Calcifying Epithelial Odontogenic Cyst
Calcifying Epithelial Odontogenic Cyst
Calcifying Epithelial Odontogenic Cyst
(Seema Charantimath, Alka Kale Journal of Oral and Maxillofacial Pathology vol.8,issue 1,Jan-Jun 2004)
INTRODUCTION
Calcifying epithelial odontogenic cyst is a unique
odontogenic lesion. Gorlin and coworkers 1962 Lesion unusual some features of a cyst and also of a solid neoplasm.
CASE REPORT
16 yr old patient
region, extending from 22 to 24 patient was unaware. Swelling 1cm X 1cm, irregular shape Overlying mucosa - normal
62,63 and 24 Associated teeth vital No lymphadenopathy Radiograph impacted 22, 23; radio-opaque mass in apical region of 62,63 Clinical diagnosis complex composite odontome
Treatment done
Lesion enucleated
62,63 removed
examinaton Soft tissue cystic,roughly oval,1.5 X 1.5 cm Hard tissue fragments multiple,milky white, cone shaped resembling odontome.
Histopathology
Cystic epithelium overlying a connective tissue
capsule. Epithelium 6-8 cells thick with a prominent layer of columnar basal cells with hyperchromatic nuclei, polarised away from basement membrane. Superficial cells stellate reticulum Cystic epithelium presence of ghost cells Epithelium mural proliferations into cystic lumen Foci of calcification Connective tissue parallel collagen fibres with fibroblasts,endothelium lined blood vessels.
DIFFERENTIAL DIAGNOSIS
ODONTOME
AMELOBLASTOMA
AOT AMELOBLASTIC FIBROMA
Discussion
According to WHO typing of odontogenic tumors
of 1992, CEOC included under the heading of benign odontogenic tumors of odontogenic epithelium with odontogenic ectomesenchyme with or without dental hard tissue formation. It is thought to originate from odontogenic epithelial remnants within the jaw or gingiva. Age 2nd decade Equal sex predilection Site anterior regions
odontome Some consider CEOC cystic, others benign neoplastic counterpart to CEOC
HISTOLOGY:
polarised nuclei, stellate reticulum type cells on superficial layers and ghost cells
different patterns. Type IA Simple unicystic type Type IB Odontome producing Type IC Ameloblastomatous proliferating type Type II Neoplastic type, possesses some of the histologic features of CEOC and has been called dentinogenic ghost cell trumor
1991: I Cystic A- non proliferative B- proliferative C- ameloblastomatous D- associated with odontoma II Neoplastic A- ameloblastoma ex CEOC B- peripheral epithelial odontogenic ghost cell tumor C- central epithelial odontogenic ghost cell tumor
Calcifying odontogenic cyst (K Rajkumar, K Kamal, MR Sathish, S Leena Year : 2004 , Volume : 8 , Issue : 2 , 99-103)
Intraosseous calcifying cystic odontogenic tumor (Shikha Kler, Sangeeta Palaskar, Vishwa Parkash Shetty, Anju Bhushan JOMFP Year : 2009, Volume : 13, Issue : 1, Page : 27-29)
in the mandible of a 75-year-old male, with no reports of recurrence since its complete removal in September 2007.
References
Calcifying epithelial odontogenic cyst: a case report,
Journal of Oral and Maxillofacial Pathology vol.8,issue 1,Jan-Jun 2004 Shafers textbook of oral pathology 5th edition Neville, Damm oral and maxillofacial pathology,3rd edition Intraosseous calcifying cystic odontogenic tumor JOMFP Year : 2009, Volume : 13, Issue : 1, Page : 27-29) Calcifying odontogenic cyst Year : 2004 , Volume : 8 , Issue : 2 , 99-103)