Patterns of HIV-1 Protein Interaction Identify Perturbed Host-Cellular Subsystems
Figure 2
An example portion of the interactions matrix used in biclustering.
(A) Shows an example portion of the interactions matrix. ‘1’ represents the presence of a given interaction, while ‘0’ the absence of that interaction, between a human protein interactant (shown left) and an HIV protein; the interaction having a given outcome (shown above). The entire matrix was biclustered to identify sets of host proteins that undergo the same set of HIV-1 interactions. (B) Shows an example bicluster that would be found in the portion of matrix given in (A).