Oxygenation Objectives Recognition and Use of Oxyg EN

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OXYGENATION

OBJECTIVES
D US E OF O XY G E N
RECOGNITION AN

G EN DE LI VE RY DE V IC ES
HOW TO TO USE OXY
F OR D/ T D E LIV ER Y D EV IC ES
INDICATION
BASIC PRINCIPLE'S

• OXYGEN IS A DRUG

• IF ABUSED IT CAN CAUSE COMPLICATIONS

• WHY IS OXYGEN BEING ADMINISTERED

• WHAT ARE THE HAZARDS

• HIGH FLOW VERSUS VS LOW FLOW


DELIVERY EQUIPMENT

• NASAL CANNULA

• SIMPLE FACE MASK

• VENTURE MASK

• RESERVOIR BAG MASK


• OXYGEN REQUIRED TO PRODUCE ATP PROCESS OXIDATIVE PHOSPHORYLATION
• NO ENOUGH OXYGEN NO ATP= CELL DAMAGE CONDITION CALLED HYPOXIA
• HYPO: LESS THAN NORMAL OXIA=OXYGENATION

• SODIUM POTASSIUM PUMP STOPS


• ANAEROBIC GLYCOLYSIS STARTS 2ATP+LACTIC ACID(DENATURES PROTIEN) AND ACIDIC ENVIR
• CALCIUM PUMP STOPS(ENZYME ACTIVATION)
• FINALY ACTIVATES CYTOCHROME C APOPTOSIS(SELF DISRTUCTION)
HYPOXIA
• SYMPTOMS HEAD ACHE SIGNS TACHYCARDIA
CONFUSION HYPOTENSION
BEHAVIORAL CHANGE PULMONARY HYPERTENSION
BREATHLESSNESS CARDIAC ARRHYTHMIA
DROWSINESS METABOLIC ACIDOSIS WITH RESPIRATORY
TIREDNESS ALKALOSIS
CYANOSIS ANAEROBIC GLYCOLYSIS
HYPOXIA

• CONDITION IN WHICH BODY IS DEPRIVED OF OXYGEN

• A DECREASE BELOW NORMAL LEVELS OF OXYGEN IN INSPIRED GASES, ARTERIAL BLOOD OR TISSUE WITH
OUT REACHING ANOXIA
CAUSES OF HYPOXIA
• HIGH ALTITUDE
• DECREASED O2 SUPPLY TO AN AREA
• LOW HEMOGLOBIN LEVEL
• LOW OXYGEN CARRYING CAPACITY
• POOR TISSUE PERFUSION
• IMPAIRED VENTILATION
• DECREASED DIFFUSION OF O2
TYPES OF HYPOXIA
TERMS: ARTERIAL PO2,O2 CARRYING CAPACITY OF BLOOD(HB VALUE),A-V D/CE OF PO2
PERCENTAGE SATURATION OF HEMOGLOBIN SAO2

• HYPOXEMIC HYPOXIA

• ANEMIC HYPOXIA

• STAGNANT HYPOXIA

• HISTOTOXIC HYPOXIA
HYPOXEMIC HYPOXIA
• DECREASED AMOUNT OF BREATHABLE O2- DECREASED PARTIAL PRESSURE OF 02
- DECREASED O2 CONCENTRATION
CAUSES LEAKING MASK IN ADEQUATE REGULATOR FUNCTION,FAULTY HOSE CONNECTIONS

• PULMONARY FAILURE IMPAIRED GAS EXCHANGE IN THE LUNGS


- PNEUMONIA
- INTERSTITIAL LUNG DISEASE
-DIRECT BLOCK AGE
- COPD
CHARACTERISTICS
• DECREASED O2 SATURATION IN BLOOD

• A-V PO2 D/CE IS LOW

• LOW ARTERIAL O2 CONTENT

• LOW ARTERIAL PO2

• TISSUE UTILIZATION IS NORMAL

• BLOOD FLOW TO TISSUES NORMAL

• O2 CARRYING CAPACITY IS NORMAL


ANEMIC HYPOXIA
• DECREASEAD NO OF RBCS
• DECREASED HEMOGLOBIN CONTENT IN THE BLOOD
• FORMATION OF ALTERD HEMOGLOBIN
• COMBINATION OF HEMOGLOBIN WITH OTHER GASSES THAN O2 & CO2
• RBC’S TRANSPORT O2
DEC NO OF RBCS= LESS O2 AVAILABLE TO THE TISSUES
RBCS FULLY SATURATED BUT LESS O2 AVAILABLE TO THE TISSUES
CO POISONING DISPLACES O2 AND BINDS HEMOGLOBIN
RESULTS FROM SPO2 ARE MISLEADING IN THIS CASE
CHARACTERISTICS

• 02 CARRYING CAPACITY OF THE BLOOD IS LOW


• ARTERIAL PO2 NORMAL
• A-V D/CE NORMAL
• NORMAL TISSUE UTILIZATION
STAGNANT HYPOXIA
• BLOOD CIRCULATION THROUGH THE TISSUE IS REDUCED(DISTRIBUTION PROBLEM)
• GENERALIZED: PUMP FAILURE –HEART ATTACK (FAINTING,SHOK)
• HIGH G FORCES
--ABNORMAL RHYTHM
--VALVULAR HEART DISEASE
--OUT FLOW OBSTRUCTION
LOCALIZED: BLOOD SUPPLY REDUCED TO LOCAL AREA –ARTERIOSCLEROSIS
-- THROMBUS
--EMBOLUS(FAT,GAS,CLOT)
-- COLD
-- SEVER INFECTION
• NORMAL PO2

• NORMAL SAO2

• A-V D/CE IS HIGHER THAN NORMAL


HISTOTOXIC HYPOXIA
• UTILIZATION PROBLEM(TISSUES CANT USE SUPPLIED O2)

• MITOCHONDRIA UNABLE TO UTILIZE OXYGEN(NO ATP)

• CAUSES: CYANIDE POISONING-MURDER MYSTERY(CYTOCHROME OXIDASE)

• ALCOHOL &BARBITURATE

• O2 TOXICITY(INHIBITION OF CERTAIN ENZYMES HAMPERING O2 METABOLISM)CYTOCHROME OXIDASE


- BURN FROM PLASTICS OR FABRICS
STOPS OXIDATIVE PHOSPHORYLATION
CHARACTERISTICS

• NORMAL PO2

• NORMAL SAO2

• A-V D/CE IS NIL


LEVELS OF HYPOXEMIA
• MILD PAO2 OF 60-80 MMHG SPO2 OF 91-95 %

• MODERATE PAO2 OF 40-60 MMHG SPO2 OF 74-91 %

• SEVERE PAO2 OF < 40 MMHG SPO2 0F < 74 %

• PHYSICAL ASSESSMENT INSPECTION


PALPATION
AUSCULTATION
TARGET SATURATIONS

• AIM FOR 94%-98% IN MOST PATIENTS


• 88%-92% IF AT RISK OF TYPE II RESPIRATORY FAILURE (HIGH CO2 & LOW O2)
• ADAPT OXYGEN DELIVERY DEVICE & FLOW RATE
NASAL CANNULA
• EXACT FIO2 DELIVERED?
• 1L/MIN =24% THEN EACH L ADDS APPROX 4%
• USE 1-6 L/MIN THAT GIVES APPROXIMATELY 24%-50% FIO2
• CONSIDER HUMIDIFICATION FOR >4 L/MIN
• INDICATION: LOW TO MODERATE OXYGEN REQUIREMENT
• ADVANTAGES: ALLOW ORAL FREEDOM,EASILY TOLERATED ,NO REBREATHING, LOW COST
• DISADV: EASILY DIALOGED & MOUTH NOT COVERED
SIMPLE FACE MASK
• INDICATION : LOW FLOW DELIVERY DEVICE
FOR LOW TO MODERATE OXYGEN REQUIREMENT

• FLOW RATE: 5-10 L/MIN

• OXYGEN DELIVERY VARIABLE(40%-70%)

• ASSES FACIAL SKINS AND BEHIND THE EAR

• MAY MAKE THE PATIENT FEEL CLAUSTROPHOBIC


VENTURI MASK
• INDICATION: HIGH FLOW O2 DELIVERY
• SPECIFIC MODERATE OXYGEN REQUIREMENT (EG. COPD)
• FLOW RATE SPECIFIC TO ADAPTOR(4-12)
• OXYGEN DELIVERY: MORE PRECISE FIO2 DELIVERY
24%-60% BASED ON THE ADAPTER USED
HAVE COLOR CODED ADAPTER FOR SPECIFIC PERCENTAGE
ENSURES EXACT PERCENTAGE OF O2 DELIVERY
USED WITH THE PATIENT WHO RETAIN CO2
BEST FOR COPD
RESERVOIR BAG

• INDICATION: HIGH OXYGEN REQUIREMENT

• FLOW RATE: 12-15L/MIN

• OXYGEN DELIVERY: 60%-80%


NON REBREATHER MASK
• LOW FLOW DELIVERY DEVICE
• VALVES ON MASK MAKE EXHALED AIR TO LEAVE THE MASK
• THE RESERVOIR CONTAINS ONE WAY VALVE PREVENT EXHALED AIR FROM ENTERING
• FITS SNUGLY TO THE FACE
• FLOW RATE: 10-15 L/MIN
• OXYGEN DELIVERY: 60%-100%
OXYGEN THERAPY IN ACUTE HYPOXIA
IS THE PATIENT
CRITICALLY ILL OR IN A
PERI-ARREST CONDITION

IS THE PATIENT AT RISK OF TYPE II COMMENCE TREATMENT


(HYPERCAPNIC) RESPIRATORY FAILURE WITH RESERVOIR BAG

TARGET SATURATION IS 88%-92% WITH


TARGET SATURATION
AWAITING BLOOD GAS RESULTS
94%-98%
FRACTION INSPIRATORY O2 FROM FLOW RATE(L/MIN)
Nassal cannula(low flow) Simple mask (low flow) Venturi mask(low flow) Partial non breather(high
flow)
l/min %o2 l/min %o2 l/min %o2 l/min %o2
1 24 5-6 40 4 24 6 60
2 28 6-7 50 4 28 7 70
3 32 7-8 60 8 35 8 80
4 36 8 40 9 90
5 40 12 50 10-12 >95
6 44 12 60
TRACHEAL AIR WAYS

AIR WAYS THAT GO IN TO TRACHEA

• ENDO TRACHEAL TUBE :SEMI RIGID CURVED TUBES WITH CUFF AT THE DISTAL END

• TRACHEOSTOMY TUBE : PLACED DIRECTLY ON THE TRACHEA TO CONTROL THE AIR WAYS
SUCTIONING

• DONE WHEN THE PATIENT ARE HAVING DIFFICULTY OF CLEARING AIR WAYS
• SECRETIONS ARE REMOVED VIA A CATHETER CONNECTED TO SUCTION SOURCE
• OROPHARYNGEAL/NASOPHARYNGEAL WHEN THE PATIENT CANNOT EFFECTIVELY COUGH SECTIONS
• OROTRACHEAL/NASOTRACHEAL USED WHEN THE PATIENT UNABLE TO MANAGE SECRETIONS
• TRACHEOSTOMY/ENDOTRACHEAL USED WITH ARTIFICIAL AIR WAYS
• ASSUMES NORMAL RESPIRATORY RATE OF 12-20 BREATHES PER MINUTE

• LOW FLOW SYSTEMS: FIO2 DELIVERED TO PATIENT IS VARIABLE & UNPREDICTABLE

• HIGH FLOW DEVICES: FIO2 DELIVERED TO PATIENT IS CONSISTENT & RELIABLE


• VENTILATION: INSPIRATION & EXPIRATION

• RESPIRATION: EXCHANGE OF GASSES IN THE LUNG

• COMPLIANCE: LUNGS ABLE TO INFLATE(EDEMA)

• ELASTIC RECOIL: FIBERS ABLE TO RETURN TO ORIGINAL POSITION (EMPAYSEMA)

• AIRWAY RESISTANCE: RESISTANCE TO FLOW AIR IN THE AIR WAYS


ADEQUATE OXYGENATION OF TISSUES IS DEPENDENT ON

CARDIOVASCULAR AND RESPIRATORY SYSTEM WORKING TOGETHER TO OXYGENATE SYSTEMS

• TO DELIVER OXYGEN TO BLOOD STREAM REQUIRES HEALTHY RESPIRATORY SYSTEM


• TO CIRCULATE OXYGEN BODY REQUIRES INTACT CARDIOVASCULAR SYSTEM
CV ALTERATION ON OXYGENATION

• HEART NOT GOOD= LOW CIRCULATION=DECREASED O2 LEVEL IN TISSUES

• INTERRUPTION OF BLOOD FLOW CAUSED BY


CARDIAC RHYTHM IRREGULARITIES
HEART FAILURE
NARROWING OF ARTERIES(ARTHEROSCLEROSIS,SPASM,ONGENTIAL MALFORMATIION)
RESPIRATORY ALTERATIONS
• CHRONIC OBSTRUCTIVE PULMONARY DISEASE( COPD)
DISORDERS CHARACTERIZED BY IMPAIRED AIR FLOW IN THE LUNGS
EMPHYSEMA
BRONCHITIS
PNEUMONIA
ATELECTASIS
SYMPTOMS OF CARDIO PULMONARY ALTERATIONS

• DECREASED OXYGENATION

• SHORTNESS OF BREATH

• DIFFICULTY WHEN BREATHING

• CARDIAC AND RESPIRATORY PROBLEM HISTORY


OBJECTIVE DATA
• VITAL SIGN: BP,SPO2,PR,TEMP

• ARTERIAL PO2,OXYGEN CARRYING CAPACITY OF BLOOD(HB VALUE), PERCENTAGE SATURATION OF HEMOGLOBIN

• CHEST VISUAL INSPECTION

• PALPATION FOR CARDIAC ENLARGEMENT OR ABNORMAL VIBRATION

• AUSCULTATION OF HEART SOUNDS

• AUSCULTATION OF THE LUNGS

• ASSESSMENT OF VASCULAR(EDEMA)ON EXTREMITIES

• ASSESSMENT OF PULSES, SKIN COLOR & PULSES


LABORATORY DIAGNOSTIC TEST
• CBC: PROVIDE INFORMATION FOR BLOOD O2 & CO2 TRANSPORT CAPACITIES AND STATUS OF IMMUNE
RESPONSE

• ABG: ASSES OXYGENATION & ACID BASE IMBALANCE

• CARDIAC ENZYMES: IF CHEST PAIN OR RELATED SYMPTOM TO DETERMINE HEART DAMAGE

• LIPIDS: HYPERLIPIDEMIA RISK FACTOR FOR CORR HEART DISEASE


NORMAL ARTERIAL BLOOD GAS LEVELS
Pao2 80-100 mmhg
Paco2 35-45 mmhg
Ph 7.35-7.45
Hco3 22-26 meq/l
Base excess 2
PROMOTING OPTIMAL CARDIO PULMONARY

• GOAL OF OXYGEN THERAPY : DECREASE SYMPTOMS RELATED TO LOW OXYGEN LEVEL & CV SYSTEM
OVERLOAD

• ASSESSMENT INCLUDES LAB RESULTS TO DOCUMENT HYPOXEMIA


• HYPOXEMIA MANIFESTED BY HIGH RESPIRATORY , HEART RATE OR CYANOSIS DECREASING O2
SATURATION AND DISTRESS
PRECAUTIONS IMPORTANT WHEN ADMINISTERING O2

• PATIENT WITH CHRONIC HYPERCAPNIA MAY HAVE A RESPIRATORY DIPRESSION WHEN SUPPLEMENTAL
O2 LEVELS ARE TO HIGH

• WHEN FIO2 LEVELS >50% ATELECTASIS OR OXYGEN TOXICITY MAY OCCUR

• HIGH LEVELS OF OXYGEN POSE A FIRE HAZARD

• NEBULIZERS & HUMIDIFIERS MAY HAVE BACTERIAL CONTAMINATION LEADING TO INFECTION


DEVICES USED TO DELIVER O2

• CATEGORIZED IN TO LOW FLOW (ROOM AIR IS BREATHED IN)


RESERVOIR
HIGH FLOW
HYPOVENTILATION
• DELIVERY OF AIR TO ALVEOLI OF THE LUNGS IS INSUFFICIENT TO MEET THE BODY NEEDS OF GETTING OXYGEN AND
REMOVING CO2

• DECREASED RATE & DEPTH OF BREATHING


• THUS IT RESULTS INCREASED LEVELS OF CO2(45 MMHG) & RESULTANT HYPOXEMIA DUE TO HIGH LEVEL OF CO2
DISPLACING ALVEOLAR O2
SYMPTOMS
BREATHLESSNESS & CHEST TIGHTNESS
CAUSES: PARALYSIS OF RESP MUSCLES, OBSTRUCTIVE SLEEPING APPNEA, OBESITY DRUGS
HYPERVENTILATION
• INCREASE IN THE AMOUNT OF AIR ENTERING ALVEOLI RESULTING REDUCED LEVEL OF CO2 IN THE
BLOOD(HYPOCAPNIA)

• WHEN PERIPHERAL CHEMORECEPTORS ARE ACTIVATED BY HYPOXIA WE HAVE HYPER VENTILATION


SYMPTOMS
SHORTNESS OF BREATHE(25-40),LIGHTHEADED, RAPID HEART RATE
COUSE :PAIN, FEVER, ANXIETY, OBSTRUCTIVE& RESISTIVE LUNG DISEASES,SEPSIS,
TREATMENT OF HYPOXIA

• 100% OXYGEN
PREVENTION OF OXYGEN
• INCREASING CONCENTRATION/PRESSURE OF OXYGEN

• PRICE CHECK PRESSURE

• REGULATOR
INDICATOR
CONNECTION
EMERGENCY O2 SYSTEM

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