Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis (Q28551227)

2

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Benoit Viollet

object named as

Benoit Viollet

7

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author name string

Takla Griss

1

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Robert Egnatchik

3

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Jocelyn Chen

4

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Eric H Ma

5

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Ralph J DeBerardinis

8

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Russell G Jones

Metformin as an adjuvant drug against pediatric sarcomas: hypoxia limits therapeutic effects of the drug

9

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language of work or name

English

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publication date

December 2015

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published in

PLOS Biology

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volume

13

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issue

12

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page(s)

e1002309

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cites work

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Hypoxic regulation of glutamine metabolism through HIF1 and SIAH2 supports lipid synthesis that is necessary for tumor growth

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LKB1 is a central regulator of tumor initiation and pro-growth metabolism in ErbB2-mediated breast cancer

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Phenformin enhances the therapeutic benefit of BRAF(V600E) inhibition in melanoma

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Metformin decreases glucose oxidation and increases the dependency of prostate cancer cells on reductive glutamine metabolism.

29 September 2017

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