Thymovac - Product Introduction
Thymovac - Product Introduction
Thymovac - Product Introduction
PM-VN-22-0314
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VACCINATION AGAINST
CHICKEN ANEMIA VIRUS
• Current vaccine strategies are based on the prevention of vertical and horizontal
transmission of CAV to very young chicks by immunization of breeders.
• Effective vaccination against CAV decreases the risk of reduced performance and health of
chicken progenies
• For passive protection conferred to the progeny against clinical signs and lesions of CAV.
• The protection of the progeny is ensured for up to 43 weeks after vaccination, and chicks are
protected at one day old
• Administration in breeders from 8 weeks of age onwards, but no later than 6 weeks before
the onset of lay
» Higher & more homogeneous humoral response than other CAV vaccines
• High and homogeneous CAV antibody titers are needed throughout the entire breeder’s
production life cycle - Higher level of maternal immunity than other CAV vaccines
• AviPro® Thymovac induces higher and more homogeneous antibody - Easier administration
than injectable CAV vaccines response in breeder hens
Comparative study of three different CAV vaccines in Thailand. Niwat Chansiripornchai, Avian Health
Research Unit, Faculty of Veterinary Science, Chulalongkorn University, Thailand. WVPAC 2013 REF-09197
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AVIPRO THYMOVAC Live-attenuated, freeze-dried vaccine
Comparative study of three different CAV vaccines in Thailand. Niwat Chansiripornchai, Avian Health Research Unit,
Faculty of Veterinary Science, Chulalongkorn University, Thailand. WVPAC 2013 REF-09197
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AVIPRO THYMOVAC
High & long lasting humoral response
LONG-LASTING HUMORAL RESPONSE
CHICKEN ANEMIA VIRUS (CAV) SEROLOGY PROFILE OF BREEDERS AND THEIR PROGENY- REF-01837
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AVIPRO THYMOVAC
High & more homogenous humoral response
9 wks before vaccination
Uniform response
Uniform response
CHICKEN ANEMIA VIRUS (CAV) SEROLOGY PROFILE OF BREEDERS AND THEIR PROGENY- REF-01837
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AVIPRO THYMOVAC
High level of maternal antibody
CAV maternal antibody titers
CHICKEN ANEMIA VIRUS (CAV) SEROLOGY PROFILE OF BREEDERS AND THEIR PROGENY- REF-01837
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AVIPRO THYMOVAC
High level of maternal antibody
100% 100% 100%
» The offspring from parent stock vaccinated
with AviPro® Thymovac and challenged with
CAV did not show any clinical signs or lesions
and presented a normal hematocrit value
35%
indicating complete and effective protection
24% against CAV.
0% 0% 0%
» The high level of maternal antibody titers
BONE
MARROW
THYMUS
LESIONS
CLINICAL
SYMPTOMS
HEMATOCRIT
provides an effective protection against CAV.9
LESIONS
CHICKEN ANEMIA VIRUS (CAV) SEROLOGY PROFILE OF BREEDERS AND THEIR PROGENY- REF-01837
© 2021 Elanco or its affiliates
PM-VN-22-0314 01/2022/XNQC-TY
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AVIPRO THYMOVAC
High level of maternal antibody
Lesions at 2 weeks after CAV + IBDV challenge
» The progeny from birds immunized with
3 3 AviPro® Thymovac and challenged with CAV
and IBDV showed slight lesions in the thymus
and bone marrow compared to the severe
lesions in the control group.
1.1
0.8 » Lower impact of CAV + IBDV co-infection is
observed due to the high level of maternal
antibody titers.10
BONE THYMUS
MARROW LESIONS
LESIONS
CHICKEN ANEMIA VIRUS (CAV) SEROLOGY PROFILE OF BREEDERS AND THEIR PROGENY- REF-01837
© 2021 Elanco or its affiliates
PM-VN-22-0314 01/2022/XNQC-TY
®
AVIPRO THYMOVAC
Easier administration
The use of vaccination in poultry production. S. Marangon & L. Busani. Rev. sci. tech. Off. int. Epiz., 2006, 26 (1), 265-274.
Drinking Water Vaccination: Easy and Effective. Technical Bulletin. Bernardi E, and Johnson S. 2011 (1931).
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AVIPRO THYMOVAC
Easier administration
Injectable CAV AviPro® Thymovac
vaccines DRINKING
PARENTERAL WATER
The use of vaccination in poultry production. S. Marangon & L. Busani. Rev. sci. tech. Off. int. Epiz., 2006, 26 (1), 265-274.
Drinking Water Vaccination: Easy and Effective. Technical Bulletin. Bernardi E, and Johnson S. 2011 (1931).
© 2021 Elanco or its affiliates PM-VN-21-0330
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AVIPRO THYMOVAC
Take Away
• Higher & more homogeneous humoral response than other CAV vaccines
FEELING
THE POWER
A v iP r o , E la nc o a nd t he d ia g o na l b a r a r e t r a d e m a r k s o f E la nc o
o r it s a f f ilia t e s . © 2 0 2 0 E la nc o . PM-GLB-MAR-20-0636
AviPro® Thymovac: Live vaccine (freeze-dried) for poultry against Chicken Infectious Anaemia. For oral administration via the drinking
water. Composition: 1 dose contains min. 104.5 TCID50 CIA virus, strain Cux-1. Indications: Active immunisation of breeder pullets and
passive immunisation of their progeny against Chicken Infectious Anaemia. Contraindications: Do not vaccinate clinically ill or
weakened birds. Do not vaccinate before 8 weeks of age and not later than 6 weeks before the point of lay. Side effects: Not known.
Interactions with other products: Not known. Directions for use: Administer 1 dose per bird. Withdrawal: 0 days. For veterinary use only.
Storage: Keep at + 5°C ± 3°C. Do not freeze. Protect from sunlight.
© 2021 Elanco or its affiliates