Cataracts
Cataracts
Cataracts
INTRODUCTION
• A cataract is a lens opacity or cloudiness.
• Cataracts rank only behind arthritis and heart
disease as a leading cause of disability in older
adults.
• Cataracts affect about one in every six people
who are 40 years of age or older.
• According to the World Health Organization,
cataract is the leading cause of blindness in the
world.
DEFINITION
• A cataract is an opacity in the lens of the eye
that may cause a loss of visual acuity.
• Vision is diminished because the light rays are
unable to get to the retina through the
clouded lens.
TYPES
• Aging
• Loss of lens transparency
• Clumping or aggregation of lens protein (which leads to
light scattering)
• Accumulation of a yellow-brown pigment due to the
breakdown of lens protein
• Decreased oxygen uptake
• Increase in sodium and calcium
• Decrease in levels of vitamin C, protein, and glutathione
(an antioxidant)
CONT’D
• Associated Ocular Conditions
• Retinitis pigmentosa
• Myopia
• Retinal detachment and retinal surgery
• Infection (e.g. herpes zoster, uveitis)
• congenital defects.
CONT’D
• Toxic Factors
• Corticosteroids, especially at high doses and in
long-term use
• Alkaline chemical eye burns, poisoning
• Cigarette smoking
• Calcium, copper, iron, gold, silver, and
mercury, which tend to deposit in the
pupillary area of the lens
CONT’D
• Nutritional Factors
• Reduced levels of antioxidants
• Poor nutrition
• Obesity
• alcohol consumption
CONT’D
• Physical Factors
• Dehydration associated with chronic diarrhea,
use of purgatives in anorexia nervosa, and use
of hyperbaric oxygenation
• Blunt trauma, perforation of the lens with a
sharp object or foreign body, electric shock
• Ultraviolet radiation in sunlight and x-ray
CONT’D
• Systemic Diseases and Syndromes
• Diabetes mellitus
• Down syndrome
• Disorders related to lipid metabolism
• Renal disorders
• Musculoskeletal disorders
CLINICAL MANIFESTATIONS