Probiotics
Probiotics
Probiotics
Dr.T.V.Rao MD
DR.T.V.RAO MD
At the start of the 20th century, Russian Nobel prize winner and father of modern immunology, Elie Metchnikoff, a scientist at the Pasteur Institute, was the first to conceptualize Probiotics
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INTESTINE IS A PARADISE OF DISEASES Death sits in the bowels; a bad digestion is the root of all evil Hippocrates, ca. 400 BC
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Prebiotic - (greek - before life) a substance (usually an oligosaccharide) that cannot be digested but does promote the growth of beneficial bacteria or probiotics
Probiotic - (for life) a substance that contains microorganisms or bacteria that are beneficial to the host organism.
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DEFINING A PROBIOTIC
The term probiotic comes from the Latin or Gree pro, before, forward, and bios, or life thus probiotics are life-promoting. In this case, we use the term probiotics to refer to beneficial bacteria
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HISTORY OF PROBIOTICS
Bulgarian yoghurt (sour milk), commonly consumed plain, is popular for its taste, aroma, and quality. The qualities arise from the Lactobacillus bulgaricus and Streptococcus thermophilus culture strains used in Bulgaria
In 1907 Metchnikoff proposed that the acid producing bacteria in fermented milk products could prevent fouling" in the large intestine and, if consumed regularly, lead to a longer, healthier life.
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Yakult
In 1935 he started marketing Yakult as a
probiotic yogurt-like product made by fermenting a mixture of skimmed milk with
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DR.T.V.RAO MD
, prebiotics are nutrients that the bacteria use as a fuel source; these include dietary fiber and carbohydrates
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competition for chemicals/available energy competition for adhesion sites (exclusion) enhancement of the immune response improvement of water quality interaction with phytoplankton a source of macro- and micro-nutrients enzymatic contribution to digestion
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Competitive exclusion Production of Bacteriocins Production of organic acids Altered absorption of the intestinal mucosa
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Lactobacillus ramnosus
Lactobacillus paracasei Lactobacillus plantarum Lactobacillus bulgaricus Bifidobacterium infantis Bifidobacterium longum Bifidobacterium breve Streptococcus Thermophilus
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PROBIOTIC RESEARCH
Allergies - certain probiotics have an impact on the mucosal barrier function of the intestinal tract. This effects allergens entering the body and the activity of inflammation producing cells Cholesterol regular consumption of certain probiotic dairy products may have an impact on cholesterol level and may affect the levels of good HDL in the blood Colon Cancer Certain probiotics may help prevent colon cancer by preventing the breakdown of enzymes that contribute to the growth of cancer causing agents
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PROBIOTIC RESEARCH
Infant Health Mother nature has long recognized the benefits of Probiotics. Human breast milk contains a protein that stimulates the growth of good bacteria to help with digestion. Therefore a way to create and maintain a perfect balance of gut bacteria in babies has been in existence for as long as babies have been born Probiotics in Infant Formulas with the added protective benefit of beneficial probiotic cultures like those naturally promoted by breast milk, help support Babys healthy immune system. High levels of Bifidobacteria in the digestive tract are thought to be one of the reasons why breastfed babies are generally so healthy
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PROBIOTIC RESEARCH
Continued clinical research to study the benefits of probiotics in the areas of :
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PROBIOTIC RESEARCH
Acne treatment and clearer skin (maintaining a healthy balance of beneficial intestinal micro flora) Cancer control (bind, block or remove carcinogens, activate the hosts immune system to antitumor genesis, inhibit bacteria that directly or indirectly convert procarcinogens to carcinogens) Animal health (boost immune system, maintain balance of intestinal microflora)
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MARKETING OF PROBIOTICS
Most probiotic products contain bacteria from the genera Lactobacillus or Bifidobacterium, although other genera, including Escherichia, Enterococcus, Bacillus and Saccharomyces (a yeast) have been marketed as probiotics. Some commercial probiotic products which contain Bacillus are incorrectly labelled with a name not recognized by the scientific community, 'Lactobacillus sporogenes
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Programme Created by Dr.T.V.Rao MD for Medical and Premedical Students in the Developing World
Email
[email protected]
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