Expression of the E.coli 3-methyladenine DNA glycosylase I gene in mammalian cells reduces the toxic and mutagenic effects of methylating agents (Q41545350)

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scientific article published on December 1, 1992

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English	Expression of the E.coli 3-methyladenine DNA glycosylase I gene in mammalian cells reduces the toxic and mutagenic effects of methylating agents	scientific article published on December 1, 1992

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scholarly article

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Europe PubMed Central

PMC publication ID

3 October 2017

Expression of the E.coli 3-methyladenine DNA glycosylase I gene in mammalian cells reduces the toxic and mutagenic effects of methylating agents (English)

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1425578

25 September 2022

Escherichia coli

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DNA N-glycosylase

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1425578

25 September 2022

1

object named as

A. Klungland

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1425578

25 September 2022

author name string

L. Fairbairn

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1425578

25 September 2022

A. J. Watson

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1425578

25 September 2022

G. P. Margison

4

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25 September 2022

E. Seeberg

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1425578

25 September 2022

language of work or name

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publication date

1 December 1992

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3 October 2017

full work available at URL

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1425578/pdf/?tool=EBI

Portable Document Format

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1425578

25 September 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1425578/?tool=EBI

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1425578

25 September 2022

https://europepmc.org/articles/PMC557018

online access status

content deliverer

Europe PubMed Central

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1425578

25 September 2022

https://europepmc.org/articles/PMC557018?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1425578

25 September 2022

The EMBO Journal

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Europe PubMed Central

PMC publication ID

3 October 2017

11

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Europe PubMed Central

PMC publication ID

3 October 2017

12

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Europe PubMed Central

PMC publication ID

3 October 2017

4439-4444

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

A comprehensive quantitative analysis of methylated and ethylated DNA using high pressure liquid chromatography.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557018

6 June 2018

Two DNA glycosylases in Escherichia coli which release primarily 3-methyladenine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557018

6 June 2018

Adaptation to alkylation resistance involves the induction of a DNA glycosylase

1 reference

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6 June 2018

Induction of a DNA glycosylase for N-methylated purines is part of the adaptive response to alkylating agents

1 reference

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6 June 2018

Enzymatic release of 7-methylguanine from methylated DNA by rodent liver extracts

1 reference

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6 June 2018

Repair of alkylated DNA in Escherichia coli. Methyl group transfer from O6-methylguanine to a protein cysteine residue

1 reference

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6 June 2018

Repair of O6-ethylguanine in DNA by a chromatin fraction from rat liver: transfer of the ethyl group to an acceptor protein.

1 reference

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6 June 2018

Human lymphoblasts contain DNA glycosylase activity excising N-3 and N-7 methyl and ethyl purines but not O6-alkylguanines or 1-alkyladenines

1 reference

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6 June 2018

Inducible repair of O-alkylated DNA pyrimidines in Escherichia coli

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8-Azaguanine resistance in mammalian cells. I. Hypoxanthine-guanine phosphoribosyltransferase

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6 June 2018

Cloning of the E. coli O6-methylguanine and methylphosphotriester methyltransferase gene using a functional DNA repair assay

1 reference

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6 June 2018

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1 reference

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6 June 2018

Purification and characterization of 3-methyladenine DNA glycosylase I from Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=557018

6 June 2018

Amplified expression of the tag+ and alkA+ genes in Escherichia coli: identification of gene products and effects on alkylation resistance

1 reference

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6 June 2018

Reduction of the toxicity and mutagenicity of alkylating agents in mammalian cells harboring the Escherichia coli alkyltransferase gene

1 reference

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6 June 2018

Suppression of human DNA alkylation-repair defects by Escherichia coli DNA-repair genes

1 reference

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6 June 2018

Nucleotide sequence of the tag gene from Escherichia coli

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6 June 2018

Transfection of murine multi-potent haemopoietic stem cells with an E. coli DNA alkyltransferase gene confers resistance to the toxic effects of alkylating agents.

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6 June 2018

Characterisation and nucleotide sequence of ogt, the O6-alkylguanine-DNA-alkyltransferase gene of E. coli

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Increased spontaneous mutation and alkylation sensitivity of Escherichia coli strains lacking the ogt O6-methylguanine DNA repair methyltransferase

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Roles of two types of O6-methylguanine-DNA methyltransferases in DNA repair

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Isolation and structure of a cDNA expressing a mammalian 3-methyladenine-DNA glycosylase

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Two enzymes are required from strand incision in repair of alkylated DNA

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Properties of 3-methyladenine-DNA glycosylase from Escherichia coli

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Biological implications of the instability of the N-glycosidic bone of 3-methyldeoxyadenosine in DNA

1 reference

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Cloning of Escherichia coli genes encoding 3-methyladenine DNA glycosylases I and II

1 reference

https://pubmed.ncbi.nlm.nih.gov/1425578

12 December 2020

based on heuristic

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Mutagenicity of carcinogenic methylating agents is associated with a specific DNA modification

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemical mutagenesis of mammalian cells can be quantified

1 reference

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12 December 2020

based on heuristic

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Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective repair of alkylated DNA by human tumour and SV40-transformed human cell strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/1425578

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Escherichia coli mutants deficient in 3-methyladenine-DNA glycosylase

1 reference

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12 December 2020

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Kinetics of O6-methylguanine repair in human normal and ataxia telangiectasia cell lines and correlation of repair capacity with cellular sensitivity to methylating agents

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/J.1460-2075.1992.TB05544.X

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1425578

25 September 2022

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

3 October 2017

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