Zeatin

Zeatin
Names
	IUPAC name (E)-2-methyl-4-(7H-purin-6-ylamino)but-2-en-1-ol
Identifiers
CAS Number	1637-39-4 ;
3D model (JSmol)	Interactive image;
ChemSpider	395716;
PubChem CID	449093;
CompTox Dashboard (EPA)	DTXSID10859662 ;
	InChI InChI=1S/C10H13N5O/c1-7(4-16)2-3-11-9-8-10(13-5-12-8)15-6-14-9/h2,5-6,16H,3-4H2,1H3,(H2,11,12,13,14,15)/b7-2+ Key: UZKQTCBAMSWPJD-FARCUNLSSA-N; InChI=1/C10H13N5O/c1-7(4-16)2-3-11-9-8-10(13-5-12-8)15-6-14-9/h2,5-6,16H,3-4H2,1H3,(H2,11,12,13,14,15)/b7-2+ Key: UZKQTCBAMSWPJD-FARCUNLSBM;
	SMILES CC(=CCNC1=NC =NC2=C1NC=N2)CO;
Properties
Chemical formula	C10H13N5O
Molar mass	219.248 g·mol−1
Appearance	Off-white to yellow crystalline powder
Melting point	208−210 °C
Solubility in 1M NaOH	Soluble
Hazards
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	2200 mg/kg (mouse, transperitoneal)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Zeatin is a plant hormone derived from the purine adenine. It is a member of the plant growth hormone family known as cytokinins. Zeatin was first discovered in immature corn kernels from the genus Zea. It promotes growth of lateral buds and stimulates cell division to produce bushier plants if sprayed on meristems.^{[citation needed]}

Zeatin and derivatives were discovered to be the primary active ingredient in coconut milk, which has long been known to actively induce plant growth.^[1]

Zeatin has been reported to have several in vitro anti-aging effects on human skin fibroblasts.^[2]

Toxicology

The acute transperitoneal toxicity in mice (LD₅₀) is 2200 mg/kg.

Application

Promotes callus initiation when combined with auxin, concentration 1 ppm.
Promotes fruit set. Zeatin 100 ppm + GA3 500 ppm + NAA 20 ppm, sprayed at 10th, 25th, 40th day after blossom.
Retards yellowing for vegetables, 20 ppm, sprayed.
Causes auxiliary stems to grow and flower.

It can also be applied to stimulate seed germination and seedling grow

^ David W. S. Mok, Machteld C. Mok (1994). Cytokinins: Chemistry, Activity, and Function. CRC Press. p. 8. ISBN 0-8493-6252-0. (available from Google books)
^ Rattan, S.I.S. and Sodagam, L. (2005). "Gerontomodulatory and youth-preserving effects of zeatin on human skin fibroblasts undergoing aging in vitro". Rejuvenation Research. 8 (1): 46–57. doi:10.1089/rej.2005.8.46. PMID 15798374.{{cite journal}}: CS1 maint: multiple names: authors list (link)

External links

Cytokinins

[1] David W. S. Mok, Machteld C. Mok (1994). Cytokinins: Chemistry, Activity, and Function. CRC Press. p. 8. ISBN 0-8493-6252-0. (available from Google books)

[2] Rattan, S.I.S. and Sodagam, L. (2005). "Gerontomodulatory and youth-preserving effects of zeatin on human skin fibroblasts undergoing aging in vitro". Rejuvenation Research. 8 (1): 46–57. doi:10.1089/rej.2005.8.46. PMID 15798374.{{cite journal}}: CS1 maint: multiple names: authors list (link)

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