Denise Grimsley (born September 21, 1959) is a Republican member of the Florida State Senate, representing parts of Central and Southwest Florida since 2012. She has represented the 26th district, which includes Highlands, Okeechobee, Glades, DeSoto, Hardee, southern Polk, eastern Charlotte, and northern Lee Counties, since 2016, after being redistricted from the 21st district. She previously served four terms in the Florida House of Representatives, representing the Highlands County-based 77th district from 2004 to 2012.