M - W P F E EM C W B T: Etamaterial Inspired Earable AD OR Nhancing Oupling ITH Iological Issues
M - W P F E EM C W B T: Etamaterial Inspired Earable AD OR Nhancing Oupling ITH Iological Issues
M - W P F E EM C W B T: Etamaterial Inspired Earable AD OR Nhancing Oupling ITH Iological Issues
Overview of the functionality of the proposed metamaterial-inspired wearable pad for enhancing the EM
coupling with biological tissues at 2.4 GHz.
Take-Home Messages
This paper proposes a totally passive, wearable, thin pad, comprising metallic structures embedded in a
dielectric material for effectively couplingVisual Summary
EM radiation to a biological tissue.
The improvement in transmission to a small, implantedx antenna
Max 4 inch 6 inch was measured to be more than 4 dB in the 2.4-
2.5 GHz range.
The proposed pad can be used as an auxiliary tool in various biomedical applications, from hyperthermia to
implant technology for enhancing communication and/or wireless charging.
A thin, flexible and mechanically robust pad was developed for clinical and every-day biomedical applications.
METAMATERIAL-INSPIRED WEARABLE PAD FOR
ENHANCING EM COUPLING WITH BIOLOGICAL
TISSUES
Maria Koutsoupidou*, Dimitrios C. Tzarouchis*, Member, IEEE, Dionysios Rompolas,
Ioannis Sotiriou, George Palikaras, and Panagiotis Kosmas, Senior Member, IEEE
Abstract Wearable, implantable, and ingestible antennas are continuously evolving in biomedical applications, as they are crucial
components in devices used for monitoring and controlling physiological parameters. This work presents an experimentally
validated wearable pad which can improve transmission of electromagnetic waves into the human body. This metamaterial-inspired
matching pad, which is based on small metallic loops encased in a thin dielectric layer, is mechanically stable, flexible, and passive.
As such, the pad can serve as a coupling medium for microwave medical systems and implantable device communication.
Operating in the 2.4-2.5 GHz range, the pad demonstrates significant improvement in signal penetration levels (and, hence, depth)
into a biological tissue. The study presents design methodology, simulation studies, in-lab development, and experimental
characterization of this pad, which can offer a practical solution for enhanced communication and functionality in various medical
diagnostic systems.
Keywords —antenna measurements, dielectric materials, electromagnetic coupling, implantable biomedical devices, metamaterials,
phantoms
Β IOMEDICAL applications covering imaging, sensing, a) significant reflection at the air-skin interface, and b) rapid
and communication across RF to mm-waves necessitate signal attenuation within the tissue due to its high losses,
the transmission and reception of electromagnetic (EM) resulting in limited penetration depths relative to the
waves to and from human tissues. Typically, one or more application frequency. This limitation is particularly
antennas are employed in close proximity to or within the pronounced in the 2.40-2.50 GHz range (2.4 GHz ISM
human body. Recent progress in the field of biomedical band), which is the frequency band allocated for various
engineering includes the development of systems of communication protocols like WLAN and Bluetooth [8], [9].
wearable, implantable, and ingestible antennas for Signal attenuation within tissues presents an inherent
monitoring and/or controlling various physiological challenge, and potential solutions include shifting to lower
parameters [1], [2], as well as managing or treating frequencies, targeting shallow tissue layers, or increasing the
symptoms [3], [4], [5]. The seamless functioning of these overall radiated power. However, these options may not
devices, especially the long-term operation of implantable
ones within the human body, relies heavily on their capacity
to establish communication with an external base. This
communication is essential for tasks such as data sharing,
control, and wireless charging. Similarly, the efficiency of
other microwave diagnostic and therapeutic applications,
including imaging [6] and hyperthermia [7], depends on the
enhanced coupling of the EM radiation with the tissue and
the localization toward a specific site or target. The impact
of these applications on patients’ well-being, quality of life,
and healthcare systems is very significant.
The widespread clinical adoption of innovative EM
Fig. 1. Concept image of the proposed wearable pad for enhancing implant
diagnostic and therapeutic tools, particularly implantable technology and theranostic systems.
technology, requires effective coupling with biological
1
The paper was submitted for review on April 09, 2024. D. C. Tzarouchis is now with the Broadband systems & wireless
All authors were with Meta Materials Europe S.A., Ap, Pavlou 10a, Technologies Department, Intracom Telecom S.A., 19002, Peania, Greece.
Marousi, T.K. 15123, Athens, Greece. * These authors contributed equally to this work.
M. Koutsoupidou is now with Hellenic Military Academy, Evelpidon
Avenue,Vari, Greece. (e-mail: [email protected])
> REPLACE THIS LINE WITH YOUR PAPER IDENTIFICATION NUMBER (DOUBLE-CLICK HERE TO EDIT) < 3
Fig. 4. (a) Field distribution of the electric field excited by a dipole antenna
located at 130 mm above a three-layer tissue comprising (from top to bottom)
skin, fat, and muscle, with the pad lying on the tissue surface. (b) Power
density calculated at depths of 10 mm, 20 mm, and 30 mm below the tissue
surface with (solid line) and without (dashed line) the pad in the 2-3 GHz
range. (c) Improvement in dB of the power density with the pad for different
depths in the tissue at 2.45 GHz.
properties. The mixture was poured in the mold and placed Depth of implanted 2.4 GHz 2.45 GHz 2.5 GHz
in the fridge. antenna
The dielectric properties of the developed phantoms 8 mm 1.8 dB 4.1 dB 5.4 dB
measured at 2.45 GHz with the DAK12 probe (SPEAG®)
15 mm 2.0 dB 3.9 dB 4.4 dB
and the results vs the model values are shown in Table I.
Initially, the socket for 8 mm was used and each gel mixture
was poured following solidification of the previous one. The been significantly detuned (Fig. 8b). Additionally, the
final experimental setup is shown in Fig. 7c: the metallic transmission enhancement because of the pad is higher than
loop-based pad lies on the three-layer phantom and the 2 dB from 2.4 GHz to 2.6 GHz, peaking at 2.5 GHz. We get
external antenna is attached to the top cover of the box, to similar results for the 15 mm depth, where the pad improved
ensure that it is stable and located at specific, controlled the |S21| at 2.45 GHz by 3.9 dB (Fig. 8c). The immersed
distances during the experiment. The antennas’ S-parameters dipole is more stable at this depth because of its increased
with and without the pad were measured using an distance from the pad’s inductive loops. Generally, the
R&S®ZNBT VNA. To replicate the experiment with the transmission enhancement matches well the simulation
antenna positioned inside the 15 mm socket within the tissue, results of Section II.B. A summary of the measured
new phantoms were fabricated after destroying the previous improvement in S21 scattering at specific frequencies in the
ones, and the experiment was conducted again. 2.4-2.5 GHz frequency range is shown in Table II.
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