Pages that link to "Q34571293"
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The following pages link to Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer. (Q34571293):
Displaying 50 items.
- Approaches of targeting Rho GTPases in cancer drug discovery (Q26851300) (← links)
- Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease (Q26853181) (← links)
- Norbin Stimulates the Catalytic Activity and Plasma Membrane Localization of the Guanine-Nucleotide Exchange Factor P-Rex1. (Q27312178) (← links)
- P-Rex1 cooperates with PDGFRβ to drive cellular migration in 3D microenvironments (Q27320507) (← links)
- Regulation and function of P-Rex family Rac-GEFs (Q28087472) (← links)
- A synthetic biology approach reveals a CXCR4-G13-Rho signaling axis driving transendothelial migration of metastatic breast cancer cells (Q30524460) (← links)
- Nodal signaling regulates endodermal cell motility and actin dynamics via Rac1 and Prex1 (Q30524670) (← links)
- Transforming potential and matrix stiffness co-regulate confinement sensitivity of tumor cell migration (Q30543780) (← links)
- Preclinical development of novel Rac1-GEF signaling inhibitors using a rational design approach in highly aggressive breast cancer cell lines. (Q31140123) (← links)
- Identification and characterization of cancer mutations in Japanese lung adenocarcinoma without sequencing of normal tissue counterparts (Q31140151) (← links)
- Therapeutic sensitivity to Rac GTPase inhibition requires consequential suppression of mTORC1, AKT, and MEK signaling in breast cancer (Q33591690) (← links)
- Novel insights into G protein and G protein-coupled receptor signaling in cancer (Q33612895) (← links)
- PI(3,4)P2 plays critical roles in the regulation of focal adhesion dynamics of MDA-MB-231 breast cancer cells (Q33738762) (← links)
- BreakTrans: uncovering the genomic architecture of gene fusions (Q33744985) (← links)
- P-Rex1 Expression in Invasive Breast Cancer in relation to Receptor Status and Distant Metastatic Site. (Q33862302) (← links)
- Non-small cell lung carcinoma cell motility, rac activation and metastatic dissemination are mediated by protein kinase C epsilon (Q34181904) (← links)
- P-Rex1 is required for efficient melanoblast migration and melanoma metastasis (Q34235334) (← links)
- The Rac Inhibitor EHop-016 Inhibits Mammary Tumor Growth and Metastasis in a Nude Mouse Model (Q34478364) (← links)
- Subtype-specific overexpression of the Rac-GEF P-REX1 in breast cancer is associated with promoter hypomethylation. (Q35000289) (← links)
- Epigenetic regulation of phosphatidylinositol 3,4,5-triphosphate-dependent Rac exchanger 1 gene expression in prostate cancer cells (Q35110991) (← links)
- RASAL2 activates RAC1 to promote triple-negative breast cancer progression (Q35145423) (← links)
- Characterization of the Rac guanine nucleotide exchange factor P-Rex1 in platelets (Q35231317) (← links)
- P-REX1 creates a positive feedback loop to activate growth factor receptor, PI3K/AKT and MEK/ERK signaling in breast cancer. (Q35288044) (← links)
- Optimizing sparse sequencing of single cells for highly multiplex copy number profiling (Q35561968) (← links)
- SDF-1/CXCL12 induces directional cell migration and spontaneous metastasis via a CXCR4/Gαi/mTORC1 axis (Q35576488) (← links)
- Role for the guanine nucleotide exchange factor phosphatidylinositol-3,4,5-trisphosphate-dependent rac exchanger 1 in platelet secretion and aggregation (Q35785016) (← links)
- Rac signaling in breast cancer: a tale of GEFs and GAPs. (Q35854151) (← links)
- Characterization of EHop-016, novel small molecule inhibitor of Rac GTPase (Q35921528) (← links)
- The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1·Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1·Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells (Q35978229) (← links)
- Determinant role for the gep oncogenes, Gα12/13, in ovarian cancer cell proliferation and xenograft tumor growth. (Q36075415) (← links)
- Regulation of the mTOR-Rac1 axis in platelet function (Q36100859) (← links)
- Targeting of Rac GTPases blocks the spread of intact human breast cancer. (Q36234042) (← links)
- Loss of the E3 ubiquitin ligase HACE1 results in enhanced Rac1 signaling contributing to breast cancer progression (Q36250061) (← links)
- p21-activated Kinases (PAKs) Mediate the Phosphorylation of PREX2 Protein to Initiate Feedback Inhibition of Rac1 GTPase (Q36323481) (← links)
- Minireview: Mouse Models of Rho GTPase Function in Mammary Gland Development, Tumorigenesis, and Metastasis (Q36632432) (← links)
- Infectivity and insertional mutagenesis of endogenous retrovirus in autoimmune NZB and B/W mice. (Q36725555) (← links)
- Protein Kinase A (PKA) Type I Interacts with P-Rex1, a Rac Guanine Nucleotide Exchange Factor: EFFECT ON PKA LOCALIZATION AND P-Rex1 SIGNALING (Q36744738) (← links)
- Ras-related C3 botulinum toxin substrate 1 (RAC1) regulates glucose-stimulated insulin secretion via modulation of F-actin (Q36755888) (← links)
- Cucurbitacin I inhibits Rac1 activation in breast cancer cells by a reactive oxygen species-mediated mechanism and independently of Janus tyrosine kinase 2 and P-Rex1. (Q36776754) (← links)
- Rac-specific guanine nucleotide exchange factor DOCK1 is a critical regulator of HER2-mediated breast cancer metastasis (Q36820193) (← links)
- Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3. (Q36880840) (← links)
- Identification of P-Rex1 as an anti-inflammatory and anti-fibrogenic target for pulmonary fibrosis (Q36897675) (← links)
- A critical role for phosphatidylinositol (3,4,5)-trisphosphate-dependent Rac exchanger 1 in endothelial junction disruption and vascular hyperpermeability (Q36917040) (← links)
- PTEN inhibits PREX2-catalyzed activation of RAC1 to restrain tumor cell invasion (Q36921660) (← links)
- Ubiquitylation of phosphatidylinositol 4-phosphate 5-kinase type I γ by HECTD1 regulates focal adhesion dynamics and cell migration (Q36943307) (← links)
- Timing is everything: Rac1 controls Net1A localization to regulate cell adhesion (Q37085734) (← links)
- How integrins control breast biology (Q37254238) (← links)
- PI3K regulates MEK/ERK signaling in breast cancer via the Rac-GEF, P-Rex1. (Q37421358) (← links)
- Characterization of a P-Rex1 gene signature in breast cancer cells (Q37588287) (← links)
- Identification of genes associated with tongue cancer in patients with a history of tobacco and/or alcohol use. (Q37700692) (← links)