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Protein-coding gene in humans
Carboxypeptidase A5 is an enzyme that in humans is encoded by the CPA5 gene .[ 5] [ 6]
Carboxypeptidases have functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Members of the A/B subfamily of carboxypeptidases, such as CPA5, contain an approximately 90-amino acid pro region that assists in the folding of the active carboxypeptidase domain. Cleavage of the pro region activates the enzyme (Wei et al., 2002).[supplied by OMIM][ 6]
^ a b c GRCh38: Ensembl release 89: ENSG00000158525 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029788 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Wei S, Segura S, Vendrell J, Aviles FX, Lanoue E, Day R, Feng Y, Fricker LD (Apr 2002). "Identification and characterization of three members of the human metallocarboxypeptidase gene family" . J Biol Chem . 277 (17): 14954–64. doi :10.1074/jbc.M112254200 . PMID 11836249 .
^ a b "Entrez Gene: CPA5 carboxypeptidase A5" .
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