7 Bible Verses about Despondency, Causes Of

And Jacob tore his clothes and put sackcloth on his loins and mourned for his son many days. And all his sons and daughters tried to console him, but he refused to be consoled. And he said, "No, I shall go down to my son, to Sheol, mourning." And his father wept for him.

A writing of Hezekiah, king of Judah, when he was sick and had recovered from his sickness: I was the one who said, "I must go in the quiet of my days; I am summoned through the gates of Sheol [for] the rest of my years." I said, "I shall not see Yah! Yah in the land of the living! I shall no more look at humankind among [the] inhabitants of [the] world.read more.
My dwelling place is pulled up and removed from me like the tent of my shepherd; I have rolled up my life like weaver. He cuts me off from [the] thrum; from day to night you bring me to an end.

So then, you should rather forgive and comfort him, lest somehow this person should be overwhelmed by excessive sorrow.

And it happened, the one who presented his offering on the first day [was] Nahshon son of Amminadab from the tribe of Judah. His offering [was] one plate of silver--its weight was one hundred and thirty shekels--[and] one silver bowl [weighing] seventy shekels according to the sanctuary shekel, {both of them} filled [with] finely milled flour mixed with oil as a grain offering;

For even [when] we arrived in Macedonia, our body had no rest, but we were afflicted in every [way]--quarrels outside, fears within. But God, who comforts the humble, comforted us by the coming of Titus,

The king was upset, and he went up to the upper room of the gate and wept. He said as he went, "My son, Absalom, my son, my son, Absalom. {If only} I had died instead of you, Absalom, my son, my son."

In the morning you shall say, '{If only it was evening}!' and in the evening you shall say '{If only it was morning}!' because of the dread of your heart that you shall feel, and because of the sight of your eyes that you shall see.