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Folin's reagent or sodium 1,2-naphthoquinone-4-sulfonate is a chemical reagent used as a derivatizing agent to measure levels of amines and amino acids. The reagent reacts with them in alkaline solution to produce a fluorescent material that can be easily detected. This should not be confused with Folin-Ciocalteu reagent, that is used to detect phenolic compounds. The Folin reagent can be used with an acidic secondary reagent to distinguish MDMA and related compounds from PMMA and related compounds.

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  • Folin-Reagenz (de)
  • Reactivo de Folin (es)
  • Folin's reagent (en)
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  • Das Folin-Reagenz, synonym Natrium-1,2-naphthochinon-4-sulfonat ist ein Nachweisreagenz für Amine einschließlich Aminosäuren aus der Gruppe der Naphthochinone. Unter diesem Namen sind mehrere Nachweisreagenzen bekannt, zum Beispiel auch eine wässrige Lösung mit Ammoniumsulfat, Uranylacetat und Essigsäure zum Harnsäure-Nachweis. Das Folin-Reagenz ist auch nicht identisch zu dem Folin-Ciocalteu-Reagenz und dem Folin-Denis-Reagenz. Sie wurde nach dem schwedisch-amerikanischen Biochemiker Otto Knut Olof Folin (1867–1934) benannt. (de)
  • Folin's reagent or sodium 1,2-naphthoquinone-4-sulfonate is a chemical reagent used as a derivatizing agent to measure levels of amines and amino acids. The reagent reacts with them in alkaline solution to produce a fluorescent material that can be easily detected. This should not be confused with Folin-Ciocalteu reagent, that is used to detect phenolic compounds. The Folin reagent can be used with an acidic secondary reagent to distinguish MDMA and related compounds from PMMA and related compounds. (en)
  • El reactivo de Folin o 1,2-naftoquinona-4-sulfonato de sodio es un reactivo químico usado para medir los niveles de aminas y aminoácidos.​ El reactivo produce un color rojo brillante en soluciones alcalinas, y es también fluorescente.​ El reactivo de Folin no debe ser confundido con el reactivo de Folin-Ciocalteu, que es una mezcla de y molibdato de sodio, usado para detectar compuestos fenólicos (es)
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