cytochrome P450 family 2 subfamily B member 6 (Q5014958)

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mammalian protein found in Homo sapiens

CYP2B6
CYPIIB6
cytochrome P450 2B6
cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6
1,4-cineole 2-exo-monooxygenase
Cytochrome P-450 CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
cytochrome P450 IIB1

Language	Label	Description	Also known as
English	cytochrome P450 family 2 subfamily B member 6	mammalian protein found in Homo sapiens	CYP2B6 CYPIIB6 cytochrome P450 2B6 cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6 1,4-cineole 2-exo-monooxygenase Cytochrome P-450 CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 cytochrome P450 IIB1

Statements

1 reference

13 November 2019

UniProt protein ID

cytochrome P450 superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20813

Cytochrome P450, E-class, group I, CYP2B-like

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20813

cytochrome P450, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

iron ion binding

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

arachidonic acid epoxygenase activity

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

determination method or standard

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20813&geneProductId=UniProtKB:P20813

determination method or standard

metal ion binding

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

oxidoreductase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

steroid hydroxylase activity

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

monooxygenase activity

determination method or standard

4 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20813&geneProductId=UniProtKB:P20813

determination method or standard

10 September 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20813&geneProductId=UniProtKB:P20813

determination method or standard

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20813&geneProductId=UniProtKB:P20813

determination method or standard

10 September 2018

Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20813&geneProductId=UniProtKB:P20813

determination method or standard

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

determination method or standard

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

determination method or standard

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

8 April 2019

Crystal structure of a cytochrome P450 2B6 genetic variant in complex with the inhibitor 4-(4-chlorophenyl)imidazole at 2.0-A resolution

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

monooxygenase activity

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

8 April 2019

Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

organelle membrane

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

intracellular membrane-bounded organelle

determination method or standard

1 reference

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P20813&geneProductId=UniProtKB:P20813

determination method or standard

endoplasmic reticulum

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

biological process

steroid metabolic process

determination method or standard

1 reference

8 April 2019

Identification of the human cytochrome P450 enzymes involved in the in vitro biotransformation of lynestrenol and norethindrone

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

epoxygenase P450 pathway

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

cellular ketone metabolic process

determination method or standard

1 reference

8 April 2019

Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

organic acid metabolic process

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

xenobiotic metabolic process

determination method or standard

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

8 April 2019

Crystal structure of a cytochrome P450 2B6 genetic variant in complex with the inhibitor 4-(4-chlorophenyl)imidazole at 2.0-A resolution

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20813

determination method or standard

physically interacts with

enzyme inhibitor

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

language of work or name

17 August 2016

http://purl.uniprot.org/uniprot/P20813

1 reference

Identifiers.org

cytochrome P450, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P20813

Identifiers

MeSH descriptor ID

subject named as

Cytochrome P-450 CYP2B6

0 references

D08.244.453.005.575

0 references

D08.244.453.491.344

0 references

D08.811.682.690.708.170.010.575

0 references

D08.811.682.690.708.170.450.344

0 references

D12.776.422.220.453.010.575

0 references

D12.776.422.220.453.491.344

0 references

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000324648

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000324648

ENSP00000470582

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000470582

ENSP00000496294

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000496294

PDB structure ID

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

UniProt protein ID

4 August 2016

language of work or name

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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