Placenta Previa Abruptio

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Placenta Previa

Hai Ho, MD
Department of Family Practice

What is placenta previa?

Implantation of placenta over cervical os

Types of placenta previa

Who are at risk for placenta previa?


Endometrial scarring of upper segment of

uterus implantation in lower uterine


segment
Prior D&C or C-section
Multiparity
Advance age independent risk factor vs.
multiparity

Who are at risk for placenta previa?


Reduction in uteroplacental oxygen or

nutrient delivery compensation by


increasing placental surface area
Male
High altitude
Maternal smoking

Factors that determine persistence of


placenta previa?
Time of diagnosis or onset of symptoms
Location of placenta previa

Repeat ultrasound at 24 28
weeks gestation

Clinical presentations?
Painless vaginal bleeding 70-80%

1/3 prior to 30 weeks


Mostly during third trimester shearing force
from lower uterine segment growth and
cervical dilation
Sexual intercourse

Uterine contraction 10-20%

Fetal complications?
Malpresentation
Preterm premature rupture of membrane

Diagnostic test?

Ultrasound

Placenta Previa: ultrasound

Placenta

Placenta Previa: ultrasound

Placenta accreta?
Abnormal attachment of the placenta to the

uterine wall (decidua) such that the chorionic


villi invade abnormally into the myometrium
Primary deficiency of or secondary loss of
decidual elements (decidua basalis)
Associated with placenta previa in 5-10% of
the case
Proportional to the number of prior Cesarean
sections

Variations of placenta accreta

Placenta accreta: ultrasound

Vasa Previa?

Vasa Previa

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Vasa Previa

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Vasa Previa
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Vasa Previa
Rupture
Compression of vessels
Perinatal mortality rate

50 75%

Management of placenta previa?


Individualized based on (not much evidence):
Gestational age
Amount of bleeding
Fetal condition and presentation

Preterm with minimal or resolved


bleeding
Expectant management bed rest with

bathroom privilege
Periodic maternal hematocrit
Prophylactic transfusion to maintain
hematocrit > 30% only with continuous lowgrade bleeding with falling hematocrit
unresponsive to iron therapy

Preterm with minimal or resolved


bleeding
Fetal heart rate monitoring only with active

bleeding
Ultrasound every 3 weeks fetal growth, AFI,
placenta location
Rhogam for RhD-negative mother

Preterm with minimal or resolved


bleeding
Amniocentesis weekly starting at 36 weeks to

assess lung maturity delivered when lungs


reach maturity
Betamethasone or dexamethasone between
24 34 weeks gestation to enhance lung
maturity
Tocolysis magnesium sulfate

Active bleeding
Stabilize mother hemodynamically
Deliver by Cesarean section
Rhogam in Rh-negative mother
Betamethasone or dexamethasone between

24 34 weeks gestation to enhance lung


maturity

Management of placenta previa


No large clinical trials for the

recommendations
Consider hospitalization in third-trimester
Antepartum fetal surveillance
Corticosteroid for lung maturity
Delivery at 36-37 weeks gestation

Management of placenta accreta


Cesarean hysterectomy
Uterine conservation

Placental removal and oversewing uterine


defect
Localized resection and uterine repair
Leaving the placenta in situ and treat with
antibiotics and removing it later

Placenta Abruption

What is placental
abruption?
Premature separation of placenta from the
uterus

Epidemiology
Incident 1 in 86 to 1 in 206 births
One-third of all antepartum bleeding

Pathogenesis
Maternal vascular disruption in decidua

basalis
Acute versus chronic

Types of placental abruption


16%

81%

4%

Types of placenta hemorrhage

Risk factors for placental abruption?


Maternal hypertension
Maternal age and parity conflicting data
Blunt trauma motor vehicle accident and

maternal battering
Tobacco smoking and cocaine

Risk factors for placental abruption


Prior history of placental abruption

5-15% recurrence
After 2 consecutive abruptions, 25%
recurrence

Sudden decompression of uterus in

polyhydramnios or multiple gestation (after


first twin delivery) rare
Thrombophilia such as factor V Leiden
mutation

Clinical presentations?
Vaginal bleeding
Uterine contraction or tetany and pain
Abdominal pain
DIC

10-20% of placental abruption


Associated with fetal demise

Fetal compromise

Diagnostic test?
Ultrasound

Sensitivity ~ 50%
Miss in acute phase because blood could be
isoechoic compared to placenta
Hematoma resolution hypoechoic in 1 week
and sonolucent in 2 weeks

Blood tests

Ultrasound: subchorionic abruption

Ultrasound: retroplacental abruption

Ultrasound: retroplacental abruption

Blood tests?
CBC hemoglobin and platelets
Fibrinogen

Normal 450 mg/dL


<150 mg/dL severe DIC

Fibrin degradation products


PT and PTT

Management?
Hemodynamic monitoring

Urine output with Foley


BP drop late stage, 2-3 liter of blood loss

Fetal monitoring

Management: delivery
Timing

Severity of placental abruption


Fetal maturity - consider tocolysis with MgSO4
and corticosteroid (24-34 weeks)
Correction of DIC with transfusion of PRBC,
FFP, platelets to maintain hematocrit > 25%,
fibrinogen >150-200 mg/dL, and platelets >
60,000/m3

Mode: vaginal vs. Cesarean-section

Couvelaire uterus?
Bleeding into myometrium leading to uterine

atony and hemorrhage


Treatment
Most respond to oxytocin and methergine
Hysterectomy for uncontrolled bleeding

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