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    Assignment no 1 mb502

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    Mariyam Termezi
    molecular biology assignment solution

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    Assignment no 1 mb502

    Uploaded by

    Mariyam Termezi
    2 views2 pages
    molecular biology assignment solution

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    © © All Rights Reserved

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    DOCX, PDF, TXT or read online from Scribd

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    molecular biology assignment solution

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    2 views2 pages

    Assignment no 1 mb502

    Uploaded by

    Mariyam Termezi
    molecular biology assignment solution

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 2

    Assignment no 1

    MB502(Molecular Biology)
    Student ID: BC220415063
    Name: Mariyam Muneer

    Question No. 1
    A. What do you know about the work of Franklin and Wilkins?
    Answer:
    Rosalind Franklin and Maurice Wilkins were two British biologists. They played a crucial role in
    the understanding of DNA’s structure. They used X-ray diffraction analysis technique to examine
    the structure of DNA. Franklin was X-ray crystallographer and chemist and provided significant
    information on the double helix structure of DNA and its density. Her work produced high-
    quality X-ray images of DNA fibers, including the famous "Photograph 51," which exposed the
    helical pattern of DNA. This image was crucial in to analyze the DNA’s structure.
    Maurice Wilkins was a molecular biologist. He also worked at King's College and used X-ray
    diffraction to study the structure of DNA. His work was based mainly on the physical properties
    of DNA. Rosalind Franklin and Maurice Wilkins work was used by James Watson and Fransis
    Crick.

    B. How did it help Watson and Crick to propose the present model of DNA?
    Answer: Franklin's X-ray diffraction images specially Photograph 51 gave significant
    information that Watson and Crick used to determine the structure of DNA. The image showed
    1.A distinctive X-shaped pattern, indicating a helical structure
    2.Provided essential information such as the diameter of the DNA molecule
    3.The spacing between the nucleotides, and their orientation relative to each other.
    This data helped Watson and Crick build their double helix model, consisting of two
    complementary strands of nucleotides that twist together in a helical structure. They were
    composed of sugar and phosphate molecules making up the backbone and nitrogenous bases
    pairing with each other in a complementary way.
    In conclusion, the contributions of Franklin and Wilkins were crucial to this discovery and
    provided the critical data that Watson and Crick used to develop their groundbreaking model,
    which has had a profound impact on our understanding of genetics and molecular biology,
    leaving a lasting legacy in the field and inspiring new generations of researchers and scientists.

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