Key Questions in Congenital Cardiac Surgery

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Key Q � "'l CO"IG NITA C-ARC AC SURCE-1,(v'

Figure 7. Centrifugal pump mounted on the rotating


magnetic device, with the mandatory back-up device
adjacent for immediate transfer of the propeller.

1 0 What are the main factors affecting extracorporeal


c- ,.. g on Im
• The pump provides a blood flow rate (Umin) delivered at a given
amount of revolutions per minute (rpm).
• Factors that can affect the blood flow rate include:

a) preload and afterload;


b) size of the cannulae;
c) size of the cannulated vessels and compliance;
d) body surface area (BSA) of the patient;
e) haematocrit;
f) transmembrane gradient (which represents the pressure
gradient across the oxygenator).

• The pump generates a negative pressure on the patient's venous


side, which drives the flow rate, as it provides the inflow into the
propeller.
• Past the point of maximal inflow, the negative pressure in the venous
system causes the venous vessels or the right atrial wall to
temporarily collapse, potentially occluding blood inflow altogether.
• When the pressure in the venous side builds back up again, the
pump is able to flow again, which might generate a pulsing blood
flow and cavitation of the pump.
• The first intervention to avoid further cavitation is to reduce the pump
rpm and therefore the suction effect on the venous return.

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