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| label / ast | label / ast |
| | | The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis |
| description / ar | description / ar |
| | | مقالة علمية (نشرت في مايو 2007) |
| description / ast | description / ast |
| | | artículu científicu espublizáu en 2007 |
| description / uk | description / uk |
| | | наукова стаття, опублікована в травні 2007 |
| description / hy | description / hy |
| | | 2007 թվականի մայիսին հրատարակված գիտական հոդված |
| description / hyw | description / hyw |
| | | 2007 թուականի Մայիսին հրատարակուած գիտական յօդուած |
| description / de | description / de |
| | | im Mai 2007 veröffentlichter wissenschaftlicher Artikel |
| description / fr | description / fr |
| | | article scientifique publié en 2007 |
| Property / PubMed publication ID: 17437992 / reference |
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| Property / PubMed publication ID: 17437992 / reference | |
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| Property / author name string | |
| Ralph J. DeBerardinis
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| Property / author name string: Ralph J. DeBerardinis / rank | |
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| Property / author name string: Ralph J. DeBerardinis / qualifier | |
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| Property / author name string: Ralph J. DeBerardinis / reference | |
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| Property / author name string | |
| Craig B. Thompson
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| Property / author name string: Craig B. Thompson / rank | |
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| Property / author name string: Craig B. Thompson / qualifier | |
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| Property / author name string: Craig B. Thompson / reference | |
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| Property / DOI: 10.1101/GAD.1529107 / reference |
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| Property / DOI: 10.1101/GAD.1529107 / reference | |
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| Property / PMC publication ID: 1855230 / reference |
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| Property / cites work: HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption / reference |
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| Property / cites work: HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption / reference | |
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| Property / cites work: HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia / reference |
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| Property / cites work: HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia / reference | |
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| Property / cites work: Differential gene up-regulation by hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha in HEK293T cells / reference |
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| Property / cites work: Differential gene up-regulation by hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha in HEK293T cells / reference | |
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| Property / cites work: Growth factor regulation of autophagy and cell survival in the absence of apoptosis / reference |
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| Property / cites work: Growth factor regulation of autophagy and cell survival in the absence of apoptosis / reference | |
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| Property / cites work: Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase / reference |
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| Property / cites work: Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase / reference | |
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| Property / cites work: Ras induction of superoxide activates ERK-dependent angiogenic transcription factor HIF-1alpha and VEGF-A expression in shock wave-stimulated osteoblasts / reference |
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| Property / cites work: Ras induction of superoxide activates ERK-dependent angiogenic transcription factor HIF-1alpha and VEGF-A expression in shock wave-stimulated osteoblasts / reference | |
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| Property / cites work: Targeting HIF-1 for cancer therapy / reference |
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| Property / cites work: Targeting HIF-1 for cancer therapy / reference | |
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| Property / cites work: HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation / reference |
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| Property / cites work: Growth factors can influence cell growth and survival through effects on glucose metabolism / rank |
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| Property / cites work: Growth factors can influence cell growth and survival through effects on glucose metabolism / reference |
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| Property / cites work: Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation / reference |
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| Property / cites work: Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases / rank |
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| Property / cites work: Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases / reference |
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| Property / cites work: The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis / rank |
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| Property / cites work: The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis / reference |
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| Property / cites work: Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis / rank |
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| Property / cites work: Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis / reference |
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| Property / cites work: HIF-1 alpha is required for solid tumor formation and embryonic vascularization. / rank |
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| Property / cites work: HIF-1 alpha is required for solid tumor formation and embryonic vascularization. / reference |
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| Property / cites work: Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha / rank |
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| Property / cites work: Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha / reference |
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| Property / cites work: HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability / rank |
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| Property / cites work: HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability / reference |
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| Property / cites work: Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing / rank |
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| Property / cites work: Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing / reference |
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| Property / cites work: Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance / rank |
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| Property / cites work: Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance / reference |
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| Property / cites work: Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation / rank |
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| Property / cites work: Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation / reference |
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| Property / cites work: Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics / rank |
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| Property / cites work: Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics / reference |
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| Property / cites work: HIF1alpha delays premature senescence through the activation of MIF. / rank |
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| Property / cites work: HIF1alpha delays premature senescence through the activation of MIF. / reference |
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| Property / cites work: Phosphatidylinositol 3-kinase-dependent modulation of carnitine palmitoyltransferase 1A expression regulates lipid metabolism during hematopoietic cell growth / rank |
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| Property / cites work: Phosphatidylinositol 3-kinase-dependent modulation of carnitine palmitoyltransferase 1A expression regulates lipid metabolism during hematopoietic cell growth / reference |
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| Property / cites work: Hypoxia signalling in cancer and approaches to enforce tumour regression / rank |
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| Property / cites work: Hypoxia signalling in cancer and approaches to enforce tumour regression / reference |
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| Property / cites work: ATP citrate lyase inhibition can suppress tumor cell growth / rank |
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| Property / cites work: ATP citrate lyase inhibition can suppress tumor cell growth / reference |
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| Property / cites work: Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1. / rank |
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| Property / cites work: Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1. / reference |
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| Property / cites work: Manganese superoxide dismutase suppresses hypoxic induction of hypoxia-inducible factor-1alpha and vascular endothelial growth factor / rank |
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| Property / cites work: Manganese superoxide dismutase suppresses hypoxic induction of hypoxia-inducible factor-1alpha and vascular endothelial growth factor / reference |
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| Property / cites work: Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation / rank |
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| Property / cites work: Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation / reference |
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| Property / cites work: Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1alpha, causing glycolysis shutdown and cell death / rank |
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| Property / cites work: Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1alpha, causing glycolysis shutdown and cell death / reference |
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| Property / cites work: Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand / rank |
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| Property / cites work: Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand / reference |
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| Property / cites work: HIF-1alpha induces cell cycle arrest by functionally counteracting Myc. / rank |
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| Property / cites work: HIF-1alpha induces cell cycle arrest by functionally counteracting Myc. / reference |
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| Property / cites work: Growth factor-mediated induction of HDM2 positively regulates hypoxia-inducible factor 1alpha expression / rank |
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| Property / cites work: Growth factor-mediated induction of HDM2 positively regulates hypoxia-inducible factor 1alpha expression / reference |
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| Property / cites work: Nitric Oxide Induces Hypoxia-inducible Factor 1 Activation That Is Dependent on MAPK and Phosphatidylinositol 3-Kinase Signaling / rank |
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| Property / cites work: Nitric Oxide Induces Hypoxia-inducible Factor 1 Activation That Is Dependent on MAPK and Phosphatidylinositol 3-Kinase Signaling / reference |
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| Property / cites work: Activated pp60c-Src leads to elevated hypoxia-inducible factor (HIF)-1alpha expression under normoxia / rank |
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| Property / cites work: Activated pp60c-Src leads to elevated hypoxia-inducible factor (HIF)-1alpha expression under normoxia / reference |
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| Property / cites work: The CD28 signaling pathway regulates glucose metabolism / rank |
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| Property / cites work: The CD28 signaling pathway regulates glucose metabolism / reference |
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| Property / cites work: Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription / rank |
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| Property / cites work: Phosphatidylinositol 3-kinase/Akt signaling is neither required for hypoxic stabilization of HIF-1 alpha nor sufficient for HIF-1-dependent target gene transcription / reference |
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| Property / cites work: Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1. / rank |
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| Property / cites work: Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1. / reference |
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| Property / cites work: HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression / rank |
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| Property / cites work: HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression / reference |
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| Property / cites work: Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells. / rank |
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| Property / cites work: Transcription factor HIF-1 is a necessary mediator of the pasteur effect in mammalian cells. / reference |
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| Property / cites work: In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability / rank |
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| Property / cites work: In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability / reference |
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| Property / cites work: Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth. / rank |
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| Property / cites work: Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth. / reference |
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| Property / cites work: Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells / rank |
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| Property / cites work: Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells / reference |
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| Property / cites work: V-SRC induces expression of hypoxia-inducible factor 1 (HIF-1) and transcription of genes encoding vascular endothelial growth factor and enolase 1: involvement of HIF-1 in tumor progression. / rank |
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| Property / cites work: V-SRC induces expression of hypoxia-inducible factor 1 (HIF-1) and transcription of genes encoding vascular endothelial growth factor and enolase 1: involvement of HIF-1 in tumor progression. / reference |
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| Property / cites work: A hypoxia-independent hypoxia-inducible factor-1 activation pathway induced by phosphatidylinositol-3 kinase/Akt in HER2 overexpressing cells / rank |
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| Property / cites work: Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation / rank |
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| Property / cites work: Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway / rank |
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| Property / cites work: Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway / reference |
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| Property / cites work: p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1. / rank |
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| Property / cites work: p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1. / reference |
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| Property / cites work: Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1 / rank |
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| Property / cites work: Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells / rank |
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| Property / OpenCitations bibliographic resource ID |
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| Property / OpenCitations bibliographic resource ID: 1370378 / rank |
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| Property / OpenCitations bibliographic resource ID: 1370378 / reference |
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| Property / ResearchGate publication ID |
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| Property / ResearchGate publication ID: 6390553 / rank |
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| Property / main subject: Interleukin 3 / rank |
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| Property / main subject: Interleukin 3 / reference |
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| Property / main subject |
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| Property / main subject: Hypoxia inducible factor 1, alpha subunit / rank |
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| Property / main subject: Hypoxia inducible factor 1, alpha subunit / reference |
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| Property / author |
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| Property / author: Ralph J DeBerardinis / rank |
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| Property / author: Ralph J DeBerardinis / qualifier |
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| Property / author: Ralph J DeBerardinis / qualifier |
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| Property / author: Ralph J DeBerardinis / reference |
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| Property / author |
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| Property / author: Craig B. Thompson / rank |
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| Property / author: Craig B. Thompson / qualifier |
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| Property / author: Craig B. Thompson / qualifier |
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| Property / author: Craig B. Thompson / reference |
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