Poster Laura BUCURESTI
Poster Laura BUCURESTI
Poster Laura BUCURESTI
Eugenia Laura Lucan 1, Ioana Andreea Gheonea2, Ștefan Cristian Dinescu1, Sarmis Marian Săndulescu 3 , Roxana Mihaela Dumitrașcu1, Mihaela Stănciugel1 , Tudorel Ciurea4 , Larisa Daniela Săndulescu 1,4
1 Department of Internal Medicine, Emergency County Hospital Craiova, Romania, 2 Radiology and Imaging Department, County Hospital Craiova , Romania, 3 Surgery Department, Emergency County Hospital Craiova, Romania
4 Research Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy Craiova
BAKGROUND
Hepatocellular carcinoma (HCC) is one of the most frequent type of primary liver cancer with high mortality witch presents lungs, bone and lymph node metastasis. In a few cases HCC determined spleen
metastases, almost 0,8%.
METODOLOGY
DISCUSSION
• In CEUS, both liver lesions present inomogenous and chaotic enhancement in arterial phase with wash-out slowly and uncompleted in portal phase, sugesting
hepatocellular carcinoma, LIRADS V (LIRADS classification) and the splenic lesion, in clinical context, was suggestive for splenic secondary determinations.
• Computer tomography and AFP with high level, and clinical aspects in a patient with liver cirrhosis sustained our diagnosis.
• The patient received treatment with Sorafenib 800mg/zi, from july 2015 until present, with partial response, conform RECIST criteria, with regression of
viable tumor lesions.
CONCLUSIONS:
CEUS represents a non invasive and accessible ultrasonography method with high sensibility and sensitivity for
diagnosis and monitoring of patients with HCC and secondary determinations.
Ussualy the spleen metastasis are represented more frecvent by ovarian cancer, gastric and colon cancer in rare cases.
It is uncommon splenic metastasis from hepatocellular carcinoma, being reported in literature, below 1% of cases.