Anemias - XLSX - Sheet1

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transferrin serum

Name reticulocytes MCV Cassification Other symptoms serum Fe TIBC


saturation ferratin

hereditary
↑ Normal hemolytic ↑ unconjugated bilirubin, ↑ LDH, ↓ haptoglobin
spherocytosis

hereditary
↑ Normal hemolytic ↑ unconjugated bilirubin, ↑ LDH, ↓ haptoglobin
elliptocytosis

G6PDD ↑ Normal hemolytic ↑ unconjugated bilirubin, ↑ LDH, ↓ haptoglobin

pyruvate
kinase ↑ Normal hemolytic ↑ unconjugated bilirubin, ↑ LDH, ↓ haptoglobin
deficiency

SCD ↑ Normal hemolytic ↑ unconjugated bilirubin, ↑ LDH, ↓ haptoglobin

paroxysmal
nocturnal
↑ Normal hemolytic ↑ unconjugated bilirubin, ↑ LDH, ↓ haptoglobin
hemoglobinur
ia

Bone
aplastic
↓ Normal marrow pancytopenia with hypocellular bone marrow
anemia
failure

Bone
Fanconi
↓ Normal marrow café-au-lait spots, short stature
anemia
failure
Bone
dyskarytosis
↓ Normal marrow dystrophic nails
congenita
failure

anemia of Bone
chronic ↓ Normal marrow liver disease, renal disease, or chronic inflammation ↓ ↓ low/normal normal/high
disease failure
transferrin serum
Name reticulocytes MCV Cassification Other symptoms serum Fe TIBC
saturation ferratin

Iron-deficient
↓ ↓ deficiency glossitis, angular stomatitis, koilonychia, pica, RLS ↓ ↑ ↓ ↓
anemia

↑ EPO, iron overload, hepatosplenomegaly, skeletal


Thalassemia-β ↓ ↓ hemolytic ↑ normal ↑ ↑
deformities

Thalassemia-α ↓ ↓ hemolytic severity increases with number of mutant chains inherited

B12- possible pancytopenia, glossitis, peripheral neuropathy,


↓ ↑ deficiency
deficiency spastic ataxia

Pernicious auto- atrophic gastitis resulting in loss of parietal cells (and thus
↓ ↑
anemia immune IF)

Folate
↓ ↑ deficiency possible ↓ WBCs and platelets; neural tube defects in fetus
deficiency

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