The document provides an overview of ultrasound physics and optimization for ultrasound-guided regional anesthesia. It discusses the basics of sound waves and how they interact with tissues. Key points include: the piezoelectric effect which converts mechanical energy to electrical energy; acoustic impedance and how it affects reflection and refraction; and factors that influence image quality such as transducer selection, gain, depth, and angle of insonation. Common artifacts are also reviewed. Proper ergonomics, scanning techniques, and safety strategies are emphasized for obtaining optimized ultrasound images.