Abstract

We have developed a laser-scanning optical-resolution photoacoustic microscopy method that can potentially fuse with existing optical microscopic imaging modalities. To acquire an image, the ultrasonic transducer is kept stationary during data acquisition, and only the laser light is raster scanned by an x–y galvanometer scanner. A lateral resolution of $7.8\mu \mathrm{m}$ and a circular field of view with a diameter of $6\mathrm{mm}$ were achieved in an optically clear medium. Using a laser system working at a pulse repetition rate of $1024\mathrm{Hz}$, the data acquisition time for an image consisting of $256\times 256\text{\hspace{0.17em} pixels}$ was less than 2 min.

© 2009 Optical Society of America

Simultaneous multimodal imaging with integrated photoacoustic microscopy and optical coherence tomography

Shuliang Jiao, Zhixing Xie, Hao F. Zhang, and Carmen A. Puliafito
Opt. Lett. 34(19) 2961-2963 (2009)

Hybrid-scanning optical-resolution photoacoustic microscopy for in vivo vasculature imaging

Bin Rao, Li Li, Konstantin Maslov, and Lihong Wang
Opt. Lett. 35(10) 1521-1523 (2010)

Real-time four-dimensional optical-resolution photoacoustic microscopy with Au nanoparticle-assisted subdiffraction-limit resolution

Bin Rao, Konstantin Maslov, Amos Danielli, Ruimin Chen, K. Kirk Shung, Qifa Zhou, and Lihong V. Wang
Opt. Lett. 36(7) 1137-1139 (2011)

Fast voice-coil scanning optical-resolution photoacoustic microscopy

Lidai Wang, Konstantin Maslov, Junjie Yao, Bin Rao, and Lihong V. Wang
Opt. Lett. 36(2) 139-141 (2011)

Real-time GPU-accelerated processing and volumetric display for wide-field laser-scanning optical-resolution photoacoustic microscopy

Heesung Kang, Sang-Won Lee, Eun-Soo Lee, Se-Hwa Kim, and Tae Geol Lee
Biomed. Opt. Express 6(12) 4650-4660 (2015)