Soft tissue tumors

Jan 9, 2015Download as PPT, PDF10 likes3,717 views

This document lists and defines different types of soft tissue tumors, including benign lipoma and rhabdomyoma tumors as well as malignant liposarcoma and rhabdomyosarcoma tumors which have several sub-types. It also mentions myositis ossificans, which is a non-cancerous tumor-like lesion.

Soft tissue tumors
Lipoma ,liposarcoma
Rhabdomyoma ,
Rhabdomyosarcoma
Myositis ossificans

Rhabdomyosarcoma
1. Embryonal
2. Botryoid
3. Alveolar
4. Pleomorphic

This document discusses soft tissue tumors. It defines soft tissue and describes its composition. It notes that soft tissue tumors can be caused by radiation, burns, trauma, viruses, or genetic syndromes. The document outlines various tumor types including liposarcomas, fibrosarcomas, and malignant fibrous histiocytomas. It describes histologic patterns seen in different tumors and discusses grading systems. Pseudosarcomas like nodular fasciitis are also summarized.

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METHODS: We analyzed data of 806 consecutive GCP (age=57.1±9.5 years; tumor size=5.4±3.1 cm) radically operated (R0) and monitored in 1975-2025 (m=563, f=243; distal gastrectomies (G)=463, proximal (G)=166, total (G)=177, combined G with resection of pancreas, liver, diaphragm, duodenum, colon transversum, jejunum, cholecystectomy, splenectomy=341; T1=242, T2=223, T3=184, T4=157; N0=443, N1=109, N2=254; G1=225, G2=165, G3=416; early GC=168, invasive=638; only surgery=630, adjuvant chemoimmunotherapy-AT=176: 5-FU+thymalin/taktivin). Variables selected for prognosis study were input levels of 45 blood parameters, sex, age, TNMG, cell type, tumor size. Survival curves were estimated by the Kaplan-Meier method. Differences in curves between groups of GCP were evaluated using a log-rank test. Multivariate Cox modeling, clustering, SEPATH, Monte Carlo, bootstrap and neural networks computing were used to determine any significant dependence. RESULTS: Overall life span (LS) was 2146.8±2350.4 days and cumulative 5-year survival (5YS) reached 58.6%, 10 years – 52.5%, 20 years – 40.2%, 30 years – 28%. 322 GCP lived more than 5 years (LS=4337.4±2377.7 days), 172 GCP – more than 10 years (LS=5966.5±2159.7 days). 291 GCP died because of GC (LS=649.9±347.1 days). AT significantly improved 5YS (67.5% vs. 56.9%) (P=0.047 by log-rank test). Cox modeling displayed that 5YS of GCP significantly depended on: phase transition (PT) in terms of synergetics N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G, prothrombin index, residual nitrogen, blood cells subpopulations, age, sex, GC cell dynamics, histology, tumor growth, bilirubin, chlorides, procedure type (P=0.000-0.021). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and healthy cells/CC (rank=1), PT early—invasive cancer (2); erythrocytes/CC (3), PT N0--N12 (4); leucocytes/CC (5), lymphocytes/CC (6), thrombocytes/CC (7), monocytes/CC (8), segmented neutrophils/CC (9), eosinophils/CC (10); stick neutrophils/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0). CONCLUSIONS: 5-year survival of GCP after radical procedures significantly depended on: 1) PT “early-invasive cancer”; 2) PT N0--N12; 3) Cell Ratio Factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) GC cell dynamics; 9) GC characteristics; 10) tumor localization; 11) anthropometric data; 12) surgery type. Optimal diagnosis and treatment strategies for GC are: 1) screening and early detection of GC; 2) availability of experienced abdominal surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunotherapy for GCP with unfavorable prognosis.

HIV AIDS for university students studyingarthurtheophilus56

duce their risk of acquiring HIV.** * **Highly effective when taken consistently.** * **Requires regular HIV testing and medical monitoring.** • **Post-Exposure Prophylaxis (PEP):** * **Antiretroviral medications taken after a potential exposure to HIV to prevent infection.** * **Must be started within 72 hours of exposure.** * **Typically involves a 28-day course of ART.** • **Harm Reduction Strategies:** * **Needle Exchange Programs:** Provide clean needles and syringes to intravenous drug users to reduce the risk of sharing needles and transmitting HIV. * **Opioid Substitution Therapy:** Using medications such as methadone or buprenorphine to treat opioid addiction. • **Education and Awareness:** * **Providing accurate information about HIV transmission, prevention, and treatment.** * **Addressing stigma and discrimination associated with HIV.** **VIII. Global Impact of HIV/AIDS** HIV/AIDS has had a profound impact on global health and development. • **Prevalence:** An estimated 38.4 million people worldwide were living with HIV in 2021. • **New Infections:** Approximately 1.5 million new HIV infections occurred in 2021. • **Deaths:** 650,000 people died from AIDS-related illnesses in 2021. • **Regional Differences:** The burden of HIV/AIDS is disproportionately high in sub-Saharan Africa. • **Impact on Life Expectancy:** HIV/AIDS has significantly reduced life expectancy in many countries. • **Economic Impact:** HIV/AIDS has had a negative impact on economic development, particularly in countries with high prevalence rates. • **Social Impact:** HIV/AIDS has led to stigma, discrimination, and social isolation for affected individuals and communities. **IX. Ongoing Research and Future Directions** Research continues to play a vital role in the fight against HIV/AIDS. • **Cure Research:** Scientists are working to develop a cure for HIV infection, which could involve eliminating the virus from the body or achieving long-term remission without the need for ART. • **Vaccine Development:** Efforts are underway to develop a safe and effective HIV vaccine that could prevent new infections. • **Improved Treatment Strategies:** Researchers are developing new antiretroviral drugs that are more effective, easier to take, and have fewer side effects. • **Prevention Strategies:** Scientists are exploring new prevention strategies, such as long-acting injectable PrEP and broadly neutralizing antibodies. • **Understanding HIV Reservoirs:** Research is focused on understanding HIV reservoirs, which are cells in the body where HIV can hide and persist even during ART. • **Addressing Co-morbidities:** Research is exploring how HIV infection affects other health conditions, such as cardiovascular disease, cancer, and neurological disorders. **X. Conclusion** HIV/AIDS remains a significant global health challenge, but significant progress has been made in recent decad

BIOMECHANICS & KINESIOLOGY OF THEHIP COMPLEX.pptxdrnidhimnd

The cuplike concave socket of the hip joint is called the acetabulum and is located on the lateral aspect of the pelvic bone (innominate or os coxa). Until full ossification of the pelvis occurs between 20 and 25 years of age. The periphery of the acetabulum (lunate surface) is covered with hyaline cartilage. This horseshoe-shaped area of cartilage articulates with the head of the femur and allows for contact stress to be uniformly distributed. The inferior aspect of the lunate surface (the base of the horseshoe) is interrupted by a deep notch called the acetabular notch. The acetabular notch is spanned by a fibrous band, the transverse acetabular ligament, that connects the two ends of the horseshoe. The acetabulum is deepened by the fibrocartilaginous acetabular labrum, which surrounds the periphery of the acetabulum. The acetabular fossa is non-articular; the femoral head does not contact this surface. The acetabular fossa contains fibroelastic fat covered with synovial membrane.

OECD 404 DI.pdf for the dermal irritationmosahibahmad182

Adverse event following immunizations and Vaccine safety surveillance.pptxDr. Koppala R.V.S. Chaitanya

Awake Craniotomy with endoscopic support, guided by intraoperative ultrasound...Dr. Damian Lastra Copello

Awake Craniotomy with endoscopic support, guided by intraoperative ultrasound, Imeka Neuronavigator and MRI for excision of low-grade Astrocytoma in Sharab Hospital. Case Report. Fontes C1; Sama Y2; Sulayman S 3; BaldehS 4; Ceesay A5; Copello DL6 1. Carlos Fontes. Licensed Nurse in Anesthesiology and Resuscitation. Master's Degree in Emergencies, Assistant Professor University of Medical Sciences of Camaguey. Cuba. Anesthesiology Service, Sharab Hospital. Republic of The Gambia. 2. Sama Yamundaw. Nurse Anesthesiologist Nurse. Anesthesiology Service at Sharab Hospital. Republic of The Gambia 3. Sulayman Sima. Sharab Hospital Surgery Service. Republic of The Gambia. 4. Sanna Baldeh. Scrubs Nurse. Sharab Hospital Surgery Service. Republic of The Gambia. 5. 5 Abdoulie Ceesay. Scrubs Nurse. Sharab Hospital Surgery Service. Republic of The Gambia 6. Dr.Damian Lastra Copello. Consultant Neurosurgeon.MD. Emergency and Critical Care Fellowship. Neuro-Oncology and Spine Surgeon, Lecturer, Researcher, Santiago de Cuba Medical Sciences University, Havana University, Cuba. Neurosurgery Service Sharab Hospital. The Gambia. ORCID: 0000-0002-9393-1933 Abstract Low-grade astrocytomas are considered low-grade gliomas. Low-grade gliomas are brain tumors that grow slowly and require specialized care. They are a group of tumors that include: fibrillary astrocytoma, protoplasmic astrocytoma and gemistocytic astrocytoma. They differ from their counterpart high-grade astrocytomas, because they have a better prognosis and longer survival, although each of them is a different disease with a different course and prognosis.As a group, they represent 26.6% of all tumors derived from glial cells in the brain.Separated by age, they represent approximately 15% of intracranial tumors in adults and 25% in children. (1 -8) The age of presentation of these tumors in adults is around the 4th decade of life. The frontal lobe is the most frequent location, followed by the temporal and parietal lobes. Currently, technology has increased the safety of surgical procedures, with the arrival of techniques such as neuronavigation, stereotaxy, transoperative brain mapping, transoperative ultrasound or ultrasonic aspirator; all of them in contemporary times must be used with reasoning for the greater benefit of the patient. A craniotomy is a complex neurological procedure that involves opening the skull, performing the necessary operation, and closing the skull, securing the bone in its original position. (4 -10) Awake craniotomy is mainly used for mapping and resection of lesions in vitally important brain areas where imaging is not sufficiently sensitive. These are most commonly speech and motor areas. In all sedation-anesthesia techniques, the patients are awake and able to speak and/or move during the mapping phase. It is a technique used to improve perioperative outcomes, achieving a faster recovery of the patient with a reduction in the percentage of postoperative complications.

Bill Faloon discusses age-reversal updates at HEALINC 2025maximuspeto

Hyperkalemia - An overview : Causes and managementdramiraaref

Pharmacovigilance aspects : Predictability & Preventability Assessment.pptxDr. Koppala R.V.S. Chaitanya

Methods of Cancer diagnosis in Context of RadiotherapySaikat Roy

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Esophageal Cancer: Artificial Intelligence, Synergetics, Complex System Analy...Oleg Kshivets

We analyzed data of 568 consecutive ECP (age=56.7±9 years; tumor size=5.9±3.5 cm) radically operated (R0) and monitored in 1975-2025 (m=424, f=144; esophagogastrectomies (EG) Garlock=290, EG Lewis=278, combined EG with resection of pancreas, liver, diaphragm, aorta, VCS, colon transversum, lung, trachea, pericardium, splenectomy=174; adenocarcinoma=326, squamous=232, mix=10; T1=133, T2=121, T3=186, T4=128; N0=288, N1=71, N2=209; G1=161, G2=143, G3=264; early EC=114, invasive=454; only surgery=431, adjuvant chemoimmunoradiotherapy-AT=137: 5-FU+thymalin/taktivin+radiotherapy 45-50Gy). Multivariate Cox modeling, clustering, SEPATH, Monte Carlo, bootstrap and neural networks computing were used to determine any significant dependence. RESULTS: Overall life span (LS) was 1906.3±2278.4 days and cumulative 5-year survival (5YS) reached 53%, 10 years – 46.4%, 20 years – 33.4%, 30 years – 27.5%. 194 ECP lived more than 5 years (LS=4300.8±2503.5 days), 105 ECP – more than 10 years (LS=5860.8±2469.2 days). 232 ECP died because of EC (LS=628.8±321.8 days). AT significantly improved 5YS (60.3% vs. 43.1%) (P=0.007 by log-rank test). 5YS of ECP of upper/3 was significantly better than others (65.3% vs.50.3%) (P=0.003). Cox modeling displayed that 5YS of ECP significantly depended on: phase transition (PT) N0—N12 in terms of synergetics, blood cell subpopulation, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), EC cell dynamics, T, G, histology, age, localization, prothrombin index, coagulation time, residual nitrogen, chlorides (P=0.000-0.047). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and healthy cells/CC (rank=1), erythrocytes/CC (2), PT N0—N12 (3), PT early-invasive EC (4), thrombocytes/CC (5); segmented neutrophils/CC (6), lymphocytes/CC (7), eosinophils/CC (8), stick neutrophils/CC (9), leucocytes/CC (10), monocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0). CONCLUSIONS: 5-year survival of ECP after radical procedures significantly depended on: 1) PT “early-invasive cancer”; 2) PT N0--N12; 3) Cell Ratio Factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) EC cell dynamics; 9) EC characteristics; 10) tumor localization; 11) anthropometric data; 12) surgery type. Optimal diagnosis and treatment strategies for EC are: 1) screening and early detection of EC; 2) availability of sufficient quantity of very experienced thoracoabdominal surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for ECP with unfavorable prognosis.

Normal distribution and Z score Test for post graduate and undergraduate stu...Tauseef Jawaid

Lecture chi squire. For Postgraduate and UndergraduateTauseef Jawaid

2025-ADA-SOC-Slide-Deck-all-recommendations-FINAL-12-9-24.pptxTanja Milenković

The joint EASD (European Association for the Study of Diabetes) and ADA (American Diabetes Association) Consensus Report on the management of hyperglycaemia in type 2 diabetes serves as a comprehensive, evidence-based guide to help clinicians provide patient-centered care. Updated regularly, the report reflects evolving scientific evidence, advances in pharmacological therapies, and a growing emphasis on individualization of treatment. The 2022 edition emphasizes a holistic approach to managing type 2 diabetes, integrating lifestyle interventions, glucose-lowering medications, cardiovascular and renal risk reduction, and patient preferences. The report moves beyond strict glycemic targets alone and promotes the consideration of comorbid conditions—such as cardiovascular disease, chronic kidney disease (CKD), and obesity—when choosing therapies. The document highlights the importance of metformin as a foundational therapy but recommends early use of SGLT2 inhibitors or GLP-1 receptor agonists in patients with established cardiovascular or renal disease, regardless of HbA1c levels. These classes offer benefits beyond glucose control, including heart failure risk reduction and kidney protection. A key feature of the consensus is its endorsement of shared decision-making, taking into account patient goals, preferences, access, and affordability. The report also discusses the role of digital health tools, continuous glucose monitoring, and team-based care in improving outcomes. Glycemic targets are individualized, typically aiming for an HbA1c of <7%, but allowing flexibility based on age, duration of diabetes, comorbidities, and risk of hypoglycemia. The report also underscores the need for regular reassessment, treatment intensification when needed, and ongoing patient education. Overall, the EASD-ADA consensus provides a dynamic framework that supports a multifaceted, patient-centric approach to type 2 diabetes care, aiming to reduce complications, improve quality of life, and promote long-term health outcomes.

LDMMIA Reiki Yoga S4 Bonus S2 Clearing ChiLDM Mia eStudios

A 4TH FREE WORKSHOP/ BONUS SESSION 2 Reiki Yoga “Clearing” Our Sessions 1-3 are available for download notes. Thx for Reading. https://ko-fi.com/ldmmia Celebrating my 49th Bday. A Taurus Sun, Born early May 3rd, “76”. Also A Gemini Moon/Rising. I follow Both signs. Welcome to the 2nd Bonus Session. Beyond Basics - Good Vibes Only: —Review - Good Vibes Only: — For me, within both Reiki and Yoga sessions the essentials boost the energy. Energy can also be called Vibrations and Frequency. So many coaches are specializing within Frequency topics. They can coach entire themes using Frequency success stories. This shows how little we think of energy? We need our coaches to boost our wisdom? To boost the vibes? For Reiki & Yoga Therapy, using ‘Props’ can assist, protect, and heal energies - faster/better. Let’s Explore more. (See Presentation for all sections, THX) Clear Your Energy Pt 1…(See Presentation) Clear Your Energy - Pt 2 I know we operate busy schedules. Sometimes I will yoga stretch, do warm ups, Fuse Qigong, and clear my chakras. It can be therapy or for energy boosts. So many things within our activities will leave behind energy. This can be positive or negative. We assume these energies naturally drop off. But, not always the case. Some energies latch on longterm. This all depends on your moods, emotions, and lifestyle. Hope it makes sense. We have to monitor our energy intake/out-take. Repost: Taking breaks, pausing, relaxing, are common things ppl struggle with. Including at times, myself. Reiki requires chill hours or meditations. We often believe our schedules are badges to display for social/approval? This is a generational society belief. It takes courage to bold/quietly declare - the opposite. (Old Matrix Systems) Energy Monitoring-The Media/News A Perm bonus section I wanted to keep. This is about The media and news. Now, I understand it’s hard to avoid all news. Especially when we need our global, local, weather, and economic updates. Some news are important while others are extremely negative. Anything hosting bad vibes can be draining. I have seen this occur within distant/visual updates like news or gossip. We have to keep what we need. Then leave behind what we don’t. The intuitive coaching/Tarot rules. There’s a lot going on for every country. So now is the time to practice calming methods for daily life or emergencies. (See Presentation for all, new topics, THX) To Donate/Tip/Love Offerings: ♥¸.•♥ ♥¸.•♥ - https://ko-fi.com/ldmmia - CashApp: $ldmmia2 or https://ldmchapels.weebly.com Public Social: https://www.instagram.com/chelleofsl/ https://x.com/OnlineDrLeZ

Basic of ECG & Cardiac monitoring for Health Professionals.pptxAsokan R

Severity and seriousness assessment: Pharmacovigilance aspects.Dr. Koppala R.V.S. Chaitanya

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Artificial Intelligence in Oncology: Transforming Cancer CarepptxNEIGRIHMS, SHILLONG

Artificial Intelligence (AI) is transforming oncology by enabling faster, more accurate, and personalized cancer care. AI uses technologies like machine learning (ML), deep learning (DL), and natural language processing (NLP) to analyze complex medical data, helping doctors make better decisions at every stage of cancer care. Key Applications of AI in Oncology: Cancer Detection & Diagnosis: AI analyzes radiology (CT, MRI, mammography) and pathology images to detect tumors early and accurately. Tools like PathAI, Aidoc, and DeepMind are used in clinical imaging. Precision Medicine & Genomics: AI interprets genetic mutations to match patients with targeted therapies. Platforms like Tempus and OncoKB support personalized cancer treatment. Radiation Oncology: AI automates contouring, treatment planning, and dose optimization. Reduces planning time and improves consistency in radiation delivery. Drug Discovery & Clinical Trials: AI helps discover new cancer drugs and match patients to trials. Companies like BenevolentAI and Insilico Medicine lead this space. Prognostics & Monitoring: AI predicts survival, recurrence, and side effects using patient data. Wearables and mobile apps track symptoms and alert doctors in real time. Benefits of AI in Oncology: Early and accurate diagnosis Faster workflows and reduced workload Personalized treatments Improved patient outcomes Challenges: Data privacy and bias Lack of clinical validation Interpretability of AI decisions Integration into hospital systems Conclusion: AI is not replacing oncologists but empowering them with better tools to diagnose, plan, and treat cancer more effectively. With ongoing research and responsible use, AI will play a crucial role in the future of oncology.