Astaxanthin in COVID-19

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Astaxanthin in COVID-19:

the crucial role of early


treatment in avoiding
disease progression
Wiwin Is Effendi, PhD
Pendahuluan
• SARS-CoV-2
share almost
80% (SARS-
CoV) & 50%
(MERS- CoV)

Respir Res (2020);21: 224
• Mechanisms of
SARS-CoV-2-
mediated
inflammatory
responses

Virologica Sinica (2020); 35:266–271


Respir Res (2020);21: 224
Cell Research (2020); 30:367–369

• The antioxidant
should be
administered
early in the
course of
disease.

Physiol Rev 100: 1455–1466


Patogenesis COVID-19
Physiology (2020);35: 288-301
Respons
imun

Signal Transduction and Targeted


Therapy (2020); 5:128
Badai sitokin

Front. Immunol (2020);11:1648


Front. Immunol.(2020) 11:598444.
Oksidatif
stress

Diseases (2021); 9: 17
Nat. Medicine (2020);26: 1017-1032
Astaxanthin sebagai
terapi suplemen
tambahan potensial
Astaxanthin (ASX):
karotenoid sekunder
berwarna merah
cerah yang disintesis
secara de novo oleh
beberapa jenis
mikroalga, tanaman,
ragi, bakteri, dan
pada sumber
makanan laut, seperti
salmon, udang, dan
telur ikan yang
memiliki efek super-
antioksidan

J Mol Pathophysiol (2018);7(1): 1-6


Mar. Drugs (2016); 14: 35
Anti-
inflamasi

Molecules (2020); 25: 5342


Anti-oksidan

J Aging Sci (2019); 7: 211


Immuno-
modulator

Mar. Drugs (2020); 18: 351


Anti-
apoptosis
dan autofagi

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