Pope John may refer to:
- Pope John I (523–526)
- Pope John II (533–535)
- Pope John III (561–574)
- Pope John IV (640–642)
- Pope John V (685–686)
- Pope John VI (701–705)
- Pope John VII (705–707)
- Antipope John VIII (844)
- Pope John VIII (872–882)
- Pope John IX (898–900)
- Pope John X (914–928)
- Pope John XI (931–935)
- Pope John XII (955–964)
- Pope John XIII (965–972)
- Pope John XIV (983–984)
- Pope John XV (985–996)
- Antipope John XVI (997–998)
- Pope John XVII (1003)
- Pope John XVIII (1003–1009)
- Pope John XIX (1024–1032)
- Pope John XX (the number XX was skipped)
- Pope John XXI (1276–1277)
- Pope John XXII (1316–1334)
- Antipope John XXIII (1410–1415)
- Pope John XXIII (1958–1963)
- Another 19 Popes John in the List of Coptic Orthodox Popes of Alexandria