Lab Activity 4: Classification of Tissues Martini Chapter 4

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Lab Activity 4

Classification of Tissues
Martini Chapter 4

Institut Pendidikan Guru, KPM


PJM3106 Anatomi dan Fisiologi
Tissues
• Groups of cells similar in structure and function
• Each tissue is then further subdivided into
categories.
• All organs are made of a combination of
different tissues.
• The four types of tissues
• Epithelial
• Connective
• Muscle
• Nerve
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Epithelial Tissue
Distinguishing Characteristics

1. Cellularity: Composed almost entirely of cells


2. Polarity: apical and basal surfaces (top and a
bottom)
3. Attachment: Supported by connective tissue
(basement membrane)
4. Avascular: Contains no blood vessels: obtains
nutrients by diffusion
5. Regeneration: Rapidly replaces lost cells by
cell division
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Classification of Epithelia
1. First name:
• Simple: one layer
• Stratified: more than one layer
2. Second name:
• Based on the shape of the top layer of cells
• Squamous (flat)
• Cuboidal (square)
• Columnar (rectangle)
3. Two additional categories
• Transitional
• Pseudostratified 4
Classification of Epithelia

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Classification of Epithelia

• Squamous

• Cuboidal

• Columnar

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Simple Squamous Epithelium
• Single layer of flattened cells with disc-
shaped nuclei and sparse cytoplasm

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Simple Squamous Epithelium

• Top View

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Simple Squamous Epithelium

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Simple Squamous Epithelium
• Functions:
1. Diffusion
• Alveoli in the respiratory system allows for
exchange of O2 and CO2
2. Filtration
• Capillaries allow fluid and other substances
out and holds blood cells and proteins in
3. Lubrication
• Secretes lubricating substances in serosae
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Simple Cuboidal Epithelium
• Single layer of cube like cells with large,
spherical central nuclei

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Simple Cuboidal Epithelium

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Simple Cuboidal Epithelium
• Functions:
1. Secretion
• Glands such as the thyroid are composed of
simple cuboidal epithelium and secrete
hormones ect…
2. Absorption
• In the kidney, the proximal convoluted
tubule is composed of simple cuboidal
epithelium and reabsorbs water and other
nutrients from the filtered fluid
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Simple Columnar Epithelium

• Single layer of tall cells with oval nuclei toward


the basal surface
• Goblet cells are often found in this layer

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Simple Columnar Epithelium

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Simple Columnar Epithelium

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Simple Columnar Epithelium
• Functions
1. Secretion
• Example: In the stomach, these cells
secrete digestive enzymes
2. Absorption
• Example: In the intestine, these cells
absorb nutrients

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Pseudostratified Columnar
Epithelium
• Single layer of cells with different heights;
some do not reach the free surface
• Nuclei are seen at different levels
• May be ciliated (PCCE) or non-ciliated

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Pseudostratified Columnar
Epithelium

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Pseudostratified Columnar
Ciliated Epithelium (PCCE)

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Pseudostratified Columnar
Ciliated Epithelium (PCCE)
• Functions
1. Protection
• Example: Lines the upper respiratory tract.
The cilia sweep debris toward the throat
2. Secretion
• Example: May contain goblet cells
(unicellular glands) that secrete mucus

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Stratified Squamous Epithelium
• Composed of several layers of cells
• Top layer flat
• Bottom layers any shape
• Function in protection of underlying areas
subjected to abrasion

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Stratified Squamous
Epithelium

•Non-keratinized
•Composed of several
layers of cells
•Top layer flat
•Bottom layers any
shape

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Stratified Squamous Epithelium
Non-Keratinized

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Stratified Squamous Epithelium
Non-Keratinized
• Functions
1. Physical protection against abrasion and
pathogens
• Non-Keratinized is associated with “moist”
areas
• Mouth
• Throat
• Esophagus
• Anus
• Vagina
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Stratified Squamous Epithelium
Keratinized

Looks
“flakey” on
the top

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Stratified Squamous Epithelium
Keratinized

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Stratified Squamous Epithelium
Keratinized
• Functions
1. Physical Protection
• Found only in the epidermis of the skin
• Keratin is a protein that helps strengthen
the cells against abrasion

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Transitional Epithelium
• Several cell layers, basal cells are cuboidal
• Apical cells are dome shaped when not
stretched
• Apical cells are flat when stretched
• Only found in Urinary System
• Functions:
1. Allows expansion and recoil after stretching

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Transitional Epithelium

Distended bladder Empty bladder

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Stratified Cuboidal and Columnar

• Typically two cell layers thick


• Rare

• Functions:
1. Secretion
• Found in some sweat and mammary glands

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Stratified Cuboidal Epithelium

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Stratified Cuboidal Epithelium

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Stratified Columnar Epithelium
• Limited distribution in the body
• To tell the difference between this and
pseudostratified columnar, look at the nucleus.
• The nuclei are lined up in a straight row

• Function
1. Protection
• Found in the pharynx, male urethra, lining
some glandular ducts, and anus

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Stratified Columnar Epithelium

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Stratified Columnar Epithelium

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Connective Tissue

• 4 Types
1. Connective Tissue Proper
2. Bone
3. Blood
4. Cartilage

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Connective Tissue Features
1. Specialized cells
2. Matrix: Nonliving material between the cells
that makes up most of the volume (ground
substance + fibers)
• Extracellular fibers
• Ground substance: Composed chiefly of
interstitial fluid, cell adhesion proteins, and
proteoglycans
• Specific composition varies between
tissues (Blood=fluid, Cartilage=gel like,
Bone=Solid)
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Connective Tissue Fibers
• Collagen Fibers: Fibrous protein
molecules
• Extremely tough
• High tensile strength
• Strongest type of fibers in connective
tissue.

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Connective Tissue Fibers
• Elastic Fibers: Form branching networks
• Elastin: a rubber like protein that allow it to act like
a rubber band and snap back to its original shape
after it is stretched
• Reticular Fibers: Forming delicate networks
• Fine collagenous fibers (with a different
chemical structure) branch extensively
• Surround small blood vessels and
support soft tissue organs

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Cells of Connective Tissue Proper
1. Fibroblasts: Secrete the matrix
2. Macrophages: Scavenger cells that engulf
pathogens or damaged cells
3. Adipocytes: Fat cells
4. Mesenchymal Cells: Stem cells
5. Mast cells: Stimulate local inflammation:
contain histamine and heparin
6. Lymphocytes/microphages: WBC involved in
immunity 43
Areolar Connective Tissue (Loose)
• Gel like matrix
• Contains all 3 fiber types
• Functions:
1. Wraps and cushions organs
2. Holds and conveys tissue fluid
• Locations:
1. Under epithelial tissues
2. Packages organs
3. Surrounds capillaries
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Areolar Connective Tissue (Loose)

Fibroblast

Collagen fiber

Macrophage

Elastic fiber

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Adipose Tissue (Loose)
• Function:
1. Storage of lipid
molecules
2. Insulation

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Reticular Connective Tissue (Loose)
• Network of reticular fibers in a loose
ground substance
• Functions
1. Soft internal skeleton that supports other cell
types
• Locations
1. Lymph nodes
2. Bone marrow
3. Spleen
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Reticular Connective Tissue (Loose)

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Dense Regular Connective Tissue
• Primarily parallel collagen fibers
• Major cell type: fibroblast
• Functions:
1. Withstands great tensile stress pulling in one
direction
• Locations:
1. Tendons
2. Ligaments
3. Aponeuroses
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Dense Regular Connective Tissue

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Dense Irregular Connective Tissue
• Irregularly arranged collagen fibers
• Functions:
1. Withstands tension exerted in many directions
2. Provides structural strength
• Locations:
1. Dermis of skin
2. Submucosa of digestive tract
3. Fibrous capsules of organs and joints
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Dense Irregular Connective Tissue

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Elastic Connective Tissue (Dense)
• Dense regular CT dominated by elastic fibers
• Functions:
1. Stabilizes positions of vertebrae and penis
2. Cushions and permits expansion and
contraction of organs
• Locations:
1. Between vertebrae
2. Ligaments supporting penis, transitional
epithelia
3. Blood vessel walls
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Elastic Connective Tissue (Dense)

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Blood: Hematopoietic Tissue
• Functions:
1.Transportation
2.Immunology
3.Hemostasis

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Bone: Osseous Tissue
• Functions:
1.Lever for muscles
2.Mineral storage
3.protection

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Hyaline Cartilage
• Functions:
1.Stiff but flexible support
2.Reduces friction
between bony surfaces
• Locations:
1.Articular surfaces
2.Larynx
3.Trachea
4.Nasal septum
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Elastic Cartilage
• Functions:
1. Support, but
flexible
• Locations:
1. Ear
2. Epiglottis

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Fibrocartilage
• Functions:
1. Resists
compression
2. Prevents bone-to-
bone contact
• Locations:
1. Meniscus of knee
2. Pubic symphysis
3. Intervertebral
discs 59
Skeletal Muscle
• Voluntary
• Multiple
peripheral
nuclei
• Striated

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Skeletal Muscle:
Peripheral Nuclei

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Cardiac Muscle:
Arrow: Intercalated Discs
• One or two
central nuclei
• Striated
• Involuntary
• Found only in
the heart

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Smooth Muscle
• One central
nuclei
• No striations
• Involuntary
• Found in
hollow
organs,
blood vessels

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Nervous Tissue

• Functions:
1. Neurons: Electrical signaling
2. Glial cells: Support of neurons 64
Nervous Tissue

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The End

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