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Neurobion Injection Leaflet Size: WxH: 105mm x 146mm

Approved by :
Approved on : 10:00 27th April, 2015

Injections.
• Due to the high content of active ingredients to be used with caution in children
Tell your doctor before taking Neurobion Injections if you
• Have hereditary galactose or fructose intolerance
• Have Glucose-galactose malabsorption
• Have lactose intolerance
• Have sucrose intolerance.
Your doctor may adjust your dose accordingly as Neurobion contains lactose and sucrose.

Neurobion
®
®
Injection Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines,
(Vitamin B1 + B6 + B12) including medicines obtained without a prescription. In particular:
• medicines containing dopamine, levodopa (a drug to control Parkinson’s disease, a progressive
brain disorder)
• Phenytoin or phenobarbitone (drugs to control epilepsy)
Composition: • Sulfasalazine (drug to control pain in arthritis)
Neurobion Injection: Each 3 ml contains: • Warfarin, heparin or other such drugs that are blood thinners.
Vitamin B1 (Thiamine Hydrochloride), USP........100 mg
Vitamin B6 (Pyridoxine Hydrochloride), USP .... 100 mg Pregnancy and breastfeeding
Vitamin B12 (Cyanocobalamin), USP............ 1000 mcg No risks have become known associated with the use of Neurobion during pregnancy at the
recommended dosage. Vitamins B1, B6 and B12 are secreted into human breast milk, but risks of
Read all of this leaflet carefully before you start taking this medicine because it contains overdose for the infant are not known. In individual cases, high doses of vitamin B6, i.e. > 600 mg
important information for you. daily, may inhibit the production of breast milk
• Keep this leaflet. You may need to read it again. Driving and using machines
• If you have further questions, ask your doctor or your pharmacist. This medicine should not affect your ability to drive or use machines.
• This medicine has been prescribed for you only. Do not pass it onto others. It may harm them,
even if their signs of illness are the same as yours. What are the adverse effects of Neurobion Injection?
• If you get any side effects, talk to your doctor or pharmacist. This includes any possible side Like all medicines, Neurobion Injections can cause side effects, although not everybody gets them.
effects not listed in this leaflet. Contact your doctor at once if the following effects happen:
• Allergic reactions, including rash, itching.
What is in this leaflet? • Hear burn, belching, abdominal pain with or without cramps, loss of appetite, diarrhea, vomiting
• What is Neurobion Injection? and nausea.
• What are the indications for Neurobion Injection? • Liver abnormalities or abnormal liver function tests
• What should be the dose of Neurobion Injection? • Acne or similar skin reactions.
• What are the contraindications of Neurobion Injection? • Redness of face or other areas of the skin, faintness, dizziness.
• What are the adverse effects of Neurobion Injection? • Muscle weakness, painful muscular cramps, muscle loss, changes in skin, hair and nails could be
• Other information for Neurobion Injection? signs of peripheral sensory neuropathies
• Stone formation with prolonged heavy doses of folic acid have been reported.
What is Neurobion Injection? • Avoid using a combination of vitamin B12, folate, and vitamin B6 after receiving a coronary stent.
Neurobion Injection is a combination of Vitamin B1, B6 and B12. Vitamin B1 or Thiamin is required for This combination may increase the risk of blood vessel narrowing.
energy metabolism and important to nerve function. Vitamin B6 or Pyridoxine is needed for protein If you notice any other side effects not listed, please tell your doctor or pharmacist.
metabolism; helps make red blood cells. B12 or Cobalamin, also helps to prevent a certain type of
anemia. Other important information for Neurobion Injection?
What are the indications for Neurobion Injection? Presentation
Neurobion Injections are indicated for the treatment of herpes zoster or shingles or zona a disease Neurobion Injection: Available pack of 25 x 3 ml ampoules
characterized by painful skin rash with blisters.
Neurological systemic diseases due to a severe lack in vitamin B1, B6 and B12, when oral therapy is Storage
insufficient. Store below 30 ºC.
Protect from light and heat.
What should be the dose of Neurobion Injection? Keep all medicines out of the reach of children.
In severe cases one ampoule daily by deep intramuscular through slow intragluteal, injection is the
recommended dose or as prescribed by your physician. This dosage is to be continued until the
disappearance of the acute symptoms. In milder cases and for follow-up treatment one ampoule is to
be given 2-3 times weekly. Because of the possibility of sensitization against vitamin B1, intravenous Manufactured by:
injection of Neurobion should be made cautiously and slowly while observing the patient for possible Martin Dow Marker Ltd
allergic reaction. Combination with glucose solution is often beneficial in intravenous injection. 7, Jail Road, Quetta, Pakistan,
under licence of Merck KGaA,
What are the contraindications of Neurobion Injection? Darmstadt, Germany.
Do not take Neurobion Injections 13002752
• if you are allergic (hypersensitive) to Neurobion or any of the other ingredients of Neurobion