2023-64400-008 Bipolar
2023-64400-008 Bipolar
2023-64400-008 Bipolar
Disorders
James H. Kleiger
https://doi.org/10.1037/0000356-008
Psychological Assessment of Bipolar Spectrum Disorders, J. H. Kleiger and I. B. Weiner (Editors)
Copyright © 2023 by the American Psychological Association. All rights reserved.
107
108 James H. Kleiger
The Schedule for Affective Disorders and Schizophrenia (SADS; Endicott &
Spitzer, 1978) was constructed to assist with Axis I diagnostic decision making.
The psychometric properties have been established for both symptoms and
diagnoses (Andreasen et al., 1981; Rogers et al., 2001). Mania symptom ratings
achieved good reliability (interrater and test–retest) from 5 to 10 years with
young adults (Coryell et al., 1995; Rice et al., 1986). The SADS was also shown
to correlate significantly with other measures of mania (Secunda et al., 1985).
The SADS-C (Change Version) mania subscale is a five-item interview that
assesses the severity of current dimensions of mania (Spitzer & Endicott, 1977).
Rating Scales and Screening Assessment of Bipolar Spectrum Disorders 109
Spitzer and Endicott (1977) developed the SADS-C into an 11-item Mania
Rating Scale (MRS), which was found to have strong psychometric properties.
The Kiddie Schedule for Affective Disorders and Schizophrenia for School Aged
Children, Present and Lifetime Version (KSADS-PL) was developed (Kaufman
et al., 2000) for the Diagnostic and Statistical Manual of Mental Disorders (5th ed.;
DSM-5; American Psychiatric Association, 2013). Like the SADS, the KSADS-PL
provides a reliable and valid diagnostic assessment of DSM disorders. The MRS
(Axelson et al., 2003) is based on items from the WASH-U-KSADS (Geller et al.,
2001). The interviewer rates the presence of 15 symptoms of mania or hypo-
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mania over the past 2 months. Some symptoms, such as a need for sleep, racing
thoughts, hyperactivity, grandiosity, and increased energy are also rated if they
fluctuate with an expansive or irritable mood. It is important that raters can
clearly demarcate the beginning and end of manic and hypomanic episodes. The
rater also needs to establish whether multiple symptoms occurred at the same
time. If any items are judged to be present, the interviewer inquires into how the
child was behaving at the time.
Like the SCID and SADS, the KSADS-PL can be time-consuming to learn and
administer. Psychologists in general outpatient settings may not have the time to
conduct gold standard interview scales, not to mention the excessive demands
that lengthy interviews may place on children with limited tolerance for sitting
and focusing.
KSADS-PL materials are available for clinical use with permission from the
authors at the website of the University of Pittsburgh Center for Childhood
Bipolar Spectrum Services. The KSADS-PL is available online from the Kennedy
Krieger Institute (https://www.kennedykrieger.org/sites/default/files/library/
documents/faculty/ksads-dsm-5-screener.pdf). Focal assessment with the Manic
or Depression Rating Scales of the KSADS may also be downloaded from the
University of Pittsburgh website (https://www.pediatricbipolar.pitt.edu/resources/
instruments).
One of the oldest and most frequently used MRSs is the Young Mania Rating
Scale (YMRS), an 11-item clinician-rated instrument (Young et al., 1978).
Modeled on the Hamilton Depression Scale (Hamilton, 1960), the YMRS is
based on a 15- to 30-minute interview conducted by a trained clinician. The
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Mania Scale
Like the YMRS, the Mania Scale (MAS; Bech et al., 1979) is used in both clinical
and research settings. Also known as the Bech–Rafaelsen Scale, the MAS covers
the same dimensions of mania as the YMRS and has been shown to have
excellent psychometric properties. The MAS consists of 11 items assessing motor
activity, verbal activity, flight of thoughts, voice/noise level, hostility/destruc-
tiveness, mood (feelings of well-being), self-esteem, contact with others, sleep
changes, sexual interest, and work activities. Each item is rated on a 5-point scale
with 0 indicating normal mood and behavior and 4 indicating severe
impairment. The total score can be used to reflect the severity of mania as
mild (15–20), moderate (21–28), marked (29–32), severe (33–43), or extreme
(≥44). Behavioral anchors are provided for each rating. Ratings are made for
symptoms that occur over the past 3 days, based on a clinical interview with the
client which takes 15 to 30 minutes to complete.
Rating Scales and Screening Assessment of Bipolar Spectrum Disorders 111
Bipolarity Index
The Pediatric Behavior Rating Scale (PBRS; Marshall & Wilkerson, 2008) is a
commercially published parent- and teacher-rated scale for identifying early-
onset bipolar disorders in children aged 3 to 18. Norm-referenced scores are
computed for Symptom Scales and a Total Bipolar Index. A Validity Scale
(inconsistent responses) and Critical Items are also reported. Symptom scales
include Atypicality (psychotic symptoms), Grandiosity, Aggression, Irritability,
Hyperactivity, Inattention, Affective Disturbance, and Social Interactions. The
parent scale contains 102 items and the teacher scale has 95 items. T scores
above 70 reflect emotional dysregulation, and scores above 80 suggest the
presence of early-onset bipolar disorder. The manual contains information
on psychometric features. Validity studies mostly consist of correlations
with other screening measures like the Child Mania Rating Scale (CMRS),
Behavioral Assessment System for Children, and Clinical Assessment of
Behavior.
BPSS-P correlated with other scales measuring depressive and manic symp-
toms, its use in prospective studies has not been demonstrated.
SELF-REPORT SCALES
Whereas gold standard measures like the SCID, SADS, and KSADS-PL are
diagnostic in scope, self-report scales are screening instruments that, if positive,
suggest the need for a more comprehensive evaluation. Self-report scales
are appealing for clinicians or researchers looking for diagnostic support from
user-friendly, evidence-based instruments. Scales are grouped in terms of (a)
symptom-specific measures (mania, depression, and bipolar II disorder), (b)
biphasic symptoms of bipolar spectrum disorders, and (c) prodromal symptoms
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of bipolar disorders.
Mania-Specific Scales
Hypomania Checklist
The Hypomania Checklist (HCL-32) is a questionnaire consisting of 32 items
developed for identifying hypomanic features in patients presenting with a
depressive episode (Meyer et al., 2007). Angst et al. (2005) described HCL-32 as
a sensitive but less specific measure for distinguishing major depression from
bipolar disorders.
accuracy in differentiating youth with bipolar disorders from children with other
psychiatric disorders, including ADHD (Henry et al., 2008). The CMRS-P is in the
public domain and can be downloaded from https://brainandwellness.com/
accordian/upload_file/CMRS-P_followup.pdf.
Bipolar-II–Specific Scales
MoodCheck
MoodCheck is a self-report scale that combines questions from the BSDS with
the Bipolarity Index described previously (Phelps, 2014). Parts A and B are the
original items in the BSDS. Part C screens for a family of possible bipolar
spectrum conditions. Part D consists of 13 questions that form the basis of
the Bipolarity Index. MoodCheck is a quick and cost-effective way to screen for
bipolarity, including nonmanic and mixed features, in patients presenting with
depression. The instrument is simple to score and interpret. The MoodCheck
can be downloaded for free from https://psycheducation.org/blog/moodcheck-
bipolar-screening.
order in youth with ADHD (Biederman et al., 2009). As a result, they termed this
profile “the pediatric bipolar disorder phenotype” or CBCL-PBD. However, Diler
et al. (2009) found that the profile also predicted conduct disorders and
depression. Thus, the CBCL-PBD became regarded as an indicator of general
psychopathology, predicting the severity of the disorder and poor functioning.
A 19-item mania scale developed from CBCL (CBCL-MS; Papachristou et al.,
2013) was found to have acceptable psychometric properties. Internal consis-
tency was high, and the scale effectively differentiated young people with Type I
bipolar disorder (BD-I) from nonclinical controls. Young subjects with BD-I were
also found to score higher on the CBCL-MS than those subjects diagnosed with
anxiety (p .004) and major depression (p .002). However, high scores on the
CBCL-MS did not discriminate between BD-I and ADHD or oppositional defiant
disorder. Finally, a longitudinal study of youth in the Netherlands found that 11-
year-olds who had mild to higher levels of symptoms on the CBCL-MS were 2–5
times more prone to be diagnosed with bipolar disorders by the age of 19
(Papachristou et al., 2017).
Providing that they have good psychometric properties and are sensitive and
specific to the groups being studied, rating scales are easy-to-administer tools
that can save clinicians time. Scales with acceptable psychometric properties can
add evidence-based support for clinical inferences and also indicate the need to
delve more deeply into the nature and severity of symptoms.
Screening scales are helpful for clinicians in general practice for treatment
decision making, primarily as it relates to prescribing medication and tracking
symptoms to gauge change or response to treatment. Screening measures can
also be used productively in psychological assessment, provided that psycho-
diagnosticians remember that most such measures are what the name implies:
screening tools that help determine whether more in-depth assessment instru-
ments are indicated.
Rating Scales and Screening Assessment of Bipolar Spectrum Disorders 117
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