Introduction
Introduction
Introduction
Lecture 1
INTRODUCTION TO
PATHOPHYSIOLOGY
2020.
Objectives
In this lecture we will be focus on :
MODELING
❖ is the main pathophysiology method
❖ is the main method of modeling diseases,
pathological processes, states and reactions
General nosology
Nosology /nosos = disease; logos = science/
Systematically describes the specific type of disease and this is
the base for creation classification system of diseases
Criteria of health:
1. State of optimal wellness and absent of complaints for health.
2. Objective examination with diagnostic evaluation methods which
reveal absence of signs and symptoms of disease.
3. Absence of signs and symptoms after examination with different
laboratory tests of functional reserve of organs and physiologic
systems.
• Norm :
• is the state of optimum activity of an organism in
specific conditions of its existence.
• is statistic standard ranges resulting from mass
examination of population.
Normal standard derivations are connecting with
age and gender. Homeostatic and points vary widely
among individuals. Clinical reference points, or
norms, for measurable physiologic parameters are
statistically derived from group means but must
often be adjusted on the basis of age, gender, height,
or weight.
Disease (literally, “lack of ease”) – process
disrupting physiologic function and resulting in
characteristics signs and symptoms.
Disease
• is an objective state that is demonstrated by an
observable structural or functional abnormality
• is characterized by decreased physical and social
adaptation
• is an abnormal state in which part or all of the
body is not properly adjusted or is nor capable of
carrying on all its required functions
Disease – loss of homeostasis, or when physical
or mental capacities cannot be fully utilized
(interuption, cessation or disorder in the
function of an organ or system).