The 2000-01 season is River Plate's 71nd season in the Argentine Primera División.
The season was split into two tournaments (format adopted since 1990–91 season) Apertura (Opening) 2000 (from August to December 2000), and Clausura (Closing) 2001 (from February to June 2001).
Note: Flags indicate national team as defined under FIFA eligibility rules, some limited exceptions apply. Players may hold more than one non-FIFA nationality.
Note: Flags indicate national team as defined under FIFA eligibility rules, some limited exceptions apply. Players may hold more than one non-FIFA nationality.