of television
food advertising on eating behavior. Health Psychology. 2009 4. Arthritis Research UK (2013) Musculoskeletal health-A public
Jul;28(4):404-413 health approach. (cited 2020 Aug 30)
https://www.versusarthritis.org/media/2179/public-health-
15. Veerman JL, Healy GN, Cobiac LJ, et al. Television viewing guide.pdf
time and reduced life expectancy: a life table analysis. British
Journal of Sports Medicine. 2011 Aug 1; 46:927-30 5. Wittink H, Engelbert R, Takken T. The dangers of inactivity;
exercise and inactivity physiology for the manual therapist.
16. Henson J, Yates T, Biddle SJ, et al. Associations of objectively Manual Therapy. 2011 Jun 30;16(3):209-16.
measured sedentary behaviour and physical activity with
markers of cardiometabolic health. Diabetologia. 2013 May 6. Gianoudis J, Bailey CA, Daly RM. Associations between
1;56(5):1012-20. sedentary behaviour and body composition, muscle
function and sarcopenia in community-dwelling older adults.
17. Chau JY, Grunseit AC, Chey T, et al. Daily sitting time and Osteoporosis International. 2015 Feb 1;26(2):571-9.
all-cause mortality: a meta-analysis. PloS ONE. 2013 Nov
13;8(11):e80000 7. HSE. Work-related musculoskeletal disorder statistics, Great
Britain. Health and Safety executive. 2015. (cited 2020 Jun 30.
18. Biswas A, Oh PI, Faulkner GE, et al. Sedentary time and its Available from: https://www.qcs.co.uk/wp-content/
association with risk for disease incidence, mortality, and uploads/2015/12/Work-related-Musculoskeletal-Disorder-
hospitalization in adults: a systematic review and meta- WRMSDs.pdf
analysis sedentary time and disease incidence, mortality,
and hospitalization. Annals of Internal Medicine. 2015 Jan 8. Shiri R, Karppinen J, Leino-Arjas P, et al. The association
20;162(2):123-32. between obesity and low back pain: a meta-analysis. American
Journal of Epidemiology. 2009 Dec 11;171(2):135-54.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 83 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
9. Teichtahl AJ, Urquhart DM, Wang Y, et al. Physical inactivity is 22. Malliaras P, Barton CJ, Reeves ND, Langberg H. Achilles and
associated with narrower lumbar intervertebral discs, high fat patellar tendinopathy loading programmes. Sports Medicine.
content of paraspinal muscles and low back pain and disability. 2013 Apr 1;43(4):267-86.
Arthritis Research and Therapy. 2015 May 7;17(1):114.
23. Franceschi F, Papalia R, Paciotti M, et al. Obesity as a risk factor
10. Richmond H, Hall AM, Copsey B, et al. The effectiveness of for tendinopathy: a systematic review. International Journal of
cognitive behavioural treatment for non-specific low back pain: Endocrinology. 2014;2014:670262
a systematic review and meta-analysis. PloS ONE. 2015 Aug
5;10(8):e0134192. 24. Van der Worp H, van Ark M, Roerink S, Pepping GJ, et al. J.
Risk factors for patellar tendinopathy: a systematic review of
11. Kamper SJ, Apeldoorn AT, Chiarotto A, et al. Multidisciplinary the literature. British Journal of Sports Medicine. 2011 Mar 1: 45.
biopsychosocial rehabilitation for chronic low back pain: 446-452
Cochrane systematic review and meta-analysis. BMJ. 2015 Feb
18;350:h444. 25. National Institute for Health and Care Excellence. London.
Osteoarthritis: care and management: NICE Clinical guideline
12. Shiri R, Falah-Hassani K, Viikari-Juntura E, Coggon D. Leisure- 177. 2014. (cited 2020 Aug 30) Available from:
time physical activity and sciatica: A systematic review https://www.nice.org.uk/guidance/cg177
and meta-analysis. European Journal of Pain. 2016 Nov
1;20(10):1563-72. 26. Wallis JA, Webster KE, Levinger P, Taylor NF. What proportion
of people with hip and knee osteoarthritis meet physical
13. Shiri R, Karppinen J, Leino-Arjas P, et al. Cardiovascular and activity guidelines? A systematic review and meta-analysis.
lifestyle risk factors in lumbar radicular pain or clinically defined Osteoarthritis and Cartilage. 2013 Nov 30;21(11):1648-59.
sciatica: a systematic review. European Spine Journal. 2007
Dec 1;16(12):2043-54. 27. Russell S, Jariwala A, Conlon R, et al. A blinded, randomized,
controlled trial assessing conservative management strategies
14. Shiri R, Lallukka T, Karppinen J, Viikari-Juntura E. Obesity as for frozen shoulder. Journal of Shoulder and Elbow Surgery.
a risk factor for sciatica: a meta-analysis. American Journal of 2014 Apr 30;23(4):500-7.
Epidemiology. 2014 Feb 24;179(8):929-37.
28. Macías-Hernández SI, Morones-Alba JD, Miranda-Duarte
15. The UK Chief Medical Officers physical activity guidelines A, et al. Glenohumeral osteoarthritis: overview, therapy,
report 2019. (cited 2020 Aug 30) Available from: and rehabilitation. Disability and Rehabilitation. 2017 Jul
https://www.gov.uk/government/publications/physical- 31;39(16):1674-82.
activity-guidelines-uk-chief-medical-officers-report
29. Edwards P, Ebert J, Joss B, Bhabra G, et al. Exercise
16. Hayden J, Van Tulder MW, Malmivaara A, Koes BW. Exercise rehabilitation in the non-operative management of rotator cuff
therapy for treatment of non-specific low back pain. Cochrane tears: a review of the literature. International Journal of Sports
Database of Systematic Reviews 2005, Issue 3. Art. No.: Physical Therapy. 2016 Apr;11(2):279-301.
CD000335. DOI: 10.1002/14651858.CD000335.pub2.
30. Rechardt M, Shiri R, Karppinen J, et al. Lifestyle and metabolic
17. National Institute for Health and Care Excellence. London. factors in relation to shoulder pain and rotator cuff tendinitis: a
Low back pain and sciatica in over 16s: assessment and population-based study. BMC Musculoskeletal Disorders. 2010
management: NICE guideline 59. 2016. (cited 2020 Aug 30) Jul 20;11(1):165.
Available from: https://www.nice.org.uk/guidance/ng59
18. Pedersen BK, Saltin B. Exercise as medicine–evidence for Chapter 14: Supporting people to change
prescribing exercise as therapy in 26 different chronic diseases. their health behaviour
Scandinavian Journal of Medicine and Science in Sports. 2015 1. Michie S, Van Stralen MM, & West R. (2011). The behaviour change
Dec 1;25(S3):1-72. wheel: a new method for characterising and designing behaviour
change interventions. Implementation science, 6(1), 42.
19. Klein EE, Weil Jr L, Weil Sr LS, Fleischer AE. Body mass index
and achilles tendonitis: a 10-year retrospective analysis. Foot 2. Rollnick S, Mason P, Butler C. (1999) Health Behaviour Change:
and Ankle Specialist. 2013 Aug;6(4):276-82. A guide for practitioners. London: Churchill Livingstone.
20. Scott RT, Hyer CF, Granata A. The correlation of Achilles 3. Resnicow K, Diiorio C, Soet JE, Ernst D, Borrelli B, Hecht J.
tendinopathy and body mass index. Foot and Ankle Specialist. (2002). Motivational interviewing in health promotion: it sounds
2013 Aug;6(4):283-5. like something is changing. Health Psychology; 21:444-451.
21. Ellingson LD, Colbert LH, Cook DB. Physical activity is related 4. Rubak S, Sandback A, Lauritzen T, Chitensen B. (2005)
to pain sensitivity in healthy women. Medicine and Science in Motivational interviewing: a systemic review and meta-analysis.
Sports and Exercise. 2012 Jul;44(7):1401-6. British Journal of General Practitioners; 55(513):305-312.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 84 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
5. Rollnick S, Butler C, Kinnersley P, Gregor, J, Mash B. (2010) 7. Thompson DL, Rakow J, Perdue SM. (2004) Relationship
Motivational interviewing. British Medical Journal; 340:c1900. between accumulated walking and body composition in
middle-aged women. Med Sci Sports Exerc. 2004;36(5):911-4
6. Miller R, Rose G. (2009) Towards a theory of motivational
interviewing. American Psychological Association; 64:527-37 8. Tudor-Locke C, Sissson SB Lee SM et al (2005) Pedometer-
determined step count guidelines for classifying walking
7. Miller W, Rollnick S. (2012) Motivational Interviewing. Third intensity in a young ostensibly healthy population. Canadian
Edition. Motivational Interviewing: Helping people change. New Journal of Applied Physiology. 2005;3096):666-76
York: Guildford Press.
9. Wilde BE, Sidman CL, Corbin CB. (2001) A 10,000 step count
8. Olander EK, Fletcher H, Williams S, et al. (2013). What are as a physical activity target for sedentary women. Res Q Exerc
the most effective techniques in changing obese individuals’ Sport. 2001;72(4):411-4
physical activity self-efficacy and behaviour: a systematic
review and meta-analysis. International Journal of Behavioral 10. Tudor-Locke C, Bassett DR. (2004) How many steps/day are
Nutrition and Physical Activity, 10(1), 29. enough? Preliminary pedometer indices for public health.
Sports Medicine. 2004;34:1-8
9. Greaves CJ, Sheppar KE, Abraham C, Hardeman W,
Roden M, Evans PH & Schwarz P. (2011). Systematic review 11. Tudor-Locke C, Hatano Y, Pangrazi RP, Kang M. (2008)
of reviews of intervention components associated with Revisiting “How many steps are enough”. Medicine and Science
increased effectiveness in dietary and physical activity in Sports and Exercise. 2008,40:S537-543
interventions. BMC public health, 11(1), 119.
12. Tudor-Locke C, Ainsworth BE, Whitt MC et al. (2001) The
10. O’Donovan G, Blazevich AJ, Boreham C, et al. (2010) The ABC relationship between pedometer-determined ambulatory
of physical Activity for Health: a consensus statement from the activity and body composition variables. International Journal
British Association of Sport and Exercises Sciences. Journal of of Obesity. 2001;25:1571-8
Sport Sciences; 28:6:591 Appendix 1
13. National Institute for Health and Care Excellence.
11. National Institute for Health and Care Excellence London Behaviour change: individual approaches. 2014. (cited 2020
(2007). Behaviour change at population, community and Aug 30) Public health guideline PH49
individual levels: NICE public health guideline 6. (cited 2020 https://www.nice.org.uk/guidance/ph49/chapter/1-
Aug 30) https://www.nice.org.uk/guidance/ph6 Recommendations#recommendation-9-deliver-very-brief-
brief-extended-brief-and-high-intensity-behaviour-change
Chapter 15: Physical Activity and Starting to Get Active 14. Department of Health. (2007) Our NHS, our future: NHS next
1. The Scot-PASQ. (cited 2020 Aug) Available from: stage review – interim report. London: The Stationery Office.
http://www.healthscotland.scot/publications/physical-activity-
pathway-for-secondary-care 15. Royal College of General Practitioners. You and your GP.
Patient Information leaflet. London: RCGP, 2010. Historical Data
2. Skelton DA and Mavroedi, A. How do muscle and bone
strengthening and balance activities (MBSBA) vary across 16. BACR 2006 Phase IV Exercise Instructor Training Manual and
the life course, and are there particular ages where MBSBA ACSM (2009) Guidelines for Exercise Testing and Prescription
are most important? Journal of Frailty, Sarcopenia and Falls. (cited 2020 Aug 30) Available from:
2018;3(2):7484 http://www.bacpr.com/resources/BACPR_Protocol.pdf
3. Public Health England. Muscle and bone strengthening and 17. Thune I. Cancer Ch 19. Swedish National Institute of Public
balance activities for general health benefits in adults and Health. Physical Activity in the prevention and treatment of
older adults: Summary of a rapid evidence review for the UK disease. 2010. (cited 2020 19 Aug 15). Available from:
Chief Medical Officers’ update of physical activity guidelines. http://www.fyss.se/wp-content/uploads/2018/01/19.-Cancer.pdf
London; 2018
18. Smart NA, Williams AD, Levinger I, et al. Exercise & Sports
4. Tudor-Locke C, Sisson SB, Lee SM et al. (2006) Evaluation of Science Australia (ESSA) position statement on exercise and
quality of commercial pedometers. Canadian Journal of Public chronic kidney disease. Journal of Science and Medicine in
Health. 2006;97:S10-5 Sport. 2013 Sep 30;16(5):406-11.
5. Chan CB, Ryan DA, Tudor-Locke C. (2004) Health benefits of 19. Riddell MC, Gallen IW, Smart CE, et al. Exercise management
a pedometer-based physical activity intervention in sedentary in type 1 diabetes: a consensus statement. Lancet Diabetes
workers. Preventive Medicine. 2004;39 (6): 1215-22 Endocrinol. 2017 May;5(5):377-390
6. Le Masurier GC, Sidman CL, Corbin. (2003) Accumulating 20. Colberg SR, et al. Physical Activity/Exercise and Diabetes: a
10,000 steps: does this meet current physical activity Position Statement of the American Diabetes Association.
guidelines? Res Q Exerc Sport. 2003; 74(4): 389-94 Diabetes Care. 2016. 39, 2065-2079
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 85 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING
References
21. Pedersen BK, Saltin B. Evidence for prescribing exercise as Further resources:
therapy in chronic disease. Scandinavian Journal of Medicine
and Science in Sports. 2006 Feb 1;16(S1):3-63. These chapters are extracts from the Health Education in Wales
CPD module Motivate2Move on physical activity found at:
22. Ribom EL, Piehlm-Aulin K. Ch 38. Osteoporosis. Swedish https://gpcpd.heiw.wales/clinical/motivate-2-move/
National Institute of Public Health. Physical Activity in the where more bite size sections on other benefits of physical activity
prevention and treatment of disease. 2010. (cited 2019 can be found. There are also patient resources to signpost the
Oct 15). Available from: http://www.fyss.se/wp-content/ public to, links into yet more detailed information and other
uploads/2018/01/38.-Osteoporosis.pdf relevant organizations.
24. Meah VL, Davies GA, Davenport MH. Why can’t I exercise
during pregnancy? Time to revisit medical ‘absolute’ and
‘relative’ contraindications: systematic review of evidence of
harm and a call to action. Br J Sports Med 2020;54:1395-1404.
PHYSICAL ACTIVITY: A GUIDE FOR HEALTH PRACTITIONERS (V10) 86 THE BENEFITS OF PHYSICAL ACTIVITY ON OUR HEALTH AND WELLBEING