Packaging of Pharmaceutical Products
Packaging of Pharmaceutical Products
Packaging of Pharmaceutical Products
1 4/5/2011
CONTENTS:
PACKAGING
FUNCTIONS OF PACKAGING
TYPES OF PACKAGING
COMPONENTS OF PACKAGING
AEROSOL PACKAGING
CONTAINER & CLOSURES
PACKAGE TESTING
REFERENCES
2 4/5/2011
PACKAGING
Packaging has been defined as the means economically providing :-
• Presentation
• Identification
• Protection
• Convenience
3 4/5/2011
TYPES OF PACKAGING:
1. SOLID PRODUCTS
2. SEMI-SOLID PRODUCT
3. LIQUID PRODUCTS
4. UNIT PACKS
4 4/5/2011
1. SOLID PRODUCTS:
Solid dosages form such as tablets and capsules are by far the most commonly used today.
Traditionally they have been packed in bottles, originally made from glass but latterly from
various plastics.
The walls of the container are usually amber or completely opaque to minimize the
possibility of photo degradation.
Powder or granules have a variety of role when used as a final dosage form.
They usually packed as single dosages in flexible sachets.
5 4/5/2011
2. SEMI-SOLID PRODUCT
The relevant characteristics of these products for packaging purpose are that they are often too viscous
to flow but contain a sufficient amount of water to be classified as “wet ” products.
6 4/5/2011
3. LIQUID PRODUCTS
Traditionally glass has been the material of choice for the packaging of liquid but a
variety of plastics is now widely used providing they have little or no permeability to
the liquid
7 4/5/2011
UNIT PACKS:
Unit packs in which individual dosage are separated from each other are popular for
many type of dosage form.
8 4/5/2011
CHILD RESISTANCE PACKAGING:
9 4/5/2011
TAMPER RESISTANCE PACKAGING:
10 4/5/2011
COMPONENTS OF PACKAGING:
I. GLASS
II. METALS
III. RUBBERS
IV. PLASTICS
V. FIBROUS MATERIALS
11 4/5/2011
I. GLASS:
Glass is composed of sand, soda ash, limestone,& cullet.
Si, Al, Na, K, Ca, Mg, Zn & Ba are generally used into preparation of
glass
ADVANTAGE:
DISADVANTAGE:
12 4/5/2011
TYPE OF GLASS:
13 4/5/2011
PLASTICS:
14 4/5/2011
METALS:
The thickest aluminium is used for rigid containers. Eg. Aerosol cans
15 4/5/2011
RUBBERS:
Rubbers are excellent material for forming seals so they are used
almost exclusively to form closures such as bungs for vials or in
similar application such as gasket in aerosol can
These are consist of Two types:
a) NATURAL
b) SYNTHETIC
16 4/5/2011
FIBROUS MATERIALS:
Paper & board are used in various form for packaging of
pharmaceutical products.
They are used for preparing outer container such as cartons, boxes,
envelopes.
17 4/5/2011
FOIL, FILMS & LAMINATES
FOILS:
The most important metal for this application is aluminium.
FILMS
LAMINATES
18 4/5/2011
AEROSOL PACKGING
DISADVANTAGE:
19 4/5/2011
PARTS OF AEROSOL CONTAINER
I. CONTAINER
II. VALVE
III. ACTUATOR
20 4/5/2011
21 4/5/2011
CONTAINER AND CLOSURE
CONTAINER:
Pharmaceutical containers has been defined as a device that
holds the drugs or it may or may not be indirect contact with the
pharmaceutical preparation.
TYPES OF CONTAINERS
22 4/5/2011
CLOSURE:
An effective closure must prevent the contents from escaping & allow no
substance to the container.
TYPE OF CLOSURE:
A. PLUG TYPE
B. CROWN TYPE
C. PUSH FIT TYPE
D. SCREW TYPE
23 4/5/2011
24 4/5/2011
COMMON TYPE OF PACKAGING
1) BLISTER PACKAGING
2) STRIP PACKAGING
3) BUBBLE PACKAGING
25 4/5/2011
26 4/5/2011
REFERENCES:
I. Aulton Michael E., “Aulton’s Pharmaceutics The Design and Manufacture of Medicines”, Edited by
Churchill Livingstone Elsevier limited, 3rd edition,2007,pp 626-639.
II. Lachman leon, Lieberman Herbert A., Kanig Joseph L., “The theory & practice of industrial pharmacy”
published by Varghese publishing house, bombay, 3rd edition,1991,pp 711-732.
III. Cooper and Gunn’s, “Tutorial pharmacy”, edited by S.J.Carter,Publishing by CBS publisher &distributors,
Delhi, 6th edition, 2005,pp 131-141.
IV. Mehta R.M., “Pharmaceutics- 1”Published by vallabh prakashan, delhi, 2nd edition, pp 73-93.
V. http://www.ipapharma.org/events/Stability/JBhat.pdf (15/11/09)
27 4/5/2011
THANKYOU
28 4/5/2011
QUERIES????
??????
29 4/5/2011