Republic of the Philippines

Department of Education
Region VI – Western Visayas
SCHOOLS DIVISION OF ROXAS CITY
District I - Cluster II
INZO ARNALDO VILLAGE INTEGRATED SCHOOL

Name: _____________________________________ Section: ______________________Score: ___________

Directions: Read each questions carefully. Encircle the letter of the correct answer.
1) Which level of organization is the basic unit of life?

a) Cell c) Organ
b) Tissue d) System
2) The term "omnis cellula e cellula" is associated with:

a) Anton van Leeuwenhoek c) Rudolf Virchow

b) Robert Hooke d) Matthias Schleiden
3) Which statement best explains the cell theory?

a) Cells are the basic unit of life, all living things c) Cells are only found in animals, not in plants.
are composed of cells, and cells arise from pre- d) Cells are static structures that do not change
existing cells. over time.
b) Cells are the building blocks of tissues, and
all cells contain a nucleus.
4) Which of the following is not one of the principles of the cell theory?
a) All living organisms are composed of cells. c) Cells can arise spontaneously from non-living
matter.
b) The cell is the basic unit of structure and
d) Cells arise only from pre-existing cells.
organization in organisms.
5) Which organelle is responsible for the synthesis of proteins within the cell?
a) Golgi apparatus c) Mitochondria
b) Endoplasmic reticulum d) Ribosomes
6) What is the main job of the rough endoplasmic reticulum (ER) in cells?
a) Making fats c) Cleaning toxins
b) Making and changing proteins d) Storing calcium
7) Which organelle is involved in energy production through aerobic respiration?
a) Nucleus c) Chloroplast
b) Golgi apparatus d) Mitochondria
8) Which organelle contains enzymes responsible for breaking down cellular waste and recycling cellular
components?
a) Nucleus c) Ribosome
b) Golgi apparatus d) Lysosomes
9) What is a defining characteristic of prokaryotic cells?
a) They have a nucleus c) They have membrane-bound organelles
b) They lack a membrane-bound nucleus d) They are only found in multi cellular organisms
10) Describe the structure of the nucleus in eukaryotic cells and explain its function.
a) It contains DNA and is the site of protein c) It is the powerhouse of the cell, generating
synthesis. ATP for cellular activities.
b) It is a double membrane-bound organelle that d) It stores and modifies proteins before they are
houses the cell's genetic material. secreted from the cell.
11) Which of the following organisms are typically prokaryotic?
a) Bacteria c) Fungi
b) Plants d) Animals
12) What organelle is present in eukaryotic cells but absent in prokaryotic cells?
a) Golgi apparatus c) Mitochondria
b) Ribosome d) Nucleus
13) Which of the following is a feature of prokaryotic cells?
a) Presence of membrane-bound organelles c) Lack of a plasma membrane
b) Linear chromosomes d) Circular DNA
14) What type of tissue covers the surfaces of the body, lines organs, and forms glands in animals?
a) Connective tissue c) Epithelial tissue
b) Muscle tissue d) Nervous tissue
15) Which of the following is a characteristic of plant tissues but not animal tissues?
a) Presence of chloroplasts c) Ability to contract and relax
b) Ability to conduct electrical impulses d) Presence of blood vessels
16) Cartilage is an example of which type of tissue?
a) Epithelial tissue c) Muscle tissue
b) Connective tissue d) Nervous tissue
17) An animal tissue is responsible for generating force and movement?
a) Connective tissue c) Epithelial tissue
b) Muscle tissue d) Nervous tissue
18) Meristematic tissue in plants is responsible for:
a) Storing nutrients c) Growth and development
b) Providing mechanical support d) Conducting water and nutrients
19) Which of the following is NOT an example of muscular tissue?
a) Skeletal tissue c) Cardiac tissue
b) Smooth tissue d) Nervous tissue
20) Which of the following cell modifications is most likely to enhance nutrient absorption in cells lining the small
intestine?
a) Decreased surface area-to-volume ratio c) Microvilli on the cell surface
b) Presence of cilia d) Thickened cell membrane

21) Which of the following statements best reflects the relationship between villi and microvilli?
a) Villi are extensions of microvilli. c) Both a & b
b) Microvilli are extensions of villi. d) None of the above

22) How do cilia and flagella differ in their functions?

a) Cilia are primarily involved in cell c) Both cilia and flagella are exclusively involved
movement, while flagella are mainly involved in in propulsion of the cell.
moving fluids past the cell. d) Cilia are specialized for sensory functions,
b) Flagella are shorter and more numerous while flagella are involved in maintaining cell
compared to cilia, aiding in cellular locomotion. shape.
23) There is a presence of connexon that allow direct exchange of chemicals between the cytoplasm of two cells.
a) Gap Junction c) Tight Junction
b) Adhering Junction d) All of the above

24) What are the main phases of the cell cycle?

a) Interphase and Mitosis c) G1, S, G2, and M
b) Prophase, Metaphase, Anaphase, and d) Anaphase, Telophase, Cytokinesis, and Interphase
Telophase

25) Which of the following accurately describes the function of the G1 checkpoint in the cell cycle?
a) It ensures that DNA replication is complete c) It assesses DNA integrity and repairs damaged DNA
before the cell enters mitosis. before progression to S phase.
b) It monitors cell size and nutrient availability d) It prevents premature entry into mitosis by verifying
before committing to DNA synthesis. proper spindle assembly.
26) During which phase of the cell cycle does DNA replication occur?
a) G1 phase c) G2 phase
b) S phase d) M phase

27) What distinguishes the G2 phase from the G1 phase of the cell cycle?
a) G2 phase involves DNA replication, while G1 c) G2 phase is characterized by further cell growth and
phase involves cell growth and preparation for preparation for mitosis, whereas G1 phase primarily
division. involves intense cellular activity and protein synthesis.
b) G2 phase follows DNA synthesis (S phase) and d) G2 phase is regulated by the R-point checkpoint,
precedes mitosis, whereas G1 phase follows while G1 phase is regulated by the spindle checkpoint
mitosis.

28) What is the primary purpose of mitosis?

a) Production of gametes c) Introduction of genetic diversity
b) Growth and repair of somatic cells d) Formation of spores

29) During which stage of mitosis or meiosis does crossing over occur?
a) Prophase I of meiosis c) Anaphase II of meiosis
b) Metaphase of mitosis d) Telophase of mitosis

30) How many daughter cells are produced at the end of mitosis?
a) Two c) One
b) Four d) Eight

31) Which of the following statements best describes the main difference between anaphase of mitosis and anaphase I
of meiosis?
a) In anaphase of mitosis, sister chromatids
separate, while in anaphase I of meiosis,
homologous chromosomes separate. c) Anaphase of mitosis and anaphase I of meiosis
b) In anaphase of mitosis, homologous involve the same processes but occur at different times.
chromosomes separate, while in anaphase I of d) Anaphase I of meiosis involved
meiosis, sister chromatids separate.

32) What is the primary significance of mitosis in multi cellular organisms?

a) To produce gametes for sexual reproduction. c) To repair damaged tissues and replace dead cells.
b) To generate genetic diversity. d) To reduce chromosome number by half
 33) Explain the importance of mitosis in maintaining chromosome stability and genetic integrity.
a) Describe how errors during mitosis can lead to c) Analyze how mitosis contributes to the development
genetic mutations and diseases. and growth of organisms through cell proliferation.
b) Discuss the role of mitotic checkpoints in
d) Evaluate the impact of environmental factors on
preventing aberrant cell division and ensuring
mitotic activity and cellular homeostasis.
accurate chromosome segregation.

34) What is the significance of meiosis in sexual reproduction?

a) To produce identical daughter cells for growth c) To maintain chromosome number and prevent
and tissue repair. polyploidy.
b) To generate genetic variation among offspring. d) To facilitate DNA replication and cell division in
germ cells.
35) Discuss the evolutionary advantage of sexual reproduction over asexual reproduction, highlighting the role of
meiosis.
a) Compare and contrast the genetic diversity c) Explain the significance of genetic recombination and
generated by sexual and asexual reproduction. independent assortment during meiosis in generating
b) Evaluate how meiosis contributes to adaptive offspring with unique genetic combinations.
evolution and species survival in changing d) Analyze the trade-offs between reproductive
environments. strategies in terms of energy expenditure and
reproductive success.
36) Characterized by uncontrolled cell growth and division, leading to the formation of malignant tumors. It often
results from mutations in tumor suppressor genes or oncogenes.

a) Alzheimer's disease c) Diabetes mellitus

b) Parkinson's disease d) Cancer

37) Which disorder is caused by an abnormal number of chromosomes due to errors during cell division, particularly
during meiosis?

a) Cystic fibrosis c) Sickle cell anemia

b) Down syndrome d) Hemophilia

38) Which disorder results from mutations in the CFTR gene, leading to the production of thick, sticky mucus that
clogs the airways and digestive system?

a) Cystic fibrosis c) Sickle cell anemia

b) Down syndrome d) Hemophilia

39) This disorder is characterized by the abnormal folding and accumulation of misfolded proteins in the brain, leading
to cognitive decline and memory loss.
c) Huntington's disease
a) Alzheimer's disease d) Multiple sclerosis (MS)
b) Parkinson's disease
40) Which structural component of the cell membrane plays a crucial role in maintaining its fluidity and flexibility,
allowing cells to adapt to changes in their environment?
a) Cholesterol c) Glycoproteins
b) Phospholipids d) Integral proteins
41) What is the primary structural component of the cell membrane?
a) Proteins c) Lipids
b) Carbohydrates d) Nucleic acids
42) Which type of membrane protein spans the entire lipid bilayer and plays a key role in transport and cell
recognition?
a) Integral proteins c) Glycoproteins
b) Peripheral proteins d) Cholesterol

43) How does the presence of cholesterol in the cell membrane contribute to its function?
a) By facilitating cell-cell recognition c) By acting as enzymes for intracellular reactions
b) By enhancing membrane fluidity and stability d) By providing mechanical support to the cell

44) Which of the following statements is most accurate?

a) A higher concentration of peripheral proteins c) Variations in membrane protein composition can
enhances membrane transport. influence cell adhesion and migration.
b) Integral membrane proteins are less essential d) The absence of cholesterol in the membrane increases
for cell signaling compared to peripheral proteins. membrane permeability.

45) If you were to design a model of the cell membrane to illustrate its functions, which combination of structural
components would you include to best represent its diverse roles?
a) Integral proteins for transport, cholesterol for c) Peripheral proteins for cell adhesion, glycolipids for
stability, and phospholipids for fluidity communication, and cholesterol for flexibility
b) Glycoproteins for recognition, phospholipids d) Cholesterol for transport, glycoproteins for stability,
for barrier formation, and cholesterol for signaling and integral proteins for recognition

46) Requires specific carrier proteins to facilitate movement across the cell membrane?
a) Diffusion c) Facilitated diffusion
b) Osmosis d) Active transport

47) Which of the following describes osmosis?

a) Movement of water from high to low solute c) Movement of water against its concentration gradient
concentration d) Movement of solute facilitated by carrier proteins
b) Movement of solute from high to low
concentration

48) The following transport mechanism does not require energy input?
a) Diffusion c) Passive Transport
b) Osmosis d) Active transport

49) This process involves the fusion of vesicles with the cell membrane to release substances outside the cell?
a) Exocytosis c) Phagocytosis
b) Endocytosis d) Pinocytosis

50) In which process do cells engulf external substances by forming vesicles from the cell membrane?
a) Exocytosis c) Phagocytosis
b) Endocytosis d) Pinocytosis