File:3D-Multi-Cell-Simulation-of-Tumor-Growth-and-Angiogenesis-pone.0007190.s003.ogv
From Wikimedia Commons, the free media repository
Jump to navigation
Jump to search
No higher resolution available.
3D-Multi-Cell-Simulation-of-Tumor-Growth-and-Angiogenesis-pone.0007190.s003.ogv (Ogg Theora video file, length 40 s, 270 × 270 pixels, 1.62 Mbps, file size: 7.73 MB)
File information
Structured data
Captions
Summary
[edit]Description3D-Multi-Cell-Simulation-of-Tumor-Growth-and-Angiogenesis-pone.0007190.s003.ogv |
English: Initially, the tumor grows exponentially. When oxygen level drops below a threshold, the normal tumor cells become hypoxic and start secreting a long-diffusing proangiogenic factor. At this stage, the tumor reaches a maximum diameter of about 300 micrometers. The activated neovascular cells in the pre-existing vasculature respond to the pro-angiogenic factors both by chemotaxing towards higher concentrations of the proangiogenic field and by forming new blood vessels via angiogenesis. The tumor-induced neovascular network enhances oxygen supply and tumor growth. Total movie time = 75 days. Time interval between frames = 6 hours. The camera rotates at a rate of 0.1 degree per frame. Cell types: Green: normal; yellow: hypoxic; blue: necrotic; red: vascular; purple: neovascular. Axes are labeled in micrometer. |
||
Date | |||
Source | Movie S2 from Shirinifard A, Gens J, Zaitlen B, Popławski N, Swat M, Glazier J (2009). "3D Multi-Cell Simulation of Tumor Growth and Angiogenesis". PLOS ONE. DOI:10.1371/journal.pone.0007190. PMID 19834621. PMC: 2760204. | ||
Author | Shirinifard A, Gens J, Zaitlen B, Popławski N, Swat M, Glazier J | ||
Permission (Reusing this file) |
|
||
Provenance InfoField |
|
File history
Click on a date/time to view the file as it appeared at that time.
Date/Time | Thumbnail | Dimensions | User | Comment | |
---|---|---|---|---|---|
current | 08:25, 31 October 2012 | 40 s, 270 × 270 (7.73 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
You cannot overwrite this file.
File usage on Commons
There are no pages that use this file.
Transcode status
Update transcode statusMetadata
This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.
Author | Shirinifard A, Gens J, Zaitlen B, Pop?awski N, Swat M, Glazier J |
---|---|
Usage terms | http://creativecommons.org/licenses/by/3.0/ |
Image title | Initially, the tumor grows exponentially. When oxygen level drops below a threshold, the normal tumor cells become hypoxic and start secreting a long-diffusing proangiogenic factor. At this stage, the tumor reaches a maximum diameter of about 300 micrometers. The activated neovascular cells in the pre-existing vasculature respond to the pro-angiogenic factors both by chemotaxing towards higher concentrations of the proangiogenic field and by forming new blood vessels via angiogenesis. The tumor-induced neovascular network enhances oxygen supply and tumor growth. Total movie time? |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2009 |