About: CD94/NKG2

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CD94/NKG2 is a family of C-type lectin receptors which are expressed predominantly on the surface of NK cells and a subset of CD8+ T-lymphocyte. These receptors stimulate or inhibit cytotoxic activity of NK cells, therefore they are divided into activating and inhibitory receptors according to their function. CD94/NKG2 recognize nonclassical MHC glycoproteins class I (HLA-E in human and Qa-1 molecules in the mouse).

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  • CD94/NKG2 jsou receptory C-lektinového typu, které jsou exprimovány na povrchu NK buněk a některých CD8+ T-lymfocytů. Spouští či tlumí cytotoxickou aktivitu NK buněk, podle funkce se tedy dělí na aktivační a inhibiční. Rozpoznávají převážně neklasické MHC glykoproteiny I. třídy, u člověka molekuly HLA-E a u myši Qa-1. (cs)
  • CD94/NKG2 is a family of C-type lectin receptors which are expressed predominantly on the surface of NK cells and a subset of CD8+ T-lymphocyte. These receptors stimulate or inhibit cytotoxic activity of NK cells, therefore they are divided into activating and inhibitory receptors according to their function. CD94/NKG2 recognize nonclassical MHC glycoproteins class I (HLA-E in human and Qa-1 molecules in the mouse). (en)
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  • CD94/NKG2 jsou receptory C-lektinového typu, které jsou exprimovány na povrchu NK buněk a některých CD8+ T-lymfocytů. Spouští či tlumí cytotoxickou aktivitu NK buněk, podle funkce se tedy dělí na aktivační a inhibiční. Rozpoznávají převážně neklasické MHC glykoproteiny I. třídy, u člověka molekuly HLA-E a u myši Qa-1. (cs)
  • CD94/NKG2 is a family of C-type lectin receptors which are expressed predominantly on the surface of NK cells and a subset of CD8+ T-lymphocyte. These receptors stimulate or inhibit cytotoxic activity of NK cells, therefore they are divided into activating and inhibitory receptors according to their function. CD94/NKG2 recognize nonclassical MHC glycoproteins class I (HLA-E in human and Qa-1 molecules in the mouse). (en)
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  • CD94/NKG2 (cs)
  • CD94/NKG2 (en)
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