(S)-(−)-colchicine (Q326224)

http://www.cdc.gov/niosh/ershdb/emergencyresponsecard_29750016.html

science

1 reference

http://www.cdc.gov/niosh/ershdb/emergencyresponsecard_29750016.html

1 reference

Colchicine (English)

17 November 2015

Colchicin2.svg
366 × 350; 30 KB

0 references

image

Colchicine.png
2,124 × 1,944; 4.82 MB

0 references

mass

399.168188 dalton

1 reference

https://www.cdc.gov/niosh/ershdb/emergencyresponsecard_29750016.html

Colchine (English)

4 October 2016

1 reference

color

yellow

2 references

http://www.cdc.gov/niosh/ershdb/emergencyresponsecard_29750016.html

CRC Handbook of Chemistry and Physics (97th edition)

3-126

yellow-green

1 reference

http://www.cdc.gov/niosh/ershdb/emergencyresponsecard_29750016.html

made from material

Colchicum autumnale

1 reference

http://www.cdc.gov/niosh/ershdb/emergencyresponsecard_29750016.html

Gloriosa superba

1 reference

http://www.cdc.gov/niosh/ershdb/emergencyresponsecard_29750016.html

stereoisomer of

(R)-colchicine

2 references

based on heuristic

inferred from InChIKey

based on heuristic

inferred from InChI

chemical formula

C₂₂H₂₅NO₆

1 reference

Colchine (English)

4 October 2016

CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC

1 reference

Colchine (English)

4 October 2016

CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC

0 references

melting point

156 degree Celsius

1 reference

CRC Handbook of Chemistry and Physics (97th edition)

CRC Handbook of Chemistry and Physics (97th edition)

3-126

solubility

42 gram per kilogram of solvent

20 degree Celsius

1 reference

5-145

unknown value

temperature

unknown value

solvent

ethanol

descriptive solubility

freely soluble

1 reference

CRC Handbook of Chemistry and Physics (97th edition)

3-126

pKa

12.36

temperature

20 degree Celsius

1 reference

CRC Handbook of Chemistry and Physics (97th edition)

safety classification and labelling

5-90

NFPA 704: Standard System for the Identification of the Hazards of Materials for Emergency Response

3

1

0

no value

1 reference

https://www.cdc.gov/niosh/ershdb/emergencyresponsecard_29750016.html

5 May 2018

defined daily dose

1 milligram

route of administration

oral administration

1 reference

https://www.whocc.no/atc_ddd_index/?code=M04AC01

1 milligram

route of administration

parenteral route of administration

1 reference

https://www.whocc.no/atc_ddd_index/?code=M04AC01

2 references

24 September 2016

http://identifiers.org/wikipathways/WP2289_r78511

Colchicum robustum

4 references

2,10-Didemethylcolchicine ? A new alkaloid from Merendera robusta

Alkaloids of Merendera iolantae

Substances from the plants of the sub-family Wurmbaeoideae and their derivatives. LIX. Isolation of alkaloids from some plants of the sub-family Wurmbaeoideae

Robustamine ? A new homoproapophine base fromMerendera robusta

Colchicum kesselringii

1 reference

Alkaloids of the corms of Colchicum kesselringii

Colchicum kurdicum

1 reference

Colchicum manissadjianii

1 reference

Colchicum soboliferum

1 reference

Sandersonia aurantiaca

2 references

Isolation of Colchicine from Sandersonia aurantiaca and Gloriosa superba. Variation in the Alkaloid Levels of Plants Grown in vivo

Metacolchicine, a New Colchicinoid from Sandersonia aurantiaca

Alstroemeria aurea

1 reference

Substances from the plants of the sub-family Wurmbaeoideae and their derivatives. LIX. Isolation of alkaloids from some plants of the sub-family Wurmbaeoideae

Calochortus venustus

1 reference

Substances from the plants of the sub-family Wurmbaeoideae and their derivatives. LIX. Isolation of alkaloids from some plants of the sub-family Wurmbaeoideae

Camptorrhiza strumosa

1 reference

Substances from the plants of the sub-family Wurmbaeoideae and their derivatives. LIX. Isolation of alkaloids from some plants of the sub-family Wurmbaeoideae

Colchicum arenarium

3 references

ALKALOIDS FROM COLCHICUM ARENARIUM

Substances from the plants of the subfamily Wurmbaeoideae and their derivatives. LXXIV. Re-examination of some minor alkaloids of unknown constitution isolated from Colchicum autumnale L.

Substanzen der herbstzeitlose und ihre derivate XXXIII. Isolierung weiterer substanzen aus den samen der herbstzeitlose (Colchicum autumnale L.)

Colchicum autumnale

13 references

Formation of alkaloids in suspension-cultured Colchicum autumnale

Colchicine precursors and the formation of alkaloids in suspension-cultured Colchicum autumnale

Incorporation of phenethylisoquinolines into colchicine in isolated seeds of Colchicum autumnale

The Biosynthesis of the phenethylisoquinoline alkaloid colchicine. Early and intermediate stages

Colchicine is formed by para-para phenol coupling from autumnaline

Biosynthesis. Part 27.1,2 Colchicine: studies of the phenolic oxidative coupling and ring-expansion processes based on incorporation of multiply labelled 1-phenethylisoquinolines

Biosynthesis. Part 28.1,2 Colchicine: definition of intermediates between O-methylandrocymbine and colchicine and studies on speciosine

Biosynthesis. Part 29.1 Colchicine: studies on the ring expansion step focusing on the fate of the hydrogens at C-3 of autumnaline

Biosynthesis. Part 30.1 Colchicine: studies on the ring expansion step focusing on the fate of the hydrogens at C-4 of autumnaline

Biosynthesis. Part 26. Synthetic studies on structural modification of late biosynthetic precursors for colchicine

Colchicoside in Colchicum autumnale bulbs.

Alkaloids in Meadow Saffron,Colchicum autumnaleL.

Supercritical carbon dioxide extraction of colchicine and related alkaloids from seeds of Colchicum autumnale L.

Colchicum bornmuelleri

2 references

Incorporation of phenethylisoquinolines into colchicine in isolated seeds of Colchicum autumnale

Colchicum kotschyi

1 reference

Colchicum laetum

1 reference

Alkaloids of the corms of Colchicum laetum

Colchicum luteum

1 reference

Powder Microscopy and Chemical Evaluation ofColchicum luteumCorm

Colchicum neapolitanum

1 reference

Incorporation of phenethylisoquinolines into colchicine in isolated seeds of Colchicum autumnale

Colchicum ritchii

2 references

Five New Alkaloids from Colchicum ritchii

Substances from the plants of the sub-family Wurmbaeoideae and their derivatives. LIX. Isolation of alkaloids from some plants of the sub-family Wurmbaeoideae

Colchicum turcicum

1 reference

Gagea lutea

1 reference

Substances from the plants of the sub-family Wurmbaeoideae and their derivatives. LIX. Isolation of alkaloids from some plants of the sub-family Wurmbaeoideae

Ginkgo biloba

1 reference

Evaluation of commercial Ginkgo biloba dietary supplements for the presence of colchicine by high-performance liquid chromatography

Gloriosa superba

4 references

Isolation of Colchicine from Sandersonia aurantiaca and Gloriosa superba. Variation in the Alkaloid Levels of Plants Grown in vivo

Polymorphism in Gloriosa superba

1,2-Didemethylcolchicine: A New Alkaloid from Gloriosa superba

Alkaloids of Gloriosa superba L.

Iphigenia oliveri

1 reference

Substances from the plants of the sub-family Wurmbaeoideae and their derivatives. LIX. Isolation of alkaloids from some plants of the sub-family Wurmbaeoideae

Iphigenia indica

1 reference

Substances from the plants of the sub-family Wurmbaeoideae and their derivatives. LIX. Isolation of alkaloids from some plants of the sub-family Wurmbaeoideae

Iphigenia pallida

1 reference

Substances from the plants of the sub-family Wurmbaeoideae and their derivatives. LIX. Isolation of alkaloids from some plants of the sub-family Wurmbaeoideae

Colchicum montanum

1 reference

Substances from the plants of the sub-family Wurmbaeoideae and their derivatives. LIX. Isolation of alkaloids from some plants of the sub-family Wurmbaeoideae

Colchicum raddeanum

3 references

A study of the biosynthesis of colchicine and merenderine in Merendera raddeana

N-oxides of homoaporphine alkaloids from Merendera raddeana

Alkaloid specioseine from Colchicum speciosum

Wurmbea deserticola

1 reference

Alkaloids and phenolics of Wurmbea and Burchardia species

Wurmbea dioica

1 reference

Alkaloids and phenolics of Wurmbea and Burchardia species

Wurmbea inframediana

1 reference

Alkaloids and phenolics of Wurmbea and Burchardia species

Wurmbea tenella

1 reference

Alkaloids and phenolics of Wurmbea and Burchardia species

Colchicum crocifolium

1 reference

Colchicinoids from Colchicum crocifolium Boiss. (Colchicaceae).

Colchicum bivonae

1 reference

Isolation and identification of alkaloids from seeds of Colchicum latifolium s. s.

Schelhammera multiflora

1 reference

The presence of colchicine alkaloids inKreysigia multiflora reichb

Colchicum szovitsii

2 references

O-methylkreysigine fromColchicum szovitsii

Alkaloids ofColchicum szovitsii. Structure of szovitsamine

Merendera sobolifera

1 reference

Colchicum schimperi

1 reference

Substances from the plants of the subfamily Wurmbaeoideae and their derivatives. LIII. Chemical investigation of Colchicum cornigerum (SWEINF.) TÄCKH. et DRAR.

Humulus lupulus

1 reference

In vitro tetraploid induction and generation of tetraploids from mixoploids in hop (Humulus lupulus L.)

Strychnos spinosa

1 reference

Antitrypanosomal activity of triterpenoids and sterols from the leaves of Strychnos spinosa and related compounds

Colchicum speciosum

3 references

Incorporation of phenethylisoquinolines into colchicine in isolated seeds of Colchicum autumnale

Mass transfer during the extraction of alkaloids from bulbs of meadow magnificent (Colchicinum spaciosum stev.)

Colchicum trigynum

1 reference

Alkaloids of Merendera trigina structure of trigamine

Bulbocodium vernum

1 reference

Substances from the plants of the sub-family Wurmbaeoideae and their derivatives. LIX. Isolation of alkaloids from some plants of the sub-family Wurmbaeoideae

Penicillium

1 reference

Meroterpenoid and diphenyl ether derivatives from Penicillium sp. MA-37, a fungus isolated from marine mangrove rhizospheric soil.

Colchicum bulbocodium

1 reference

Substances from the plants of the sub-family Wurmbaeoideae and their derivatives. LIX. Isolation of alkaloids from some plants of the sub-family Wurmbaeoideae

medical condition treated

familial Mediterranean fever

1 reference

2 October 2018

gout

1 reference

2 October 2018

Behçet's disease

1 reference

2 October 2018

pericarditis

1 reference

familial Mediterranean fever

2 October 2018

start time

30 July 2009

approved by

Food and Drug Administration

1 reference

Inxight: Drugs Database

2 November 2018

http://www.accessdata.fda.gov/drugsatfda_docs/label/2009/022351lbl.pdf

significant drug interaction

rosuvastatin

1 reference

hypothetically

A reference set of clinically relevant adverse drug-drug interactions

simvastatin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

fluvastatin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

gemfibrozil

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bezafibrate

1 reference

A reference set of clinically relevant adverse drug-drug interactions

ciprofibrate

1 reference

A reference set of clinically relevant adverse drug-drug interactions

atorvastatin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

fenofibrate

1 reference

A reference set of clinically relevant adverse drug-drug interactions

pravastatin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

rosuvastatin

1 reference

hypothetically

A reference set of clinically relevant adverse drug-drug interactions

simvastatin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

fluvastatin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

gemfibrozil

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bezafibrate

1 reference

A reference set of clinically relevant adverse drug-drug interactions

ciprofibrate

1 reference

A reference set of clinically relevant adverse drug-drug interactions

atorvastatin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

fenofibrate

1 reference

A reference set of clinically relevant adverse drug-drug interactions

pravastatin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

physically interacts with

taste receptor type 2

subject has role

agonist

1 reference

The Molecular Receptive Ranges of Human TAS2R Bitter Taste Receptors

pregnancy category

Australian pregnancy category D

1 reference

imported from Wikimedia project

English Wikipedia

US pregnancy category C

1 reference

imported from Wikimedia project

0 references

1 reference

1 reference

Medical Subject Headings

15 March 2018

1 reference

Medical Subject Headings

MeSH descriptor ID

D003078

15 March 2018

developmental toxicant

start time

1 October 1992

1 reference

California Proposition 65 list of chemicals

16 March 2020

https://oehha.ca.gov/chemicals/colchicine

male reproductive toxicant

start time

1 October 1992

1 reference

California Proposition 65 list of chemicals

16 March 2020

https://oehha.ca.gov/chemicals/colchicine

mitotic inhibitor

1 reference

http://www.cdc.gov/niosh/ershdb/emergencyresponsecard_29750016.html

plant hormone

1 reference

http://www.cdc.gov/niosh/ershdb/emergencyresponsecard_29750016.html

Commons category

Colchicine

0 references

Identifiers

InChI

InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1

0 references

1 reference

https://commonchemistry.cas.org/detail?cas_rn=64-86-8

ChEBI release 2020-09-01

1 reference

6 April 2021

1 reference

Colchicine (English)

26 September 2016

1 reference

English

title

Benzo(a)heptalen-9(5H)-one, 7-acetamido-6,7-dihydro-1,2,3,10-tetramethoxy- (English)

4 October 2016

PubChem CID

6167

0 references

Reaxys registry number

2228812

1 reference

colchicine (English)

4 October 2016

mapping relation type

exact match

2 references

ChEBI release 2019-10-02

International Chemical Identifier

InChI

InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1

ChEMBL ID

CHEMBL87

1 reference

CHEMBL87 (English)

4 October 2016

1 reference

COLCHICINE (English)

26 September 2016

2 references

inferred from InChIKey

MSBNK-Athens_Univ-AU117102

1 reference

MassBank accession ID

0 references

MSBNK-Athens_Univ-AU117103

0 references

MSBNK-Athens_Univ-AU117104

0 references

MSBNK-Athens_Univ-AU117105

0 references

MSBNK-Athens_Univ-AU117207

0 references

MSBNK-Athens_Univ-AU117208

0 references

MSBNK-Athens_Univ-AU117209

0 references

MSBNK-Athens_Univ-AU117210

0 references

MSBNK-Athens_Univ-AU117211

0 references

MSBNK-Fiocruz-FIO00425

0 references

MSBNK-Fiocruz-FIO00426

0 references

MSBNK-Fiocruz-FIO00427

0 references

MSBNK-Fiocruz-FIO00428

0 references

MSBNK-Fiocruz-FIO00429

0 references

MSBNK-Waters-WA001567

0 references

MSBNK-Waters-WA001568

0 references

MSBNK-Waters-WA001569

0 references

MSBNK-Waters-WA001570

0 references

MSBNK-Waters-WA001571

0 references

SPLASH

splash10-0udi-0049400000-2a76bd81d41e1bc5925c

0 references

splash10-0gba-0091000000-fb24bc910ffe7bd74811

0 references

splash10-0udi-0000900000-ce5ec1f7b9f845e10782

0 references

splash10-0a4i-0001900000-dd87d7c5c1efbff88578

0 references

splash10-0udi-0000900000-34e9e37282321568b13e

0 references

splash10-001i-0001900000-56fc0f1ad0601ea6295f

0 references

splash10-0zfr-0049400000-687a4992eca4a902fc11

0 references

splash10-03ea-0095000000-a943a6323e48991251b7

0 references

splash10-0gb9-0191000000-98faefcf0de3a4405675

0 references

splash10-0udi-0000900000-d360bbc1ca27b2e657d4

0 references

splash10-0udi-0000900000-44e9ac8566ca5c684603

0 references

splash10-0zfr-0029400000-dc08a845d6fb327eec56

0 references

splash10-03gi-0096000000-1604b0f123208b25b949

0 references

splash10-0gc1-0192000000-dcb2736f710df3f17b01

0 references

splash10-0udi-0195300000-e86188732f86083527ac

0 references

splash10-00di-0003900000-487c63477fe372688360

0 references

NMRShiftDB structure ID

60000009

1 reference

http://www.cdc.gov/niosh/ershdb/emergencyresponsecard_29750016.html

0 references

1 reference

RTECS number

GH0700000

1 reference

http://www.cdc.gov/niosh/ershdb/emergencyresponsecard_29750016.html

0 references

1 reference

Hazardous Substances Data Bank

28 October 2019

COLCHICINE (English)

10 May 2021

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DTXSID20274387

(+/-)-Colchicine

1 reference

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

DTXCID204845

0 references

DTXCID90225866

ECHA Substance Infocard ID

0 references

0 references

0 references

0 references

0 references

100.000.544

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

27 December 2018

Colchicine (English)

CAS no.: 64-86-8 (English)

1 reference

Guide to Pharmacology Ligand ID

English

title

Colchicine (English)

publication date

17 November 2015

2367

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

2367

colchicine (English)

26 September 2016

Colchicine

1 reference

Medical Subject Headings

14 March 2018

0 references

1 reference

26 February 2018

1 reference

Human Metabolome Database ID

HMDB0015466

0 references

0 references

2 references

English

title

Colchicine (English)

4 October 2016

7JX9WZ3SJ5

1 reference

MedlinePlus drug identifier

0 references

1 reference

COLCHICINE (English)

19 January 2016

0 references

1 reference

1 reference

Immune Epitope Database and Analysis Resource

Colchicine (English)

19 January 2016

1 reference

2 September 2019

0 references

1 reference

1 reference

1 reference

California Proposition 65 list of chemicals

12 December 2019

https://oehha.ca.gov/chemicals/colchicine

1 reference

6 April 2020

0 references

electronic Essential Medicines List medicine ID

537

0 references

Encyclopædia Britannica Online ID

science/colchicine

subject named as

colchicine

1 reference

Encyclopædia Britannica Online

Encyclopedia of China (Third Edition) ID

0 references

0 references

1 reference

28 October 2013

0 references

1 reference

9 July 2020

0 references

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

1 reference

imported from Wikimedia project

German Wikipedia

Store medisinske leksikon ID

kolkisin

mapping relation type

related match

subject named as

kolkisin

1 reference

Great Norwegian Encyclopedia

29 May 2020

WikiProjectMed ID

Colchicine

0 references

WordNet 3.1 Synset ID

03070969-n

1 reference