Mechanisms underlying a thalamocortical transformation during active tactile sensation
Fig 8
Effects of varying intracortical recurrent excitatory conductances gEE on the function of L4E neurons.
(a) The circuit with changing gEE emphasized in green. (b) νE vs. AT during whisker movements only, for 11 values of gEE from 0 (light green) to 0.4 mS/cm2, that is twice the reference parameter value (dark green). Recurrent excitation gEE increases νE while not affecting the slope of the νE-AT curve far from spiking threshold substantially. (c) RT, RE and RI as functions of gEE. Other parameters: AT = 14 spikes/s, CT = 0.6. (d) PSTH aligned to touch onset for L4E and without recurrent excitation (gEE = 0 mS/cm2). (e) Same as C for L4I. (f-g) Same as c-d for gEE = 0.2 mS/cm2. (h-i): Same as c-d for gEE = 0.35 mS/cm2. Beyond ~gEE = 0.4 mS/cm2 the network exhibits runaway excitation.