Cell Division
Cell Division
Division
Mitosis And Meiosis
Why Do Cells Divide?
• For growth,
• repair,
• and reproduction
Mitosis
Organisms grow by the
addition of cells
In multicellular organism
some of these cells
perform functions
different from other cells.
The process of a cell
becoming different is
differentiation.
When do cells divide?
Most limiting factor in size is
the size of the cell membrane.
•Cells must obtain nutrients
•as volume increases, cell
surface area does not increase
as greatly
•larger cells require a larger
surface area for survival
Terminology
Chromatin - thin fibrous
form of DNA and proteins
Sister chromatids-
identical structures that
result from chromosome
replication, formed during
S phase
Anatomy of a Chromosome
How Do Cells Divide?
Cell cycle
–
sequence
of phases
in the life
cycle of
the cell
Cell Cycle Has Two Parts
Interphase
S or Synthesis stage
•DNA replicates
Interphase
G 2 or Gap 2
Interphase
Prophase
•Chromosome
condense
•Microtubles form
•The nuclear envelope
breaks down
Metaphase
Chromosomes
are pulled to
center of cell
Line up along
“metaphase
plate”
Anaphase
•Centromeres
divide
•Spindle fibers
pull one set of
chromosomes
to each pole
•Precise
alignment is
critical to
division
Telophase
•Nuclear envelope
form around
chromosomes
•Chromosomes
uncoil
•Cytokinesis
• animals - pinching of
plasma membrane
• plants- elongates and
the cell
• plate forms( future
cellwall and cell
membrane)
Meiosis
What is Meiosis?
A division of the nucleus that reduces
chromosome number by half.
Crossing over -
chromatids of tetrad
exchange parts.
Meiosis I
Prophase I
• Chromosomes
condense
• Homologous
chromosomes pair
w/ each other
• Each pair contains
four sister
chromatids - tetrad
Metaphase I
Tetrads or
homologous
chromosomes
move to
center of cell
Anaphase I
Homologous
chromosomes
pulled to
opposite poles
Telophase I
•Daughter
nuclei formed
•These are
haploid (1n)
Meiosis II
•Daughter cells undergo a
second division; much like
mitosis
NO ADDITIONAL
REPLICATION OCCURS
Prophase II
Spindle fibers form
again
Metaphase II
Sister chromatids move to the
center
Anaphase II
•Centromeres split
•Individual chromosomes are
pulled to poles
Telophase II &
Cytokinesis
Four haploid daughter cells results
from one original diploid cell
Review Mitosis &
Meiosis
• Both are forms of nuclear division