SLC23A2

Solute carrier family 23 member 2 is a protein that in humans is encoded by the SLC23A2 gene.^[5][6][7]

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SLC23A2
Identifiers
Aliases	SLC23A2, NBTL1, SLC23A1, SVCT2, YSPL2, hSVCT2, solute carrier family 23 member 2
External IDs	OMIM: 603791; MGI: 1859682; HomoloGene: 68440; GeneCards: SLC23A2; OMA:SLC23A2 - orthologs
Gene location (Human) Chr. Chromosome 20 (human)[1] Band 20p13 Start 4,852,356 bp[1] End 5,010,293 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 F2 Start 131,894,416 bp[2] End 131,987,028 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right adrenal cortex left adrenal cortex lateral nuclear group of thalamus Brodmann area 10 Epithelium of choroid plexus paraflocculus of cerebellum cerebellar vermis pars compacta right lobe of liver subthalamic nucleus Top expressed in choroid plexus of fourth ventricle secondary oocyte gastrula zygote primary visual cortex perirhinal cortex CA3 field entorhinal cortex Epithelium of choroid plexus superior frontal gyrus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleobase transmembrane transporter activity transporter activity L-ascorbate:sodium symporter activity symporter activity L-ascorbic acid transmembrane transporter activity transmembrane transporter activity Cellular component cytoplasm membrane basal plasma membrane basolateral plasma membrane apical plasma membrane plasma membrane integral component of plasma membrane integral component of membrane contractile fiber Biological process sodium ion transport ion transport response to oxidative stress L-ascorbic acid transmembrane transport nucleobase transport transmembrane transport nucleobase-containing compound metabolic process L-ascorbic acid metabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9962 54338 Ensembl ENSG00000089057 ENSMUSG00000027340 UniProt Q9UGH3 Q9EPR4 RefSeq (mRNA) NM_005116 NM_203327 NM_018824 NM_001355430 NM_001355431 RefSeq (protein) NP_005107 NP_976072 NP_061294 NP_001342359 NP_001342360 Location (UCSC) Chr 20: 4.85 – 5.01 Mb Chr 2: 131.89 – 131.99 Mb PubMed search [3] [4]
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The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two required transporters and the encoded protein accounts for tissue-specific uptake of vitamin C. Previously, this gene had an official symbol of SLC23A1.^[7]