64a957adee30870018a3998d - ## - Human Health and Diseases Handwritten Notes (Of Lecture 01)

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HUMAN HEALTH AND DISEASE

LECTURE 01

IMMUNITY 8

to Ability the host to the disease


of fight causing
organisms Ipathogens

Immunity is of two types i Innate Immunity

F Acquired Immunity

INNATE
Timmy ACQUIRED
Present by birth Inborn Immunity Gained during the
lifetime Adaptive
Immunity
Non specific Reacts in a a
Highly specific
similar way to all disease
causing agents

9 No memory i.e it doesnot o Has memory


remmember the encounter
with pathogen
from the
Previous time

8
INIT IMMUNITY
Non specific type of defence
Present at time birth
the
of
Provide
different types of barriers to the entry of
in our body
forgein agents
Inate immunity consist 4
types of barriers
of 8

is Physical Barrier
1st line of Defense
is Physiological Barrier

Ii Cellular Barrier
2nd line
of defense
I Cytokine Barrier

107 PHYSICAL BARRIER 8


main barrier which
a sky prevent entery of
micro organisms
b Mucus COATING 8
Of GI Gastrointestinal tract
Respiratory tract and Urogenital
tract
Prevent physical entry disease
of causing
agent

2 PHYSIOLOGICAL BARRIER 8
o
HCl in stomach

Lysozyme Antibacterials in tears saliva

Secretions
providing Immunity
o

3 CELLULAR BARRIER 8
o
Macrophages
1 Monocyte type of way
88888 EIbes
qq.iq

1 Neutrophils also called Phil Polymorphonuclear leucocyte

All
three types are phagocytic cells
D NK cells Natural Killer cells typeof lymphocytes
non cells
phagocytic
tumor cells
target

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